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12 条记录 (耗时 0.016 秒)

    Preparation for percutaneous administration
    1.
    发明授权
    Preparation for percutaneous administration 失效
    经皮给药制剂

    公开(公告)号：US4654209A

    公开(公告)日：1987-03-31

    申请号：US765451

    申请日：1985-08-14

    申请人： Stewart T. Leslie ,  Alan Rhodes ,  Cyril Boroda ,  Alfred Halpern

    发明人： Stewart T. Leslie ,  Alan Rhodes ,  Cyril Boroda ,  Alfred Halpern

    IPC分类号： A61K9/107 ,  A61K31/21 ,  A61K31/79

    CPC分类号： A61K9/107 ,  A61K31/21 ,  Y10S514/947 ,  Y10S514/97

    摘要： A preparation for percutaneous administration of nitroglycerine, said preparation comprising nitroglycerine incorporated in a cream base in an amount not less than about 0.05% by weight based on the total weight of the preparation. The composition may also contain other medicaments, the bioavailability of which is enhanced by the nitroglycerine. The action of the preparation against for example angina may be brought about by having an appropriate amount of nitroglycerine or as additional medicament another medicament active against angina. The preparation may contain an hydroxyalkylcellulose which may provide, in combination with a waxy component in the cream, for example a higher aliphatic alcohol, a prolonged release effect. The preparation has advantages particularly as regards bioavailability over prior uniphasic ointments.

    Processes and Systems For Solvent Extraction of Bitumen From Oil Sands
    2.
    发明申请
    Processes and Systems For Solvent Extraction of Bitumen From Oil Sands 审中-公开
    石油沥青溶剂萃取工艺及系统

    公开(公告)号：US20130001136A1

    公开(公告)日：2013-01-03

    申请号：US13514024

    申请日：2010-12-29

    申请人： Olusola B. Adeyinka ,  Brian C. Speirs ,  Payman Esmaeili ,  Fritz Pierre, JR. ,  Alan Rhodes ,  Werner Glanz ,  Ronald D. Myers

    发明人： Olusola B. Adeyinka ,  Brian C. Speirs ,  Payman Esmaeili ,  Fritz Pierre, JR. ,  Alan Rhodes ,  Werner Glanz ,  Ronald D. Myers

    IPC分类号： C10G1/04 ,  C10C3/08

    CPC分类号： C10G1/04 ,  C10G2300/206 ,  C10G2300/301 ,  C10G2300/4006 ,  C10G2300/44 ,  C10G2300/80 ,  C10G2300/807

    摘要： Processes and systems are described for solvent extraction of bitumen from oil sands. Fines agglomeration is employed to simplify subsequent separation. A high quality bitumen product can be formed, which meets or exceeds downstream processing and pipeline requirements. An embodiment comprises combining a first solvent and a bituminous feed to form an initial slurry, which is optionally separated into fine solids and coarse solids. Slurry solids are agglomerated. A low solids bitumen extract from the agglomerated slurry is mixed with a second solvent having a similar or lower boiling point than the first. The mixture is separated, solvent recovered, and a high grade bitumen product is formed. Exemplary systems comprise a mixbox, agglomerator, separator unit with optional countercurrent washer and deep cone settler, and TSRU. Processes are provided for fractionating a hydrocarbon fluid into heavier and lighter fractions. The lighter fraction may be used in solvent extraction of bitumen.

    摘要翻译： 描述了从油砂中沥青溶剂萃取的方法和系统。 微粒聚集用于简化随后的分离。 可以形成高品质的沥青产品，满足或超过下游加工和管道要求。 一个实施方案包括组合第一溶剂和沥青进料以形成初始浆料，其任选地分离成细固体和粗固体。 泥浆固体聚集。 来自凝聚的浆料的低固体沥青提取物与具有与第一溶剂相似或更低沸点的第二溶剂混合。 分离混合物，回收溶剂，形成高级沥青产物。 示例性系统包括混合箱，附聚器，具有可选的逆流洗涤器和深锥形沉降器的分离器单元和TSRU。 提供了将烃流体分馏成较重和较轻馏分的方法。 较轻馏分可用于沥青的溶剂萃取。

    Method of Treating Organs
    3.
    发明申请
    Method of Treating Organs 审中-公开
    治疗器官的方法

    公开(公告)号：US20130177898A1

    公开(公告)日：2013-07-11

    申请号：US13542488

    申请日：2012-07-05

    申请人： John Brassil ,  Alan Rhodes

    发明人： John Brassil ,  Alan Rhodes

    IPC分类号： A01N1/02

    CPC分类号： A01N1/0294

    摘要： A method of treating tissue, including organs, with electromagnetic energy to decrease the fat content of the tissue comprises the steps of providing a source of electromagnetic energy, and subjecting adipose cells to the source of electromagnetic energy at hypothermic conditions. The tissue may be harvested and in an isolated state, such as being placed in an organ preservation system. Electromagnetic energy between 600 nm to 700 nm is used for treatment. During treatment, target tissue such as a harvested organ is subject to perfusion.

