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1.发明申请METHOD AND MICROSYSTEM FOR DETECTING ANALYTES WHICH ARE PRESENT IN DROPS OF LIQUID 有权用于检测液体液体中分析物的方法和微结构公开(公告)号：US20140008224A1
公开(公告)日：2014-01-09
申请号：US13984964
申请日：2011-02-11
Applicant: Vincent Agache , Patrice Caillat , Pierre Puget
Inventor： Vincent Agache , Patrice Caillat , Pierre Puget
IPC: B03C5/00
CPC classification number: B03C5/005 , B03C5/026 , B03C2201/26
Abstract: A detection method of detecting analytes of interest which are present in a liquid. The detection method including the steps of forming drops of liquid on a first surface by capillary breaking of a finger of liquid, which is initially formed by liquid dielectrophoresis. The thus formed drops each come into contact with a different detection surface, which is arranged facing the first surface. Analytes of interest which are present in each of the drops are detected at the corresponding detection surface.
Abstract translation: 检测存在于液体中的感兴趣的分析物的检测方法。 检测方法包括以下步骤：通过最初通过液体介电电泳形成的液体手指的毛细管断裂在第一表面上形成液滴。 这样形成的液滴各自与面对第一表面布置的不同检测表面接触。 每个液滴中存在的感兴趣的分析物在相应的检测表面被检测。
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公开(公告)号：US20110108424A1
公开(公告)日：2011-05-12
申请号：US12991548
申请日：2009-05-05
Applicant: Pierre Puget , Florence Ricoul
Inventor： Pierre Puget , Florence Ricoul
CPC classification number: G01N27/44791 , B01J20/205 , B01J20/28007 , B01L3/502707 , B01L3/502753 , B01L2300/0816 , B01L2300/0896 , B01L2400/0415 , B01L2400/086 , B82Y30/00
Abstract: The device for separating biomolecules from a fluid comprises a microfluidic component provided with at least one microchannel having at least one of the walls supporting a plurality of nanotubes or nanowires. The component comprises at least one electrode electrically connected to at least a part of the nanotubes or nanowires and the device comprises means for applying a voltage between the electrode and the fluid. The nanotubes or nanowires are divided into several active areas in which the nanotubes or nanowires have a different density.
Abstract translation: 用于从流体分离生物分子的装置包括提供有至少一个微通道的微流体组件，其具有支撑多个纳米管或纳米线的至少一个壁。 该组件包括电连接到纳米管或纳米线的至少一部分的至少一个电极，并且该装置包括用于在电极和流体之间施加电压的装置。 纳米管或纳米线被分成若干活性区域，其中纳米管或纳米线具有不同的密度。
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公开(公告)号：US10048234B2
公开(公告)日：2018-08-14
申请号：US14405000
申请日：2012-06-04
Applicant: Phillipe Andreucci , Eric Colinet , Philippe Coric , Jean-Claude De Wit , Pierre Puget
Inventor： Phillipe Andreucci , Eric Colinet , Philippe Coric , Jean-Claude De Wit , Pierre Puget
Abstract: Analyzer 1 for analyzing a fluid 3 containing at least one substance to be analyzed and at least one inflammable substance containing: a source of gas 9 to provide a flux of diluent gas, an injecting nozzle 11 for introducing samples of the fluid into the flux of diluent gas and for producing a gaseous flux, and a detector 7 for analyzing the gaseous flux, wherein: the source of gas is intended to deliver a flux of diluent gas containing a material capable of supporting the combustion of the inflammable substance, preferably to deliver a flux of air, the injection nozzle is configured so as to introduce into the diluent gas samples of the fluid such that the average volume fraction of the fluid in the gaseous flux is less than 1/2,000 and preferably less than 1/20,000, and the detector contains at least one microsensor for detecting the substance to be analyzed. Corresponding method.
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公开(公告)号：US20130125621A1
公开(公告)日：2013-05-23
申请号：US13702727
申请日：2011-06-06
Applicant: Pierre Puget , Edward B. Myers , Michael L. Roukes
Inventor： Pierre Puget , Edward B. Myers , Michael L. Roukes
IPC: G01N30/78
CPC classification number: G01N30/78 , G01N30/463 , G01N30/60 , G01N30/6039 , G01N30/6052 , G01N30/6095 , G01N30/8693
Abstract: A system for analyzing a gas mixture, including at least one chromatography column, a mechanism injecting the mixture into the column, and a mechanism detecting compound(s) forming the gas mixture, the detection mechanism including at least one detector of nanosensor type of an outlet of the column and a detector of nanosensor type in the column, capable of detecting passage of the compounds. It is then possible to determine the velocity of each of the compounds within the system.
