公开(公告)号：US06720449B2

公开(公告)日：2004-04-13

申请号：US09926346

申请日：2002-02-05

申请人： Masanobu Sugawara ,  Akio Fujii ,  Kazumi Okuro ,  Yasuhiro Saka ,  Nobuo Nagashima ,  Kenji Inoue ,  Toshihiro Takeda ,  Koichi Kinoshita ,  Tadashi Moroshima ,  Yoshihide Fuse ,  Yasuyoshi Ueda

发明人： Masanobu Sugawara ,  Akio Fujii ,  Kazumi Okuro ,  Yasuhiro Saka ,  Nobuo Nagashima ,  Kenji Inoue ,  Toshihiro Takeda ,  Koichi Kinoshita ,  Tadashi Moroshima ,  Yoshihide Fuse ,  Yasuyoshi Ueda

IPC分类号： C07D20308

CPC分类号： C07D203/08 ,  C07B2200/07 ,  C07C227/10 ,  C07C227/32 ,  C07C227/42 ,  C07C229/30 ,  C07C303/36 ,  C07D203/20 ,  C07D203/24 ,  C07C311/19 ,  C07C229/26

摘要： An optically active amino acid derivative is produced by N-protecting an optically active 3-haloalanine derivative followed by cyclization, or cyclizing this derivative followed by N-protection to thereby give an optically active N-protected-aziridine-2-carboxylic acid derivative which is protected by a benzenesulfonyl group substituted by nitro at the 2- and/or 4-positions and then treating this product with an organic metal reagent, or by N-protecting an optically active 3-haloalanine derivative to thereby give N-protected-aziridine-2-carboxylic acid which is protected by a benzenesulfonyl group substituted by nitro at the 2- and/or 4-positions and then treating this product with an organic metal reagent. According to this process, natural and unnatural optically active amino acids can be produced from inexpensive materials by using simple procedures.

摘要翻译： 光学活性氨基酸衍生物通过N-保护光学活性3-卤代丙氨酸衍生物进行环化生成，或使该衍生物环化，接着进行N-保护，从而得到光学活性N-保护的氮丙啶-2-羧酸衍生物， 在2-和/或4-位被硝基取代的苯磺酰基保护，然后用有机金属试剂处理该产物，或通过N-保护光学活性3-卤代丙氨酸衍生物，由此得到N-保护的氮丙啶 -2-羧酸，其在2-和/或4-位被硝基取代的苯磺酰基保护，然后用有机金属试剂处理该产物。根据该方法，天然和非天然旋光氨基酸可以是 通过简单的程序从便宜的材料生产。

公开(公告)号：US07109352B2

公开(公告)日：2006-09-19

申请号：US10716430

申请日：2003-11-20

申请人： Masanobu Sugawara ,  Akio Fujii ,  Kazumi Okuro ,  Yasuhiro Saka ,  Nobuo Nagashima ,  Kenji Inoue ,  Toshihiro Takeda ,  Koichi Kinoshita ,  Tadashi Moroshima ,  Yoshihide Fuse ,  Yasuyoshi Ueda

发明人： Masanobu Sugawara ,  Akio Fujii ,  Kazumi Okuro ,  Yasuhiro Saka ,  Nobuo Nagashima ,  Kenji Inoue ,  Toshihiro Takeda ,  Koichi Kinoshita ,  Tadashi Moroshima ,  Yoshihide Fuse ,  Yasuyoshi Ueda

IPC分类号： C07D203/02 ,  C07D203/08

CPC分类号： C07D203/08 ,  C07B2200/07 ,  C07C227/10 ,  C07C227/32 ,  C07C227/42 ,  C07C229/30 ,  C07C303/36 ,  C07D203/20 ,  C07D203/24 ,  C07C311/19 ,  C07C229/26

摘要： An optically active amino acid derivative is produced by N-protecting an optically active 3-haloalanine derivative followed by cyclization, or cyclizing this derivative followed by N-protection to thereby give an optically active N-protected-aziridine-2-carboxylic acid derivative which is protected by a benzenesulfonyl group substituted by nitro at the 2- and/or 4-positions and then treating this product with an organic metal reagent, or by N-protecting an optically active 3-haloalanine derivative to thereby give N-protected-aziridine-2-carboxylic acid which is protected by a benzenesulfonyl group substituted by nitro at the 2- and/or 4-positions and then treating this product with an organic metal reagent. According to this process, natural and unnatural optically active amino acids can be produced from inexpensive materials by using simple procedures.

