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公开(公告)号：US11304798B2
公开(公告)日：2022-04-19
申请号：US16413104
申请日：2019-05-15
Applicant: Boston Scientific Scimed, Inc.
Inventor： David Robert Wulfman , Thomas A. Wrobel , Crystal Marie Anderson-Cunanan , Joseph Thomas Delaney, Jr. , Patrick Willoughby , Mark W. Boden , Peter G. Edelman , Michael Eppihimer
Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.
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公开(公告)号：US10443107B2
公开(公告)日：2019-10-15
申请号：US16044845
申请日：2018-07-25
Applicant: Boston Scientific Scimed, Inc.
Inventor： Crystal Marie Anderson-Cunanan , Daniel J. Foster , Ray McCarthy , Mary M. Byron , David Robert Wulfman , Bradley S. Swehla
Abstract: A tissue modification apparatus includes at least a first plurality of grippers aligned in a plane adapted to secure a first edge of a patch of tissue. The plurality of grippers are each secured to a first force actuator. The first plurality of grippers are each adapted to pivot relative to the first force actuator about an axis perpendicular to the plane. In some cases, a plurality of grippers are attached to a force actuator by a passive force transfer mechanism. In some cases, individual force actuators are attached by pivoted connections to individual grippers. Methods of treating tissue can secure tensioned tissue to a frame to retain the tension during a treatment (e.g., cross-linking the tissue with a chemical cross-linker).
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公开(公告)号：US10959869B2
公开(公告)日：2021-03-30
申请号：US16007170
申请日：2018-06-13
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： David Robert Wulfman , Matthew Nelson Frost , Pieter Spitael , Thomas Martin Keating , Martyn G. Folan , Martin Hynes , Christopher Brian Rognrud , Matthew Boyer
Abstract: An example introducer is disclosed. An example introducer sheath includes a tubular member including a first layer and a second layer and a stent disposed between the first layer and the second layer of the tubular member. The stent includes an outer surface and an inner surface. Additionally, the stent is configured to shift from a first configuration to a second expanded configuration and the outer surface of the stent contacts the first layer of the tubular member in the second expanded configuration.
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公开(公告)号：US20200000476A1
公开(公告)日：2020-01-02
申请号：US16454698
申请日：2019-06-27
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： John D. Kroeger , David Robert Wulfman , Hoi Ki Ricky Chow , Adeniyi O. Aremu , Timothy A. Ostroot , Nicholas Lee Tassoni , Daniel K. Tomaschko , David Pettijohn
IPC: A61B17/12
Abstract: A vascular occlusion device for deployment within a lumen of a vessel may include a self-expanding frame configured to shift between a collapsed configuration and an expanded configuration, the self-expanding frame defining a perimeter of an interior space disposed within the self-expanding frame, and an occlusive membrane secured to the self-expanding frame. The occlusive membrane may include a suspended portion disposed within the self-expanding frame and spaced apart from the perimeter of the interior space.
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公开(公告)号：US20180353312A1
公开(公告)日：2018-12-13
申请号：US16007170
申请日：2018-06-13
Applicant: BOSTON SCIENTIFIC SCIMED, INC.
Inventor： David Robert Wulfman , Matthew Nelson Frost , Pieter Spitael , Thomas Martin Keating , Martyn G. Folan , Martin Hynes , Christopher Brian Rognrud , Matthew Boyer
CPC classification number: A61F2/966 , A61F2/86 , A61F2210/0004 , A61F2210/0014 , A61F2250/0098 , A61M25/0662 , A61M2025/0024
Abstract: An example introducer is disclosed. An example introducer sheath includes a tubular member including a first layer and a second layer and a stent disposed between the first layer and the second layer of the tubular member. The stent includes an outer surface and an inner surface. Additionally, the stent is configured to shift from a first configuration to a second expanded configuration and the outer surface of the stent contacts the first layer of the tubular member in the second expanded configuration.
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Patent Agency Ranking
公开(公告)号：US10080820B2
公开(公告)日：2018-09-25
申请号：US15250382
申请日：2016-08-29
Applicant: Boston Scientific SciMed, Inc.
Inventor： Crystal Marie Anderson-Cunanan , Daniel J. Foster , Ray McCarthy , Mary M. Byron , David Robert Wulfman , Bradley S. Swehla
CPC classification number: C14B1/00 , A61F2/2415 , A61L27/3625 , A61L27/3687 , A61L27/3691 , A61L2430/20 , A61L2430/40 , C14B1/26 , C14B17/08 , D02J1/227
Abstract: A tissue modification apparatus includes at least a first plurality of grippers aligned in a plane adapted to secure a first edge of a patch of tissue. The plurality of grippers are each secured to a first force actuator. The first plurality of grippers are each adapted to pivot relative to the first force actuator about an axis perpendicular to the plane. In some cases, a plurality of grippers are attached to a force actuator by a passive force transfer mechanism. In some cases, individual force actuators are attached by pivoted connections to individual grippers. Methods of treating tissue can secure tensioned tissue to a frame to retain the tension during a treatment (e.g., cross-linking the tissue with a chemical cross-linker).
