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1.发明申请Electrophysiological sensor, weak electrical signal conditioning circuit and method for controlling said circuit 审中-公开电生理传感器，弱电信号调理电路及控制电路的方法公开(公告)号：US20090024017A1
公开(公告)日：2009-01-22
申请号：US12107392
申请日：2008-04-22
申请人： Giulio Ruffini , Stephen Dunne , Esteve Farres
发明人： Giulio Ruffini , Stephen Dunne , Esteve Farres
IPC分类号： A61B5/05
CPC分类号： A61B5/0408 , A61B5/0478 , A61B5/0492 , A61B5/685 , A61B5/7232 , A61B2562/0215 , A61B2562/046
摘要： An electrophysiological sensor, weak electrical signal conditioning circuit and method for controlling the circuit as provided. The sensor includes rigid filiform conducting nanostructures connected to a conducting substrate and operable to penetrate an organic tissue. The circuit includes an instrumentation amplifier with an input connected to a first electrode in contact with a first area of a medium, and a second input; a voltage generating device connected to an electrode in contact with a second area of the medium for applying a continuous reference signal to it; a compensator, electrically insulated from the device, for compensating the direct current offsets of a weak electrical signal received by the first electrode, generating a signal with a reference voltage with a value which can be modified by a control system, and supplying it to the second input. A method is also provided for controlling the circuit.
摘要翻译： 一种电生理传感器，弱电信号调节电路及其控制方法。 传感器包括连接到导电基底并可操作以穿透有机组织的刚性丝状导电纳米结构。 该电路包括仪表放大器，其输入端连接到与介质的第一区域接触的第一电极和第二输入端; 连接到与介质的第二区域接触的电极的电压产生装置，用于向其施加连续的参考信号; 补偿器，与所述装置电绝缘，用于补偿由所述第一电极接收的弱电信号的直流偏移，产生具有可由控制系统修改的值的参考电压的信号，并将其提供给 第二个输入。 还提供了一种用于控制电路的方法。
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公开(公告)号：US20070272763A1
公开(公告)日：2007-11-29
申请号：US11576853
申请日：2005-10-06
申请人： Stephen Dunne , Marc Rohrschneider , Achim Moser
发明人： Stephen Dunne , Marc Rohrschneider , Achim Moser
CPC分类号： A61M15/0028 , A61M11/001 , A61M11/002 , A61M11/02 , A61M15/0003 , A61M15/002 , A61M15/0031 , A61M15/0033 , A61M15/0045 , A61M15/0048 , A61M15/0051 , A61M2202/064 , A61M2205/073 , A61M2205/8225 , A61M2206/16
摘要： A dispensing device, a storage device and a method for dispensing powder in which powder is dispensed through a duct with a flat cross section to de-agglomerate the powder and to generate a spray with fine particle size. A storage chamber for the powder may be closed by a bursting element which is burst by pressurized gas for discharging the powder, the gas pressure reaching or exceeding a peak value before the bursting element bursts so that the powder is dispensed at a lower gas pressure. The powder may be forced through the duct by a gas pressure of less than 300 kPa to de-agglomerate the powder and/or to generate the spray. The storage device can have multiple storage chambers and associated ducts or nozzles, so that each dose of powder can be dispensed through a separate duct or nozzle.
摘要翻译： 分配装置，存储装置和分配粉末的方法，其中通过具有平坦横截面的管道分配粉末，以使粉末解聚并产生具有细粒度的喷雾。 用于粉末的储存室可以由爆破元件封闭，该破裂元件通过用于排出粉末的加压气体爆裂，气体压力在爆裂元件爆发之前达到或超过峰值，使得粉末以较低的气体压力被分配。 可以通过小于300kPa的气体压力将粉末强制通过管道，以使粉末脱团解和/或产生喷雾。 存储装置可以具有多个存储室和相关联的管道或喷嘴，使得可以通过单独的管道或喷嘴分配每一剂量的粉末。
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公开(公告)号：US20060032494A1
公开(公告)日：2006-02-16
申请号：US11249268
申请日：2005-10-14
申请人： Klaus Kadel , Johannes Geser , Joachin Eicher , Bernhard Freund , Stephen Dunne , Wulf Bachtler
发明人： Klaus Kadel , Johannes Geser , Joachin Eicher , Bernhard Freund , Stephen Dunne , Wulf Bachtler
CPC分类号： B01D67/0062 , A61M11/00 , A61M15/00 , A61M2205/0233 , B01D39/16 , B01D39/2003 , B01D39/2027 , B01D39/2068 , B01D46/0023 , B01D46/12 , B01D46/40 , B01D46/521 , B01D67/003 , B01D67/0058 , B01D67/0069 , B01D71/022 , B01D2275/206 , B01D2325/021 , B01D2325/04 , B05B15/40
摘要： A microstructured filter is presented having an inlet for unfiltered fluid; an outlet for filtered fluid; a plurality of projections, which form at least one row in a mutually juxtaposed relationship across the filter, that project out of a base plate and are an integral component of the base plate; a plurality of passages between the projections; and a cover plate which is securable to the base plate to cover the projections and the passages. The passages form a plurality of through paths from the inlet to the outlet. The inlet includes an elongate inlet slot for the unfiltered fluid that extends over approximately the entire filter width and is approximately as high as the projection on the outlet side of the filter.
