摘要:
Disclosed is a photographic element comprising a light-sensitive silver halide emulsion layer having associated therewith a cyan dye-forming coupler represented by Formula (I): wherein: each R1 and R3 is an independently selected substituent, m is 0 to 5, and p is 0 to 2; X is hydrogen or a coupling-off group; W and W2 represent the atoms necessary to complete rings; and R2 is an alkyl or aryl group. The element provides desirable hue properties and ease of synthesis.
摘要:
Disclosed is a photographic element complising a light sensitive silver halide emulsion layer having associated therewith a cyan dye forming coupler having Formula (I): wherein R1 and R3 independently represent hydrogen or an alkyl group; R2 represents a carbocyclic or heterocyclic aromatic group; n represents 1, 2, or 3; each X is an independently selected substituent where at least one X located at a position of the phenyl ring meta or para to the sulfonyl group and is either an alkoxy group having a branched carbon or an aiyloxy group; and Z represents hydrogen or a group that can be split off by the reaction of the coupler with an oxidized color-developing compound; provided that the substituents of the compound of formula (I) are selected so that the compound has a melting point of 160° C. or less. The element provides improved phase stability during manufacturing while exhibiting satisfactory hue and dye light stability.
摘要:
Compounds having the structural formula ##STR1## which inhibit the enzymatic activity of proteolytic enzymes, and processes for preparation thereof, method of use thereof in treatment of degenerative diseases and pharmaceutical compositions thereof are disclosed.
摘要:
Certain methanol soluble ortho-benzo or -naphthoquinones are useful electron transfer agents. They are particularly useful in the detection of cells in urine.
摘要:
Disclosed is a silver halide photographic element comprising a support bearing a light sensitive silver halide emulsion layer having associated therewith a cyclic azole dye forming coupler and a stabilizer combination comprising:i) a compound having the following Formula I: ##STR1## and ii) a compound having the following Formula S: ##STR2## wherein R.sub.3 is an alkyl, alkenyl, or aryl group; R.sub.5 is an alkyl group; and R.sub.4 and R.sub.6 are substituents; m is an integer of 0 to 5; and n is an integer of 0 to 4.
摘要:
4-R.sup.4 -R.sup.5 -2-Saccharinylmethyl aryl carboxylates, useful in the treatment of degenerative diseases, are prepared by reacting a 4-R.sup.4 -R.sup.5 -2-halomethylsaccharin with an arylcarboxylic acid in the presence of an acid-acceptor.
摘要:
Novel 2-substituted saccharins which inhibit the enzymatic activity of proteolytic enzymes, are useful in the treatment of degenerative diseases and have the formula 0010wherein:L is --O--, --S--, --SO-- or --SO.sub.2 --; m and n are each independently 0 or 1; R.sub.1 is halo, lower-alkanoyl, 1-oxophenalenyl, phenyl or substituted phenyl, heterocyclyl or substitued heterocyclyl or, when L is --O-- and n is 1, cycloheptatrienon-2-yl or, when L is --S-- and n is 1, cyano or lower-alkoxythiocarbonyl or, when L is --SO.sub.2 -- and n is 1, lower-alkyl or trifluoromethyl; R.sub.2 is hydrogen, lower-alkoxycarbonyl, phenyl or phenylthio; and R.sub.3 and R.sub.4 are each hydrogen or various substituents and processes for preparation and pharmaceutical compositions and method of use thereof are disclosed.
摘要:
Certain reducible compounds are useful in analytical compositions, elements and methods, e.g. for assays of bacterial cells. These compounds comprise a moiety which provides a detectable species (e.g. a dye) when released from the compound in an environment of pH 9 or less (i.e. physiological pH). Structurally, the reducible compounds are aromatic derivatives or quinones having suitable substituents which promote varying amounts of moiety release at physiological pH. When reduced at about pH 7, the preferred compounds release at least 50% of the available detectable species within 30 minutes.
摘要:
Novel 2-substituted saccharins which inhibit the enzymatic activity of proteolytic enzymes, are useful in the treatment of degenerative diseases and have the formula ##STR1## wherein: L is --O--, --S--, --SO-- or --SO.sub.2 --;m and n are each independently 0 or 1;R.sub.1 is halo, lower-alkanoyl, 1-oxophenalenyl, phenyl or substituted phenyl, heterocyclyl or substituted heterocyclyl or, when L is --O-- and n is 1, cycloheptatrienon-2-yl or, when L is --S-- and n is 1, cyano or lower-alkoxythiocarbonyl or, when L is --SO.sub.2 -- and n is 1, lower-alkyl or trifluoromethyl;R.sub.2 is hydrogen, lower-alkoxycarbonyl, phenyl or phenylthio; andR.sub.3 and R.sub.4 are each hydrogen or various substituents and processes for preparation and pharmaceutical compositions and method of use thereof are disclosed.
摘要:
Certain reducible aromatic and quinone compounds having bulky groups on the carbamate nitrogen atom have improved stability to light. These compounds are useful in analytical compositions, elements and methods, e.g. for assays of bacterial cells. These compounds have suitable substituents that promote the release of phenalenone or benzphenalenone fluorescent dyes at physiological pH.