-
公开(公告)号：US20120009196A1
公开(公告)日：2012-01-12
申请号：US13178810
申请日：2011-07-08
申请人： A Scott Muerhoff , Susan E. Brophy , Bill J. Zeck
发明人： A Scott Muerhoff , Susan E. Brophy , Bill J. Zeck
IPC分类号： A61K39/42 , C12N5/10 , C12N5/22 , C12N1/21 , C12N1/19 , C12Q1/70 , C07K16/10 , C07K16/46 , C12N15/13 , C07K16/00 , A61P31/14 , A61P29/00 , A61P1/00 , A61P11/06 , A61P17/06 , A61P9/10 , A61P37/06 , A61P3/00 , A61P25/14 , A61P31/04 , A61P31/12 , A61P15/08 , A61P37/08 , A61P35/00 , A61P11/00 , A61P9/12 , A61P1/16 , C12N15/63
CPC分类号： C07K16/109 , C07K2317/30 , C07K2317/56 , G01N33/5767 , Y02A50/58
摘要： The present disclosure relates to anti-HCV core protein monoclonal antibodies, methods of making them, and their uses in the prevention, diagnosis, and/or treatment of disease including HCV infections.
摘要翻译： 本公开涉及抗HCV核心蛋白单克隆抗体，其制备方法及其在预防，诊断和/或治疗包括HCV感染的疾病中的用途。
-
公开(公告)号：US08586714B2
公开(公告)日：2013-11-19
申请号：US12873926
申请日：2010-09-01
申请人： Tariq Ghayur , Junjian Liu , Sharmila Manoj , Susan E. Brophy
发明人： Tariq Ghayur , Junjian Liu , Sharmila Manoj , Susan E. Brophy
IPC分类号： C07K16/46 , C07K16/28 , C07K16/44 , C07K16/00 , A61K39/395
CPC分类号： C07K16/468 , A61K45/06 , C07K16/00 , C07K16/2803 , C07K16/2809 , C07K16/2863 , C07K16/2887 , C07K16/30 , C07K16/44 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/515 , C07K2317/64 , C07K2317/732 , C07K2317/92
摘要： The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
-
公开(公告)号：US07998480B2
公开(公告)日：2011-08-16
申请号：US12189232
申请日：2008-08-11
申请人： Susan E. Brophy , Joan D. Tyner , Lowell J. Tyner, legal representative , Bailin X. Tu , Mary S. Pinkus , Jessie W. Shih , Bryan C. Tieman
发明人： Susan E. Brophy , Joan D. Tyner , Bailin X. Tu , Mary S. Pinkus , Jessie W. Shih , Bryan C. Tieman
IPC分类号： A61K39/395 , C12N5/10 , G01N33/53
CPC分类号： C07K16/26 , A61K2039/505 , C07K2317/24 , C07K2317/622 , C07K2317/92 , G01N33/74 , G01N2333/58 , G01N2800/325 , Y10S435/975
摘要： The present invention relates to antibodies that immunospecifically bind to human brain natriuretic peptide or a human brain natriuretic peptide fragment with a high binding affinity, methods for producing and selecting said antibodies, immunoassays for human brain natriuretic peptide or a human brain natriuretic peptide fragment that employ said antibodies and therapeutic compositions containing said antibodies.
