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公开(公告)号：US20080200341A1
公开(公告)日：2008-08-21
申请号：US12113388
申请日：2008-05-01
IPC分类号： C40B30/00
CPC分类号： C12Q1/6837 , B01J2219/00333 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00659 , B01J2219/00675 , B01J2219/00677 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01L3/508 , B01L2200/0689 , B01L2300/0636 , B01L2300/0822 , B82Y30/00
摘要： Devices and methods for performing an array assay are provided. Embodiments of the subject array assay devices include (1) a base, (2) a cover, and (3) a clamping member for holding the cover to the base, wherein when the cover is operatively held to the base about a structure that includes an array assembly spaced-apart from a backing element, the array assembly and the backing element are deflected to substantially the same curvature. Embodiments of the subject methods include contacting a sample with a backing element and placing the backing element supported sample in contact with an array assembly to form a structure that includes the backing element and array assembly. The structure is then held together using a subject array assay device and the array substrate and the backing element are deflected to substantially the same curvature.
摘要翻译： 提供了用于进行阵列测定的装置和方法。 本发明的阵列测定装置的实施例包括（1）底座，（2）盖子和（3）用于将盖子保持在基座上的夹紧构件，其中当盖子围绕包括 与背衬元件间隔开的阵列组件，阵列组件和背衬元件被偏转到基本上相同的曲率。 本发明方法的实施方案包括将样品与背衬元件接触并将支撑元件支撑的样品与阵列组件接触以形成包括背衬元件和阵列组件的结构。 然后使用主题阵列测定装置将结构保持在一起，并且阵列基板和背衬元件被偏转到基本上相同的曲率。
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公开(公告)号：US07101508B2
公开(公告)日：2006-09-05
申请号：US10210126
申请日：2002-07-31
CPC分类号： B01J19/0046 , B01J2219/00529 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00637 , B01J2219/00691 , B01J2219/00693 , B01J2219/00722 , B01J2219/00725 , B01L3/0241 , C40B40/06 , C40B40/10 , G01N35/1011 , G01N2035/00158 , Y10T436/2575
摘要： A method of fabricating an addressable array of chemical probes at respective feature locations on a substrate surface. The method may use a deposition apparatus with a substrate unit which includes the substrate and with a drop deposition unit which includes a drop deposition head. Such an apparatus when operated according to a target drive pattern based on nominal operating parameters of the apparatus provides the probes on the substrate surface in the target array pattern. The method may include depositing at least one drop from the head unit onto the substrate surface. A fiducial on the substrate unit is optionally viewed from a sensor. A deposited drop on the substrate surface is viewed from a sensor. An actual position of the viewed deposited drop may be determined relative to a fiducial on the substrate unit, based on the views of the fiducial and deposited drop. An error is determined based on any difference between the actual and target positions. Alternatively, an error for one or more deposition units may be determined based on a statistical difference between the actual and target positions of a set of multiple drops deposited from each deposition unit. The deposition apparatus is operated to deposit further drops from the head unit onto the substrate surface at feature locations while moving at least one of the substrate unit or head unit with respect to the other, so as to fabricate the array. Apparatus and computer program products are also provided.
摘要翻译： 一种在衬底表面上的相应特征位置处制造可寻址的化学探针阵列的方法。 该方法可以使用具有衬底单元的沉积设备，该衬底单元包括衬底以及包括滴沉积头的液滴沉积单元。 当根据设备的标称操作参数根据目标驱动模式操作时，这种装置在靶阵列图案的基板表面上提供探针。 该方法可以包括将至少一个液滴从头单元沉积到基底表面上。 可选地从传感器观察衬底单元上的基准。 从传感器观察衬底表面上的沉积液滴。 所观察的沉积液滴的实际位置可以基于基准和沉积液滴的视图相对于基底单元上的基准来确定。 根据实际和目标职位之间的差异确定错误。 或者，可以基于从每个沉积单元沉积的一组多滴的实际位置和目标位置之间的统计差异来确定一个或多个沉积单元的误差。 操作沉积设备以在特征位置将更多的液滴从头单元沉积到衬底表面上，同时相对于另一个移动衬底单元或头单元中的至少一个，以便制造阵列。 还提供仪器和计算机程序产品。
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公开(公告)号：US5407134A
公开(公告)日：1995-04-18
申请号：US986225
申请日：1992-12-07
申请人： Allen C. Thompson , Max H. Parks
发明人： Allen C. Thompson , Max H. Parks
CPC分类号： A01M7/0092 , A01C23/042
摘要： A liquid distributor having a pair of variable displacement pumps driven by a single electric motor, the rotation speed of which is determined by a voltage from a controller in response to a predetermined ground speed and application rate which mixes a chemical with water in a desired proportion and delivers a solution to be directed into an open furrow just prior to the furrow being covered with dirt.
