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公开(公告)号:US20240272183A1
公开(公告)日:2024-08-15
申请号:US18369846
申请日:2023-09-19
Applicant: Berkeley Lights, Inc.
Inventor: Darshan Thaker , Matthew E. Fowler , Samira A. Nedungadi , Daniel Banda Villanueva , Brandon R. Bruhn , Nenad Bozinovic , Kellen C. Mobilia
CPC classification number: G01N35/00623 , G01N35/00693 , G01N35/00871 , G06N20/00 , G01N2035/009 , G01N2035/0091
Abstract: A system and a method for dynamically optimizing an instrument system workflow based on operational monitoring and managing of a workflow for a hardware system. The system includes instrument resources and sample chambers, each resource and chamber with a dedicated sensor configured to acquire data. The system further includes a computing device communicatively connected to the instrument resources and sample chambers. The computing device includes a software application or program comprising a workflow builder, an execution engine, an analytics engine, a virtual system modeling engine, and an optional machine learning engine.
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2.
公开(公告)号:US10829728B2
公开(公告)日:2020-11-10
申请号:US16010176
申请日:2018-06-15
Applicant: Berkeley Lights, Inc.
Inventor: Volker L. S. Kurz , Troy A. Lionberger , Eric K. Sackmann , Kai W. Szeto , Paul M. Lebel , Brandon R. Bruhn , Keith J. Breinlinger , Eric D. Hobbs , Andrew W. McFarland , J. Tanner Nevill , Xiaohua Wang
Abstract: Apparatuses and methods are described for the use of optically driven bubble, convective and displacing fluidic flow to provide motive force in microfluidic devices. Alternative motive modalities are useful to selectively dislodge and displace micro-objects, including biological cells, from a variety of locations within the enclosure of a microfluidic device.
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公开(公告)号:US20170354969A1
公开(公告)日:2017-12-14
申请号:US15487795
申请日:2017-04-14
Applicant: Berkeley Lights,Inc.
Inventor: Troy A. Lionberger , Brandon R. Bruhn , John A. Tenney , Eric D. Hobbs
IPC: B01L3/00 , G01N27/447 , B03C5/00
CPC classification number: B01L3/50273 , B01L3/502715 , B01L3/502761 , B01L2200/0647 , B01L2400/0424 , B01L2400/0454 , B03C5/005 , B03C5/024 , B03C5/026 , B03C2201/26 , G01N27/44791
Abstract: Optically-actuated microfluidic devices permit the use of spatially-modulated light to manipulate micro-objects such as biological cells. Systems and methods are described for providing sequences of light patterns to move and direct a plurality of micro-objects within the environment of a microfluidic device. The sequenced light patterns provide improved efficiency in directing the transport of the plurality of micro-objects. Other embodiments are described.
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公开(公告)号:US11802883B2
公开(公告)日:2023-10-31
申请号:US16882331
申请日:2020-05-22
Applicant: Berkeley Lights, Inc.
Inventor: Darshan Thaker , Matthew E. Fowler , Samira A. Nedungadi , Daniel A. Banda Villanueva , Brandon R. Bruhn , Nenad Bozinovic , Kellen C. Mobilia
CPC classification number: G01N35/00623 , G01N35/00693 , G01N35/00871 , G06N20/00 , G01N2035/009 , G01N2035/0091
Abstract: A system and a method for dynamically optimizing an instrument system workflow based on operational monitoring and managing of a workflow for a hardware system. The system includes instrument resources and sample chambers, each resource and chamber with a dedicated sensor configured to acquire data. The system further includes a computing device communicatively connected to the instrument resources and sample chambers. The computing device includes a software application or program comprising a workflow builder, an execution engine, an analytics engine, a virtual system modeling engine, and an optional machine learning engine.
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公开(公告)号:US20210213444A1
公开(公告)日:2021-07-15
申请号:US16893885
申请日:2020-06-05
Applicant: Berkeley Lights, Inc.
Inventor: Troy A. Lionberger , Brandon R. Bruhn , John A. Tenney , Eric D. Hobbs
IPC: B01L3/00 , G01N27/447 , B03C5/00 , B03C5/02
Abstract: Optically-actuated microfluidic devices permit the use of spatially-modulated light to manipulate micro-objects such as biological cells. Systems and methods are described for providing sequences of light patterns to move and direct a plurality of micro-objects within the environment of a microfluidic device. The sequenced light patterns provide improved efficiency in directing the transport of the plurality of micro-objects. Other embodiments are described.