摘要翻译： 本发明涉及以高结合亲和力免疫特异性结合人脑利钠肽或人脑利钠肽片段的抗体，用于产生和选择所述抗体的方法，人脑利钠肽的免疫测定或人脑利钠肽片段 所述抗体和含有所述抗体的治疗组合物。
-
公开(公告)号：US20100216720A1
公开(公告)日：2010-08-26
申请号：US12391937
申请日：2009-02-24
申请人： Susan E. Brophy , Bailin Tu , Joan D. Tyner , Dagang Huang , Robert N. Ziemann , Lowell J. Tyner
发明人： Susan E. Brophy , Bailin Tu , Joan D. Tyner , Dagang Huang , Robert N. Ziemann , Lowell J. Tyner
IPC分类号： A61K38/10 , G01N33/53 , C12P21/00 , C12N5/10 , C12N5/06 , C12N1/21 , C12N15/63 , A61K38/08 , C07K16/00 , C07H21/04
CPC分类号： C07K16/18 , C07K14/4716 , C07K2317/24 , C07K2317/565 , C07K2317/622 , C07K2317/92
摘要： The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
摘要翻译： 本发明涉及肌钙蛋白I的抗体及其使用方法。 特别地，这样的抗体可用于检测患者中的肌钙蛋白I，并且也可用于诊断例如心肌梗塞或急性冠状动脉综合征。
-
公开(公告)号：US20120076803A1
公开(公告)日：2012-03-29
申请号：US13319657
申请日：2010-02-23
申请人： Susan E. Brophy , Bailin Tu , Joan D. Tyner , Lowell J. Tyner , Dagang Huang , Robert N. Ziemann
发明人： Susan E. Brophy , Bailin Tu , Joan D. Tyner , Lowell J. Tyner , Dagang Huang , Robert N. Ziemann
IPC分类号： A61K39/395 , C07K16/46 , C07K16/18 , C12N15/13 , C12P21/08 , G01N33/577 , C12N1/21 , C12N1/00 , C12N1/15 , C12N5/10 , C12N1/19 , G01N33/566 , C12N5/071 , G01N33/53
CPC分类号： C07K16/18 , C07K14/4716 , C07K2317/24 , C07K2317/565 , C07K2317/622 , C07K2317/92
摘要： The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
摘要翻译： 本发明涉及肌钙蛋白I的抗体及其使用方法。 特别地，这样的抗体可用于检测患者中的肌钙蛋白I，并且也可用于诊断例如心肌梗塞或急性冠状动脉综合征。
-
公开(公告)号：US20110091372A1
公开(公告)日：2011-04-21
申请号：US12873926
申请日：2010-09-01
申请人： Tariq Ghayur , Junjian Liu , Sharmila Manoj , Susan E. Brophy
发明人： Tariq Ghayur , Junjian Liu , Sharmila Manoj , Susan E. Brophy
IPC分类号： A61K51/00 , C07K16/00 , C12N9/96 , C07H21/04 , C12N15/63 , C12N1/21 , C12N5/10 , C12N1/11 , C12N1/15 , C12N1/19 , C12P21/00 , A61K39/395 , A61P19/02 , A61P35/00 , A61P25/28 , A61P9/10 , A61P31/12 , A61P5/50 , A61P37/06 , A61P17/06
CPC分类号： C07K16/468 , A61K45/06 , C07K16/00 , C07K16/2803 , C07K16/2809 , C07K16/2863 , C07K16/2887 , C07K16/30 , C07K16/44 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/515 , C07K2317/64 , C07K2317/732 , C07K2317/92
摘要： The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
-
公开(公告)号：US20100015637A1
公开(公告)日：2010-01-21
申请号：US12485114
申请日：2009-06-16
申请人： Susan E. Brophy , Lianli Chi , Saul A. Datwyler , David J. Hawksworth , Don M. Laird , Sharmila Manoj , Mary S. Pinkus , Dominick L. Pucci , Carol S. Ramsay , David C. Sogin , Bailin Tu , Joan D. Tyner , Lowell J Tyner , Zhiguang Yu , Robert N. Ziemann
发明人： Susan E. Brophy , Lianli Chi , Saul A. Datwyler , David J. Hawksworth , Don M. Laird , Sharmila Manoj , Mary S. Pinkus , Dominick L. Pucci , Carol S. Ramsay , David C. Sogin , Bailin Tu , Joan D. Tyner , Lowell J Tyner , Zhiguang Yu , Robert N. Ziemann
CPC分类号： C07K16/22 , C07K14/475 , C07K2317/92 , G01N33/74 , G01N2333/475
摘要： The present disclosure relates to glycosylated and deglycosylated human PlGF-1, methods of using the glycosylated and deglycosylated human PlGF-1, antibodies that bind to human PlGF-1, methods of using the antibodies and human PlGF-1 immunoassays and kits.
