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公开(公告)号：US4634576A
公开(公告)日：1987-01-06
申请号：US460916
申请日：1983-01-25
Applicant: Kevin Galle , Ryoichi Orimo , Masahiko Sakurada , Taiichi Banno , Sugio Manabe
Inventor： Kevin Galle , Ryoichi Orimo , Masahiko Sakurada , Taiichi Banno , Sugio Manabe
CPC classification number: G01N35/1002 , G01N35/02 , G01N2035/00435 , G01N2035/00752 , G01N2035/0465 , G01N2035/1025
Abstract: An automatic analyzing apparatus for effecting chemical analyses for various sample liquids such as blood, urine, and the like, comprising a sample delivery pump for metering a sample liquid into a reaction cuvette, a reagent delivery pump for delivering to the reaction cuvette a given amount of a given reagent selected from a plurality of reagents contained in a reagent cassette, to form a test liquid, a feed mechanism for successively supplying reaction cuvettes along a circular reaction line, a plurality of photometering sections arranged along the reaction line for effecting a plurality of photometric and/or nephelometric and/or fluorometric measurements for each test liquid at different time instances to produce a plurality of photometric results, and circuitry for receiving the photometric results and selecting therefrom given quantitative analytical data of a given test item.
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公开(公告)号：US4558946A
公开(公告)日：1985-12-17
申请号：US460913
申请日：1983-01-25
Applicant: Kevin Galle , Ryoichi Orimo , Masahiko Sakurada , Taiichi Banno , Sugio Manabe
Inventor： Kevin Galle , Ryoichi Orimo , Masahiko Sakurada , Taiichi Banno , Sugio Manabe
CPC classification number: G01N35/1002 , G01N35/02 , G01N2035/00435 , G01N2035/00752 , G01N2035/0465 , G01N2035/1025
Abstract: An automatic analyzing apparatus for effecting chemical analyses for various sample liquids such as blood, urine, and the like, comprising a sample delivery pump for metering a sample liquid into a reaction cuvette, a reagent delivery pump for delivering to the reaction cuvette a given amount of a given reagent selected from a plurality of reagents contained in a reagent cassette, to form a test liquid, a feed mechanism for successively supplying reaction cuvettes along a circular reaction line, a plurality of photometering sections arranged along the reaction line for effecting a plurality of photometric and/or nephelometric and/or fluorometric measurements for each test liquid at different time instances to produce a plurality of photometric results, and circuitry for receiving the photometric results and selecting therefrom given quantitative analytical data of a given test item.
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公开(公告)号：US4950077A
公开(公告)日：1990-08-21
申请号：US343681
申请日：1989-04-27
Applicant: Sugio Manabe
Inventor： Sugio Manabe
CPC classification number: G01N21/253 , G01J3/18 , G01J3/2803 , G01N2201/0407 , G01N2201/0415 , G01N2201/0826 , G01N2201/0833
Abstract: A photoelectric measuring apparatus for use in an automatic chemical analyzer in which a plurality of test items are analyzed by using light beams having different wavelengths, including a white light source for emitting a polychromatic light beam, a grating for diffracting the polychromatic light beam into a plurality of light beams having predetermined different wavelengths, a plurality of light guides for guiding the light beams emanating from the grating to a plurality of cuvettes containing test liquids to be analyzed, a plurality of light receiving elements for receiving light beams transmitted through the cuvettes, an additional light guide for guiding a polychromatic light beam emanating from the grating as the zero order light beam to a cuvette via an optical filter having a desired transmission wavelength, and an additional light receiving element for receiving a light beam transmitted through the cuvette.
Abstract translation: 一种用于自动化学分析仪的光电测量装置，其中通过使用具有不同波长的光束来分析多个测试项目，所述光束包括用于发射多色光束的白色光源，用于将多色光束衍射为 具有预定不同波长的多个光束，用于将从光栅发射的光束引导到包含待分析测试液体的多个比色杯的多个光导;多个用于接收透过比色杯的光束的光接收元件， 用于将通过具有期望的透射波长的滤光器将从光栅发出的多色光束作为零级光束引导到比色杯的附加光导，以及用于接收透射通过比色杯的光束的附加光接收元件。
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公开(公告)号：US4636360A
公开(公告)日：1987-01-13
申请号：US741840
申请日：1985-06-06
Applicant: Masahiko Sakurada , Sugio Manabe , Hideaki Okamura , Nagahiro Gocho
Inventor： Masahiko Sakurada , Sugio Manabe , Hideaki Okamura , Nagahiro Gocho
CPC classification number: G01N21/274 , Y10T436/113332
Abstract: An automatic analyzing apparatus for automatically effecting chemical analysis on a sample of blood, urea or the like dependent on measurement items by measuring the light absorption degree of a reaction liquid through a reaction vessel, comprising a reaction liquid photometric unit, a photometric unit independent of the reaction light photometric unit and operative to measure beforehand the light absorption degree of the reaction vessel per se or the reaction vessel containing a reagent or dilute liquid, and means for correcting the light absorption degree of the reaction liquid measured at the reaction liquid photometric unit on the basis of the light absorption degree of the reaction vessel per se or the light absorption degree of the reaction vessel containing the reagent or dilute liquid measured at the independent photometric unit.
