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    COMPOSITE DETECTION DEVICES HAVING IN-LINE DESALTING AND METHODS OF MAKING THE SAME
    7.
    发明申请
    COMPOSITE DETECTION DEVICES HAVING IN-LINE DESALTING AND METHODS OF MAKING THE SAME 有权
    具有在线脱盐剂的复合物检测装置及其制备方法

    公开(公告)号：US20090142825A1

    公开(公告)日：2009-06-04

    申请号：US11947224

    申请日：2007-11-29

    申请人： Anthony John Murray ,  Anping Zhang ,  Rui Chen

    发明人： Anthony John Murray ,  Anping Zhang ,  Rui Chen

    IPC分类号： C12M1/34 ,  G03C5/60

    CPC分类号： G01N33/54373 ,  B01L3/5027 ,  B01L3/502753 ,  Y10S977/904 ,  Y10S977/92 ,  Y10S977/958

    摘要： A composite detection device having in-line desalting is provided. The composite detection device comprises a membrane configured for desalting at least a portion of an analyte stream, and a nanostructure for detecting a bio-molecule or a bio-molecule interaction, wherein the nanostructure and the membrane are arranged such that an analyte stream desalted at least in part by the membrane is detected by the nanostructure. A bio-sending detection system having the composite detection device and method of fabrication of the composite detection device are also provided.

    摘要翻译： 提供具有直列脱盐的复合检测装置。 复合检测装置包括被配置用于对分析物流的至少一部分进行脱盐的膜和用于检测生物分子或生物分子相互作用的纳米结构，其中纳米结构和膜被布置成使得分析物流在 至少部分由膜被纳米结构检测。 还提供了具有复合检测装置和复合检测装置的制造方法的生物发送检测系统。

    NANOSTRUCTURED DEVICES FOR DETECTING AND ANALYZING BIOMOLECULES
    8.
    发明申请
    NANOSTRUCTURED DEVICES FOR DETECTING AND ANALYZING BIOMOLECULES 有权
    用于检测和分析生物分子的纳米结构设备

    公开(公告)号：US20160202254A1

    公开(公告)日：2016-07-14

    申请号：US11947834

    申请日：2007-11-30

    申请人： An-Ping Zhang ,  Anthony John Murray ,  Rui Chen

    发明人： An-Ping Zhang ,  Anthony John Murray ,  Rui Chen

    IPC分类号： G01N33/543 ,  G01N27/414

    CPC分类号： G01N33/54373 ,  B82Y15/00 ,  B82Y40/00 ,  G01N27/327 ,  G01N27/4145 ,  G01N27/4146 ,  G01N33/545

    摘要： A biosensing FET device, comprising a plurality of nanostructured SOI channels, that is adapted to operate in solutions having a high ionic strength and provides improves sensitivity and detection. Generally, the biosensing device comprises an underlying substrate layer, an insulator and a semiconductor layer and a plurality of channels in the semiconductor layer comprising a plurality of whole or partially formed nanopores in the channels.

    摘要翻译： 一种生物传感FET器件，包括多个纳米结构SOI沟道，其适于在具有高离子强度的溶液中操作并且提供灵敏度和检测。 通常，生物传感装置包括下面的基底层，绝缘体和半导体层，以及半导体层中的多个通道，其在通道中包括多个整体或部分形成的纳米孔。

    Electrophoresis system and method
    10.
    发明授权
    Electrophoresis system and method 失效
    电泳系统及方法

    公开(公告)号：US07740748B2

    公开(公告)日：2010-06-22

    申请号：US12258657

    申请日：2008-10-27

    申请人： Wei-Cheng Tian ,  Shashi Thutupalli ,  Li Zhu ,  Anthony John Murray ,  Erin Jean Finehout ,  Jun Xie

    发明人： Wei-Cheng Tian ,  Shashi Thutupalli ,  Li Zhu ,  Anthony John Murray ,  Erin Jean Finehout ,  Jun Xie

    IPC分类号： G01N27/447 ,  G01N27/453

    CPC分类号： B01D57/02 ,  B01L3/502715 ,  G01N27/44743

    摘要： Electrophoresis systems and methods comprise an electrophoresis device, wherein the electrophoresis device comprises a loading channel, an injection channel, and a separation channel. The loading channel is in fluid communication with a first and second sample port. The injection channel is connected to the loading channel to form a first intersection. The separation channel is connected to the injection channel to form a second intersection and in fluid communication with a first and second reservoir, and wherein the injection channel is in fluid communication with a third reservoir. The electrophoresis system further comprises electrodes coupled to the first sample port and the third reservoir, and the first reservoir and the second reservoir, respectively, that are adapted to move the sample into the loading channel towards the third reservoir and form a sample plug in the second intersection, and to further move the sample plug into the separation channel towards the second reservoir.

    摘要翻译： 电泳系统和方法包括电泳装置，其中电泳装置包括装载通道，注射通道和分离通道。 装载通道与第一和第二采样端口流体连通。 注入通道连接到装载通道以形成第一交叉。 分离通道连接到注入通道以形成第二交叉并且与第一和第二储存器流体连通，并且其中注入通道与第三储存器流体连通。 电泳系统还包括分别耦合到第一样品端口和第三储存器的电极，以及分别适于将样品移动到装载通道中的第一储存器和第二储存器，以朝向第三储存器形成样品塞 并且将样品塞进一步朝向第二储存器移动到分离通道中。