Method for assaying histone methylation enzyme activity
    2.
    发明授权
    Method for assaying histone methylation enzyme activity 有权
    测定组蛋白甲基化酶活性的方法

    公开(公告)号:US09012166B2

    公开(公告)日:2015-04-21

    申请号:US13639334

    申请日:2011-04-15

    Abstract: Provided are a method for measuring histone methyltransferase activity, a method for screening for compounds that inhibit histone methyltransferase activity, a reagent kit for measuring histone methyltransferase activity, and a kit for screening for compounds that inhibit histone methyltransferase activity. A substrate compound represented by general formula (I): R1-X-K-R2 (I), or a salt thereof, wherein R1 represents a hydrogen atom or a protecting group for an amino terminus; X represents a peptide consisting of 0 or 1 or more amino acid residues; K represents a lysine residue; and R2 represents a dye label linked via an amide bond to the carbonyl terminus of a lysine residue, wherein the cleavage of the amide bond by peptidase changes the fluorescence property or chromogenic property of the dye label, and the methylation of the ε amino group of the lysine residue by the histone methyltransferase decreases susceptibility to peptidase, is used.

    Abstract translation: 提供了测定组蛋白甲基转移酶活性的方法,用于筛选抑制组蛋白甲基转移酶活性的化合物的方法,用于测定组蛋白甲基转移酶活性的试剂盒和用于筛选抑制组蛋白甲基转移酶活性的化合物的试剂盒。 由通式(I)表示的底物化合物:R1-X-K-R2(I)或其盐,其中R1表示氢原子或氨基末端的保护基; X表示由0或1个或更多个氨基酸残基组成的肽; K表示赖氨酸残基; R2表示通过酰胺键与赖氨酸残基的羰基末端连接的染料标记,其中通过肽酶切割酰胺键改变染料标记的荧光性质或显色性质,以及染料标记的甲基化。 使用组蛋白甲基转移酶的赖氨酸残基的氨基降低对肽酶的易感性。

    Railway-train communication apparatus
    4.
    发明授权
    Railway-train communication apparatus 有权
    铁路列车通讯设备

    公开(公告)号:US08488617B2

    公开(公告)日:2013-07-16

    申请号:US12531891

    申请日:2008-03-17

    Abstract: A railway-train communication apparatus transmits a first transmission signal flowing through an inter-car network between cars of a railway train and a second transmission signal flowing through an in-car network in each of the cars. A node device includes a first signal converter and a second signal converter that perform a signal conversion between the first transmission signal and the second transmission signal and a layer 2 switch arranged between the first signal converter and the second signal converter for connecting the first signal converter and the second signal converter. A first controller is connected to the layer 2 switch.

    Abstract translation: 铁路列车通信装置发送在铁路车辆的车辆之间流过车厢间网络的第一发送信号和流过车厢内的车内网络的第二发送信号。 节点装置包括执行第一传输信号和第二传输信号之间的信号转换的第一信号转换器和第二信号转换器,以及布置在第一信号转换器和第二信号转换器之间的第二层开关,用于将第一信号转换器 和第二信号转换器。 第一控制器连接到第2层交换机。

    Image information transmission device, image information transmission method and computer readable medium
    7.
    发明授权
    Image information transmission device, image information transmission method and computer readable medium 有权
    图像信息发送装置,图像信息发送方法和计算机可读介质

    公开(公告)号:US08456677B2

    公开(公告)日:2013-06-04

    申请号:US12787733

    申请日:2010-05-26

    Abstract: An image information transmission device includes a registration unit, a storage unit, a determination unit, and an image information transmission unit. The registration unit registers an image information transmission instruction describing a destination number specifying a destination of image information and an abbreviated number corresponding to the destination number. The storage unit stores the destination number and transmission setting information used for transmitting the image information to the destination specified by the destination number. The determination unit determines whether or not the destination number described in the image information transmission instruction is contained in the destination number. The image information transmission unit transmits the image information.

    Abstract translation: 图像信息传输装置包括注册单元,存储单元,确定单元和图像信息传输单元。 注册单元注册描述指定图像信息的目的地的目的地号码和对应于目的地号码的缩写号码的图像信息传输指令。 存储单元将用于将图像信息发送到由目的地号码指定的目的地的目的地号码和发送设置信息存储。 确定单元确定图像信息发送指令中描述的目的地号码是否包含在目的地号码中。 图像信息发送单元发送图像信息。

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