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5.发明授权System for analyzing a gas mixture including at least one chromatography column 有权用于分析包含至少一个色谱柱的气体混合物的系统公开(公告)号：US08820140B2
公开(公告)日：2014-09-02
申请号：US13702727
申请日：2011-06-06
Applicant: Pierre Puget , Edward B. Myers , Michael L. Roukes
Inventor： Pierre Puget , Edward B. Myers , Michael L. Roukes
IPC: G01N30/78
CPC classification number: G01N30/78 , G01N30/463 , G01N30/60 , G01N30/6039 , G01N30/6052 , G01N30/6095 , G01N30/8693
Abstract: A system for analyzing a gas mixture, including at least one chromatography column, a mechanism injecting the mixture into the column, and a mechanism detecting compound(s) forming the gas mixture, the detection mechanism including at least one detector of nanosensor type of an outlet of the column and a detector of nanosensor type in the column, capable of detecting passage of the compounds. It is then possible to determine the velocity of each of the compounds within the system.
Abstract translation: 一种用于分析气体混合物的系统，包括至少一个层析柱，将混合物注入柱中的机理以及形成气体混合物的机理检测化合物，所述检测机构包括至少一个纳米传感器类型的检测器 柱的出口和柱中的纳米传感器类型的检测器，能够检测化合物的通过。 然后可以确定系统内每种化合物的速度。
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Patent Agency Ranking
公开(公告)号：US09901934B2
公开(公告)日：2018-02-27
申请号：US13984964
申请日：2011-02-11
Applicant: Vincent Agache , Patrice Caillat , Pierre Puget
Inventor： Vincent Agache , Patrice Caillat , Pierre Puget
CPC classification number: B03C5/005 , B03C5/026 , B03C2201/26
Abstract: A detection method of detecting analytes of interest which are present in a liquid. The detection method including the steps of forming drops of liquid on a first surface by capillary breaking of a finger of liquid, which is initially formed by liquid dielectrophoresis. The thus formed drops each come into contact with a different detection surface, which is arranged facing the first surface. Analytes of interest which are present in each of the drops are detected at the corresponding detection surface.
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公开(公告)号：US08202496B2
公开(公告)日：2012-06-19
申请号：US12379468
申请日：2009-02-23
Applicant: Jean-Christophe Coiffic , Frédéric-Xavier Gaillard , Pierre Puget
Inventor： Jean-Christophe Coiffic , Frédéric-Xavier Gaillard , Pierre Puget
CPC classification number: B01D61/28 , B01L3/502753 , Y10S977/70 , Y10S977/701 , Y10S977/707 , Y10S977/781 , Y10S977/782 , Y10S977/809 , Y10S977/811 , Y10S977/842
Abstract: A molecule is separated from a liquid sample containing said molecule and at least one additional molecule having a larger hydrodynamic diameter than the hydrodynamic diameter of the molecule to be separated, by means of a separation device comprising a substrate, at least one circulation channel arranged in said substrate, and at least one nanotube associated with said molecule to be separated and formed on a free surface of the substrate. Separation is achieved by means of the internal channel of a nanotube, such as a carbon nanotube, presenting an effective diameter chosen in predetermined and controlled manner. The effective diameter of the internal channel is chosen such as to be larger than the hydrodynamic diameter of the molecule to be separated and smaller than the hydrodynamic diameter of the additional molecules of larger hydrodynamic diameters.
Abstract translation: 通过包括基底的分离装置将分子从含有所述分子的液体样品和至少一个具有比要分离的分子的流体动力学直径更大的流体动力学直径的另外的分子分离，至少一个循环通道被布置在 所述基底和至少一个与所述待分离的分子缔合的纳米管，所述分子被形成在所述基底的自由表面上。 通过纳米管的内部通道（例如碳纳米管）实现分离，其具有以预定和受控的方式选择的有效直径。 内部通道的有效直径选择为大于要分离的分子的流体动力学直径，并且小于较大流体动力学直径的附加分子的流体动力学直径。
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8.发明申请公开(公告)号：US20150300996A1
公开(公告)日：2015-10-22
申请号：US14405000
申请日：2012-06-04
Applicant: Phillipe Andreucci , Eric Colinet , Philippe Coric , Jean-Claude De Wit , Pierre Puget
Inventor： Phillipe Andreucci , Eric Colinet , Philippe Coric , Jean-Claude De Wit , Pierre Puget
CPC classification number: G01N30/16 , G01N33/22 , G01N33/225
Abstract: Analyzer 1 for analyzing a fluid 3 containing at least one substance to be analyzed and at least one inflammable substance containing: a source of gas 9 to provide a flux of diluent gas, an injecting nozzle 11 for introducing samples of the fluid into the flux of diluent gas and for producing a gaseous flux, and a detector 7 for analyzing the gaseous flux, wherein: the source of gas is intended to deliver a flux of diluent gas containing a material capable of supporting the combustion of the inflammable substance, preferably to deliver a flux of air, the injection nozzle is configured so as to introduce into the diluent gas samples of the fluid such that the average volume fraction of the fluid in the gaseous flux is less than 1/2,000 and preferably less than 1/20,000, and the detector contains at least one microsensor for detecting the substance to be analyzed. Corresponding method.
