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公开(公告)号：US08778696B2
公开(公告)日：2014-07-15
申请号：US12850949
申请日：2010-08-05
申请人： Oliver Gutmann , Edwin Oosterbroek , Michael Glauser , Michael Andreas Heinrich , Jean-Pierre Bolliger , Emad Sarofim , Rainer D. Jaeggi
发明人： Oliver Gutmann , Edwin Oosterbroek , Michael Glauser , Michael Andreas Heinrich , Jean-Pierre Bolliger , Emad Sarofim , Rainer D. Jaeggi
CPC分类号： G01N35/1072 , B01L3/5027 , B01L3/502715 , B01L3/502738 , B01L2200/027 , B01L2200/0621 , B01L2300/0663 , B01L2300/0816 , B01L2300/087 , B01L2300/14 , B01L2400/0487 , B01L2400/049 , B01L2400/0622 , B01L2400/0677 , G01N2035/00158 , Y10T436/2575
摘要： A microfluidic processing unit for the automated processing of liquid samples and method thereof are disclosed. In one embodiment, the unit comprises first and second main channels connected to a pump for generating a negative or positive pressure therein; a sample channel which supplies a liquid sample is connectable to a sample vessel containing the liquid sample, the sample channel communicates with the first main channel and is equipped with an on/off valve; one or more reagent channels for supplying one or more reagents, the reagent channels being connectable to reagent vessels containing reagents for reacting with the liquid samples, each of the reagent channels communicating with the first or second main channel and being equipped with an on/off valve; and a reaction chamber for reacting a sample and reagent, the reaction chamber being connected to the first and second main channels via at least one on/off valve.
摘要翻译： 公开了用于液体样品的自动处理的微流体处理单元及其方法。 在一个实施例中，该单元包括连接到泵的用于在其中产生负压或正压的第一和第二主通道; 提供液体样品的样品通道可连接到包含液体样品的样品容器，样品通道与第一主通道连通并且配备有开关阀; 用于供应一种或多种试剂的一个或多个试剂通道，所述试剂通道可连接到含有用于与液体样品反应的试剂的试剂容器，每个试剂通道与第一或第二主通道连通并且装备有开/关 阀; 以及用于使样品和试剂反应的反应室，所述反应室经由至少一个开/关阀连接到所述第一和第二主通道。
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公开(公告)号：US20110189785A1
公开(公告)日：2011-08-04
申请号：US12850949
申请日：2010-08-05
申请人： Oliver Gutmann , Edwin Oosterbroek , Michael Glauser , Michael Andreas Heinrich , Jean-Pierre Bolliger , Emad Sarofim , Rainer D. Jaeggi
发明人： Oliver Gutmann , Edwin Oosterbroek , Michael Glauser , Michael Andreas Heinrich , Jean-Pierre Bolliger , Emad Sarofim , Rainer D. Jaeggi
CPC分类号： G01N35/1072 , B01L3/5027 , B01L3/502715 , B01L3/502738 , B01L2200/027 , B01L2200/0621 , B01L2300/0663 , B01L2300/0816 , B01L2300/087 , B01L2300/14 , B01L2400/0487 , B01L2400/049 , B01L2400/0622 , B01L2400/0677 , G01N2035/00158 , Y10T436/2575
摘要： A microfluidic processing unit for the automated processing of liquid samples and method thereof are disclosed. In one embodiment, the unit comprises first and second main channels connected to a pump for generating a negative or positive pressure therein; a sample channel which supplies a liquid sample is connectable to a sample vessel containing the liquid sample, the sample channel communicates with the first main channel and is equipped with an on/off valve; one or more reagent channels for supplying one or more reagents, the reagent channels being connectable to reagent vessels containing reagents for reacting with the liquid samples, each of the reagent channels communicating with the first or second main channel and being equipped with an on/off valve; and a reaction chamber for reacting a sample and reagent, the reaction chamber being connected to the first and second main channels via at least one on/off valve.
