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公开(公告)号:US20050090797A1
公开(公告)日:2005-04-28
申请号:US10626282
申请日:2003-07-24
申请人: Joseph Almasian , Brett Belongia , Frank Lentine , Martin Morrissey , Curtis Nauseda , Chau Nguyen , Stephen Proulx , Naren Renganath
发明人: Joseph Almasian , Brett Belongia , Frank Lentine , Martin Morrissey , Curtis Nauseda , Chau Nguyen , Stephen Proulx , Naren Renganath
CPC分类号: F16L29/007 , A61M39/14 , A61M39/18 , A61M39/22 , F16L2201/44 , G01N1/2035 , G01N2001/205 , G01N2001/2071 , Y10S604/905 , Y10T137/87925
摘要: A sterile to sterile connection device comprising a connector and one or more coupling devices. The connector has body portion which has two openings sealed from the environment so as to form a sterile environment within the connector. At least one of the openings being sealed from the environment by a sterile barrier plug. The connector also has a port capable movement within the body of the connector to at least an open and a closed position. The coupling device is formed of a body having two openings and a stem having a bore through at least a portion of the stem. The stem is contained within the body and capable of moving at least linearly through the body between a first and second stem position. One of the openings of the stem is sealed from the environment by a sterile barrier plug and the other is sealed to a presterilized component. The coupling device opening containing the sterile barrier plug is attached to either the inlet or outlet of the connector.
摘要翻译: 一种无菌至无菌连接装置,包括连接器和一个或多个联接装置。 连接器具有主体部分,其具有与环境密封的两个开口,以便在连接器内形成无菌环境。 至少一个开口通过无菌隔离塞与环境密封。 连接器还具有能够在连接器主体内移动至少至少一个打开和关闭位置的端口。 联接装置由具有两个开口的主体和具有穿过杆的至少一部分的孔的杆构成。 杆体容纳在主体内并且能够至少在第一和第二杆位置之间线性移动通过主体。 杆的一个开口通过无菌阻塞塞与环境密封,另一个被密封到预先灭活的部件上。 包含无菌阻塞塞的联接装置开口连接到连接器的入口或出口。
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公开(公告)号:US20080131960A1
公开(公告)日:2008-06-05
申请号:US11978913
申请日:2007-10-30
申请人: Brett Belongia , Neil Schauer , Stephen Proulx
发明人: Brett Belongia , Neil Schauer , Stephen Proulx
IPC分类号: C12M1/00
摘要: A bioreactor formed of a flexible material is provided having a constant aspect ratio and an adjustable length. The bioreactor is rendered self standing by a support means secured to the bioreactor.
摘要翻译: 提供由柔性材料形成的生物反应器,其具有恒定的纵横比和可调整的长度。 生物反应器通过固定在生物反应器上的支撑装置使其自我站立。
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公开(公告)号:US20050029301A1
公开(公告)日:2005-02-10
申请号:US10635124
申请日:2003-08-06
申请人: Brett Belongia , Stephen Proulx
发明人: Brett Belongia , Stephen Proulx
CPC分类号: G01F11/284 , B01L3/0293 , G01N35/1002 , G01N35/1016 , Y10T137/86324
摘要: A single-use fluid dispenser cartridge, installable or installed into a host fluid dispensing apparatus, is described. The single-use fluid dispenser cartridge is provided with a fluid reservoir, a fill tube assembly, and means for controlling pressure within the cartridge by gating gas into or out of the reservoir and/or the fill tube assembly. The gas gating mean enables, in certain embodiments, use of a fluid reservoir that is “substantially rigid”.
摘要翻译: 描述可安装或安装在主体流体分配装置中的一次性流体分配器盒。 一次性流体分配器盒设置有流体储存器,填充管组件和用于通过将气体进入或流出储存器和/或填充管组件来控制筒内的压力的装置。 在某些实施例中,气体门控装置能够使用“基本刚性”的流体储存器。
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公开(公告)号:US20110197989A1
公开(公告)日:2011-08-18
申请号:US13092566
申请日:2011-04-22
IPC分类号: B65B3/04
CPC分类号: F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , A61M2039/1027 , A61M2039/222 , F16K3/265 , F16K13/04 , F16K15/18 , F16L37/107
摘要: The present invention relates to a process for the sterile transfer of fluids, be they liquids or gases. It uses a presterilized device comprised of a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to a downstream component such as a filter, pipeline, sample bag and the like. The plunger has corresponding first and second ends. The first end of the plunger when it the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components. The device is attached to an upstream component and the face and the first end of the plunger are steam sterilized in place.