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公开(公告)号:US11376591B2
公开(公告)日:2022-07-05
申请号:US16893885
申请日:2020-06-05
Applicant: Berkeley Lights, Inc.
Inventor: Troy A. Lionberger , Brandon R. Bruhn , John A. Tenney , Eric D. Hobbs
IPC: B01L3/00 , G01N27/447 , B03C5/00 , B03C5/02
Abstract: Optically-actuated microfluidic devices permit the use of spatially-modulated light to manipulate micro-objects such as biological cells. Systems and methods are described for providing sequences of light patterns to move and direct a plurality of micro-objects within the environment of a microfluidic device. The sequenced light patterns provide improved efficiency in directing the transport of the plurality of micro-objects. Other embodiments are described.
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公开(公告)号:US20200371126A1
公开(公告)日:2020-11-26
申请号:US16882331
申请日:2020-05-22
Applicant: Berkeley Lights, Inc.
Inventor: Darshan Thaker , Matthew E. Fowler , Samira A. Nedungadi , Daniel Banda, JR. , Brandon R. Bruhn , Nenad Bozinovic , Kellen C. Mobilia
Abstract: A system and a method for dynamically optimizing an instrument system workflow based on operational monitoring and managing of a workflow for a hardware system. The system includes instrument resources and sample chambers, each resource and chamber with a dedicated sensor configured to acquire data. The system further includes a computing device communicatively connected to the instrument resources and sample chambers. The computing device includes a software application or program comprising a workflow builder, an execution engine, an analytics engine, a virtual system modeling engine, and an optional machine learning engine.
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公开(公告)号:US10675625B2
公开(公告)日:2020-06-09
申请号:US15487795
申请日:2017-04-14
Applicant: Berkeley Lights, Inc.
Inventor: Troy A. Lionberger , Brandon R. Bruhn , John A. Tenney , Eric D. Hobbs
IPC: B01L3/00 , G01N27/447 , B03C5/00 , B03C5/02
Abstract: Optically-actuated microfluidic devices permit the use of spatially-modulated light to manipulate micro-objects such as biological cells. Systems and methods are described for providing sequences of light patterns to move and direct a plurality of micro-objects within the environment of a microfluidic device. The sequenced light patterns provide improved efficiency in directing the transport of the plurality of micro-objects. Other embodiments are described.
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9.
公开(公告)号:US11802264B2
公开(公告)日:2023-10-31
申请号:US17067971
申请日:2020-10-12
Applicant: Berkeley Lights, Inc.
Inventor: Volker L. S. Kurz , Troy A. Lionberger , Eric K. Sackmann , Kai W. Szeto , Paul M. Lebel , Brandon R. Bruhn , Keith J. Breinlinger , Eric D. Hobbs , Andrew W. McFarland , J. Tanner Nevill , Xiaohua Wang
CPC classification number: C12M23/16 , B01L3/502761 , C12M23/20 , C12M33/12 , B01L2200/0668 , B01L2300/1822 , B01L2400/0415 , B01L2400/0427 , B01L2400/0442 , B01L2400/0454 , B01L2400/086
Abstract: Apparatuses and methods are described for the use of optically driven bubble, convective and displacing fluidic flow to provide motive force in microfluidic devices. Alternative motive modalities are useful to selectively dislodge and displace micro-objects, including biological cells, from a variety of locations within the enclosure of a microfluidic device.
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10.
公开(公告)号:US20210102150A1
公开(公告)日:2021-04-08
申请号:US17067971
申请日:2020-10-12
Applicant: Berkeley Lights, Inc.
Inventor: Volker L.S. Kurz , Troy A. Lionberger , Eric K. Sackmann , Kai W. Szeto , Paul M. Lebel , Brandon R. Bruhn , Keith J. Breinlinger , Eric D. Hobbs , Andrew W. McFarland , J. Tanner Nevill , Xiaohua Wang
Abstract: Apparatuses and methods are described for the use of optically driven bubble, convective and displacing fluidic flow to provide motive force in microfluidic devices. Alternative motive modalities are useful to selectively dislodge and displace micro-objects, including biological cells, from a variety of locations within the enclosure of a microfluidic device.
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