Multifunctional polymeric surface coatings in analytic and sensor devices
    3.
    发明授权
    Multifunctional polymeric surface coatings in analytic and sensor devices 有权
    分析和传感器设备中的多功能聚合物表面涂层

    公开(公告)号:US06884628B2

    公开(公告)日:2005-04-26

    申请号:US09560472

    申请日:2000-04-28

    摘要: Multifunctional, polyionic copolymers with molecular architectures and properties optimized for specific applications are synthesized on/or applied to substrate surfaces for analytical and sensing purposes. The coatings are particularly useful for suppression of non-specific interaction, adsorption or attachment of molecular or ionic components present in an analyte solution. Chemical, biochemical or biological groups that are able to recognize, interact with and bind specifically to target molecules in the material containing the analyte to be detected can be coupled to, integrated into, or absorbed to the multifunctional copolymers. These multifunctional copolymer coatings are compatible with a variety of different established methods to detect, sense and quantify the target molecule in an analyte. The multifunctional copolymer coatings typically include brush copolymers based on a polycationic or polyanionic (jointly referred to herein as ‘polyionic’) backbone with side chains that control interaction with the environment, such as poly(ethylene glycol) or poly(ethylene oxide)-based side chains that decrease cellular adhesion, and analyte-specific side chains. They can be used to pattern the surfaces into non-adhesive and specifically adhesive areas by applications of known techniques such as microfluidic or contact printing techniques.

    摘要翻译: 具有分子结构和针对特定应用优化的性能的多功能聚异戊二烯共聚物在/或应用于基材表面进行合成,用于分析和感测目的。 涂层对于抑制分析物溶液中存在的分子或离子组分的非特异性相互作用,吸附或附着是特别有用的。 能够识别,相互作用并且特异性结合含有待检测分析物的物质中的靶分子的化学,生物化学或生物学基团可与多功能共聚物偶联,整合或吸收。 这些多功能共聚物涂层与各种不同的已知方法兼容,以检测,感测和定量分析物中的目标分子。 多功能共聚物涂层通常包括基于聚阳离子或聚阴离子(共同称为“聚阴离子”)骨架的刷共聚物,侧链具有控制与环境相互作用的侧链,例如聚(乙二醇)或聚(环氧乙烷) 减少细胞粘附的侧链和分析物特异性侧链。 它们可用于通过已知技术如微流体或接触印刷技术的应用将表面图案化成非粘合性和特异性粘合剂区域。

    Melt spinnable copolyamines with improved modulus of elasticity,
filaments produced from them and use of such filaments
    6.
    发明授权
    Melt spinnable copolyamines with improved modulus of elasticity, filaments produced from them and use of such filaments 失效
    具有改善的弹性模量的熔融可纺共聚酰胺,由它们生产的长丝和这种长丝的使用

    公开(公告)号:US5698660A

    公开(公告)日:1997-12-16

    申请号:US649581

    申请日:1996-05-28

    摘要: A copolyamide with an improved modulus of elasticity for the melt-spinning of filaments consists of at least 75 wt. % of a linear polyamide base polymer with a melting point of 150.degree.-320.degree. C. and at least 0.5 wt. % of a block comonomer which is incorporated into the base polymer and has a glass transition temperature (T.sub.g) between 130.degree. and 330.degree. C. and a degree of polymerization (DP) of

    摘要翻译: PCT No.PCT / CH95 / 00207 Sec。 371日期:1996年5月28日 102(e)日期1996年5月28日PCT提交1995年9月19日PCT公布。 公开号WO96 / 10597 日期1996年4月11日具有改善的长丝熔体纺丝的弹性模量的共聚酰胺由至少75wt。 %的熔点为150-320℃的线性聚酰胺基聚合物和至少0.5wt。 嵌入基础聚合物中的玻璃化转变温度(Tg)为130〜330℃,聚合度(DP)<100的嵌段共聚单体的%。 由初始模量为500至1500cN / tex的改性共聚物生产的长丝适用于生产技术织物。