公开(公告)号：US20180371158A1

公开(公告)日：2018-12-27

申请号：US16063470

申请日：2016-12-19

申请人： Abraham Joy ,  Tanmay Jain

发明人： Abraham Joy ,  Tanmay Jain

IPC分类号： C08G63/685 ,  A61L27/18 ,  A61L27/54 ,  C08G18/60

摘要： A controlled release polymer is provided which includes a polymer that has backbone selected from polyesters and polyurethanes, and an amide group with a pendant functional group, where the nitrogen atom of the amide group is part of the polymer backbone, and an active compound dispersed in the polymer. The active compound may be released over time from the controlled release polymer

公开(公告)号：US11542359B2

公开(公告)日：2023-01-03

申请号：US16325761

申请日：2017-08-24

申请人： Abraham Joy ,  Kaushik Mishra ,  Yen-Ming Tseng

发明人： Abraham Joy ,  Kaushik Mishra ,  Yen-Ming Tseng

IPC分类号： C08G18/66 ,  C08G18/48 ,  C08G18/75 ,  C09J175/08 ,  C08L33/14 ,  C08G18/28 ,  C08G18/10 ,  C08G18/32 ,  C09D175/08

摘要： A photoresponsive polyurethane including a hard segment, a soft segment, and a photoresponsive group that is selected from a coumarin group or a coumarin derivative and an alkoxyphencyl group or an alkoxyphencyl.

公开(公告)号：US20190211135A1

公开(公告)日：2019-07-11

申请号：US16325761

申请日：2017-08-24

申请人： Abraham Joy ,  Kaushik Mishra ,  Yen-Ming Tseng

发明人： Abraham Joy ,  Kaushik Mishra ,  Yen-Ming Tseng

IPC分类号： C08G18/66 ,  C08G18/48 ,  C08G18/32 ,  C08G18/75 ,  C09D175/08 ,  C09J175/08

CPC分类号： C08G18/6677 ,  C08G18/10 ,  C08G18/283 ,  C08G18/3206 ,  C08G18/3218 ,  C08G18/4825 ,  C08G18/755 ,  C08L33/14 ,  C09D175/08 ,  C09J175/08 ,  C09J2205/31 ,  C08G18/3215

摘要： A photoresponsive polyurethane including a hard segment, a soft segment, and a photoresponsive group that is selected from a coumarin group or a coumarin derivative and an alkoxyphencyl group or an alkoxyphencyl.

公开(公告)号：US20170081568A1

公开(公告)日：2017-03-23

申请号：US15311319

申请日：2015-05-15

申请人： Abraham Joy ,  Ali Dhinojwala ,  Kaushik Mishra

发明人： Abraham Joy ,  Ali Dhinojwala ,  Kaushik Mishra

IPC分类号： C09J133/08 ,  A61L15/58 ,  A61F13/02 ,  C09B57/02 ,  B32B27/06 ,  C09J7/02 ,  A61L15/24

CPC分类号： C09J133/08 ,  A61F13/0253 ,  A61L15/24 ,  A61L15/58 ,  B32B27/06 ,  B32B2307/41 ,  B32B2307/412 ,  B32B2535/00 ,  C09B57/02 ,  C09B69/109 ,  C09J7/385 ,  G03F7/039

摘要： Provided is a pressure sensitive adhesive polymer comprising adhesive polymerscrosslinked with a crosslinker that includes a photoresponsive group. Also provided is a method for preparing a pressure sensitive adhesive polymer comprising: polymerizing an vinyl monomer and photoresponsive crosslinker with two acryl end groups.

公开(公告)号：US10336923B2

公开(公告)日：2019-07-02

申请号：US15311319

申请日：2015-05-15

申请人： Abraham Joy ,  Ali Dhinojwala ,  Kaushik Mishra

发明人： Abraham Joy ,  Ali Dhinojwala ,  Kaushik Mishra

IPC分类号： C08F2/46 ,  C08F2/50 ,  C08G61/04 ,  C09J133/08 ,  C09B57/02 ,  G03F7/039 ,  C09B69/10 ,  A61F13/02 ,  A61L15/24 ,  A61L15/58 ,  B32B27/06 ,  C09J7/02

摘要： Provided is a pressure sensitive adhesive polymer comprising adhesive polymerscrosslinked with a crosslinker that includes a photoresponsive group. Also provided is a method for preparing a pressure sensitive adhesive polymer comprising: polymerizing an vinyl monomer and photoresponsive crosslinker with two acryl end groups.

