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    Flow method and apparatus for screening chemicals using micro x-ray fluorescence
    2.
    发明申请
    Flow method and apparatus for screening chemicals using micro x-ray fluorescence 审中-公开
    使用微X射线荧光筛选化学品的流动方法和装置

    公开(公告)号：US20050214847A1

    公开(公告)日：2005-09-29

    申请号：US11125036

    申请日：2005-05-09

    申请人： George Havrilla ,  Thomasin Miller ,  Benjamin Warner ,  Cris Lewis ,  Cynthia Mahan ,  Cyndi Wells

    发明人： George Havrilla ,  Thomasin Miller ,  Benjamin Warner ,  Cris Lewis ,  Cynthia Mahan ,  Cyndi Wells

    IPC分类号： G01N23/223 ,  C12Q1/68 ,  C12M1/34 ,  G01N33/53

    CPC分类号： G01N23/223 ,  G01N2223/076

    摘要： Flow method and apparatus for screening chemicals using micro x-ray fluorescence. The invention includes a method and apparatus for screening a mixture of potential pharmaceutical chemicals for binding to at least one target binder. According to the method, after preparing a solution of potential pharmaceutical chemicals with at least one target binder, the solution is flow-separated into at least two separated components. Each component is exposed to an x-ray excitation beam. Any component that emits a detectable x-ray fluorescence signal is isolated.

    摘要翻译： 使用微X射线荧光筛选化学品的流动方法和装置。 本发明包括用于筛选与至少一种目标粘合剂结合的潜在药物化学品混合物的方法和装置。 根据该方法，在制备具有至少一种目标粘合剂的潜在药物化学品溶液之后，将溶液流分离成至少两个分离的组分。 每个组件暴露于x射线激发光束。 发射可检测的X射线荧光信号的任何成分被分离出来。

    METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING
    3.
    发明申请
    METHOD AND APPARATUS FOR DETECTING CHEMICAL BINDING 有权
    检测化学结合的方法和装置

    公开(公告)号：US20050011818A1

    公开(公告)日：2005-01-20

    申请号：US10621825

    申请日：2003-07-16

    申请人： Benjamin Warner ,  George Havrilla ,  Thomasin Miller ,  Cyndi Wells

    发明人： Benjamin Warner ,  George Havrilla ,  Thomasin Miller ,  Cyndi Wells

    IPC分类号： G01N23/223 ,  G01N33/53 ,  B01D35/14

    CPC分类号： G01N23/223 ,  G01N33/5306 ,  G01N2223/076 ,  Y10T436/13

    摘要： The method for screening binding between a target binder and potential pharmaceutical chemicals involves sending a solution (preferably an aqueous solution) of the target binder through a conduit to a size exclusion filter, the target binder being too large to pass through the size exclusion filter, and then sending a solution of one or more potential pharmaceutical chemicals (preferably an aqueous solution) through the same conduit to the size exclusion filter after target binder has collected on the filter. The potential pharmaceutical chemicals are small enough to pass through the filter. Afterwards, x-rays are sent from an x-ray source to the size exclusion filter, and if the potential pharmaceutical chemicals form a complex with the target binder, the complex produces an x-ray fluorescence signal having an intensity that indicates that a complex has formed.

    摘要翻译： 用于筛选目标粘合剂和潜在的药物化学药物之间的结合的方法包括将目标粘合剂的溶液（优选水溶液）通过导管送到尺寸排阻过滤器，目标粘合剂太大而不能通过尺寸排阻过滤器， 然后在将目标粘合剂收集在过滤器上之后，将一种或多种潜在的药物化学品（优选水溶液）的溶液通过相同的导管送至尺寸排阻过滤器。 潜在的药物化学品足够小以通过过滤器。 之后，将x射线从x射线源发送到尺寸排阻滤光片，如果潜在的药物化学品与靶结合物形成复合物，则复合物产生具有指示复合物的强度的X射线荧光信号 已形成。

    Method and apparatus for detecting chemical binding
    4.
    发明申请
    Method and apparatus for detecting chemical binding 有权

    公开(公告)号：US20050095636A1

    公开(公告)日：2005-05-05

    申请号：US10986519

    申请日：2004-11-10

    申请人： Benjamin Warner ,  George Havrilla ,  Thomasin Miller ,  Cyndi Wells

    发明人： Benjamin Warner ,  George Havrilla ,  Thomasin Miller ,  Cyndi Wells

    IPC分类号： G01N23/223 ,  G01N33/53 ,  C12Q1/68 ,  G01N33/567

    CPC分类号： G01N23/223 ,  G01N33/5306 ,  G01N2223/076 ,  Y10T436/13

    摘要： The method for screening binding between a target binder and potential pharmaceutical chemicals involves sending a solution (preferably an aqueous solution) of the target binder through a conduit to a size exclusion filter, the target binder being too large to pass through the size exclusion filter, and then sending a solution of one or more potential pharmaceutical chemicals (preferably an aqueous solution) through the same conduit to the size exclusion filter after target binder has collected on the filter. The potential pharmaceutical chemicals are small enough to pass through the filter. Afterwards, x-rays are sent from an x-ray source to the size exclusion filter, and if the potential pharmaceutical chemicals form a complex with the target binder, the complex produces an x-ray fluorescence signal having an intensity that indicates that a complex has formed.