摘要翻译： 光学活性氨基酸衍生物是通过N-保护光学活性3-卤代丙氨酸衍生物进行环化，或环化该衍生物进行N-保护而得到光学活性N-保护的氮丙啶-2-羧酸衍生物 在2-和/或4-位被硝基取代的苯磺酰基保护，然后用有机金属试剂处理该产物，或通过N-保护光学活性3-卤代丙氨酸衍生物，由此得到N-保护的氮丙啶 -2-羧酸，其在2-和/或4-位被硝基取代的苯磺酰基保护，然后用有机金属试剂处理该产物。 根据该方法，可以通过简单的方法从便宜的材料制备天然和非天然旋光氨基酸。

公开(公告)号：US20050143586A1

公开(公告)日：2005-06-30

申请号：US10716430

申请日：2003-11-20

申请人： Masanobu Sugawara ,  Akio Fujii ,  Kazumi Okuro ,  Yasuhiro Saka ,  Nobuo Nagashima ,  Kenji Inoue ,  Toshihiro Takeda ,  Koichi Kinoshita ,  Tadashi Moroshima ,  Yoshihide Fuse ,  Yasuyoshi Ueda

发明人： Masanobu Sugawara ,  Akio Fujii ,  Kazumi Okuro ,  Yasuhiro Saka ,  Nobuo Nagashima ,  Kenji Inoue ,  Toshihiro Takeda ,  Koichi Kinoshita ,  Tadashi Moroshima ,  Yoshihide Fuse ,  Yasuyoshi Ueda

IPC分类号： C07C227/10 ,  C07C227/32 ,  C07C227/42 ,  C07C229/26 ,  C07C229/30 ,  C07C303/36 ,  C07C311/19 ,  C07D203/08 ,  C07D203/20 ,  C07D203/24 ,  C07D203/16

CPC分类号： C07D203/08 ,  C07B2200/07 ,  C07C227/10 ,  C07C227/32 ,  C07C227/42 ,  C07C229/30 ,  C07C303/36 ,  C07D203/20 ,  C07D203/24 ,  C07C311/19 ,  C07C229/26

摘要： An optically active amino acid derivative is produced by N-protecting an optically active 3-haloalanine derivative followed by cyclization, or cyclizing this derivative followed by N-protection to thereby give an optically active N-protected-aziridine-2-carboxylic acid derivative which is protected by a benzenesulfonyl group substituted by nitro at the 2- and/or 4-positions and then treating this product with an organic metal reagent, or by N-protecting an optically active 3-haloalanine derivative to thereby give N-protected-aziridine-2-carboxylic acid which is protected by a benzenesulfonyl group substituted by nitro at the 2- and/or 4-positions and then treating this product with an organic metal reagent. According to this process, natural and unnatural optically active amino acids can be produced from inexpensive materials by using simple procedures.

摘要翻译： 光学活性氨基酸衍生物通过N-保护光学活性3-卤代丙氨酸衍生物进行环化生成，或使该衍生物环化，接着进行N-保护，从而得到光学活性N-保护的氮丙啶-2-羧酸衍生物， 在2-和/或4-位被硝基取代的苯磺酰基保护，然后用有机金属试剂处理该产物，或通过N-保护光学活性3-卤代丙氨酸衍生物，由此得到N-保护的氮丙啶 -2-羧酸，其在2-和/或4-位被硝基取代的苯磺酰基保护，然后用有机金属试剂处理该产物。 根据该方法，可以通过简单的方法从便宜的材料制备天然和非天然旋光氨基酸。

