公开(公告)号：US08869585B2

公开(公告)日：2014-10-28

申请号：US12918311

申请日：2009-02-19

Applicant: Gavin Troughton ,  Peter Laitenberger

Inventor： Gavin Troughton ,  Peter Laitenberger

IPC: A61B5/1495

CPC classification number: A61B5/1495 ,  A61B2560/0223

Abstract: Methods and systems for calibrating a sensor for measuring an analyte in a patient monitoring system are disclosed. The method includes calculating sensor drift; calibrating the sensor using at least one calibration fluid; and periodically updating the sensor calibration based on the sensor drift calculation. The system adjusts a gas concentration in a fluid. The method in one of several variations includes providing a calibration fluid; setting the analyte concentration in the first fluid to a first concentration with an adjustment mechanism; measuring the first analyte concentration with the sensor; setting the analyte concentration in the first fluid to a second concentration; measuring the second analyte concentration with the sensor; and determining the calibration coefficients for the sensor from the measured first and second analyte concentrations. Some embodiments ensure that the period between recalibrations of the sensor is extended, thus reducing the number of disruptions to the sensor monitoring process.

Abstract translation: 公开了用于校准用于测量患者监测系统中的分析物的传感器的方法和系统。 该方法包括计算传感器漂移; 使用至少一个校准流体校准传感器; 并基于传感器漂移计算周期性地更新传感器校准。 系统调节流体中的气体浓度。 在多种变化之一中的方法包括提供校准流体; 将第一流体中的分析物浓度用调节机构设定为第一浓度; 用传感器测量第一分析物浓度; 将第一流体中的分析物浓度设定为第二浓度; 用传感器测量第二分析物浓度; 以及根据所测量的第一和第二分析物浓度确定所述传感器的校准系数。 一些实施例确保传感器的重新校准之间的周期延长，从而减少传感器监测过程的中断次数。

公开(公告)号：US20070134721A1

公开(公告)日：2007-06-14

申请号：US10588172

申请日：2005-02-03

Applicant: Peter Laitenberger ,  Stuart Hendry ,  Gavin Troughton

Inventor： Peter Laitenberger ,  Stuart Hendry ,  Gavin Troughton

IPC: G01N33/53 ,  C12M3/00

CPC classification number: G01N33/54373 ,  A61B5/14546 ,  A61B5/150992 ,  A61B5/157 ,  A61B5/4821 ,  A61M2202/048 ,  B01J20/268 ,  G01N2600/00

Abstract: This invention relates to a sensor suitable for detecting the presence of one or more analytes. The sensor comprises a substrate; a confinement structure disposed on the substrate, wherein the confinement structure comprises at least a first limiting structure defining a first interior space; a transducer proximal to the first interior space; and a first synthetic polymer capable of selectively binding a first analyte, within the confinement structure. The confinement structure may have a second or further limiting structure defining a second or further interior space containing the first or preceding interior space. The sensor may also have additional confinement structures containing different materials for detecting additional analytes or taking reference measurements.

Abstract translation: 本发明涉及适于检测一种或多种分析物的存在的传感器。 传感器包括基板; 限制结构，其设置在所述基板上，其中所述约束结构包括限定第一内部空间的至少第一限制结构; 靠近所述第一内部空间的换能器; 以及能够在限制结构内选择性地结合第一分析物的第一合成聚合物。 限制结构可以具有限定包含第一或前一内部空间的第二或另外的内部空间的第二或另外的限制结构。 传感器还可以具有包含用于检测附加分析物或进行参考测量的不同材料的附加限制结构。

公开(公告)号：US20060166407A1

公开(公告)日：2006-07-27

申请号：US10523528

申请日：2003-09-01

Applicant: Tej Kaushal ,  Paul Manning ,  John Gillham ,  Gary Stacey ,  David Pooley ,  Peter Laitenberger

Inventor： Tej Kaushal ,  Paul Manning ,  John Gillham ,  Gary Stacey ,  David Pooley ,  Peter Laitenberger