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公开(公告)号：US20220296396A1
公开(公告)日：2022-09-22
申请号：US17700310
申请日：2022-03-21
Applicant: Boston Scientific Scimed Inc.
Inventor： David Robert Wulfman , Danielle FRANKSON , Lauren Sfakis LYDECKER , Joseph Thomas DELANEY, JR.
Abstract: A medical device that includes a body and a polymer matrix over the body. The polymer matrix includes a plurality of fibers defining a plurality of pores to permit tissue growth therethrough. The medical device includes a bio-adhesive coating at least partially covering the polymer matrix.
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公开(公告)号：US20180303972A1
公开(公告)日：2018-10-25
申请号：US15959894
申请日：2018-04-23
Applicant: Boston Scientific Scimed, Inc.
Inventor： Joseph Thomas Delaney, JR. , Patrick Willoughby , David Robert Wulfman , Andrew J. Ro , Niraj Gurung
CPC classification number: A61L27/16 , A61L27/48 , A61L2430/20 , C08J3/246 , C08J2323/22 , C08J2337/00 , C08J2479/02 , C08L53/00 , C08L2203/02 , C08L23/22
Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous, interpenetrating polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.
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公开(公告)号：US20170065744A1
公开(公告)日：2017-03-09
申请号：US15250382
申请日：2016-08-29
Applicant: Boston Scientific SciMed, Inc.
Inventor： Crystal Marie Anderson-Cunanan , Daniel J. Foster , Ray McCarthy , Mary M. Byron , David Robert Wulfman , Bradley S. Swehla
IPC: A61L27/36
CPC classification number: C14B1/00 , A61F2/2415 , A61L2430/20 , A61L2430/40 , C14B1/26 , C14B17/08 , D02J1/227
Abstract: A tissue modification apparatus includes at least a first plurality of grippers aligned in a plane adapted to secure a first edge of a patch of tissue. The plurality of grippers are each secured to a first force actuator. The first plurality of grippers are each adapted to pivot relative to the first force actuator about an axis perpendicular to the plane. In some cases, a plurality of grippers are attached to a force actuator by a passive force transfer mechanism. In some cases, individual force actuators are attached by pivoted connections to individual grippers. Methods of treating tissue can secure tensioned tissue to a frame to retain the tension during a treatment (e.g., cross-linking the tissue with a chemical cross-linker).
Abstract translation: 组织改变装置包括在适于固定组织块的第一边缘的平面中对齐的至少第一多个夹持器。 多个夹持器各自固定到第一力致动器。 第一多个夹持器各自适于相对于第一力致动器围绕垂直于该平面的轴线枢转。 在一些情况下，多个夹持器通过被动力传递机构附接到力致动器。 在某些情况下，单独的力致动器通过枢转连接附接到单独的夹持器。 处理组织的方法可以将张紧的组织固定到框架以在治疗期间保持张力（例如，用化学交联剂交联组织）。
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公开(公告)号：US20160296323A1
公开(公告)日：2016-10-13
申请号：US15082382
申请日：2016-03-28
Applicant: Boston Scientific SciMed, Inc.
Inventor： David Robert Wulfman , Thomas A. Wrobel , Crystal Marie Anderson-Cunanan , Joseph Thomas Delaney, JR. , Patrick Willoughby , Mark W. Boden , Peter G. Edelman , Michael Eppihimer
CPC classification number: A61F2/2412 , A61F2/2415 , A61L27/16 , A61L27/18 , A61L27/34 , A61L27/52 , A61L2400/12 , A61L2420/02 , A61L2420/08 , A61L2430/20 , C08L71/02
Abstract: A prosthetic heart valve leaflet includes a plurality of electrospun fibers at least partially embedded in a polymer matrix. The plurality of fibers includes a first polyisobutylene urethane copolymer having a first predetermined weight average percentage of hard segment portions and the polymer matrix includes a second polyisobutylene urethane copolymer having a second predetermined weight average percentage of the hard segment portions, wherein the first predetermined weight average percentage of the hard segment portions is greater than the second predetermined weight average percentage of the hard segment portions.
Abstract translation: 假体心脏瓣膜小叶包括至少部分地嵌入聚合物基质中的多个电纺纤维。 多根纤维包括具有第一预定重量百分比的硬链段部分的第一聚异丁烯氨基甲酸酯共聚物，聚合物基质包括具有第二预定重量百分比的硬链段部分的第二聚异丁烯聚氨酯共聚物，其中第一预定重量平均值 硬段部分的百分比大于硬段部分的第二预定重量平均百分比。
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