    Durable electrooptic devices comprising ionic liquids
    6.
    发明申请
    Durable electrooptic devices comprising ionic liquids 失效
    包含离子液体的耐用电光装置

    公开(公告)号：US20050162728A1

    公开(公告)日：2005-07-28

    申请号：US11041069

    申请日：2005-01-20

    申请人： Benjamin Warner ,  T. McCleskey ,  Anthony Burrell

    发明人： Benjamin Warner ,  T. McCleskey ,  Anthony Burrell

    IPC分类号： C25B1/00 ,  G02B5/23 ,  G02F20060101 ,  G02F1/00 ,  G02F1/15 ,  G02F1/153 ,  G02F1/155

    CPC分类号： C09K9/02 ,  B60R1/088 ,  C09K2211/1029 ,  G02F1/1521 ,  G02F1/157 ,  G02F2202/36

    摘要： Electrolyte solutions for electrochromic devices such as rear view mirrors and displays with low leakage currents are prepared using inexpensive, low conductivity conductors. Preferred electrolytes include bifunctional redox dyes and molten salt solvents with enhanced stability toward ultraviolet radiation. The solvents include lithium or quaternary ammonium cations, and perfluorinated sulfonylimide anions selected from trifluoromethylsulfonate (CF3SO3−), bis(trifluoromethylsulfonyl)imide ((CF3SO2)2N−), bis(perfluoroethylsulfonyl)imide ((CF3CF2SO2)2N−) and tris(trifluoromethylsulfonyl)methide ((CF3SO2)3C−). Electroluminescent, electrochromic and photoelectrochromic devices with nanostructured electrodes include ionic liquids with bifunctional redox dyes.

    摘要翻译： 使用廉价，低导电性的导体制备电致变色器件如后视镜和低漏电流的显示器的电解液。 优选的电解质包括双功能氧化还原染料和熔融盐溶剂，对紫外线辐射具有增强的稳定性。 溶剂包括锂或季铵阳离子，和全氟磺酰亚胺阴离子，选自三氟甲基磺酸酯（CF 3 SO 3 SO 2），双（三氟甲基磺酰基）酰亚胺 （（CF 3 SO 2）2 N - ），双（全氟乙基磺酰基）酰亚胺（（CF 3（三氟甲基磺酰基）甲基化（（3,3-二甲基-2- （CF 3 SO 2）3） - （CH 3）3）。 具有纳米结构电极的电致发光，电致变色和光电致变色装置包括具有双功能氧化还原染料的离子液体。

    Sensor comprising supported aprotic ionic liquid
    7.
    发明申请
    Sensor comprising supported aprotic ionic liquid 审中-公开
    传感器包含负载的非质子离子液体

    公开(公告)号：US20060278536A1

    公开(公告)日：2006-12-14

    申请号：US11151150

    申请日：2005-06-10

    申请人： Anthony Burrell ,  Simon Hall ,  Benjamin Warner ,  Wayne Smith ,  Jerzy Chlistunoff

    发明人： Anthony Burrell ,  Simon Hall ,  Benjamin Warner ,  Wayne Smith ,  Jerzy Chlistunoff

    IPC分类号： G01N27/26

    CPC分类号： G01N27/26

    摘要： A sensor for detecting and measuring analyte includes a working electrode, a counter electrode, and a porous support positioned in between and in contact with the working electrode and the counter electrode. At least one of the working electrode and the counter electrode is perforated. Aprotic ionic liquid fills the pores and is adsorbed on the surface of the porous support. The sensor also includes an electrical power source that provides a controlled voltage difference between the working electrode and the counter electrode, and an ammeter that measures the current flowing from the working electrode to the counter electrode.

    摘要翻译： 用于检测和测量分析物的传感器包括工作电极，对电极和位于工作电极和对电极之间并与工作电极和对电极接触的多孔支撑体。 工作电极和对电极中的至少一个是穿孔的。 非质子离子液体填充孔并吸附在多孔载体的表面上。 传感器还包括在工作电极和对电极之间提供受控电压差的电源，以及测量从工作电极流向对电极的电流的电流表。

    Reversible electro-optic device employing aprotic molten salts and method
    10.
    发明申请
    Reversible electro-optic device employing aprotic molten salts and method 审中-公开
    使用非质子熔融盐的可逆电光装置及方法

    公开(公告)号：US20060012293A1

    公开(公告)日：2006-01-19

    申请号：US11223374

    申请日：2005-09-08

    申请人： Benjamin Warner ,  T. McCleskey ,  Anthony Burrell ,  Simon Hall

    发明人： Benjamin Warner ,  T. McCleskey ,  Anthony Burrell ,  Simon Hall

    IPC分类号： C07C277/02

    CPC分类号： C07D295/023 ,  G02F1/1506

    摘要： A reversible electro-optic device includes a medium of variable transmittance to light. The medium includes a soluble redox couple of a first soluble metal containing species and a second soluble metal containing species. The metal of the soluble redox couple is capable of being electrodeposited. The medium also includes one or more anodic compound(s) capable of being oxidized. An alternate medium includes a soluble metal-containing species and a soluble anodic compound, where the soluble metal-containing species includes metal capable of being electrodeposited, and the anodic compound is capable of being oxidized to a soluble oxidized anodic compound. Another electro-optic device includes a medium of variable reflection to light.

    摘要翻译： 可逆电光装置包括对光透射率可变的介质。 介质包括含有第一可溶性金属的物质和第二可溶性金属物质的可溶性氧化还原对。 可溶性氧化还原对的金属能够电沉积。 介质还包括一种或多种能够被氧化的阳极化合物。 替代介质包括可溶性金属物质和可溶性阳极化合物，其中可溶性含金属物质包括能够电沉积的金属，并且阳极化合物能够被氧化成可溶性氧化阳极化合物。 另一种电光装置包括可变光反射介质。