摘要翻译： 一种液体分配器，其具有由单个电动机驱动的一对可变排量泵，其旋转速度由来自控制器的电压根据预定的地面速度和施加速率确定，所述预定地面速度和施加速率将化学品与水以期望的比例混合 并且在沟槽被污垢覆盖之前，提供一种解决方案来引导到开放的沟槽中。
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公开(公告)号：US07468160B2
公开(公告)日：2008-12-23
申请号：US10729606
申请日：2003-12-05
CPC分类号： C12Q1/6837 , B01J2219/00333 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00659 , B01J2219/00675 , B01J2219/00677 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01L3/508 , B01L2200/0689 , B01L2300/0636 , B01L2300/0822 , B82Y30/00
摘要： Devices and methods for performing an array assay are provided. Embodiments of the subject array assay devices include (1) a base, (2) a cover, and (3) a clamping member for holding the cover to the base, wherein when the cover is operatively held to the base about a structure that includes an array assembly spaced-apart from a backing element, the array assembly and the backing element are deflected to substantially the same curvature. Embodiments of the subject methods include contacting a sample with a backing element and placing the backing element supported sample in contact with an array assembly to form a structure that includes the backing element and array assembly. The structure is then held together using a subject array assay device and the array substrate and the backing element are deflected to substantially the same curvature.
摘要翻译： 提供了用于进行阵列测定的装置和方法。 本发明的阵列测定装置的实施例包括（1）底座，（2）盖子和（3）用于将盖子保持在基座上的夹紧构件，其中当盖子围绕包括 与背衬元件间隔开的阵列组件，阵列组件和背衬元件被偏转到基本上相同的曲率。 本发明方法的实施方案包括将样品与背衬元件接触并将支撑元件支撑的样品与阵列组件接触以形成包括背衬元件和阵列组件的结构。 然后使用主题阵列测定装置将结构保持在一起，并且阵列基板和背衬元件被偏转到基本上相同的曲率。
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5.发明授权公开(公告)号：US07153689B2
公开(公告)日：2006-12-26
申请号：US10211623
申请日：2002-08-01
IPC分类号： G01N35/02
CPC分类号： B08B9/0323 , B01L3/0241 , B01L99/00 , B01L2400/049 , B08B9/0327 , B08B9/08 , Y10T436/114998 , Y10T436/2575
摘要： Apparatus and methods are disclosed for cleaning and priming a droplet dispensing device having a plurality of nozzles aligned in at least one row. A dispensing surface of the dispensing device comprising the nozzles is sealingly engaged to form a chamber adjacent the dispensing surface. A wash fluid is introduced into the chamber and removed from the chamber. A priming vacuum is applied individually, and preferably, simultaneously, to at least a portion of the plurality of the nozzles. Optionally, a wash fluid is subsequently introduced into the chamber and removed from the chamber to rinse the dispensing surface.
