摘要:
The invention relates to acarviosyl transferase from actinomycetes, mainly from Actinoplanes sp. SE 50/110 and its mutants, to a process for isolating, purifying and characterizing the enzyme, to the isolation and characterization of the acbD gene encoding the acarviosyl transferase, to the expression of the acarviosyl transferase in a heterologous host organism, to the use of the acarviosyl transferase for converting acarbose minor constituents into acarbose or for preparing acarbose homologues, to the use of the acarviosyl transferase in acarbose purification, and also to the preparation of production mutants in which formation of minor constituents is reduced by means of inactivation of the acarviosyl transferase gene.
摘要翻译:本发明涉及来自放线菌的主要来自Actinoplanes sp。的acarviosyl转移酶。 SE 50/110及其突变体,用于分离,纯化和表征酶的过程,分离和表征编码α-乙酰氧基转移酶的acbD基因到异源宿主生物体中的阿卡非糖转移酶的表达,使用 的阿卡波糖转移酶用于将阿卡波糖次要成分转化成阿卡波糖或用于制备阿卡波糖同系物,以及在阿卡波糖纯化中使用阿卡波糖转移酶,以及制备生产突变体,其中通过灭活 阿维生素转移酶基因。
摘要:
A shear for cutting profile and/or flat and/or solid-section steel has at least one vertical frame plate having a front face and a back face and formed with a throughgoing workpiece window, at least one fixed blade carried on the plate at the window, a working slide displaceable on the back face of the frame plate and carrying a movable blade passing past the fixed blade on movement of the slide on the frame plate, a generally flat holddown plate carrying a holddown element, and a pivot supporting the holddown plate on the frame plate for movement parallel to the frame plate and about a horizontal axis generally perpendicular to the frame plate between a raised position and a lowered position, and for movement also about a vertical axis between a use position lying against the front face of the frame plate and a service position extending transversely therefrom. Clamps secure the holddown plate in the use position against the frame plate with limited pivoting about the horizontal axis only. An actuator braced between the frame plate and the holddown plate in the use position of same pivots same limitedly about the horizontal axis and thereby presses the holddown element against a workpiece engaged through the window.
摘要:
A method and device for reading out a fiber gyroscope based on the concept of determining, by gating the light signal for particular time intervals, only one particular phase section of the read-out signal of a photodetector of the fiber optic gyroscope modulated with a periodic function. Further phase sections are determined in sequence and cyclically in the same manner so that the entire photodetector signal is detected after one full cycle. Signals associated with individual phase sections are averaged separately and processed to obtain a rotation rate-proportional signal. The read-out signals can also be processed so that a control signal for deviation of the phase modulator is obtained and/or the gyroscope scale factor is stabilized.
摘要:
Peptides having essentially the sequence of bovine pancreatic trypsin inhibitor (aprotinin) wherein one or more of the amino acids at positions 15, 16, 17, 18, 34, 39 and 52 are replaced by any naturally occurring amino acid produced by recombinant DNA technology, process, expression vector and recominant host therefor and pharmaceutical use thereof. Such peptides being useful as therapeutic agents in diseases connected with the presence of excessive amounts of proteinases.
摘要:
Peptides having essentially the sequence of bovine pancreatic trypsin inhibitor (aprotinin) wherein one or more of the amino acids at positions 15, 16, 17, 18, 34, 39 and 52 are replaced by any naturally occurring amino acid produced by recombinant DNA technology, process, expression vector and recominant host therefor and pharmaceutical use thereof. Such peptides being useful as therapeutic agents in diseases connected with the presence of excessive amounts of proteinases.
摘要:
A method and apparatus for reading out angular rates by means of a passive optical resonator provides for the generation of three component light beams individually tuned to distinct resonator modes. One component light beam is radiated into the resonator in the opposite direction to the two other component light beams. By means of an evaluating logic, differences are formed between the counterrotating light beams and the differences weighted and subtracted from each other to provide angular rate. The optical length of the resonator, and, thus, temperature are available as a weighted sum of the differences. Temperature drift may be eliminated from angular rate measurements by compensation according to the invention.
摘要:
A process is disclosed for sterilising ambient air conducted in an air duct (401), as well as a use of a device for breaking down gaseous hydrocarbon emissions in order to sterilise ambient air conducted in an air duct (104), and a device for sterilising ambient air conducted in an air duct (401). Ambient air is supplied to the air duct (401) of an UV unit (403) for irradiation with UV radiation, and the thus pre-purified ambient air is supplied to a downstream ionization unit (407) arranged in the air duct and in which the ambient air is ionised.
摘要:
Microbially produced aprotinin and aprotinin homologs used for treating patients suffering from an excess release of pancreatic elastase, serum elastase or leukocyte elastase.
摘要:
A lower tool support for a stamping machine or the like having a lower frame and a tool saddle with a saddle plate, movably disposed on the saddle surface of the lower frame, with adjusting devices for the adjustment of the tool saddle in relation to the lower frame in the plane of the saddle surface and an arresting device for fixing the tool saddle on the lower frame being provided, the saddle plate of the tool saddle having at least one lower flange and the arresting device having at least one fastening flange formfittingly overlapping the lower flange, the fastening flange in the plane of the saddle surface having an exactly determined relative position in respect to the lower frame, thus securing the saddle plate against vertical lifting from the saddle surface. In the installation of the tool saddle this lower tool support has the vertical distance of the fastening flange of the arresting device from the saddle surface of the lower frame exactly predetermined and is somehwat larger than the thickness of the lower flange of the saddle plate.
摘要:
A metalworking machine such as a punch or shear has a pair of substantially parallel and spaced-apart frame plates which are mounted fixedly relative to each other and which flank a vertically displaceable work slide formed at its upper edge with a T-shaped notch. A hydraulic ram is fixed to the plates and has a flat T-shaped piston rod receivable in the T-shaped notch of the slide for force transmission between the piston and the slide. The piston and slide can be separated from each other by relative lateral displacement perpendicular to the plane of the slide.