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15 条记录 (耗时 0.022 秒)

    System for hybrid position and force control
    2.
    发明授权
    System for hybrid position and force control 失效
    混合位置和力控制系统

    公开(公告)号：US5276390A

    公开(公告)日：1994-01-04

    申请号：US60681

    申请日：1993-05-10

    申请人： William D. Fisher ,  M. Shahid Mujtaba

    发明人： William D. Fisher ,  M. Shahid Mujtaba

    IPC分类号： B25J9/16 ,  G05B19/42

    CPC分类号： B25J9/1633

    摘要： A hybrid position and force control system for a robotic manipulator. A displacement error signal of an end effector such as a robotic hand is multiplied by a pseudo-inverse of a matrix product of a selection matrix and a Jacobian matrix to provide a joint displacement error signal in the coordinates of the various joints of the manipulator. The system may be tuned for obstacle avoidance and the like by means of a joint tuning signal having displacement and force components each produced by multiplying a user-provided tuning signal by a matrix difference between an identity matrix and a matrix product of a pseudo-inverse of the Jacobian mattrix and the Jacobian matrix.

    摘要翻译： 一种用于机器人操纵器的混合位置和力控制系统。 诸如机器人手的末端执行器的位移误差信号乘以选择矩阵和雅可比矩阵的矩阵乘积的伪逆，以在机械手的各个关节的坐标中提供关节位移误差信号。 可以通过具有位移和力分量的联合调谐信号来调整系统以避免障碍物等等，每个位移和力分量通过将用户提供的调谐信号乘以单位矩阵和伪逆矩阵的矩阵乘积之间的矩阵差而产生 的雅可比垫片和雅可比矩阵。

    Ion source sample plate illumination system
    3.
    发明授权
    Ion source sample plate illumination system 有权
    离子源样品板照明系统

    公开(公告)号：US07435951B2

    公开(公告)日：2008-10-14

    申请号：US11148786

    申请日：2005-06-08

    申请人： Jean-Luc Truche ,  Gregor T. Overney ,  William D. Fisher ,  Richard P. Tella

    发明人： Jean-Luc Truche ,  Gregor T. Overney ,  William D. Fisher ,  Richard P. Tella

    IPC分类号： B01D59/44 ,  H01J49/00

    CPC分类号： H01J49/0418 ,  G03B15/07 ,  H01J49/0004

    摘要： The invention provides a mass spectrometry system ion source containing a sample plate and an illumination device that is configured to produce a light beam that contacts the sample plate surface to define a grazing angle between the light beam and the sample plate surface. The ion source may also contain an imaging device, e.g., a CCD or CMOS camera or the like, for viewing the area. In one embodiment, the imaging device may be connected to a display, e.g., a video monitor. Methods and mass spectrometry systems empliying the ion source are also provided.

    摘要翻译： 本发明提供一种包含样品板和照明装置的质谱系统离子源，其被配置为产生与样品板表面接触以限定光束和样品板表面之间的掠射角的光束。 离子源还可以包含用于观察该区域的成像装置，例如CCD或CMOS照相机等。 在一个实施例中，成像装置可以连接到显示器，例如视频监视器。 还提供了使用离子源的方法和质谱系统。

    System and method of lens placement
    4.
    发明授权
    System and method of lens placement 有权
    透镜放置的系统和方法

    公开(公告)号：US07433585B2

    公开(公告)日：2008-10-07

    申请号：US11273990

    申请日：2005-11-15

    申请人： Richard P. Tella ,  William D. Fisher

    发明人： Richard P. Tella ,  William D. Fisher

    IPC分类号： G03B3/00 ,  G03B17/00

    CPC分类号： G03B43/00 ,  H04N5/2254

    摘要： A lens-placement system in accordance with the invention includes an imaging system having an imaging camera to capture an image of at least a portion of an image sensor module that is located in a fixed-focus camera. The captured image is used for placement of a lens in the fixed-focus camera.