摘要翻译： 呈现出具有未过滤流体入口的微结构过滤器; 过滤流体出口; 多个突起，其跨过过滤器以相互并列的关系形成至少一排，从基板突出并且是基板的整体部件; 突起之间的多个通道; 以及可以固定到基板以覆盖突起和通道的盖板。 通道形成从入口到出口的多个通路。 入口包括用于未过滤流体的细长入口槽，其大致跨过整个过滤器宽度延伸，并且大致与过滤器出口侧上的突起一样高。
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4.发明申请公开(公告)号：US20050150378A1
公开(公告)日：2005-07-14
申请号：US10755453
申请日：2004-01-12
申请人： Stephen Dunne , Peter Coughlin , Rustam Sethna
发明人： Stephen Dunne , Peter Coughlin , Rustam Sethna
CPC分类号： B01D53/261 , B01D53/0462 , B01D53/06 , B01D2253/108 , B01D2253/25 , B01D2256/24 , B01D2256/245 , B01D2257/2045 , B01D2257/2066 , B01D2257/80 , B01D2259/40052 , B01D2259/40081 , B01D2259/4009 , B01D2259/402
摘要： Using a high pressure rotary adsorbent wheel, a high value compressed gas feed can be purified by concentrating the impurity such as water, condensing it out, before final purification. Instead of exhausting gas from the system, the effluent can be put back into the feed at a point prior to condensation of the high value gas feed, and therefore the entire feed is purified without any high value gas feed going into a waste stream.
摘要翻译： 使用高压旋转吸附轮，可以在最终净化之前将杂质如水浓缩，冷凝出来，从而净化高价值的压缩气体进料。 代替从系统中排出气体，流出物可以在高价值气体进料冷凝之前的某一点被放回到进料中，因此整个进料被纯化，没有任何高价值的气体进料进入废物流。
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公开(公告)号：US20050061483A1
公开(公告)日：2005-03-24
申请号：US10989153
申请日：2004-11-15
申请人： Stephen Dunne , Steven Bradley
发明人： Stephen Dunne , Steven Bradley
CPC分类号： F28D9/0031 , F25B35/04 , Y02A30/276 , Y02A30/278 , Y02B30/64
摘要： This invention provides a compact heat exchanger that has an effective geometry for heat transfer operations regardless of the heat conductivity of the material chosen for the fin materials. It has further been found that the use of adsorbent coated anodized aluminum for fin materials provides for a very efficient heat exchanger.
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公开(公告)号：US07681811B2
公开(公告)日：2010-03-23
申请号：US11764248
申请日：2007-06-18
IPC分类号： A62C2/08
CPC分类号： B05B11/3091 , A61M11/00 , A61M15/0065 , B05B1/26 , B05B15/65
摘要： The invention relates to a nozzle system for a delivery device for liquids, wherein the nozzle system comprises a nozzle and a device which fixes the nozzle in the delivery device. The delivery device, an atomizer, has a liquid reservoir from which a liquid is forced through the nozzle under pressure. The nozzle fixing means may itself be secured by a second fixing, e.g., in the form of a check nut, or the fixing may itself be a check nut. According to the invention the fixing means on the nozzle outlet side has a specific geometry which minimizes the proportion of dispensed liquid deposited on the fixing means. Preferably, the present invention is part of a propellant-free device for nebulizing pharmaceutical liquids.
摘要翻译： 本发明涉及一种用于液体输送装置的喷嘴系统，其中喷嘴系统包括喷嘴和将喷嘴固定在输送装置中的装置。 输送装置，雾化器，具有液体储存器，液体在压力下被迫使其通过喷嘴。 喷嘴固定装置本身可以通过例如以止回螺母的形式的第二固定来固定，或者固定本身可以是止回螺母。 根据本发明，喷嘴出口侧上的固定装置具有特定的几何形状，其使沉积在固定装置上的分配液体的比例最小化。 优选地，本发明是用于雾化药物液体的无推进剂的装置的一部分。
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公开(公告)号：US20080001008A1
公开(公告)日：2008-01-03
申请号：US11749263
申请日：2007-05-16
申请人： Ralf Thoemmes , Timo Von Brunn , Marc Rohrschneider , Stephen Dunne , Anke Klaer
发明人： Ralf Thoemmes , Timo Von Brunn , Marc Rohrschneider , Stephen Dunne , Anke Klaer
CPC分类号： A61M15/009 , A61M11/006 , A61M11/02 , A61M15/00 , A61M15/0026 , A61M15/0045 , A61M15/0048 , A61M15/005 , A61M15/0061 , A61M15/0075 , A61M15/0083 , A61M2202/064
摘要： An atomizer, a reservoir and a method are proposed for the delivery and in particular, the atomization of a formulation, particularly a powder. A pump and a spring are arranged inside the annular reservoir, the pump and the spring being moveable radially and in a sliding manner. The pump is actuated by the spring to put air under pressure for discharging powder from the reservoir. The reservoir comprises receptacles or cavities, each of which has an insert with a respective dose of the formulation. The receptacles are constructed as separate parts and/or arranged on a common or annular carrier and/or are sealed separately and/or on its outer circumferential periphery. The spring is tensioned and the air is sucked into the pump. Then, the next receptacle and a connecting element are aligned relative to each other. Finally, the aligned receptacle is pierced by the connecting element for supplying the air.
