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公开(公告)号：US20150266332A1
公开(公告)日：2015-09-24
申请号：US14661489
申请日：2015-03-18
申请人： APDN (B.V.I.) INC.
IPC分类号： B42D25/415 , B42D25/36
CPC分类号： C09K11/06 , B29C65/4825 , B29C66/733 , B41M3/142 , B41M3/144 , B42D2035/34 , G07D7/14
摘要： Encrypted markers that are not readily detectable can be revealed by treatment with a specific reagent used as a developer to reveal a readily detectable physical property of the marker, such as a characteristic fluorescence emission after excitation with a particular excitation wavelength, or to reveal a visible color. The encrypted marker can be developed in situ, or a sample can be removed by brushing, scraping, swabbing or scratching the marked object or item and developing the encrypted marker or a sample thereof with the appropriate developer to reveal an overt marker or optical signal. The marker can be revealed by exposure of the encrypted marker or a sample thereof to the developer in any suitable form, such as a solution, a slurry, a swab, a solid (such as in granular form), or a gas or a vapor that includes a developer.
摘要翻译： 通过用用作显色剂的特定试剂进行处理，可以显示不容易检测到的加密标记物，以显示标记的易于检测的物理性质，例如用特定激发波长激发后的特征性荧光发射，或显示可见光 颜色。 可以原位开发加密的标记，或者可以通过刷涂，刮擦，擦拭或刮擦标记的物体或物品并用合适的显影剂开发加密标记或样品，以揭示公开标记或光信号来移除样品。 可以通过将加密的标记物或其样品以任何合适的形式（例如溶液，浆液，拭子，固体（例如颗粒形式））或气体或蒸汽暴露于显影剂来显示标记 包括开发人员。
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公开(公告)号：US20160102215A1
公开(公告)日：2016-04-14
申请号：US14969582
申请日：2015-12-15
申请人： APDN (B.V.I.) INC.
CPC分类号： C09D7/80 , B41M3/14 , B41M5/0023 , C08K5/09 , C09D5/22 , C09D7/20 , C09D7/63 , C09D11/03 , C09D135/04 , C12Q1/6816 , C12Q1/686 , G01N21/6428 , G01N2021/6439 , G07D7/14 , C12Q2563/185
摘要： Methods for authenticating an article with a cyanoacrylate solution comprising a water soluble security marker compound are described. The methods for producing a nucleophilic security marker/cyanoacrylate solution as well as methods for labeling an item and detecting the nucleophilic security marker/cyanoacrylate from an item being authenticated are also described. A method for using a nucleophilic cyanoacrylate security marker for antitheft purposes is also described.
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3.发明申请SECURITY SYSTEM AND METHOD OF MARKING AN INVENTORY ITEM AND/OR PERSON IN THE VICINITY 审中-公开保护系统和标记物品和/或人员的方法公开(公告)号：US20150302713A1
公开(公告)日：2015-10-22
申请号：US14570242
申请日：2014-12-15
申请人： APDN (B.V.I.) Inc.
摘要： A method of marking an inventory item includes providing an activatable smoke generator and a reservoir for holding a smoke fluid and adapted to provide a flow of smoke fluid to the generator. The reservoir contains a smoke fluid including a carrier nucleic acid having a uniquely identifiable sequence, and upon activation of the smoke generator, marker smoke is generated and targeted to flow over the inventory item. The method further includes activating the smoke generator to produce the marker smoke including the carrier nucleic acid so as to cause the marker smoke to flow over the inventory item and thereby to detectably mark the inventory item with carrier nucleic acid.
摘要翻译： 标记库存物品的方法包括提供可激活的烟雾发生器和用于保持烟雾流体并适合于向发生器提供烟雾流体的贮存器。 储存器包含烟液，其包括具有唯一可识别顺序的载体核酸，并且在激活烟雾发生器时，产生标记烟雾并将其靶向流过库存物品。 该方法还包括激活烟雾发生器以产生包括载体核酸的标记烟，以使标记物烟雾流过库存物品，从而用载体核酸可检测地标记库存物品。
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公开(公告)号：US20150107475A1
公开(公告)日：2015-04-23
申请号：US14584100
申请日：2014-12-29
申请人： APDN (B.V.I.) Inc.