公开(公告)号：US20160002389A1

公开(公告)日：2016-01-07

申请号：US14776006

申请日：2014-03-14

申请人： Abraham JOY ,  Chao PENG

发明人： Abraham Joy ,  Chao Peng

IPC分类号： C08G18/83 ,  C08G63/688 ,  C08G18/38

CPC分类号： C08G18/835 ,  C08G18/244 ,  C08G18/34 ,  C08G18/3868 ,  C08G18/67 ,  C08G18/73 ,  C08G63/6886 ,  C08K2201/011

摘要： A method of preparing a polymer is provided comprising preparing a Baylis-Hillman adduct by reacting an activated alkene with a carbon electrophile; and polymerizing the Baylis-Hillman adduct. The Baylis-Hillman reaction provides an efficient platform for the synthesis of densely functionalized monomers, from which polymers with multiple functional groups can be readily synthesized. It has been discovered that that Baylis-Hillman adducts are versatile monomers for both controlled radical and step-growth polymerizations.

摘要翻译： 提供一种制备聚合物的方法，包括通过使活化烯与碳亲电子试剂反应制备Baylis-Hillman加合物; 并使Baylis-Hillman加合物聚合。 Baylis-Hillman反应为致密官能化单体的合成提供了有效的平台，可以容易地合成具有多个官能团的聚合物。 已经发现，Baylis-Hillman加合物是用于受控自由基和逐步增长聚合的通用单体。

公开(公告)号：US20150274885A1

公开(公告)日：2015-10-01

申请号：US14440645

申请日：2013-11-08

申请人： Abraham Joy ,  Murthy V.S.N. Maddipatla

发明人： Abraham Joy ,  Murthy V.S.N. Maddipatla

IPC分类号： C08G63/60 ,  G03F7/038 ,  A61K9/48 ,  C05G3/00 ,  A61K8/11 ,  A61Q19/00 ,  A01N25/34 ,  A61L27/18 ,  C07D311/18

CPC分类号： C08G63/60 ,  A01N25/10 ,  A01N25/34 ,  A61K8/0216 ,  A61K8/11 ,  A61K8/85 ,  A61K8/87 ,  A61K9/4816 ,  A61K2800/10 ,  A61K2800/54 ,  A61K2800/56 ,  A61K2800/81 ,  A61L27/18 ,  A61L2430/02 ,  A61Q19/00 ,  C05G3/0017 ,  C05G3/0029 ,  C07D311/18 ,  C08G18/3206 ,  C08G18/4854 ,  C08G18/6511 ,  C08G18/6705 ,  C09B57/02 ,  C09B69/109 ,  G03F7/038

摘要： A photoactive coumarin monomer includes a substituted coumarin molecule that has at least two functional groups may be used to produce a polymer with a coumarin unit or a coumarin derivative unit as part of the polymer backbone. The polymer with a coumarin unit or a coumarin derivative unit as part of the polymer backbone may be photoresponsive and/or bioabsorbable. Photoresponsive polymers with a coumarin unit or a coumarin derivative unit as part of the polymer backbone may crosslink when irradiated at a wavelength of about 320 nm to about 420 nm. The crosslink may be separated when the polymers are irradiated at a wavelength of about 230 nm to about 300. The polymers may also photocleave when irradiated with light at a wavelength of about 230 nm to about 300.

摘要翻译： 光活性香豆素单体包括具有至少两个官能团的取代香豆素分子，其可用于制备具有香豆素单元或香豆素衍生物单元的聚合物作为聚合物主链的一部分。 具有香豆素单元或香豆素衍生物单元作为聚合物主链的一部分的聚合物可以是光响应和/或生物可吸收的。 具有香豆素单元或作为聚合物主链的一部分的香豆素衍生物单元的光响应聚合物可在约320nm至约420nm的波长照射时交联。 当聚合物在约230nm至约300的波长下照射时，可以分离交联。当用约230nm至约300的波长的光照射时，聚合物也可以光洗。