摘要翻译： 公开了用于清洁和起泡具有在至少一排排列的多个喷嘴的液滴分配装置的装置和方法。 包括喷嘴的分配装置的分配表面被密封地接合以形成邻近分配表面的腔室。 将洗涤流体引入室中并从室中移出。 单独施加起动真空，优选同时施加到多个喷嘴的至少一部分。 任选地，洗涤流体随后被引入腔室并从腔室中移出以冲洗分配表面。
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公开(公告)号：US5197916A
公开(公告)日：1993-03-30
申请号：US902859
申请日：1992-06-23
IPC分类号： A22C25/17
CPC分类号： A22C25/17
摘要： A process and apparatus for skinning fish, particularly tuna fish, which comprises passing a precooked and cooled fish along conveyor belt means and the like while a series of rotating brushes above one side of and adjacent to the belly and back of the fish scrape the skin from those parts of the fish, passing the fish on the conveyor belt to a wheel around which the belt passes while a second belt contacts the opposite side of the fish and also passes around the wheel to hold the fish intact on the wheel until the fish is half way around the wheel and is turned over, depositing the turned over fish onto a third conveyor belt that receives the fish with the unscraped side thereof in the upper position, subjecting the unscraped side of the fish, and optionally, the belly and back thereof, to the rotating brushes to remove substantially all of the skin from the fish, and simultaneously spraying streams of water on the fish passing thereunder and the belts while removing skin from the fish and reducing deposit of the debris therefrom on the abrading apparatus.
摘要翻译： 一种用于剥皮鱼，特别是金枪鱼的方法和装置，其包括使预煮和冷却的鱼沿着输送带装置等通过，同时在鱼的腹部和背部的一侧并且靠近鱼的后面的一系列旋转刷擦拭皮肤 从鱼的那些部分，将传送带上的鱼传递到皮带通过的轮，而第二皮带接触鱼的相对侧，并且绕过轮，以将鱼完好地保持在轮上直到鱼 围绕车轮一半转过来，将转过的鱼放置在第三个输送带上，该第三个输送带将鱼的未切割的一侧接收在上部位置，使鱼的未切割的一面，以及可选的腹部和背部 旋转的刷子从鱼中去除基本上所有的皮肤，并且同时在通过其的鱼和皮带上喷洒水流，同时从皮肤上除去皮肤 并且在研磨装置上减少碎屑沉积物。
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公开(公告)号：US5653832A
公开(公告)日：1997-08-05
申请号：US435140
申请日：1995-05-05
CPC分类号： B29C65/08 , B29C65/7838 , B29C65/7841 , B29C66/12441 , B29C66/12469 , B29C66/131 , B29C66/53247 , B29C66/61 , B29C66/63 , B29C66/72328 , B29C66/7392 , B29C66/81431 , B29C66/8322 , B65B61/186 , B29L2031/7166 , B31B2201/9085 , Y10S493/929
摘要： A fitment comprising a pouring spout having a peripheral flange at one end and a closure at a second end is attached to a paperboard carton formed with a hole in a side panel. The carton is moved intermittently along a conveyor, such as that used in a filling machine. An arm having a spud oscillates about a horizontal axis parallel to the conveyor. The arm is pivoted to down position as the carton reaches the fitment attaching station so that the fitment enters the open end of the carton with the spud aligned with the carton hole. The arm is mounted on a first carriage which reciprocates horizontally in a first direction to project the closure through the hole until the flange abuts the inside of the carton panel. An ultrasonic welding horn is mounted on a second carriage which reciprocates in alignment with the first carriage in a second direction opposite the first direction. The horn welds the fitment flange to the inside of the carton panel.
摘要翻译： 包括在一端具有周边凸缘和在第二端处的封闭件的倾倒嘴的配件被附接到在侧板中形成有孔的纸板纸箱。 纸箱沿着输送机间歇地移动，例如在灌装机中使用的输送机。 具有引脚的臂围绕平行于输送机的水平轴振荡。 当纸板箱到达配件附着工位时，臂被枢转到向下的位置，使得配件进入纸板箱的开口端，并使用与纸箱孔对准的喷头。 臂安装在第一滑架上，第一滑架在第一方向上水平往复运动，以使盖通过孔突出，直到凸缘抵接在纸板面板的内部。 超声波焊接喇叭安装在第二滑架上，该第二滑架与第一滑架对齐地沿与第一方向相反的第二方向往复运动。 喇叭将配件法兰焊接到纸板面板的内部。
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