IPC分类号： B41M3/14
CPC分类号： B41F17/00 , B41M3/14 , B42D25/378 , B42D25/405 , C12Q1/68 , G07D7/14 , Y10T29/49826 , Y10T29/49885
摘要： The invention provides a method of marking an item with naturally-derived or synthetic non-natural polymeric marker molecules, such as a DNA or Peptide marker in conjunction with optional visible or rapid scan reporters for authenticating or tracking, in which the method includes providing an item for marking, and applying a medium including a DNA marker to the item. The invention further provides methods for stably binding and immobilizing activated deoxyribonucleic acid onto objects and substrates. The method includes exposing the deoxyribonucleic acid to alkaline conditions, and contacting the deoxyribonucleic acid to the object or substrate. Also provided are methods for increasing the recoverability of taggants from an object. The methods include the steps of incorporating a taggant into a solution; mixing the solution including the taggant with a perturbant to form a first perturbant taggant solution; mixing the first perturbant taggant solution with a polymer to form a second perturbant taggant polymer solution; and applying the second perturbant taggant polymer solution to at least a portion of the object to form a taggant-coated object. The invention also provides a method of marking an item with a DNA marker for authenticating or tracking, in which the method includes providing a medium including a DNA marker, and molding the medium including the DNA marker to provide all or part of the item. The DNA marker encodes information unique to the item and/or the model of the item as desired.
摘要翻译： 本发明提供了一种使用天然衍生或合成的非天然聚合物标记分子（例如DNA或肽标记）与用于鉴定或跟踪的可选的可见或快速扫描记录器一起标记物品的方法，其中所述方法包括提供 用于标记的项目，以及将包括DNA标记的培养基应用于该物品。 本发明还提供了将活化的脱氧核糖核酸稳定结合并固定在物体和底物上的方法。 该方法包括将脱氧核糖核酸暴露于碱性条件下，并使脱氧核糖核酸与对象或底物接触。 还提供了用于增加标签从对象的可恢复性的方法。 所述方法包括将标签剂掺入溶液中的步骤; 将包含标签剂的溶液与扰动剂混合以形成第一扰动标记剂溶液; 将第一扰动标记剂溶液与聚合物混合以形成第二扰动标记聚合物溶液; 以及将所述第二扰动标记聚合物溶液施加到所述物体的至少一部分以形成标记剂涂覆物体。 本发明还提供了用用于鉴定或追踪的DNA标记物标记物品的方法，其中所述方法包括提供包含DNA标记物的培养基，并且模制包含DNA标记的培养基以提供该物品的全部或部分。 DNA标记根据需要编码项目和/或项目模型唯一的信息。
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公开(公告)号：US20160326511A1
公开(公告)日：2016-11-10
申请号：US15212429
申请日：2016-07-18
申请人： APDN (B.V.I.) INC.
IPC分类号： C12N15/10 , B01J19/08 , G01N27/447 , C12Q1/68
CPC分类号： C12N15/101 , B01J19/08 , B01J19/088 , B01J2219/0879 , B01J2219/0894 , B01J2219/24 , C12N15/1006 , C12Q1/6806 , G01N27/447 , G01N27/44791
摘要： The invention provides a composition including DNA bonded to a plasma-treated surface, the plasma can be any suitable plasma, such as an argon plasma, a compressed air plasma, a flame-based plasma or a vacuum plasma. Surfaces treatable by the methods of the invention include ceramic, metal, fabric and organic polymer surfaces. The DNA can be any DNA, such as a marker DNA, which can be linear or circular, single-stranded or double stranded and from about 25 bases to about 10,000 bases in length. Also provided is a method of binding DNA to a surface, including the steps of exposing the surface to a plasma to produce a plasma-treated surface; and applying DNA to the plasma-treated surface to produce surface bound DNA on the treated surface. A system for binding DNA to a surface is also disclosed, the system includes a plasma generator adapted to treating a surface with a plasma to produce a plasma-treated surface; and an applicator containing DNA adapted to applying DNA to the plasma-treated surface to produce surface bound DNA on the plasma-treated surface.