Abstract translation: 一种自动分析装置，用于通过测量通过反应容器的反应液的光吸收度来自动对取决于测量项目的血液，尿素等样品进行化学分析，包括反应液体测光单元，独立于 所述反应光测光单元预先测量反应容器本身的光吸收度或含有试剂或稀液体的反应容器，以及用于校正在反应液体测光单元上测量的反应液的光吸收度的装置 基于反应容器本身的光吸收度或含有在独立测光单元测定的试剂或稀液体的反应容器的光吸收度。
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公开(公告)号：US4539296A
公开(公告)日：1985-09-03
申请号：US550507
申请日：1983-11-10
Applicant: Sugio Manabe
Inventor： Sugio Manabe
CPC classification number: G01N21/253 , G01N21/274 , Y10T436/11 , Y10T436/113332
Abstract: In a method of analyzing chemical substances in sample liquids, reagent blank absorbances with respect to a light amount transmitted through air or water are measured previously at a plurality of photometering positions and are stored in a memory. Then sample absorbances are measured at respective photometering positions and the reagent blank absorbances are substrated from the sample absorbances at the respective photometering positions, so that a required absorbance variation of the sample liquid with respect to time is calculated from the sample absorbances thus corrected. Therefore, even if a calibration curve linearity is not perfectly identical with each other at the respective photometering positions, it is possible to obtain accurate analyzing results.
Abstract translation: 在分析样品液体中的化学物质的方法中，先前在多个测光位置测量相对于通过空气或水透过的光量的试剂空白吸光度并存储在存储器中。 然后在相应的测光位置测量样品吸光度，并且将试剂空白吸光度从各个测光位置处的样品吸光度中减去，从而根据校正的样品吸光度计算样品液体相对于时间的所需吸光度变化。 因此，即使校准曲线的线性度在各自的测光位置上彼此不完全相同，也可以得到准确的分析结果。
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Patent Agency Ranking
公开(公告)号：US4311394A
公开(公告)日：1982-01-19
申请号：US138518
申请日：1980-04-09
Applicant: Sugio Manabe
Inventor： Sugio Manabe
CPC classification number: G01N35/02 , G01N2035/0097 , G01N2035/0465 , G01N35/021 , G01N35/025
Abstract: An automatic analytical apparatus for effecting quantitative analysis of a given substance contained in a sample such as blood, urine or the like and comprising a sample holding and carrying means including a plurality of sample holding positions and operative to carry the sample held by one of the sample holding positions more than one round along a closed loop, a photometric means fitted to a given position of the closed loop and operative to effect at least two photometric operations, a transfer means for transferring one sample to the sample holding position without transferring any other sample to the latter, and a discarding means operative to discard the sample only which has been subjected to the given number of photometric operations.
Abstract translation: 一种自动分析装置，用于对包含在血液，尿液等样品中的给定物质进行定量分析，并且包括样品保持和携带装置，其包括多个样品保持位置，并且可操作以携带由 样品保持位置沿着闭环多于一个循环，光度测量装置装配到闭环的给定位置并用于实现至少两个测光操作;转移装置，用于将一个样品转移到样品保持位置而不转移任何其它 采样到后者，以及丢弃装置，其操作仅丢弃已经经过给定数量的测光操作的样品。
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7.发明申请ENDOSCOPIC THERAPEUTIC DEVICE, LIVING BODY TISSUE ANALYZING AND PROCESSING SYSTEM, AND SAMPLE-TAKING METHOD FOR TISSUE ANALYSIS PROCESS 审中-公开内窥镜治疗装置，生物体组织分析与处理系统及组织分析方法的取样方法公开(公告)号：US20080188767A1
公开(公告)日：2008-08-07
申请号：US12029897
申请日：2008-02-12
Applicant: Yoshinao OAKI , Sachiko KARAKI , Yutaka OTANI , Kiyotsugu KOJIMA , Tatsuya SAITO , Toshio NAKAMURA , Tsutomu ISHIGURO , Sugio MANABE , Koji TAKAMURA , Hiroko SAKAMOTO
Inventor： Yoshinao OAKI , Sachiko KARAKI , Yutaka OTANI , Kiyotsugu KOJIMA , Tatsuya SAITO , Toshio NAKAMURA , Tsutomu ISHIGURO , Sugio MANABE , Koji TAKAMURA , Hiroko SAKAMOTO
CPC classification number: A61B1/018 , A61B10/0096 , A61B10/0283 , A61B10/04 , A61B17/3403 , A61B17/3478 , A61B2010/045
Abstract: An endoscopic therapeutic device includes an elongated insertion section which is inserted into a living body through a therapeutic device channel of an endoscope, a tubular puncture needle which is disposed at a distal end portion of the insertion section and is made to pierce a living body tissue, a syringe for sampling the living body tissue in a state in which the puncture needle pierces the living body tissue, and a freezing device for subjecting the living body tissue, which is collected by the syringe, to a process for analysis.
