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    Coated implantable medical device
    1.
    发明申请
    Coated implantable medical device 有权
    涂层可植入医疗器械

    公开(公告)号：US20070050010A1

    公开(公告)日：2007-03-01

    申请号：US11515395

    申请日：2006-09-01

    申请人： Brian Bates ,  Anthony Ragheb ,  Neal Fearnot ,  William Voorhees ,  Thomas Kozma ,  David Grewe ,  Darin Schaeffer

    发明人： Brian Bates ,  Anthony Ragheb ,  Neal Fearnot ,  William Voorhees ,  Thomas Kozma ,  David Grewe ,  Darin Schaeffer

    IPC分类号： A61F2/86 ,  A61F2/06

    CPC分类号： A61F2/91 ,  A61F2/24 ,  A61F2/82 ,  A61F2/885 ,  A61F2250/0068 ,  A61K51/1282 ,  A61L27/306 ,  A61L27/54 ,  A61L29/085 ,  A61L29/106 ,  A61L29/16 ,  A61L31/088 ,  A61L31/10 ,  A61L31/16 ,  A61L33/022 ,  A61L2300/256 ,  A61L2300/416 ,  A61L2300/602 ,  A61L2300/606 ,  A61L2300/608 ,  A61N5/1002 ,  C08L65/04

    摘要： A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; and at least one layer 18 of a bioactive material posited on at least a portion of the coating layer 16, wherein the coating layer 16 provides for the controlled release of the bioactive material from the coating layer. In addition, at least one porous layer 20 can be posited over the bioactive material layer 18, wherein the porous layer includes a polymer and provides for the controlled release of the bioactive material therethrough. Preferably, the structure 12 is a coronary stent. The porous layer 20 includes a polymer applied preferably by vapor or plasma deposition and provides for a controlled release of the bioactive material. It is particularly preferred that the polymer is a polyamide, parylene or a parylene derivative, which is deposited without solvents, heat or catalysts, and merely by condensation of a monomer vapor.

    摘要翻译： 涂覆的可植入医疗装置10包括适于引入到血管系统，食道，气管，结肠，胆道或尿道中的结构12; 至少一个涂层16位于该结构的一个表面上; 和至少一层生物活性物质的层18位于涂层16的至少一部分上，其中涂层16提供生物活性材料从涂层的受控释放。 此外，至少一个多孔层20可以放置在生物活性材料层18上方，其中多孔层包括聚合物并提供生物活性材料通过其控制释放。 优选地，结构12是冠状动脉支架。 多孔层20包括优选通过蒸气或等离子体沉积施加的聚合物，并提供生物活性材料的受控释放。 特别优选的是，聚合物是聚酰胺，聚对二甲苯或聚对二甲苯衍生物，它们不经溶剂，热或催化剂沉积，并且仅通过单体蒸气的冷凝而沉积。

    Eluting, implantable medical device
    4.
    发明申请
    Eluting, implantable medical device 审中-公开
    洗脱，植入式医疗器械

    公开(公告)号：US20070073385A1

    公开(公告)日：2007-03-29

    申请号：US11523797

    申请日：2006-09-18

    申请人： Darin Schaeffer ,  David Grewe ,  Patrick Ruane

    发明人： Darin Schaeffer ,  David Grewe ,  Patrick Ruane

    IPC分类号： A61F2/90

    CPC分类号： A61L31/082 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/30322 ,  A61F2002/91508 ,  A61F2002/91516 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2230/0054 ,  A61F2250/0023 ,  A61F2250/0026 ,  A61F2250/0068 ,  A61L31/146 ,  A61L31/16 ,  A61L2300/416

    摘要： An intraluminal device is provided with a porous structure. The porous structure may be loaded with a bioactive substance to treat surrounding tissues after the intraluminal device has been implanted. The porous structure may be made by depositing a metal film on a foam structure using chemical vapor deposition. Porous structures may also be made by sintering or applying a ceramic layer to the intraluminal device. An intraluminal device is also provided with a ceramic material applied to generally straight portions of the device structure but not to portions adapted to bend. One advantage is that the ceramic material is less likely to fracture since it is applied to regions that experience less strain.

    摘要翻译： 管腔内装置具有多孔结构。 在植入腔内装置之后，多孔结构可装载生物活性物质以治疗周围组织。 多孔结构可以通过使用化学气相沉积在金属泡沫结构上沉积金属膜来制造。 也可以通过烧结或将陶瓷层施加到腔内装置来制造多孔结构。 管腔内装置还设置有施加到装置结构的大致直线部分的陶瓷材料，但是不适于弯曲的部分。 一个优点是陶瓷材料不太可能破裂，因为它被应用于经历较小应变的区域。

    Sling-based treatment of obstructive sleep apnea
    5.
    发明授权
    Sling-based treatment of obstructive sleep apnea 有权

    公开(公告)号：US10022263B2

    公开(公告)日：2018-07-17

    申请号：US13550065

    申请日：2012-07-16

    申请人： Arun Mohan ,  Darin Schaeffer ,  Patrick C. Melder

    发明人： Arun Mohan ,  Darin Schaeffer ,  Patrick C. Melder

    IPC分类号： A61F5/56

    摘要： Slings, kits, and methods useful in the treatment of Obstructive Sleep Apnea (OSA) are described. An exemplary sling comprises a main body extending along a lengthwise axis and having first and second opposing ends, first and second opposing sides, and first and second opposing surfaces. Each end defines an end loop that defines a passageway extending through the main body. An exemplary method of treatment comprises creating two openings in the mandible of a patient; creating two longitudinal tunnels in the tongue of the patient; creating a transverse tunnel in the tongue of the patient; advancing a sling through the transverse tunnel; pulling each end of the sling through one of the longitudinal tunnels and through one of the openings in the mandible; pulling the tongue toward the front of the mouth or mandible; and securing the sling to a tissue to support the tongue in a new position.

    Methods of Providing Access to a Salivary Duct
    9.
    发明申请
    Methods of Providing Access to a Salivary Duct 有权
    提供唾液管道的方法

    公开(公告)号：US20130245662A1

    公开(公告)日：2013-09-19

    申请号：US13607861

    申请日：2012-09-10

    申请人： Darin Schaeffer ,  Thomas Cherry ,  Kathryn Evert ,  Jack Kolenda

    发明人： Darin Schaeffer ,  Thomas Cherry ,  Kathryn Evert ,  Jack Kolenda

    IPC分类号： A61M29/02

    CPC分类号： A61M29/02 ,  A61M2025/0681

    摘要： Methods of treatment are described. More particularly, methods of providing access to a bodily passage, such as a salivary duct, are described herein. For example, methods of providing access to a salivary duct and introducing a sheath and wire guide are described herein. In addition, various methods of treatment are described herein. For example, methods of treating a stone located within a salivary duct are described herein.

    摘要翻译： 描述了治疗方法。 更具体地，本文描述了提供对身体通道（例如唾液管）的通路的方法。 例如，本文描述了提供对唾液管的通路和引入鞘和线引导件的方法。 此外，本文描述了各种治疗方法。 例如，本文描述了治疗位于唾液管内的石块的方法。