METHOD TO IDENTIFY POLYPEPTIDE TOLL-LIKE RECEPTOR (TLR) LIGANDS
    1.
    发明申请
    METHOD TO IDENTIFY POLYPEPTIDE TOLL-LIKE RECEPTOR (TLR) LIGANDS 审中-公开
    识别多肽类似受体(TLR)配体的方法

    公开(公告)号:US20090068224A1

    公开(公告)日:2009-03-12

    申请号:US11815095

    申请日:2006-01-26

    CPC分类号: G01N33/566 G01N2333/705

    摘要: The present invention provides novel methods to identify polypeptide ligands for Toll-like Receptors (TLRs), such as TLR2, TLR4 and TLR5. The method involves the use of phage display technology in an iterative biopanning procedure. The invention also provides polypeptide TLR ligands identified by the methods of the invention. In preferred embodiments, the polypeptide TLR ligands so identified modulate TLR signaling and thereby regulate the Innate Immune Response. The invention also provides vaccines comprising a polypeptide TLR ligand identified by the methods of the invention and an antigen. The invention also provides methods of modulating TLR signaling using the polypeptide TLR ligands and vaccines of the invention.

    摘要翻译: 本发明提供鉴定Toll样受体(TLR)如TLR2,TLR4和TLR5的多肽配体的新方法。 该方法涉及在迭代生物淘选程序中使用噬菌体展示技术。 本发明还提供了通过本发明的方法鉴定的多肽TLR配体。 在优选的实施方案中,如此鉴定的多肽TLR配体调节TLR信号传导,从而调节先天免疫应答。 本发明还提供了包含通过本发明的方法鉴定的多肽TLR配体和抗原的疫苗。 本发明还提供了使用本发明的多肽TLR配体和疫苗调节TLR信号传导的方法。

    Electrode heating with remediation agent
    2.
    发明申请
    Electrode heating with remediation agent 有权
    电极加热补救剂

    公开(公告)号:US20060110218A1

    公开(公告)日:2006-05-25

    申请号:US10995463

    申请日:2004-11-23

    IPC分类号: B09C1/06

    摘要: A remediation method and system is disclosed. A plurality of conductors is installed into the subsurface to introduce electrical current to produce heat in the subsurface. One or more agents are released into the subsurface to cause or accelerate the decomposition of one or more pre-existing halogenated organic compounds and release halogen ions, improving electrode performance.

    摘要翻译: 公开了一种补救方法和系统。 多个导体被安装到地下以引入电流以在地下产生热量。 将一种或多种试剂释放到地下以引起或加速一种或多种预先存在的卤化有机化合物的分解并释放卤素离子,从而改善电极性能。

    Habitat Mount For Wall Mounted Taxidermy Mannequin
    4.
    发明申请
    Habitat Mount For Wall Mounted Taxidermy Mannequin 有权
    人造山壁挂式的标本车模型

    公开(公告)号:US20100072339A1

    公开(公告)日:2010-03-25

    申请号:US12565272

    申请日:2009-09-23

    IPC分类号: A47F5/08 A01N1/00 A41G1/00

    摘要: A habitat mount for a wall mounted taxidermy mannequin includes a habitat piece having a three dimensional first side with the appearance of one or more natural elements and an opposing generally planar second side. A tab extends outwardly from and generally parallel to a plane defined by the second side of the habitat piece. The tab is sized and shaped to mount directly to a rear side of the wall mounted taxidermy mannequin.

    摘要翻译: 一种用于壁挂式标本车辆模型的栖息地座椅包括具有三维第一侧的栖息部,其具有一个或多个天然元件的外观和相对的大致平坦的第二侧。 一个突出部从大致平行于由栖息地的第二面限定的平面向外延伸。 该标签的尺寸和形状可以直接安装在墙上安装的标本车模型的后侧。

    Dutch oven stand
    7.
    发明授权
    Dutch oven stand 失效
    荷兰烤箱架

    公开(公告)号:US06945243B1

    公开(公告)日:2005-09-20

    申请号:US10765408

    申请日:2004-01-27

    摘要: A portable Dutch Oven stand comprising a low aspect ratio and few parts which are integrally pieced together into one transportable unit. In a preferred form the Dutch Oven Stand includes a tray for holding cooking fuel (typically charcoal briquettes) at a safe distance from the ground while also maintaining such fuel from falling onto the ground, and while also supporting at least one Dutch Oven during cooking. The Dutch Oven stand also comprises folding legs permanently attached to the tray, a leveling means forming a part of the tray to level the stand prior to cooking, and a rotatable platform assembly for rotating a Dutch Oven while on the stand without lifting the Dutch Oven from the stand.

    摘要翻译: 便携式荷兰式烤箱架包括低纵横比和少数部件,它们整体拼接成一个可运输单元。 在一个优选的形式中,荷兰烤箱架包括用于将烹饪燃料(通常为木炭压块)放置在与地面安全距离的托盘,同时还保持这种燃料落入地面,同时还在烹饪期间至少支持一个荷兰烤箱。 荷兰烤箱支架还包括永久地附接到托盘的折叠腿,形成托盘的一部分的调平装置,以在烹饪之前使支架平整,以及可旋转的平台组件,用于在支架上旋转荷兰烤箱而不提升荷兰烤箱 从站立。

    ELECTRONIC METHOD AND SYSTEM FOR CONNECTING A BUYER, A SELLER, AND THIRD PARTY COURIER TO FACILITATE THE EXCHANGE OF PHYSICAL GOODS
    8.
    发明申请
    ELECTRONIC METHOD AND SYSTEM FOR CONNECTING A BUYER, A SELLER, AND THIRD PARTY COURIER TO FACILITATE THE EXCHANGE OF PHYSICAL GOODS 审中-公开
    电子方法和系统,用于连接买方,卖方和第三方代理人,以促进物品交换

    公开(公告)号:US20130024232A1

    公开(公告)日:2013-01-24

    申请号:US13551876

    申请日:2012-07-18

    IPC分类号: G06Q30/06 G06Q10/10

    CPC分类号: G06Q30/06

    摘要: Method and system of connecting and facilitating safe and efficient electronic communications between three or more parties for the purpose of an exchange of goods and/or services between the three parties. One embodiment of the present invention uses a software script that connects buyers, sellers, and third party couriers based on how close the parties are physically located to each other. This embodiment is accomplished by having a buyer, a seller, and a courier connect to a remote location-based goods exchange server (remote server) and set up an account.

    摘要翻译: 为了在三方之间交换货物和/或服务的目的,连接和促进三个或更多方之间安全有效的电子通信的方法和系统。 本发明的一个实施例使用一种软件脚本来连接买方,卖方和第三方信使,其方式是基于各方在物理上相互之间的距离。 该实施例通过使买方,卖方和快递连接到远程基于位置的货物交换服务器(远程服务器)并建立帐户来实现。