公开(公告)号：US06281379B1

公开(公告)日：2001-08-28

申请号：US09578446

申请日：2000-05-26

申请人： Akio Fujii ,  Masanobu Sugawara ,  Kenji Inoue

发明人： Akio Fujii ,  Masanobu Sugawara ,  Kenji Inoue

IPC分类号： C07C22900

CPC分类号： C07C227/16 ,  C07B2200/07 ,  C07C227/02 ,  C07C227/18 ,  C07C227/32 ,  C07C315/04 ,  C07C317/28 ,  C07C229/34

摘要： This invention to provide a process for producing an optically active threo-phenylnorstatin derivative which does not require a toxic cyanating agent or a costly reagent, or a complicated procedure, and can be practiced on a commercial scale. This invention is directed to a process for producing a &bgr;-amino-&agr;-hydroxy acid derivative which comprises treating either a &ggr;-amino-&bgr;-keto sulfoxide derivative with a halogenating agent to produce a &ggr;-amino-&agr;-halo-&bgr;-keto sulfoxide derivative, treating the same with an acid and an alcohol to produce a &bgr;-amino-&agr;-keto ester derivative or &bgr;-amino-&agr;-keto acid derivative, and followed by reducing.

摘要翻译： 本发明提供一种不需要有毒的氰化剂或昂贵的试剂的光学活性的苏氨酸苯基抑制素衍生物的制备方法或复杂的方法，并且可以以商业规模实施。本发明涉及一种用于 产生β-氨基-α-羟基酸衍生物，其包括用卤化剂处理γ-氨基-β-酮亚砜衍生物以产生γ-氨基-α-卤代-β-酮亚砜衍生物，用 酸和醇，生成β-氨基-α-酮酯衍生物或β-氨基-α-酮酸衍生物，然后还原。

公开(公告)号：US20050153408A1

公开(公告)日：2005-07-14

申请号：US10496639

申请日：2002-11-28

申请人： Tatsuya Honda ,  Akio Fujii ,  Kenji Inoue ,  Yoshihiko Yasohara ,  Yoshifumi Itagaki ,  Katsuji Maehara ,  Toshihiro Takeda ,  Yasuyoshi Ueda

发明人： Tatsuya Honda ,  Akio Fujii ,  Kenji Inoue ,  Yoshihiko Yasohara ,  Yoshifumi Itagaki ,  Katsuji Maehara ,  Toshihiro Takeda ,  Yasuyoshi Ueda

IPC分类号： C07C213/02 ,  C07C217/74 ,  C07C303/28 ,  C07C309/66 ,  C07C309/73 ,  C12P7/42 ,  C12P7/62

CPC分类号： C12P7/42 ,  C07B2200/07 ,  C07C213/02 ,  C07C303/28 ,  C07C309/66 ,  C07C309/73 ,  C07C217/74

摘要： The present invention is to efficiently and simply prepare an optically active 7-substituted-2-aminotetralin with industrial advantage. In the process, a 7-substituted-2-tetralone or its bisulfite adduct is reduced with a microorganism to an optically active 7-substituted-2-tetralol. Then, a sulfonyl group is introduced to the hydroxy group to form an optically active 7-substituted-2-sulfonyloxytetralin. Then, with inversion of the configuration, a nitrogen substituent is introduced using a nitrogen nucleophile to form an optically active 2,7-substituted tetralin. Furthermore, if necessary, the nitrogen substituent is converted into a non-substituted amino group. Thus, an optically active 7-substituted-2-aminotetralin or its salt is prepared.

摘要翻译： 本发明是有效且简单地制备具有工业优势的光学活性7-取代-2-氨基四氢萘酚。 在此过程中，7-取代-2-四氢萘酮或其亚硫酸氢盐加合物与微生物一起还原成光学活性的7-取代-2-四氢萘酚。 然后，将磺酰基引入羟基以形成光学活性的7-取代-2-磺酰氧基四氢萘酮。 然后，通过配置的倒置，使用氮亲核试剂引入氮取代基以形成光学活性的2,7-取代的四氢化萘。 此外，如果需要，氮取代基转化为未取代的氨基。 因此，制备光学活性的7-取代-2-氨基四氢萘或其盐。