摘要翻译： 提出了雾化器，储存器和方法用于递送，特别是制剂的雾化，特别是粉末。 泵和弹簧布置在环形容器内部，泵和弹簧可以径向和滑动地移动。 泵由弹簧致动，以将空气压在压力下，从储存器排出粉末。 储存器包括插座或空腔，每个插座具有具有相应剂量的制剂的插入物。 容器被构造为分开的部件和/或布置在共同的或环形的载体上和/或分别密封和/或在其外圆周周边上密封。 弹簧张紧，空气被吸入泵中。 然后，下一个插座和连接元件相对于彼此对准。 最后，对准的容器被用于供应空气的连接元件刺穿。
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公开(公告)号：US07284713B2
公开(公告)日：2007-10-23
申请号：US10982991
申请日：2004-11-05
CPC分类号： B05B11/3091 , A61M11/00 , A61M15/0065 , B05B1/26 , B05B15/65
摘要： The invention relates to a nozzle system for a delivery device for liquids, wherein the nozzle system comprises a nozzle and a device which fixes the nozzle in the delivery device. The delivery device, an atomiser, has a liquid reservoir from which a liquid is forced through the nozzle under pressure. The nozzle fixing means may itself be secured by a second fixing, e.g., in the form of a check nut, or the fixing may itself be a check nut. According to the invention the fixing means on the nozzle outlet side has a specific geometry which minimizes the proportion of dispensed liquid deposited on the fixing means.Preferably, the present invention is part of a propellant-free device for nebulizing pharmaceutical liquids.
摘要翻译： 本发明涉及一种用于液体输送装置的喷嘴系统，其中喷嘴系统包括喷嘴和将喷嘴固定在输送装置中的装置。 输送装置，雾化器，具有液体储存器，液体在压力下被迫使其通过喷嘴。 喷嘴固定装置本身可以通过例如以止回螺母的形式的第二固定来固定，或者固定本身可以是止回螺母。 根据本发明，喷嘴出口侧上的固定装置具有特定的几何形状，其使沉积在固定装置上的分配液体的比例最小化。 优选地，本发明是用于雾化药物液体的无推进剂的装置的一部分。
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9.发明授权公开(公告)号：US07699052B2
公开(公告)日：2010-04-20
申请号：US10648132
申请日：2003-08-26
申请人： Joerg Schiewe , Gilbert Wuttke , Bernd Zierenberg , Stephen Dunne , Horst Wergen
发明人： Joerg Schiewe , Gilbert Wuttke , Bernd Zierenberg , Stephen Dunne , Horst Wergen
CPC分类号： B05B11/0054 , A61M15/0028 , A61M15/0081 , B05B11/02 , B05B11/3091
摘要： The present invention relates to a propellant-gas-free apparatus for the dispensing of liquids, a container cartridge suitable for this for storing the liquid and the ensemble comprising both. The invention comprises a device for the exertion of pressure and for accommodating a container cartridge and a container cartridge in which the dispensing facility is integrated.
摘要翻译： 本发明涉及一种用于分配液体的无气体推进剂装置，适用于储存液体的容器盒和包括两者的组合物。 本发明包括用于施加压力并用于容纳集装箱的装置和其中分配设备被集成的容器盒。
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公开(公告)号：US20070257134A1
公开(公告)日：2007-11-08
申请号：US11764248
申请日：2007-06-18
IPC分类号： B05B7/04
CPC分类号： B05B11/3091 , A61M11/00 , A61M15/0065 , B05B1/26 , B05B15/65
摘要： The invention relates to a nozzle system for a delivery device for liquids, wherein the nozzle system comprises a nozzle and a device which fixes the nozzle in the delivery device. The delivery device, an atomizer, has a liquid reservoir from which a liquid is forced through the nozzle under pressure. The nozzle fixing means may itself be secured by a second fixing, e.g., in the form of a check nut, or the fixing may itself be a check nut. According to the invention the fixing means on the nozzle outlet side has a specific geometry which minimizes the proportion of dispensed liquid deposited on the fixing means. Preferably, the present invention is part of a propellant-free device for nebulizing pharmaceutical liquids.
摘要翻译： 本发明涉及一种用于液体输送装置的喷嘴系统，其中喷嘴系统包括喷嘴和将喷嘴固定在输送装置中的装置。 输送装置，雾化器，具有液体储存器，液体在压力下被迫使其通过喷嘴。 喷嘴固定装置本身可以通过例如以止回螺母的形式的第二固定来固定，或者固定本身可以是止回螺母。 根据本发明，喷嘴出口侧上的固定装置具有特定的几何形状，其使沉积在固定装置上的分配液体的比例最小化。 优选地，本发明是用于雾化药物液体的无推进剂的装置的一部分。
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