IPC: H01L21/50 ,  H01L21/48 ,  H01L21/44

CPC classification number: B81B7/0041 ,  G01J5/02 ,  G01J5/0285 ,  G01J5/04 ,  G01J5/045 ,  G01J5/08 ,  G01J5/0806 ,  G02B6/4201 ,  G02B6/4204 ,  G02B6/4251 ,  H01L21/50 ,  H01L23/10 ,  H01L2224/48091 ,  H01L2924/01322 ,  H01L2924/00014 ,  H01L2924/00

Abstract: A method of hermetically packaging an electronic device (8), in an enclosure (2) comprising mutually inter-engageable first and second housing members (4, 6), comprising the steps of securing the electronic device (8) to the first housing member (4), engaging the first (4) and second (6) housing members such that an hermetic seal is provided there between, wherein the engagement step is performed in a controlled atmosphere. The hermetic seal may be provided by an interference fit between the first (4) and second (6) housing members or via sealing means (16) interposed between the housing members (4, 6). The second housing member (6) may comprise an optical element (20), for example a window or lens. The packaging method is particularly applicable to packaging thermal detectors, for example microbolometer arrays.

Abstract translation: 一种在包括相互可互相接合的第一和第二壳体构件（4,6）的外壳（2）中气密地包装电子设备（8）的方法，包括以下步骤：将所述电子设备（8）固定到所述第一壳体构件 （4），接合所述第一（4）和第二（6）壳体构件，使得在其间设置气密密封，其中所述接合步骤在受控的气氛中进行。 气密密封件可以通过第一（4）和第二（6）壳体构件之间的过盈配合或者插入在壳体构件（4,6）之间的密封装置（16）来提供。 第二壳体构件（6）可以包括光学元件（20），例如窗口或透镜。 包装方法特别适用于包装热检测器，例如微电热计阵列。

公开(公告)号：US08591105B2

公开(公告)日：2013-11-26

申请号：US11910120

申请日：2006-04-03

Applicant: Jürgen-Michael Weick ,  Armin Horn ,  Gerhard Hammann ,  Peter Laitenberger ,  Nick Collier ,  Ross Peter Jones

Inventor： Jürgen-Michael Weick ,  Armin Horn ,  Gerhard Hammann ,  Peter Laitenberger ,  Nick Collier ,  Ross Peter Jones

IPC: G01K7/01 ,  G01J5/08 ,  G01J5/10 ,  G02B6/02 ,  H01L27/00

CPC classification number: H01L27/146 ,  B23K26/702 ,  G01K17/003

Abstract: The invention relates to an optical element for guiding and forming a laser beam, and to a method for recording beam parameters, particularly in a laser system, comprising a carrier substrate (40) and a coating (39), which is applied to at least one side of the carrier substrate (40), and comprising at least one temperature sensor (38). The temperature sensor (38) is comprised of a number of pixels arranged in a matrix, and each respective pixel has at least one temperature-sensitive element (39). The at least one temperature-sensitive element (39) of the pixel is constructed inside the carrier substrate (40) made of silicon.

Abstract translation: 本发明涉及一种用于引导和形成激光束的光学元件，以及用于记录光束参数的方法，特别是在激光系统中，包括载体基底（40）和涂层（39），至少应用于 载体基板（40）的一侧，并且包括至少一个温度传感器（38）。 温度传感器（38）由排列成矩阵的多个像素组成，并且各个像素具有至少一个温度敏感元件（39）。 像素的至少一个温度敏感元件（39）被构造在由硅制成的载体衬底（40）的内部。

