Protein Cleavage at Aspartic Acid Using Chemical Reagents
    1.
    发明申请
    Protein Cleavage at Aspartic Acid Using Chemical Reagents 审中-公开
    蛋白质裂解天冬氨酸使用化学试剂

    公开(公告)号:US20080318262A1

    公开(公告)日:2008-12-25

    申请号:US11575089

    申请日:2005-09-14

    IPC分类号: G01N33/68 C12Q1/48

    CPC分类号: G01N33/6848 C07K1/128

    摘要: The present invention relates to the methods of identifying and quantifying polypeptides in a given sample by mass spectrometric analysis. More specifically, the invention provides the methods for sample preparation for proteomic analysis: the methods for the fragmentation of proteins into peptides with the specific cleavage rule (cleavage at amino-terminal or carboxyl-terminal of aspartic acid), which are suitable for the analysis by mass spectrometry apparatus.

    摘要翻译: 本发明涉及通过质谱分析鉴定和定量给定样品中的多肽的方法。 更具体地,本发明提供了用于蛋白质组学分析的样品制备方法:将蛋白质分解为具有特异性裂解规则(天冬氨酸的氨基末端或羧基末端切割)的肽的方法,其适用于分析 通过质谱仪。

    ANGIOGENIC PEPTIDE
    3.
    发明申请
    ANGIOGENIC PEPTIDE 有权
    生殖肽

    公开(公告)号:US20110110875A1

    公开(公告)日:2011-05-12

    申请号:US12989065

    申请日:2009-04-23

    申请人: Taehoon Lee

    发明人: Taehoon Lee

    摘要: The present application discloses angiogenic peptides that cause intracellular calcium release in target cells and thereby induce proliferation, migration, and capillary-like tube formation in primary cultured endothelial cells. The angiogenic peptides can be used for preventing and/or treating angiognesis-related conditions, especially wound healing, treating foot and leg ulcers in a subject, etc. In addition, the angiogenic peptides can be used for cosmetics a constituent of cosmetics for aged skin, for examples, anti-wrinkle and skin whitening.

    摘要翻译: 本申请公开了导致细胞内钙释放的血管生成肽,从而诱导原代培养的内皮细胞中的增殖,迁移和毛细管样管形成。 血管生成肽可用于预防和/或治疗血管生成相关病症,特别是伤口愈合,治疗受试者的脚和腿部溃疡等。此外,血管生成肽可用于化妆品用于老化皮肤的化妆品的成分 例如,抗皱和皮肤美白。

    Angiogenic peptide
    7.
    发明授权

    公开(公告)号:US09925398B2

    公开(公告)日:2018-03-27

    申请号:US12989065

    申请日:2009-04-23

    申请人: Taehoon Lee

    发明人: Taehoon Lee

    摘要: The present application discloses angiogenic peptides that cause intracellular calcium release in target cells and thereby induce proliferation, migration, and capillary-like tube formation in primary cultured endothelial cells. The angiogenic peptides can be used for preventing and/or treating angiognesis-related conditions, especially wound healing, treating foot and leg ulcers in a subject, etc. In addition, the angiogenic peptides can be used for cosmetics a constituent of cosmetics for aged skin, for examples, anti-wrinkle and skin whitening.

    Mobile terminal and method for providing user interface thereof
    8.
    发明授权
    Mobile terminal and method for providing user interface thereof 有权
    移动终端及其用户界面的提供方法

    公开(公告)号:US09310996B2

    公开(公告)日:2016-04-12

    申请号:US13570060

    申请日:2012-08-08

    申请人: Taehoon Lee

    发明人: Taehoon Lee

    摘要: A mobile terminal including a wireless communication unit configured to wirelessly communicate with at least one other terminal; a display unit including a touch screen; a sensing unit configured to sense a touch input pattern on the display unit when the display unit is in a lock mode and displaying a lock screen; and a controller configured to detect at least a first code from the touch input pattern, said first code corresponding to at least a first portion of the touch input pattern, change the lock screen into a first screen on the display unit that is preset based on the detected first code, and release the lock mode with the first screen displayed when the sensing unit no longer senses the touch input pattern on the display unit.