摘要翻译: 本发明涉及一种无菌转移流体(无论是液体还是气体)的方法。 它使用由具有通过其内部的至少一部分形成的孔的主体构成的预灭菌装置。 孔内包含一个可移动的柱塞。 身体有第一和第二端。 第一端包含设计成连接到上游部件的面。 第二端连接到诸如过滤器,管道,样品袋等的下游部件。 柱塞具有相应的第一和第二端。 柱塞在其关闭位置时的第一端与主体的表面对齐,该表面组合形成一个可蒸汽表面,并且一个无菌隔离物抵抗环境的内部其余部分,柱塞和下游部件。 该装置连接到上游部件,柱塞的表面和第一端被蒸汽灭菌就位。
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公开(公告)号:US20070215891A1
公开(公告)日:2007-09-20
申请号:US11418622
申请日:2006-05-04
申请人: Russell Dahl , Joseph Partlow , Stephen Proulx
发明人: Russell Dahl , Joseph Partlow , Stephen Proulx
IPC分类号: H01L33/00
CPC分类号: H01L25/0753 , H01L33/60 , H01L2924/0002 , H01L2924/00
摘要: A light emitting diode (LED) array with beam directors outputting a high-intensity collimated beam. The LED array is constructed from a substrate component on which the LEDs and necessary electronics are disposed and a director attachment having a plurality of beam directors. The beam directors have a unique structure that is designed to shape the light beam into a collimated form. The LEDs are arranged in a pattern on the substrate, and the beam directors are arranged within the director attachment to coincide with the LEDs. The substrate and the director attachment may be manufactured and processed as separate components; they are then affixed together for operation.
摘要翻译: 一种发光二极管(LED)阵列,其具有输出高强度准直光束的光束指向器。 LED阵列由其上布置有LED和必要的电子设备的基板部件和具有多个光束引导件的引导器附件构成。 光束导向器具有独特的结构,其被设计成将光束成形为准直的形式。 LED以衬底上的图案布置,并且光束指向器布置在引导器附件内以与LED重合。 基板和引导件附件可以作为单独的部件被制造和处理; 然后将它们固定在一起进行操作。
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公开(公告)号:US06902671B2
公开(公告)日:2005-06-07
申请号:US10011676
申请日:2001-12-03
IPC分类号: B01D63/14 , A61L2/00 , A61L2/02 , A61L2/28 , B01D19/00 , B01D61/18 , B01D61/20 , B01D63/06 , B01D63/08 , B01D65/02 , B01D65/10 , B01D67/00 , B01D69/00 , B01D69/12 , B01D63/00
CPC分类号: B01D67/0088 , A61L2/0017 , A61L2/02 , A61L2/022 , A61L2/28 , B01D19/0031 , B01D61/18 , B01D61/20 , B01D63/067 , B01D63/082 , B01D63/14 , B01D65/022 , B01D65/102 , B01D69/00 , B01D69/02 , B01D69/12 , B01D2201/0407 , B01D2325/08 , B01D2325/36 , B01D2325/38
摘要: A barrier filter useful for aseptically discharging both gaseous and liquid fluids from a chemical process system is disclosed The barrier filter comprises, within a common enclosure, one or several filter membranes having singularly or collectively a mixture or hydrophobic and hydrophilic regions. The common enclosure of the barrier filter is provided with a fluid inlet and a fluid outlet. All filter membranes are located within the fluid path between the fluid inlet and the fluid outlet. A variety of membrane-based systems, into which such barrier filter is installed, are also disclosed.