公开(公告)号：US20110120206A1

公开(公告)日：2011-05-26

申请号：US12918311

申请日：2009-02-19

Applicant: Gavin Troughton ,  Peter Laitenberger

Inventor： Gavin Troughton ,  Peter Laitenberger

IPC: G01N33/00

CPC classification number: A61B5/1495 ,  A61B2560/0223

Abstract: The present application discloses a number of methods of calibrating a sensor for measuring an analyte in a patient monitoring system. In a first embodiment, the method comprises calculating a sensor drift; calibrating the sensor using at least one calibration fluid; and periodically updating the sensor calibration based on the sensor drift calculation. In a second embodiment, the system comprises means for adjusting a gas concentration in a fluid, and the method comprises providing a calibration fluid; setting the analyte concentration in the first fluid to a first concentration with said adjusting means; measuring the first analyte concentration with the sensor; setting the analyte concentration in the first fluid to a second concentration with said adjusting means; measuring the second analyte concentration with the sensor; and determining the calibration coefficients for the sensor from the measured first analyte concentration and the measured second analyte concentration. In a third embodiment, the method comprises exposing the sensor to a first fluid comprising a first unknown concentration of the analyte; measuring the first unknown analyte concentration with the sensor; determining the first unknown analyte concentration with an analyser external to the patient monitoring system; providing the sensor with the determined first analyte concentration, and determining the calibration coefficients for the sensor from the measured first unknown analyte concentration and the analyte concentration determined by the analyser. At least some of the above embodiments ensure that the period between recalibrations of the sensor is extended, thus reducing the number of disruptions to the sensor monitoring process.

Abstract translation: 本申请公开了一些校准用于测量患者监测系统中的分析物的传感器的方法。 在第一实施例中，该方法包括计算传感器漂移; 使用至少一个校准流体校准传感器; 并基于传感器漂移计算周期性地更新传感器校准。 在第二实施例中，系统包括用于调节流体中的气体浓度的装置，并且该方法包括提供校准流体; 将所述第一流体中的分析物浓度用所述调节装置设定为第一浓度; 用传感器测量第一分析物浓度; 将所述第一流体中的分析物浓度用所述调节装置设定为第二浓度; 用传感器测量第二分析物浓度; 以及根据测量的第一分析物浓度和测量的第二分析物浓度确定传感器的校准系数。 在第三实施例中，该方法包括将传感器暴露于包含分析物的第一未知浓度的第一流体; 用传感器测量第一个未知分析物浓度; 使用患者监测系统外部的分析仪确定第一未知分析物浓度; 向传感器提供确定的第一分析物浓度，以及根据测量的第一未知分析物浓度和由分析仪确定的分析物浓度确定传感器的校准系数。 上述实施例中的至少一些确保传感器的重新校准之间的周期延长，从而减少传感器监测过程的中断次数。

公开(公告)号：US20100296546A1

公开(公告)日：2010-11-25

申请号：US11910120

申请日：2006-04-03

Applicant: Jürgen-Michael Weick ,  Armin Horn ,  Gerhard Hammann ,  Peter Laitenberger ,  Nick Collier ,  Ross Peter Jones

Inventor： Jürgen-Michael Weick ,  Armin Horn ,  Gerhard Hammann ,  Peter Laitenberger ,  Nick Collier ,  Ross Peter Jones

IPC: G01K13/00 ,  G02B27/09 ,  G02B7/192

CPC classification number: H01L27/146 ,  B23K26/702 ,  G01K17/003

Abstract: The invention relates to an optical element for guiding and forming a laser beam, and to a method for recording beam parameters, particularly in a laser system, comprising a carrier substrate (40) and a coating (39), which is applied to at least one side of the carrier substrate (40), and comprising at least one temperature sensor (38). The temperature sensor (38) is comprised of a number of pixels arranged in a matrix, and each respective pixel has at least one temperature-sensitive element (39). The at least one temperature-sensitive element (39) of the pixel is constructed inside the carrier substrate (40) made of silicon.

Abstract translation: 本发明涉及一种用于引导和形成激光束的光学元件，以及用于记录光束参数的方法，特别是在激光系统中，包括载体基底（40）和涂层（39），至少应用于 载体基板（40）的一侧，并且包括至少一个温度传感器（38）。 温度传感器（38）由排列成矩阵的多个像素组成，并且各个像素具有至少一个温度敏感元件（39）。 像素的至少一个温度敏感元件（39）被构造在由硅制成的载体衬底（40）的内部。