公开(公告)号：US20190297883A1

公开(公告)日：2019-10-03

申请号：US16438559

申请日：2019-06-12

申请人： Abraham Joy ,  Chao Peng ,  Zhuoran Li ,  Nicholas Nun ,  Apoorva Vishwakarma

发明人： Abraham Joy ,  Chao Peng ,  Zhuoran Li ,  Nicholas Nun ,  Apoorva Vishwakarma

IPC分类号： A01N33/08 ,  C08G18/73 ,  C08G18/75 ,  C08G18/48 ,  C08G18/38 ,  C08G18/32 ,  C08G18/10 ,  C08G18/24 ,  C08J5/18 ,  A61L2/23

摘要： A functionalized polyurethane polymer is provided, the polymer defined by the formula where each R′ is independently derived from a diisocyanate, where each R″ represents the soft segment of the polymer, where n is the number of repeat units within the soft segment of the polymer, where m is the number of repeating mer units in the polymer, where each E is a pendant-functionalized amide unit chain extender, wherein the nitrogen atom of the amide group is part of the polymer backbone. A method for preparing the polymer is also provided.

公开(公告)号：US20170247506A1

公开(公告)日：2017-08-31

申请号：US15432160

申请日：2017-02-14

申请人： Abraham Joy ,  Sachin Gokhale ,  Ying Xu

发明人： Abraham Joy ,  Sachin Gokhale ,  Ying Xu

IPC分类号： C08G63/91 ,  C08G18/38 ,  C08G18/73 ,  C08G63/685 ,  C09B69/10

CPC分类号： C08G63/91 ,  C08G18/3275 ,  C08G18/3825 ,  C08G18/73 ,  C08G63/685 ,  C08G63/6856 ,  C08G63/916 ,  C08G73/0233 ,  C09B69/109

摘要： Amide compounds are defined and are polymerized to create polyesters and polyurethanes having amide units bearing a pendant functional group, where the nitrogen atom of the amide group is part of the polymer backbone. The pendant functional group of the functionalized amide polymer may be modified or added by post polymerization functionalization of the functionalized amide polymer. The pendant functional group of the functionalized amide polymer may include a protecting group that may be removed after polymerization. The pendant functional groups of the functionalized amide polymers may be used to modulate the physical, chemical and biological properties of the polymers.

公开(公告)号：US09663614B2

公开(公告)日：2017-05-30

申请号：US14440645

申请日：2013-11-08

申请人： Abraham Joy ,  Murthy V. S. N. Maddipatla

发明人： Abraham Joy ,  Murthy V. S. N. Maddipatla

IPC分类号： C07D311/08 ,  C08F24/00 ,  C08G63/60 ,  C07D311/18 ,  C08G18/48 ,  C08G18/65 ,  C08G18/67 ,  C08G18/32 ,  A01N25/34 ,  A61K8/11 ,  A61K9/48 ,  A61L27/18 ,  A61Q19/00 ,  C05G3/00 ,  G03F7/038

CPC分类号： C08G63/60 ,  A01N25/10 ,  A01N25/34 ,  A61K8/0216 ,  A61K8/11 ,  A61K8/85 ,  A61K8/87 ,  A61K9/4816 ,  A61K2800/10 ,  A61K2800/54 ,  A61K2800/56 ,  A61K2800/81 ,  A61L27/18 ,  A61L2430/02 ,  A61Q19/00 ,  C05G3/0017 ,  C05G3/0029 ,  C07D311/18 ,  C08G18/3206 ,  C08G18/4854 ,  C08G18/6511 ,  C08G18/6705 ,  C09B57/02 ,  C09B69/109 ,  G03F7/038

摘要： A photoactive coumarin monomer includes a substituted coumarin molecule that has at least two functional groups may be used to produce a polymer with a coumarin unit or a coumarin derivative unit as part of the polymer backbone. The polymer with a coumarin unit or a coumarin derivative unit as part of the polymer backbone may be photoresponsive and/or bioabsorbable. Photoresponsive polymers with a coumarin unit or a coumarin derivative unit as part of the polymer backbone may crosslink when irradiated at a wavelength of about 320 nm to about 420 nm. The crosslink may be separated when the polymers are irradiated at a wavelength of about 230 nm to about 300. The polymers may also photocleave when irradiated with light at a wavelength of about 230 nm to about 300.