摘要:
The present invention relates to a cartridge for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample comprising one or more nucleic acid sequences. The cartridge comprises a first component and a second component being connectable to each other, the first component comprising at least a first fluid opening and a first sealing surface and the second component comprising at least a second fluid opening and a second sealing surface. Upon connection of the first and second component the first and second fluid opening are placeable in fluid communication and the first and second sealing surfaces are placeable against each other to seal the fluid communication between the first and second fluid opening. The invention is characterized in that the cartridge comprises biasing means for biasing the second sealing surface in the direction of the first sealing surface.
摘要:
The invention provides an apparatus for moving magnetic particles in a liquid medium, a system comprising an apparatus, a method for moving magnetic particles and a method for moving and for fixing the magnetic particles. The apparatus comprises a first magnetic means generating a first magnetic field, the apparatus further comprising a second magnetic means generating a second magnetic field, the first magnetic field having a first main axis, the second magnetic field having a second main axis, wherein the first and second main axes are inclined relative to each other by an acute angle of inclination.
摘要:
The invention provides a device for mixing a liquid medium, an apparatus for mixing a liquid medium, a system comprising a device and an apparatus and a method for mixing a liquid medium. The device comprises a flexible membrane (12) and a structural part (16), which device further comprises an actuation part (14) located on a first side of the membrane, which device further comprises a mixing chamber (20) located on a second side of the membrane, wherein at least a partial inclination of the membrane results from an inclination of the actuation part relative to the structural part.
摘要:
The present invention relates to a valve device (10) comprising a substrate (12) and an elastic membrane (13), the membrane being joined at least around a valve area to the substrate. The substrate comprises a first channel (16) and a second channel (17), both ending in the valve area, the first channel having in the valve area a first channel end surface (19) and the second channel having in the valve area a second channel end surface (21), wherein the area of the first channel end surface is substantially larger than the area of the second channel end surface.
摘要:
The present invention relates to a valve device (10) comprising a substrate (12) and an elastic membrane (13), the membrane being joined at least around a valve area to the substrate. The substrate comprises a first channel (16) and a second channel (17), both ending in the valve area, the first channel having in the valve area a first channel end surface (19) and the second channel having in the valve area a second channel end surface (21), wherein the area of the first channel end surface is substantially larger than the area of the second channel end surface.
摘要:
The invention relates to a coupling system that can particularly be applied for interfacing a consumable component with a sample chamber to a laboratory instrument for processing a sample fluid. The coupling system comprises a female interface module (10) integrated into the consumable component that has an elastic sealing component (12) with a preformed channel (12a). Moreover, it comprises a male interface module (20) integrated into the instrument and comprising a hollow needle (23) fixed in a first section (22a) of a bush (22), wherein the flexible free end of said needle (23) is partially surrounded by a second section (22b) of the bush that limits the lateral movement of the needle. The diameter of the channel in the sealing component (12) is preferably smaller than the diameter (d) of the needle (23), thus providing an airtight connection and a self-cleaning effect.
摘要:
The invention provides a device for mixing a liquid medium, an apparatus for mixing a liquid medium, a system comprising a device and an apparatus and a method for mixing a liquid medium. The device comprises a flexible membrane (12) and a structural part (16), which device further comprises an actuation part (14) located on a first side of the membrane, which device further comprises a mixing chamber (20) located on a second side of the membrane, wherein at least a partial inclination of the membrane results from an inclination of the actuation part relative to the structural part.
摘要:
The present invention relates to a cartridge for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample comprising one or more nucleic acid sequences. The cartridge comprises a first component and a second component being connectable to each other, the first component comprising at least a first fluid opening and a first sealing surface and the second component comprising at least a second fluid opening and a second sealing surface. Upon connection of the first and second component the first and second fluid opening are placeable in fluid communication and the first and second sealing surfaces are placeable against each other to seal the fluid communication between the first and second fluid opening. The invention is characterized in that the cartridge comprises biasing means for biasing the second sealing surface in the direction of the first sealing surface.
摘要:
Disclosed is a cartridge for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample comprising one or more nucleic acid sequences. The cartridge comprises a generic part and one or more separate application-specific parts, which are connectable to the generic part. Also disclosed is a system for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample comprising one or more nucleic acid sequences. This system comprising a reusable apparatus, wherein said apparatus is configured to receive a cartridge and to control a process for the detection of the presence, absence and/or amount of a target nucleotide sequence in the sample, being present in said cartridge.
摘要:
Cartridge and method for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample comprising one or more nucleic acid sequences. The cartridge comprises a one or more nucleic acid sequences, and the cartridge includes a generic part and one or more separate application-specific parts, which are connectable to the generic part.