Abstract:
The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention is a siRNA comprising a sense RNA having a base sequence of contiguous 20 to 20 bases, preferably 23 to 27 bases, of ZFAT mRNA and an anti-sense RNA having a base sequence complementary to the base sequence of the sense RNA or a shRNA comprising a double-stranded RNA (dsRNA) with the sense RNA connected to the anti-sense RNA via a loop sequence.The inhibitory RNA for inhibiting the expression of ZFAT gene according to this invention decreases a rate of cell proliferation of cancer cells, etc., induces apoptosis of cells including cancer cells, or inhibits an immunoresponse by inhibiting the expression of the ZFAT gene. Therefore, the inhibitory RNA of this invention is useful for development of molecular target agents particularly for cancer cells or immunosuppressive agents.
Abstract:
A phase modulated signal receiver includes an operation part and a control part. An input power of a received light signal is measured based on current monitored by a monitor circuit. The operation part is configured to correct, on the basis of a ratio of the input power measured when a delay of a phase reference light output from a delay interferometer is a first delay and the input power when the delay of the phase reference light is a second delay, a value of the current monitored by the monitor circuit when the delay is the first delay to a corrected value that depends on the input power of the received light signal obtained when the delay is the first delay. The control part is configured to control the delay of the phase reference light of the delay interferometer by comparing the current monitored when the delay is the first delay and the corrected value of the current monitored when the delay is the second delay and maximizing or minimizing the current monitored by the monitor circuit.
Abstract:
The object is to provide an etching liquid for a conductive polymer having excellent etching capability toward a conductive polymer, and a method for patterning a conductive polymer employing the etching liquid for a conductive polymer. The conductive etching liquid of the present invention is selected from the group consisting of (1) an etching liquid comprising greater than 0.5 wt % but no greater than 70 wt % of (NH4)2Ce(NO3)8 or at least 0.5 wt % but no greater than 30 wt % of Ce(SO4)2, (2) an etching liquid comprising greater than 0.5 wt % but no greater than 30 wt % of (NH4)4Ce(SO4)4, (3) an etching liquid comprising a hypochlorous acid salt aqueous solution having an effective chlorine concentration of at least 0.06 wt % and a pH of greater than 3 but less than 8, (4) an etching liquid comprising nitrosyl chloride which comprises at least 5 wt % of hydrochloric acid and at least 20 wt % of nitric acid, a (hydrochloric acid concentration+0.51×nitric acid concentration) value being no greater than 35 wt %, and a (hydrochloric acid concentration+0.5×nitric acid concentration) value being at least 30 wt %, (5) an etching liquid comprising at least 3 wt % but no greater than 40 wt % of a bromic acid compound and at least 4 wt % of an inorganic acid, (6) an etching liquid comprising at least 6 wt % but no greater than 40 wt % of a chloric acid compound and at least 7 wt % of a hydrogen halide, (7) an etching liquid comprising at least 0.001 wt % but no greater than 20 wt % of a permanganic acid compound, and (8) an etching liquid comprising at least 3 wt % but no greater than 30 wt % of a hexavalent chromium compound.
Abstract:
An optical transmitter includes a laser diode drive circuit for driving a laser diode in accordance with a laser diode current that superimposes a pilot signal on a “0” logic level and a “1” logic level of a transmission signal, the pilot signal having a low-frequency compared with the transmission signal, so as to become an opposite phase each other, a monitor circuit for monitoring an optical output of the laser diode, a filter circuit for extracting a low-frequency component of the pilot signal from an output of the monitor circuit, a phase compare circuit for comparing a phase of the low-frequency component of the pilot signal extracted by the filter circuit with a phase of the pilot signal, and a deterioration judgment circuit for judging whether or not the laser diode deteriorates in accordance with a comparison result of the phase compare circuit.
Abstract:
An apparatus for controlling an extinction ratio of a light-emitting device, includes: a temperature detecting unit that detects a temperature of the device; a power detecting unit that detects an optical output power of the device; a modulation-current detecting unit that detects a modulation current input into the device; a POW computing unit that computes a power control value for the device based on the temperature; and an ER computing unit that computes an extinction ratio control value for the device based on the power control value, the optical output power, and the modulation current.
Abstract:
A disc brake for railway vehicles includes a brake disc fixed to a wheel or an axle of a railway vehicle and a brake lining configured to be pressed against a frictional surface of the brake disc by a brake caliper. The brake lining includes a plurality of friction members arranged to be spaced from each other, each of the friction members having a surface that faces the frictional surface of the brake disc, a metallic backing secured to back surfaces of the friction members, and a base plate supporting the friction members on the back surface side via spring members. The base plate is mounted to a brake caliper; wherein the friction members are provided in pairs with each pair being formed by two adjacent ones of the friction members, and the metallic backing is a one-piece member provided for each pair of the friction members.
Abstract:
A double rate processing part generates, at a double rate, a non-interlaced image signal every frame to twice generate a double-rate non-interlaced signal which has identical information duplicately. An interlace part, after a predetermined process is carried out on the double-rate non-interlaced signal twice generated by the double rate processing part, extracts an odd scan lines from one of the twice generated double-rate non-interlaced signal to generate an odd scan line image signal, extracts an even scan lines from the other of the twice generated double-rate non-interlaced signal to generate an even scan line image signal, so as to obtain an interlaced image signal for one frame.
Abstract:
An optical receiving apparatus, including an optical interferometer including first and second optical waveguides having light paths different in length and converting a phase modulated signal received by the optical receiving apparatus into an intensity modulated signal, monitors the results of the detecting by the temperature detector and the measuring by the electric current measure while sweeping the temperature of the first optical waveguide in a predetermined range; selects the temperature of the first optical waveguide at which temperature the average photocurrent has an extreme value based on the result of the monitoring; and varies the temperature of the first optical waveguide to the selected temperature.
Abstract:
An optical transceiver stores an output A/D value which is A/D-converted from reference voltage in an EEPROM as correction data in preparing the optical transceiver. The optical transceiver, receiving a request for outputting a monitored value from an external device connected therewith, calculates a variation based on difference between the output A/D value which is A/D-converted from the reference voltage at the timing when the request for outputting the monitored value is received and the correction data stored in the EEPROM. Then, the optical transceiver uses the calculated variation to convert current of light-input power which is input thereinto into voltage, amplify the voltage, and A/D-convert the voltage to thereby correct the output A/D value. The optical transceiver outputs the corrected A/D value to the connected external device as the monitored value.