Abstract translation: 用于分析含有至少一种待分析物质的流体3的分析器1和至少一种易燃物质，其包含：提供稀释气体助熔剂的气体源9;用于将流体样品引入到 稀释气体和用于产生气体流量的检测器7，用于分析气体流量的检测器7，其中：气体源旨在输送含有能够支持易燃物质燃烧的材料的稀释气体流，优选地输送 空气通量，注射喷嘴被配置成引入流体的稀释气体样本，使得气体流量中的流体的平均体积分数小于1 / 2,000，优选小于1 / 20,000，以及 检测器包含至少一个用于检测待分析物质的微传感器。 相应的方法
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9.发明申请公开(公告)号：US20120171682A1
公开(公告)日：2012-07-05
申请号：US13255387
申请日：2010-03-08
Applicant: Gilles Marchand , Dorothee Jary , Pierre Puget , Francois Tardif
Inventor： Gilles Marchand , Dorothee Jary , Pierre Puget , Francois Tardif
CPC classification number: C12Q1/6844 , C12Q2563/185 , C12Q2563/155
Abstract: The present invention relates to a method and a kit for detecting, optionally identifying and optionally quantifying at least one carbon nanotube possibly included in a sample, including the steps consisting in: (a) subjecting said sample to conditions enabling the amplification of a nucleotide sequence using primers capable of amplifying said nucleotide sequence, the possibly included carbon nanotube having been functionalized by said nucleotide sequence prior to step (a), and (b) detecting, optionally identifying and optionally quantifying the amplification product possibly obtained after step (a).
Abstract translation: 本发明涉及用于检测任选地鉴定和任选定量可能包含在样品中的至少一种碳纳米管的方法和试剂盒，其包括以下步骤：（a）使所述样品经受能够扩增核苷酸序列的条件 使用能够扩增所述核苷酸序列的引物，可能包括的在步骤（a）之前由所述核苷酸序列官能化的碳纳米管，和（b）检测任选地鉴定和任选定量可能在步骤（a）之后获得的扩增产物。
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公开(公告)号：US20090218226A1
公开(公告)日：2009-09-03
申请号：US12379468
申请日：2009-02-23
Applicant: Jean-Christophe Coiffic , Frederic-Xavier Gaillard , Pierre Puget
Inventor： Jean-Christophe Coiffic , Frederic-Xavier Gaillard , Pierre Puget
CPC classification number: B01D61/28 , B01L3/502753 , Y10S977/70 , Y10S977/701 , Y10S977/707 , Y10S977/781 , Y10S977/782 , Y10S977/809 , Y10S977/811 , Y10S977/842
Abstract: Separation device of molecules and production method thereof. A molecule is separated from a liquid sample containing said molecule and at least one additional molecule having a larger hydrodynamic diameter than the hydrodynamic diameter of the molecule to be separated, by means of a separation device comprising a substrate, at least one circulation channel arranged in said substrate, and at least one nanotube associated with said molecule to be separated and formed on a free surface of the substrate. Separation is achieved by means of the internal channel of a nanotube, such as a carbon nanotube, presenting an effective diameter chosen in predetermined and controlled manner. The effective diameter of the internal channel is chosen such as to be larger than the hydrodynamic diameter of the molecule to be separated and smaller than the hydrodynamic diameter of the additional molecules of larger hydrodynamic diameters.
Abstract translation: 分子分离装置及其制备方法。 通过包括基底的分离装置将分子从含有所述分子的液体样品和至少一个具有比要分离的分子的流体动力学直径更大的流体动力学直径的另外的分子分离，至少一个循环通道被布置在 所述基底和至少一个与所述待分离的分子缔合的纳米管，所述分子被形成在所述基底的自由表面上。 通过纳米管的内部通道（例如碳纳米管）实现分离，其具有以预定和受控的方式选择的有效直径。 内部通道的有效直径选择为大于要分离的分子的流体动力学直径，并且小于较大流体动力学直径的附加分子的流体动力学直径。
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