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公开(公告)号：US20160168781A1
公开(公告)日：2016-06-16
申请号：US14572552
申请日：2014-12-16
申请人： APDN (B.V.I.) Inc.
IPC分类号： D06M13/453 , D06B1/02 , D01B1/04 , C12Q1/68
摘要： A method of marking fibers, wherein the method includes providing a plurality of fibers; depositing a marker onto at least a portion of the fibers, the depositing being performed with a delivery mechanism comprising one or more outlets; and thereby marking the fibers. Also provided is a device for marking fibers, including a transport system adapted to transport fibers in a direction of a marker delivery apparatus positioned along the transport system; the delivery apparatus includes one or more outlets, adapted to deposit a solution of the marker through the outlets onto at least a portion of the fibers; and thereby marking the fibers. Authentication of a fibrous material using the marking method of the invention followed obtaining a sample of the marked fibers and assaying the sample for the presence of the nucleic acid marker; and thereby determining whether the fibrous material is authentic or counterfeit.
摘要翻译： 一种标记纤维的方法，其中该方法包括提供多根纤维; 将标记沉积在纤维的至少一部分上，用包括一个或多个出口的递送机构进行沉积; 从而标记纤维。 还提供了一种用于标记纤维的装置，包括适于沿沿输送系统定位的标记输送装置的方向输送纤维的输送系统; 输送装置包括一个或多个出口，适于将标记物的溶液通过出口沉积到纤维的至少一部分上; 从而标记纤维。 然后使用本发明的标记方法鉴定纤维材料，然后获得标记的纤维样品并测定样品中核酸标记物的存在; 从而确定纤维材料是真实的还是假的。
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公开(公告)号：US20180312998A1
公开(公告)日：2018-11-01
申请号：US16028176
申请日：2018-07-05
申请人： APDN (B.V.I.) INC.
IPC分类号： C40B20/04 , B41M3/14 , G07D7/14 , G07D7/1205
CPC分类号： C40B20/04 , B41M3/142 , B41M3/144 , B42D25/00 , C09B11/08 , C09B11/22 , C09B11/24 , C09B23/164 , C09B57/10 , C09B69/103 , C12Q1/68 , C12Q1/6876 , G07D7/1205 , G07D7/14 , G07D7/205 , C12Q2563/185
摘要： Encrypted markers that are not readily detectable can be revealed by treatment with a specific reagent used as a developer to reveal a readily detectable physical property of the marker, such as a characteristic fluorescence emission after excitation with a particular excitation wavelength, or to reveal a visible color. The encrypted marker can be developed in situ, or a sample can be removed by brushing, scraping, swabbing or scratching the marked object or item and developing the encrypted marker or a sample thereof with the appropriate developer to reveal an overt marker or optical signal. The encrypted marker may include a DNA taggant.
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公开(公告)号：US20160246892A1
公开(公告)日：2016-08-25
申请号：US15027454
申请日：2014-10-07
申请人： APDN (B.V.I.), INC.
发明人： Judith MURRAH , Phidung H. TRAN , Maciej B. SZCZEPANIK , MingHwa Benjamin LIANG , James A. HAYWARD
CPC分类号： G06F17/30876 , G06K7/0004 , G06K19/06037 , G06K19/0723
摘要： A multi-mode reader instrument capable of detecting and determining digital data from a signal from one or more markers, indicia or taggants on an object, the markers, indicia or taggants such as a bar code, a QR code, an RFID, an optical compound, a fluorescent compound, a phosphorescent compound, a DNA taggant, an upconverting phosphor (UCP), a chemical dye, a digitized image, a radioactive compound, an olfactory compound or a thermal attribute of the object is provided. Also, provided is a method and a system for identifying an object, the system includes: a multi-mode reader instrument for detecting data from a signal from one or more markers, indicia or taggants on an object and assignment of digital code for the marker and a database for securing and retrieving information relevant to the item.
