TNF superfamily member light fusion proteins
    6.
    发明授权
    TNF superfamily member light fusion proteins 有权
    TNF超家族成员光融合蛋白

    公开(公告)号:US08580273B2

    公开(公告)日:2013-11-12

    申请号:US13403826

    申请日:2012-02-23

    摘要: The present invention refers to fusion proteins comprising a TNF superfamily (TNFSF) cytokine or a receptor binding domain thereof fused to a trimerization domain and a nucleic acid molecule encoding the fusion protein. The fusion protein is present as a trimeric complex or as an oligomer thereof and is suitable for therapeutic, diagnostic and/or research applications.

    摘要翻译: 本发明涉及融合蛋白质,其包含融合到三聚结构域的TNF超家族(TNFSF)细胞因子或其受体结合结构域和编码融合蛋白的核酸分子。 融合蛋白以三聚体复合物或其低聚物形式存在,并且适用于治疗,诊断和/或研究应用。