摘要翻译： 本公开涉及糖基化和去糖基化的人PlGF-1，使用糖基化和去糖基化的人PlGF-1的方法，与人PlGF-1结合的抗体，使用抗体和人PlGF-1免疫测定和试剂盒的方法。
-
公开(公告)号：US20090123473A1
公开(公告)日：2009-05-14
申请号：US12189232
申请日：2008-08-11
申请人： Susan E. Brophy , Joan D. Tyner , Bailin X. Tu , Mary S. Pinkus , Jessie W. Shih , Bryan C. Tieman , Lowell J. Tyner
发明人： Susan E. Brophy , Joan D. Tyner , Bailin X. Tu , Mary S. Pinkus , Jessie W. Shih , Bryan C. Tieman , Lowell J. Tyner
IPC分类号： A61K31/395 , C07K16/00 , C12N5/06 , G01N33/53
CPC分类号： C07K16/26 , A61K2039/505 , C07K2317/24 , C07K2317/622 , C07K2317/92 , G01N33/74 , G01N2333/58 , G01N2800/325 , Y10S435/975
摘要： The present invention relates to antibodies that immunospecifically bind to human brain natriuretic peptide or a human brain natriuretic peptide fragment with a high binding affinity, methods for producing and selecting said antibodies, immunoassays for human brain natriuretic peptide or a human brain natriuretic peptide fragment that employ said antibodies and therapeutic compositions containing said antibodies.
摘要翻译： 本发明涉及以高结合亲和力免疫特异性结合人脑利钠肽或人脑利钠肽片段的抗体，用于产生和选择所述抗体的方法，人脑利钠肽的免疫测定或人脑利钠肽片段 所述抗体和含有所述抗体的治疗组合物。
-
公开(公告)号：US08741287B2
公开(公告)日：2014-06-03
申请号：US12485114
申请日：2009-06-16
申请人： Susan E. Brophy , Lianli Chi , Saul A Datwyler , David J. Hawksworth , Don M. Laird , Sharmila Manoj , Mary S. Pinkus , Dominick L. Pucci , Carol S. Ramsay , David C. Sogin , Bailin Tu , Zhiguang Yu , Robert N. Ziemann , Lowell J. Tyner
发明人： Susan E. Brophy , Lianli Chi , Saul A Datwyler , David J. Hawksworth , Don M. Laird , Sharmila Manoj , Mary S. Pinkus , Dominick L. Pucci , Carol S. Ramsay , David C. Sogin , Bailin Tu , Joan D. Tyner , Zhiguang Yu , Robert N. Ziemann
IPC分类号： A61K39/395 , C12Q3/00 , G01N33/53
CPC分类号： C07K16/22 , C07K14/475 , C07K2317/92 , G01N33/74 , G01N2333/475
摘要： The present disclosure relates to glycosylated and deglycosylated human PlGF-1, methods of using the glycosylated and deglycosylated human PlGF-1, antibodies that bind to human PlGF-1, methods of using the antibodies and human PlGF-1 immunoassays and kits.
摘要翻译： 本公开涉及糖基化和去糖基化的人PlGF-1，使用糖基化和去糖基化的人PlGF-1的方法，与人PlGF-1结合的抗体，使用抗体和人PlGF-1免疫测定和试剂盒的方法。
-
公开(公告)号：US20120122125A1
公开(公告)日：2012-05-17
申请号：US13353678
申请日：2012-01-19
申请人： Susan E. Brophy , David J. Hawksworth , Dinesh O. Shah , Robert W. Siegel , Bryan C. Tieman , Bailin Tu , Joan D. Tyner , Robert N. Ziemann
发明人： Susan E. Brophy , David J. Hawksworth , Dinesh O. Shah , Robert W. Siegel , Bryan C. Tieman , Bailin Tu , Joan D. Tyner , Robert N. Ziemann
CPC分类号： G01N33/56905 , C07K16/20 , C07K2317/24 , C07K2317/56 , C07K2317/92 , G01N2333/44 , G01N2469/10 , G01N2469/20 , G01N2496/00
摘要： The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
摘要翻译： 本公开涉及使用试剂检测克氏锥虫的表位的试剂和方法。
-
-
-
-
-
-
-
-
-
搜索结果
22 条记录 (耗时 0.041 秒)