摘要翻译： 能够从物体上的一个或多个标记，标记或标记的信号检测和确定数字数据的多模式读取器仪器，标记，标记或标签，例如条形码，QR码，RFID，光学 化合物，荧光化合物，磷光化合物，DNA标记物，上转换荧光体（UCP），化学染料，数字化图像，放射性化合物，嗅觉化合物或热物性。 此外，提供了一种用于识别对象的方法和系统，该系统包括：多模式读取器工具，用于从来自一个或多个标记，对象上的标记或标记的信号和用于标记的数字代码的分配来检测数据 以及用于保护和检索与该项目相关的信息的数据库。
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公开(公告)号：US20150275271A1
公开(公告)日：2015-10-01
申请号：US14666578
申请日：2015-03-24
申请人： APDN (B.V.I.) INC.
IPC分类号： C12Q1/68 , G01N27/447 , B01J19/08
CPC分类号： C12N15/101 , B01J19/08 , B01J19/088 , B01J2219/0879 , B01J2219/0894 , B01J2219/24 , C12N15/1006 , C12Q1/6806 , G01N27/447 , G01N27/44791
摘要： The invention provides a composition including DNA bonded to a plasma-treated surface, the plasma can be any suitable plasma, such as an argon plasma, a compressed air plasma, a flame-based plasma or a vacuum plasma. Surfaces treatable by the methods of the invention include ceramic, metal, fabric and organic polymer surfaces. The DNA can be any DNA, such as a marker DNA, which can be linear or circular, single-stranded or double stranded and from about 25 bases to about 10,000 bases in length. Also provided is a method of binding DNA to a surface, including the steps of exposing the surface to a plasma to produce a plasma-treated surface; and applying DNA to the plasma-treated surface to produce surface bound DNA on the treated surface. A system for binding DNA to a surface is also disclosed, the system includes a plasma generator adapted to treating a surface with a plasma to produce a plasma-treated surface; and an applicator containing DNA adapted to applying DNA to the plasma-treated surface to produce surface bound DNA on the plasma-treated surface.
摘要翻译： 本发明提供了包含结合到等离子体处理表面的DNA的组合物，等离子体可以是任何合适的等离子体，例如氩等离子体，压缩空气等离子体，基于火焰的等离子体或真空等离子体。 可通过本发明的方法处理的表面包括陶瓷，金属，织物和有机聚合物表面。 DNA可以是任何DNA，例如标记DNA，其可以是线性或环状，单链或双链，并且长度为约25碱基至约10,000碱基。 还提供了将DNA结合到表面的方法，包括将表面暴露于等离子体以产生等离子体处理的表面的步骤; 并将DNA施加到等离子体处理的表面上以在被处理的表面上产生表面结合的DNA。 还公开了将DNA结合到表面的系统，该系统包括适于用等离子体处理表面以产生等离子体处理的表面的等离子体发生器; 以及包含适于将DNA施加到等离子体处理的表面以在等离子体处理的表面上产生表面结合的DNA的DNA的施加器。
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公开(公告)号：US20150191799A1
公开(公告)日：2015-07-09
申请号：US14584309
申请日：2014-12-29
申请人： APDN (B.V.I.) Inc.
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6895 , C12Q2600/13 , C12Q2600/156
摘要： Methods for distinguishing between cotton cultivars of a specific species by analyzing a sample of mature cotton fibers from raw cotton materials or from textile goods are disclosed. DNA is extracted from the mature cotton fiber sample and subjected to PCR techniques which enable the identification of the cultivar of a particular cotton species utilized in the textile or cotton material of interest.
摘要翻译： 公开了通过从原棉材料或纺织品分析成熟棉纤维样品来区分特定物种的棉花品种的方法。 从成熟棉花纤维样品中提取DNA，并进行PCR技术，其能够鉴定在感兴趣的纺织品或棉花材料中使用的特定棉花品种的品种。
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