摘要翻译： 公开了用于液体样品的自动处理的微流体处理单元及其方法。 在一个实施例中，该单元包括连接到泵的用于在其中产生负压或正压的第一和第二主通道; 提供液体样品的样品通道可连接到包含液体样品的样品容器，样品通道与第一主通道连通并且配备有开关阀; 一个或多个用于供应一种或多种试剂的试剂通道，所述试剂通道可连接到含有用于与液体样品反应的试剂的试剂容器，每个试剂通道与第一或第二主通道连通并且装备有开/关 阀; 以及用于使样品和试剂反应的反应室，所述反应室经由至少一个开/关阀连接到所述第一和第二主通道。
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公开(公告)号：US20110189052A1
公开(公告)日：2011-08-04
申请号：US12850934
申请日：2010-08-05
申请人： Rainer D. Jaeggi , Oliver Gutmann , Michael Glauser , Heinz-Michael Hein , Edwin Oosterbroek , Michael Andreas Heinrich
发明人： Rainer D. Jaeggi , Oliver Gutmann , Michael Glauser , Heinz-Michael Hein , Edwin Oosterbroek , Michael Andreas Heinrich
IPC分类号： G01N33/00
CPC分类号： G01N35/1095 , B01L2200/027 , G01N35/085 , G01N2035/00158 , G01N2035/1034
摘要： A system for the automated analysis of liquid samples having one or more processing units for reaction between the samples and one or more reagents to thereby obtain reaction products is disclosed. Disclosed also are a sample unit for supplying the samples to the one or more processing units; a reagent unit equipped with plural reagent vessels containing one or more reagents for mixing with the samples; a distribution unit for distributing fluids including the one or more reagents provided with plural distribution lines, at least some of which are connected to the reagent vessels and the one or more processing units; and at least one analytical unit for analyzing the samples based on the reaction products, in which the analytical unit may include at least one detector for detecting the reaction products.
摘要翻译： 公开了一种用于自动分析液体样品的系统，该液体样品具有一个或多个处理单元，用于样品与一种或多种试剂之间的反应，从而获得反应产物。 还公开了一种用于将样本提供给一个或多个处理单元的采样单元; 配备有多个试剂容器的试剂单元，所述试剂容器含有一种或多种用于与样品混合的试剂; 用于分配流体的分配单元，所述流体包括具有多个分配管线的一种或多种试剂，其中至少一些连接到所述试剂容器和所述一个或多个处理单元; 以及用于基于反应产物分析样品的至少一个分析单元，其中分析单元可以包括用于检测反应产物的至少一个检测器。
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公开(公告)号：US08940249B2
公开(公告)日：2015-01-27
申请号：US12850934
申请日：2010-08-05
申请人： Rainer D. Jaeggi , Oliver Gutmann , Michael Glauser , Heinz-Michael Hein , Edwin Oosterbroek , Michael Andreas Heinrich
发明人： Rainer D. Jaeggi , Oliver Gutmann , Michael Glauser , Heinz-Michael Hein , Edwin Oosterbroek , Michael Andreas Heinrich
CPC分类号： G01N35/1095 , B01L2200/027 , G01N35/085 , G01N2035/00158 , G01N2035/1034
摘要： A system for the automated analysis of liquid samples having one or more processing units for reaction between the samples and one or more reagents to thereby obtain reaction products is disclosed. Disclosed also are a sample unit for supplying the samples to the one or more processing units; a reagent unit equipped with plural reagent vessels containing one or more reagents for mixing with the samples; a distribution unit for distributing fluids including the one or more reagents provided with plural distribution lines, at least some of which are connected to the reagent vessels and the one or more processing units; and at least one analytical unit for analyzing the samples based on the reaction products, in which the analytical unit may include at least one detector for detecting the reaction products.
摘要翻译： 公开了一种用于自动分析液体样品的系统，该液体样品具有一个或多个处理单元，用于样品与一种或多种试剂之间的反应，从而获得反应产物。 还公开了一种用于将样本提供给一个或多个处理单元的采样单元; 配备有多个试剂容器的试剂单元，所述试剂容器含有一种或多种用于与样品混合的试剂; 用于分配流体的分配单元，所述流体包括具有多个分配管线的一种或多种试剂，其中至少一些连接到所述试剂容器和所述一个或多个处理单元; 以及用于基于反应产物分析样品的至少一个分析单元，其中分析单元可以包括用于检测反应产物的至少一个检测器。
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