    摘要翻译: 一种移动终端,包括被配置为与至少一个其他终端无线通信的无线通信单元; 包括触摸屏的显示单元; 感测单元,被配置为当所述显示单元处于锁定模式并且显示锁定屏幕时感测所述显示单元上的触摸输入图案; 以及控制器,被配置为从所述触摸输入图案中检测至少第一代码,所述第一代码对应于所述触摸输入图案的至少第一部分,将所述锁定屏幕改变为基于所述显示单元预设的第一屏幕 检测到的第一代码,并且当感测单元不再感测到显示单元上的触摸输入图案时,利用显示的第一屏幕释放锁定模式。

    MOBILE TERMINAL AND METHOD FOR PROVIDING USER INTERFACE THEREOF
    9.
    发明申请
    MOBILE TERMINAL AND METHOD FOR PROVIDING USER INTERFACE THEREOF 有权
    移动终端和提供用户界面的方法

    公开(公告)号:US20130088442A1

    公开(公告)日:2013-04-11

    申请号:US13570060

    申请日:2012-08-08

    申请人: Taehoon Lee

    发明人: Taehoon Lee

    IPC分类号: G06F3/041

    摘要: A mobile terminal including a wireless communication unit configured to wirelessly communicate with at least one other terminal; a display unit including a touch screen; a sensing unit configured to sense a touch input pattern on the display unit when the display unit is in a lock mode and displaying a lock screen; and a controller configured to detect at least a first code from the touch input pattern, said first code corresponding to at least a first portion of the touch input pattern, change the lock screen into a first screen on the display unit that is preset based on the detected first code, and release the lock mode with the first screen displayed when the sensing unit no longer senses the touch input pattern on the display unit.

    摘要翻译: 一种移动终端,包括配置成与至少一个其他终端无线通信的无线通信单元; 包括触摸屏的显示单元; 感测单元,被配置为当所述显示单元处于锁定模式并且显示锁定屏幕时感测所述显示单元上的触摸输入图案; 以及控制器,被配置为从所述触摸输入图案中检测至少第一代码,所述第一代码对应于所述触摸输入图案的至少第一部分,将所述锁定屏幕改变为基于所述显示单元预设的第一屏幕 检测到的第一代码,并且当感测单元不再感测到显示单元上的触摸输入图案时,利用显示的第一屏幕释放锁定模式。

    METHOD OF ANALYZING PROTEIN USING DATA-INDEPENDENT ANALYSIS COMBINED WITH DATA-DEPENDENT ANALYSIS
    10.
    发明申请
    METHOD OF ANALYZING PROTEIN USING DATA-INDEPENDENT ANALYSIS COMBINED WITH DATA-DEPENDENT ANALYSIS 审中-公开
    使用与数据依赖性分析相结合的独立分析数据分析蛋白质的方法

    公开(公告)号:US20120109533A1

    公开(公告)日:2012-05-03

    申请号:US13309038

    申请日:2011-12-01

    IPC分类号: G06F19/00

    摘要: The present invention relates to a method of analyzing a protein or proteins comprising the steps of: (A) pre-treating a mixture containing at least one protein to obtain peptides; (B) obtaining information about retention times and mass values of the obtained peptides by performing data-independent analysis; (C) searching a first database on the basis of the information obtained in step (B) to quantify and qualify a target protein or proteins; (D) extracting information about the quantified and qualified target protein or proteins; (E) obtaining information about retention times and mass values by performing data-dependent analysis from the extracted information of step (D); (F) searching a second database on the basis of the information obtained in step (E) to further quantify and qualify the target protein or proteins; and (G) comparing the search results of step (C) and (F) to verify the quantification and qualification.

    摘要翻译: 本发明涉及分析蛋白质或蛋白质的方法,包括以下步骤:(A)预处理含有至少一种蛋白质的混合物以获得肽; (B)通过进行数据无关分析获得获得的肽的保留时间和质量值的信息; (C)基于在步骤(B)中获得的信息来搜索第一数据库以定量和鉴定靶蛋白质; (D)提取关于定量和合格的靶蛋白或蛋白质的信息; (E)通过从所提取的步骤(D)的信息执行数据相关分析,获得关于保留时间和质量值的信息; (F)基于在步骤(E)中获得的信息来搜索第二数据库以进一步量化和鉴定目标蛋白质或蛋白质; 和(G)比较步骤(C)和(F)的搜索结果以验证量化和鉴定。