Abstract translation: 内窥镜治疗装置包括：细长插入部，其通过内窥镜的治疗装置通道插入生物体;管状穿刺针，其设置在所述插入部的前端部，并且穿刺所述生物体组织 用于在穿刺针穿刺生物体组织的状态下取样生物体组织的注射器，以及将由注射器收集的生物体组织进行分析处理的冷冻装置。
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8.发明授权
公开(公告)号：US4971913A
公开(公告)日：1990-11-20
申请号：US139082
申请日：1987-12-23
Applicant: Sugio Manabe , Tauneaki Kadogaki
Inventor： Sugio Manabe , Tauneaki Kadogaki
IPC: G01N35/00
CPC classification number: G01N35/00 , Y10T436/114998 , Y10T436/115831 , Y10T436/12
Abstract: A multi-item automatic chemical analyzer comprising a reagent delivery system for delivering a plurality of reagents of different kinds into reaction vessels in succesion is disclosed. The influence of contamination between the reagents upon measurement is reduced or eliminated by controlling the reagent delivery system with a control system comprising a memory unit for storing information representing a relation of the test items, particularly the influence of contamination between the reagents upon the measurement, and a center process unit for controlling the operation of reagent delivery system in accordance with the stored information.
Abstract translation: 公开了一种多项自动化学分析仪，其包括用于将多种不同种类的试剂输送到反应容器中的试剂递送系统。 通过使用包括存储单元的控制系统控制试剂输送系统来减少或消除试剂之间的污染的影响，所述存储单元用于存储表示测试项目的关系的信息，特别是测量时试剂之间的污染的影响， 以及中央处理单元，用于根据所存储的信息控制试剂递送系统的操作。
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公开(公告)号：US4536369A
公开(公告)日：1985-08-20
申请号：US246055
申请日：1981-03-02
Applicant: Masahiko Sakurada , Sugio Manabe , Hideaki Okamura , Nagahiro Gocho
Inventor： Masahiko Sakurada , Sugio Manabe , Hideaki Okamura , Nagahiro Gocho
CPC classification number: G01N21/75 , G01N21/274 , Y10T436/113332
Abstract: An automatic analyzing apparatus for automatically effecting chemical analysis on a sample of blood, urea or the like dependent on measurement items by measuring the light absorption degree of a reaction liquid through a reaction vessel, comprising a reaction liquid photometric unit, a photometric unit independent of the reaction light photometric unit and operative to measure beforehand the light absorption degree of the reaction vessel per se or the reaction vessel containing a reagent or dilute liquid, and means for correcting the light absorption degree of the reaction liquid measured at the reaction liquid photometric unit on the basis of the light absorption degree of the reaction vessel per se or the light absorption degree of the reaction vessel containing the reagent or dilute liquid measured at the independent photometric unit.
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公开(公告)号：US4472505A
公开(公告)日：1984-09-18
申请号：US258549
申请日：1981-04-29
Applicant: Sugio Manabe , Taiichi Banno , Nagahiro Gocho , Masahiko Sakurada , Ryoichi Orimo
Inventor： Sugio Manabe , Taiichi Banno , Nagahiro Gocho , Masahiko Sakurada , Ryoichi Orimo
CPC classification number: G01N21/272 , G01N21/251 , Y10T436/113332
Abstract: A method of enhancing the accuracy and reliability of a chemical analysis, wherein a reaction is carried out by combining a sample liquid with at least one reagent to form a test liquid and the test liquid is photometrically scrutinized a plurality of times over an extended period of time to derive a number of photometric values. The derived values are then stored and a plurality of the stored photometric values are preliminarily selected from a given time frame, wherein the plurality of preliminarily selected values are less than a total number of stored photometric values. Successive preliminarily selected photometric values are compared with at least one predetermined standard to derive a comparison result and upon indication that useful data cannot be calculated from the preliminarily selected photometric values, a secondarily selecting step of selecting at least one photometric value from all of the stored photometric values, which were not preliminarily selected, is used to derive an analytical result which represents a concentration of a chemical substance in the test liquid or an activity of the test liquid.
Abstract translation: 一种提高化学分析的准确性和可靠性的方法，其中通过将样品液体与至少一种试剂组合以形成测试液体并且将测试液体在延长的时间段内多次光学测量来进行反应 时间推导出一些光度值。 然后存储导出值，并且从给定时间帧预先选择多个存储的测光值，其中多个预先选择的值小于存储的测光值的总数。 将连续的初步选择的光度值与至少一个预定标准进行比较以导出比较结果，并且在根据预先选择的测光值不能计算有用数据的指示时，从所有存储的所有光度值中选择至少一个测光值的二次选择步骤 未预先选择的光度值用于导出表示试验液体中的化学物质浓度或试验液体的活性的分析结果。
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