公开(公告)号：US08279298B2

公开(公告)日：2012-10-02

申请号：US12404169

申请日：2009-03-13

申请人： Akio Fujii

发明人： Akio Fujii

IPC分类号： H04N5/225 ,  H04N5/235 ,  H04N5/76

CPC分类号： H04N1/333 ,  H04N1/212 ,  H04N5/23245 ,  H04N5/772 ,  H04N5/781 ,  H04N5/85 ,  H04N5/907 ,  H04N9/7921 ,  H04N9/8042 ,  H04N9/8047 ,  H04N19/115 ,  H04N19/124 ,  H04N19/152 ,  H04N19/154 ,  H04N19/60 ,  H04N19/61 ,  H04N2201/212 ,  H04N2201/33357

摘要： An imaging apparatus includes a signal processing unit that generates moving image data and still image data using image data output from an imaging unit, a moving image coding unit that encodes the moving image data, a still image coding unit that encodes the still image data, a recording unit that records the coded moving and still image data on a recording medium, a setting unit that sets a data rate of the coded moving image data, and a control unit that controls the moving and still image coding units. The control unit controls the moving image coding unit based on the set data rate to adjust the data rate of the moving image data and the still image coding unit based on the set data rate and a recording data rate of the recording medium to adjust an amount of the still image data.

摘要翻译： 一种成像装置，包括：信号处理单元，其使用从成像单元输出的图像数据生成运动图像数据和静止图像数据;运动图像编码单元，对运动图像数据进行编码;静止图像编码单元，对静止图像数据进行编码; 记录单元，其将编码的移动和静止图像数据记录在记录介质上，设置单元，其设置编码的运动图像数据的数据速率;以及控制单元，其控制移动和静止图像编码单元。 控制单元基于设定的数据速率来控制运动图像编码单元，以基于设定的数据速率和记录介质的记录数据速率来调整运动图像数据和静止图像编码单元的数据速率，以调整量 的静止图像数据。

公开(公告)号：US20100054714A1

公开(公告)日：2010-03-04

申请号：US12547113

申请日：2009-08-25

申请人： Akio Fujii

发明人： Akio Fujii

IPC分类号： H04N7/26

CPC分类号： G11B27/005

摘要： An image recording playback apparatus which, when recording moving image data, performs image capture at high-speed read time Dt, records all the captured images, and records a playback rate Ft (Vt), the read time Dt and image valid time St, with the image data, on a recording medium. Then upon playback of moving image data, the image recording playback apparatus plays back the recorded image data within the image valid time St in accordance with the playback rate. The image recording playback apparatus having this configuration can perform playback intended by a user. Further, when sharpness is to be changed, a playback image with different sharpness can be obtained by changing the image valid time St upon playback.

摘要翻译： 一种图像记录播放装置，当记录运动图像数据在高速读取时间Dt进行图像捕获时，记录所有拍摄图像，并记录播放速率Ft（Vt），读取时间Dt和图像有效时间St， 与图像数据一起在记录介质上。 然后，在播放运动图像数据时，图像记录重放装置根据回放速率在图像有效时间St内重放记录图像数据。 具有这种配置的图像记录播放设备可以执行用户想要的播放。 此外，当要改变锐度时，通过在重放时改变图像有效时间St可以获得具有不同清晰度的重放图像。

公开(公告)号：US20090237519A1

公开(公告)日：2009-09-24

申请号：US12404169

申请日：2009-03-13

申请人： Akio Fujii

发明人： Akio Fujii

IPC分类号： H04N5/225 ,  H04N5/228 ,  H04N7/26

CPC分类号： H04N1/333 ,  H04N1/212 ,  H04N5/23245 ,  H04N5/772 ,  H04N5/781 ,  H04N5/85 ,  H04N5/907 ,  H04N9/7921 ,  H04N9/8042 ,  H04N9/8047 ,  H04N19/115 ,  H04N19/124 ,  H04N19/152 ,  H04N19/154 ,  H04N19/60 ,  H04N19/61 ,  H04N2201/212 ,  H04N2201/33357

摘要： An imaging apparatus includes a signal processing unit that generates moving image data and still image data using image data output from an imaging unit, a moving image coding unit that encodes the moving image data, a still image coding unit that encodes the still image data, a recording unit that records the coded moving and still image data on a recording medium, a setting unit that sets a data rate of the coded moving image data, and a control unit that controls the moving and still image coding units. The control unit controls the moving image coding unit based on the set data rate to adjust the data rate of the moving image data and the still image coding unit based on the set data rate and a recording data rate of the recording medium to adjust an amount of the still image data.