    摘要翻译： 用电磁能处理组织（包括器官）以减少组织的脂肪含量的方法包括提供电磁能源并在低温条件下使脂肪细胞进入电磁能源的步骤。 可以收获组织并处于分离状态，例如放置在器官保存系统中。 使用600nm至700nm之间的电磁能量进行处理。 在治疗期间，靶组织如收获的器官被灌注。

    Percutaneous administration of nitroglycerine
    5.
    发明授权
    Percutaneous administration of nitroglycerine 失效
    经皮给药硝酸甘油

    公开(公告)号：US4322433A

    公开(公告)日：1982-03-30

    申请号：US203481

    申请日：1980-11-03

    申请人： Stewart T. Leslie ,  Alan Rhodes ,  Cyril Boroda ,  Alfred Halpern

    发明人： Stewart T. Leslie ,  Alan Rhodes ,  Cyril Boroda ,  Alfred Halpern

    IPC分类号： A61K9/107 ,  A61K31/21

    CPC分类号： A61K9/107 ,  A61K31/21 ,  Y10S514/947 ,  Y10S514/97

    摘要： A preparation for percutaneous administration of nitroglycerine, said preparation comprising nitroglycerine incorporated in a cream base in an amount not less than about 0.05% by weight based on the total weight of the preparation. The composition may also contain other medicaments, the bioavailability of which is enhanced by the nitroglycerine. The action of the preparation against for example angina may be brought about by having an appropriate amount of nitroglycerine or as additional medicament another medicament active against angina. The preparation may contain an hydroxyalkylcellulose which may provide, in combination with a waxy component in the cream, for example a higher aliphatic alcohol, a prolonged release effect. The preparation has advantages particularly as regards bioavailability over prior uniphasic ointments.

    摘要翻译： 一种用于经皮给药硝酸甘油的制剂，所述制剂包含以不低于制剂总重量的约0.05重量％的量掺入乳膏基质中的硝酸甘油。 组合物还可以含有其它药物，其生物利​​用度由硝酸甘油增强。 制备例如心绞痛的作用可以通过使用适量的硝酸甘油或另外的药物来治疗心绞痛。 该制剂可以含有羟烷基纤维素，其可以与霜中的蜡状组分组合，例如高级脂族醇，延长的释放效果。 该制剂在生物利用度方面特别优于以前的非相软膏。

    Method for the extraction of sesquiterpene lactones
    8.
    发明授权
    Method for the extraction of sesquiterpene lactones 失效
    提取倍半萜内酯的方法

    公开(公告)号：US5384121A

    公开(公告)日：1995-01-24

    申请号：US87672

    申请日：1993-07-08

    申请人： Alan Rhodes

    发明人： Alan Rhodes

    IPC分类号： A61K31/365 ,  A61K31/34 ,  A61K36/00 ,  A61K36/28 ,  C07D493/04 ,  A61K35/78

    CPC分类号： C07D493/04 ,  A61K36/28

    摘要： The present invention relates to a method for the extraction of sesquiterpene lactones from the plant Tanacetum parthenium specifically using polar organic solvents and the use of such extracts in pharmaceutical products. It has been found that by utilization of an extraction procedure in accordance with the current invention, a significantly greater amount of the sesquiterpene lactone parthenolide is extracted from Tanacetum parthenium than is the case when using petroleum spirit as the primary extractant, the solvent usually used in previous studies.

    摘要翻译： PCT No.PCT / GB92 / 00036 Sec。 371日期：1993年7月8日 102（e）日期1993年7月8日PCT提交1992年1月8日PCT公布。 第WO92 / 11857号公报 日本1992年7月23日。本发明涉及一种特异性使用极性有机溶剂从植物丹参醇中提取倍半萜内酯的方法，以及在药品中使用这些提取物。 已经发现，通过利用根据本发明的提取方法，与使用石油醚作为主要萃取剂的情况相比，从Tanacetum铼中提取显着更多量的倍半萜内酯单酚酯，溶剂通常用于 以前的研究。