摘要翻译: 公开了一种用于从化学处理系统无菌排放气体和液体流体的屏障过滤器。阻挡过滤器在公共外壳内包含一个或多个单独或统称为混合物或疏水和亲水区域的过滤膜。 屏障过滤器的共同外壳设有流体入口和流体出口。 所有过滤膜位于流体入口和流体出口之间的流体路径内。 还公开了安装这种屏障过滤器的各种膜系统。
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公开(公告)号:US5980759A
公开(公告)日:1999-11-09
申请号:US476149
申请日:1995-06-07
CPC分类号: B01D29/21 , B01D2201/182
摘要: A filter cartridge is provided which includes (a) a wound depth filter or a cylindrical seamless depth filter and (b) a pleated filter having a lower micron retention rating than the depth filter. The depth filter and pleated filter surround a central opening. The cartridge is sealed and an appropriate inlet or outlet is provided in order to assure sequential fluid flow first through the depth filter and then through the pleated filter.
摘要翻译: 提供了一种滤筒,其包括(a)卷绕深度过滤器或圆柱形无缝深度过滤器,和(b)具有比深度过滤器更低的微米保持等级的打褶过滤器。 深度过滤器和褶皱过滤器围绕中心开口。 墨盒被密封,并且提供适当的入口或出口,以便确保顺序流体首先流过深度过滤器,然后通过打褶过滤器。
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8.
公开(公告)号:US5798049A
公开(公告)日:1998-08-25
申请号:US767105
申请日:1996-12-04
申请人: Stephen Proulx , Paul J. Cook , Michael L. Heise
发明人: Stephen Proulx , Paul J. Cook , Michael L. Heise
CPC分类号: B01D25/24 , B01D25/001 , B01D29/21 , B01D2201/0407 , B01D2201/182 , B01D2201/188
摘要: A filter element for filtering a particle-containing paint composition or a particle loading slurry composition which is a precursor to a particle-containing paint composition is provided. The filtration element comprises at least one filtration layer formed from woven polymer fibers and having substantially uniform pores and two spacer layers. The spacer layers have raised projections to create a space between adjacent spacer layers having contacting projections. The filtration element has a pleated or spirally wound configuration.
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公开(公告)号:US5477155A
公开(公告)日:1995-12-19
申请号:US105525
申请日:1993-08-11
CPC分类号: B01D65/102 , G01N15/088
摘要: A new method and apparatus is described for conducting an integrity test on porous membranes and membrane filters and for conducting a pore-size characterization of membrane. The method and apparatus apply to membrane integrity tests and pore-size characterizations which are based on the dependence on the pore size of the pressure required to intrude a non-wetting, electrically conductive liquid into and through the pores. Electrical-measurement methods are described for identifying the pressure at which intrusion occurs.
摘要翻译: 描述了一种用于对多孔膜和膜过滤器进行完整性测试并用于进行膜的孔径尺寸表征的新方法和装置。 该方法和装置适用于膜完整性测试和孔径特征,其基于将非湿润导电液体侵入和穿过孔所需的压力孔径的依赖性。 描述电测量方法用于识别侵入发生的压力。
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公开(公告)号:US08562572B2
公开(公告)日:2013-10-22
申请号:US11350384
申请日:2006-02-08
IPC分类号: A61M5/00
CPC分类号: F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , A61M2039/1027 , A61M2039/222 , F16K3/265 , F16K13/04 , F16K15/18 , F16L37/107
摘要: The present invention relates to a sterile sample collection device for fluids and a method of using the same. It is comprised of a transfer device having a body with a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to tube which is then connected to a collection bag. The plunger has corresponding first and second ends. The first end of the plunger when in the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components.
摘要翻译: 本发明涉及一种用于流体的无菌样品收集装置及其使用方法。 它由具有通过其内部的至少一部分形成的孔的本体的转移装置组成。 孔内包含一个可移动的柱塞。 身体有第一和第二端。 第一端包含设计成连接到上游部件的面。 第二端连接到管,然后连接到收集袋。 柱塞具有相应的第一和第二端。 当处于关闭位置时,柱塞的第一端与主体的表面对准,该表面组合形成可蒸发的表面,并且将抗环境的无菌屏障组合到主体内部的其余部分,柱塞和下游部件。
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