摘要翻译： 一种成像装置，包括：信号处理单元，其使用从成像单元输出的图像数据生成运动图像数据和静止图像数据;运动图像编码单元，对运动图像数据进行编码;静止图像编码单元，对静止图像数据进行编码; 记录单元，其将编码的移动和静止图像数据记录在记录介质上，设置单元，其设置编码的运动图像数据的数据速率;以及控制单元，其控制移动和静止图像编码单元。 控制单元基于设定的数据速率来控制运动图像编码单元，以基于设定的数据速率和记录介质的记录数据速率来调整运动图像数据和静止图像编码单元的数据速率，以调整量 的静止图像数据。

公开(公告)号：USD590857S1

公开(公告)日：2009-04-21

申请号：US29318779

申请日：2008-05-28

申请人： Akio Fujii

设计人： Akio Fujii

公开(公告)号：US20090010786A1

公开(公告)日：2009-01-08

申请号：US11885776

申请日：2007-01-25

申请人： Tatsuya Koide ,  Ken Suitou ,  Kazuya Kimura ,  Akio Fujii ,  Akihiko Taketani ,  Masao Iguchi ,  Kenji Mochizuki ,  Shingo Enami

发明人： Tatsuya Koide ,  Ken Suitou ,  Kazuya Kimura ,  Akio Fujii ,  Akihiko Taketani ,  Masao Iguchi ,  Kenji Mochizuki ,  Shingo Enami

IPC分类号： F04B39/12 ,  F04B17/03 ,  F16J15/06

CPC分类号： F04C27/008 ,  F01C21/10 ,  F04C18/0215 ,  F04C27/003 ,  F04C2240/30 ,  F04C2240/808 ,  F16J15/022 ,  F16J15/061 ,  F16J15/062 ,  F16J15/104 ,  F16J15/121 ,  F16J15/122 ,  F16J15/125 ,  H02K5/22 ,  H02K5/225

摘要： An electrically-driven compressor including a housing, an electric motor, a compression mechanism, a cover member, a motor drive circuit, and a sealing member is disclosed. The electric motor is accommodated in the housing. The compression mechanism is accommodated in the housing and operated by the electric motor. The cover member is attached to the housing. The housing and the cover member form an accommodation portion including an accommodation space therein. The motor drive circuit is accommodated in the accommodation space and drives the electric motor. The sealing member is arranged between the housing and the cover member to seal the accommodation space. The sealing member includes an elastic seal portion that comes into close contact with the housing and the cover member. A core sustains the shape of the seal portion in conformance with the circumferential edge of the accommodation space. The core is formed so that at least a circumferential edge part of the core is in conformance with the circumferential edge of the accommodation space. The seal portion is formed integrally with the circumferential edge part of the shape sustaining member by depositing rubber material thereon.

摘要翻译： 公开了一种电动压缩机，包括壳体，电动机，压缩机构，盖构件，马达驱动电路和密封构件。 电动机容纳在壳体中。 压缩机构容纳在壳体中并由电动机操作。 盖构件附接到壳体。 壳体和盖构件形成包括其中的容纳空间的容纳部分。 电机驱动电路容纳在容纳空间中并驱动电动机。 密封构件设置在壳体和盖构件之间以密封容纳空间。 密封构件包括与壳体和盖构件紧密接触的弹性密封部。 核心保持密封部分的形状与容纳空间的圆周边缘一致。 芯部形成为使得至少芯部的周向边缘部分与容纳空间的圆周边缘一致。 密封部分通过在其上沉积橡胶材料与形状维持构件的周边部分一体地形成。