    摘要翻译： 根据本发明的透镜放置系统包括成像系统，该成像系统具有成像照相机以捕获位于定焦相机中的图像传感器模块的至少一部分的图像。 拍摄的图像用于将固定焦距相机中的透镜放置。

    Apparatus for deposition and inspection of chemical and biological fluids
    5.
    发明授权
    Apparatus for deposition and inspection of chemical and biological fluids 失效
    用于沉积和检查化学和生物流体的装置

    公开(公告)号：US06689319B1

    公开(公告)日：2004-02-10

    申请号：US09429895

    申请日：1999-10-29

    申请人： William D. Fisher ,  Henrique A. S. Martins ,  Peter G. Webb

    发明人： William D. Fisher ,  Henrique A. S. Martins ,  Peter G. Webb

    IPC分类号： G01N3510

    CPC分类号： B41J29/393 ,  B01J19/0046 ,  B01J2219/00351 ,  B01J2219/00378 ,  B01J2219/00527 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00659 ,  B01J2219/00693 ,  B01J2219/00722 ,  B01J2219/00725 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14 ,  G01N21/95607

    摘要： An apparatus and method are provided for producing and inspecting a plurality of deposited features in a pattern on a portion of a substrate surface, as in an oligonucleotide array. The apparatus comprises a printhead for depositing a fluid to form the array of features on the substrate surface and a camera for imaging the deposited features. The apparatus also comprises a printhead controller for positioning and activating the inkjet printhead to deposit the array features. The camera, e.g., a digital line scan camera, is controlled by a camera controller such that the camera acquires images corresponding to substantially only the portion of the surface on which features should have been deposited. The camera and printhead are preferably situated such that an induced movement of the printhead relative to the substrate results in a substantially identical corresponding movement of the camera. Optionally, the apparatus further comprises means for comparing an image acquired by the camera with a predetermined standard to produce a signal.

    摘要翻译： 提供了一种用于在衬底表面的一部分上以图案形式生产和检查多个沉积特征的装置和方法，如寡核苷酸阵列中那样。 该装置包括用于沉积流体以形成衬底表面上的特征阵列的打印头和用于对沉积的特征进行成像的照相机。 该装置还包括用于定位和启动喷墨打印头以沉积阵列特征的打印头控制器。 照相机，例如数字线扫描照相机，由照相机控制器控制，使得照相机获取对应于基本上只有特征应该已经被沉积的表面部分的图像。 相机和打印头优选地被定位成使得打印头相对于基板的感应运动导致相机的基本上相同的相应运动。 可选地，该装置还包括用于将由照相机获取的图像与预定标准进行比较以产生信号的装置。

    Biopolymer array inspection
    6.
    发明授权
    Biopolymer array inspection 失效
    生物聚合物阵列检查

    公开(公告)号：US06589739B2

    公开(公告)日：2003-07-08

    申请号：US09772842

    申请日：2001-01-29

    申请人： William D. Fisher

    发明人： William D. Fisher

    IPC分类号： C12Q168

    CPC分类号： B01J19/0046 ,  B01J2219/00351 ,  B01J2219/00378 ,  B01J2219/00527 ,  B01J2219/00529 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00608 ,  B01J2219/00626 ,  B01J2219/00659 ,  B01J2219/00704 ,  B01J2219/00707 ,  B01J2219/00722 ,  C40B40/06

    摘要： A method of fabricating a biopolymer array, and an apparatus which can execute the method, droplets of fluid carrying the biopolymer or a biomonomer are deposited onto a front side of a transparent substrate. Light is directed through the substrate from the front side, back through a substrate back side and a first set of deposited droplets on the first side to an image sensor. The substrate may be mounted by means of a chuck with parallel channels, and a scanning operation of a droplet dispensing head, light source, and sensor conducted in unison in the direction of the channels.

    摘要翻译： 一种制造生物聚合物阵列的方法，以及可执行该方法的装置，将携带生物聚合物或生物体的流体液滴沉积在透明基底的正面上。 光通过基板从前侧引导通过基板背面，并将第一组沉积的液滴从第一侧引导到图像传感器。 可以通过具有平行通道的卡盘来安装基板，以及在通道的方向上一致地进行的液滴分配头，光源和传感器的扫描操作。

    Biopolymer array inspection
    7.
    发明授权
    Biopolymer array inspection 失效
    生物聚合物阵列检查

    公开(公告)号：US06232072B1

    公开(公告)日：2001-05-15

    申请号：US09419447

    申请日：1999-10-15

    申请人： William D. Fisher

    发明人： William D. Fisher

    IPC分类号： C12Q168

    CPC分类号： B01J19/0046 ,  B01J2219/00351 ,  B01J2219/00378 ,  B01J2219/00527 ,  B01J2219/00529 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00608 ,  B01J2219/00626 ,  B01J2219/00659 ,  B01J2219/00704 ,  B01J2219/00707 ,  B01J2219/00722 ,  C40B40/06

    摘要： A method of fabricating a biopolymer array, and an apparatus which can execute the method. droplets of fluid carrying the biopolymer or a biomonomer are deposited onto a front side of a transparent substrate. Light is directed through the substrate from the front side, back through a substrate back side and a first set of deposited droplets on the first side to an image sensor. The substrate may be mounted by means of a chuck with parallel channels, and a scanning operation of a droplet dispensing head, light source, and sensor conducted in unison in the direction of the channels.

    摘要翻译： 制造生物聚合物阵列的方法，以及可以执行该方法的装置。 携带生物聚合物或生物体的流体液滴沉积在透明基底的正面上。 光通过基板从前侧引导通过基板背面，并将第一组沉积的液滴从第一侧引导到图像传感器。 可以通过具有平行通道的卡盘来安装基板，以及在通道的方向上一致地进行的液滴分配头，光源和传感器的扫描操作。

    Chemical array fabrication errors
    9.
    发明授权
    Chemical array fabrication errors 失效
    化学阵列制造误差

    公开(公告)号：US07101508B2

    公开(公告)日：2006-09-05

    申请号：US10210126

    申请日：2002-07-31

    申请人： Allen C. Thompson ,  William D. Fisher ,  Michael P. Caren

    发明人： Allen C. Thompson ,  William D. Fisher ,  Michael P. Caren

    IPC分类号： B32B5/02 ,  G01N15/06 ,  G01N1/10 ,  B01L3/02 ,  G06K9/00

    CPC分类号： B01J19/0046 ,  B01J2219/00529 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00637 ,  B01J2219/00691 ,  B01J2219/00693 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01L3/0241 ,  C40B40/06 ,  C40B40/10 ,  G01N35/1011 ,  G01N2035/00158 ,  Y10T436/2575

    摘要： A method of fabricating an addressable array of chemical probes at respective feature locations on a substrate surface. The method may use a deposition apparatus with a substrate unit which includes the substrate and with a drop deposition unit which includes a drop deposition head. Such an apparatus when operated according to a target drive pattern based on nominal operating parameters of the apparatus provides the probes on the substrate surface in the target array pattern. The method may include depositing at least one drop from the head unit onto the substrate surface. A fiducial on the substrate unit is optionally viewed from a sensor. A deposited drop on the substrate surface is viewed from a sensor. An actual position of the viewed deposited drop may be determined relative to a fiducial on the substrate unit, based on the views of the fiducial and deposited drop. An error is determined based on any difference between the actual and target positions. Alternatively, an error for one or more deposition units may be determined based on a statistical difference between the actual and target positions of a set of multiple drops deposited from each deposition unit. The deposition apparatus is operated to deposit further drops from the head unit onto the substrate surface at feature locations while moving at least one of the substrate unit or head unit with respect to the other, so as to fabricate the array. Apparatus and computer program products are also provided.

    摘要翻译： 一种在衬底表面上的相应特征位置处制造可寻址的化学探针阵列的方法。 该方法可以使用具有衬底单元的沉积设备，该衬底单元包括衬底以及包括滴沉积头的液滴沉积单元。 当根据设备的标称操作参数根据目标驱动模式操作时，这种装置在靶阵列图案的基板表面上提供探针。 该方法可以包括将至少一个液滴从头单元沉积到基底表面上。 可选地从传感器观察衬底单元上的基准。 从传感器观察衬底表面上的沉积液滴。 所观察的沉积液滴的实际位置可以基于基准和沉积液滴的视图相对于基底单元上的基准来确定。 根据实际和目标职位之间的差异确定错误。 或者，可以基于从每个沉积单元沉积的一组多滴的实际位置和目标位置之间的统计差异来确定一个或多个沉积单元的误差。 操作沉积设备以在特征位置将更多的液滴从头单元沉积到衬底表面上，同时相对于另一个移动衬底单元或头单元中的至少一个，以便制造阵列。 还提供仪器和计算机程序产品。