公开(公告)号：US20140066595A1

公开(公告)日：2014-03-06

申请号：US14010246

申请日：2013-08-26

Applicant: Emily Anderson ,  Peter Bell ,  Penny Jensen ,  Jon Karpilow ,  Anja Smith ,  Krishna Vattem ,  Brian Webb ,  Devin Leake ,  Alex Medford ,  Elena Maksimova ,  Craig Smith

Inventor： Emily Anderson ,  Peter Bell ,  Penny Jensen ,  Jon Karpilow ,  Anja Smith ,  Krishna Vattem ,  Brian Webb ,  Devin Leake ,  Alex Medford ,  Elena Maksimova ,  Craig Smith

IPC: C12P21/00 ,  C07K14/00

CPC classification number: C12P21/00 ,  C07K14/00

Abstract: Cell-free extracts, methods for producing these extracts, methods for using these extracts, compositions that facilitate production of these extracts and kits that contain these extracts are provided. By increasing or decreasing certain gene products through, for example, the use of siRNA or mimics, one can develop mammalian cell-free extracts that have desired levels of efficiency.

Abstract translation: 提供了无细胞提取物，用于生产这些提取物的方法，使用这些提取物的方法，促进这些提取物生产的组合物和含有这些提取物的试剂盒。 通过例如使用siRNA或模拟物来增加或减少某些基因产物，可以开发具有期望的效率水平的哺乳动物无细胞提取物。

公开(公告)号：US20080103059A1

公开(公告)日：2008-05-01

申请号：US12001850

申请日：2007-12-13

Applicant: Brian Webb ,  Jinlin Peng ,  Michael Brady ,  Mircea Despa ,  Keith Horn ,  Joydeep Lahiri ,  David Root ,  James Stamatoff

Inventor： Brian Webb ,  Jinlin Peng ,  Michael Brady ,  Mircea Despa ,  Keith Horn ,  Joydeep Lahiri ,  David Root ,  James Stamatoff

IPC: C40B30/04

CPC classification number: B01L3/50853 ,  B01J2219/00317 ,  B01J2219/00504 ,  B01J2219/00511 ,  B01J2219/00585 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00619 ,  B01J2219/00621 ,  B01J2219/00626 ,  B01J2219/00637 ,  B01J2219/00653 ,  B01J2219/00662 ,  B01J2219/00707 ,  B01L3/5025 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2300/046 ,  B01L2300/0636 ,  B01L2300/0829 ,  C12Q1/6837 ,  C40B60/14 ,  G01N33/54366 ,  G01N33/54373 ,  G01N33/54386 ,  G01N35/028

Abstract: A device and methods for performing biological or chemical analysis is provided. The device includes an array of three-dimensional microcolumns projecting away from a support plate. Each microcolumn has a relatively planar, first surface remote from the support plate. An array of multiple, different biological materials may be attached to the first surface. The device, when used in combination with existent micro-titer well plates, can improve efficiency of binding assays using microarrays for high-throughput capacity.

公开(公告)号：US08974147B1

公开(公告)日：2015-03-10

申请号：US14508446

申请日：2014-10-07

Applicant: Brian Webb

Inventor： Brian Webb

IPC: F16L1/06 ,  F16L3/04

CPC classification number: F16L1/24 ,  F16L1/06

Abstract: A device for controlling buoyancy of a buried pipeline, the device comprising a form placed atop the pipeline and a flexible strap extending around the form adjacent its top. The form may comprise a first trough located adjacent the first side of the pipeline, a second trough located adjacent the opposing second side of the pipeline, and a middle section with an inverted-U-shaped cross section such that the middle portion fits over the top of the pipeline and joins the first trough and the second trough. The troughs are filled with backfill when the pipeline is buried. Thus, when fully installed, the device may comprise the slot form, the strap, and the backfill. As the pipeline tends to rise, the straps deform, bringing the sides of the troughs inward and compressing the backfill therein. This prevents further upward movement of the pipeline.

Abstract translation: 一种用于控制埋设管道浮力的装置，该装置包括放置在管道顶部的形式和围绕邻近其顶部的形式延伸的柔性带。 该形式可以包括邻近管道的第一侧定位的第一槽，邻近管道相对的第二侧的第二槽和具有倒U形横截面的中间部分，使得中间部分配合在 管道顶部并连接第一槽和第二槽。 当管道埋设时，槽填充回填。 因此，当完全安装时，设备可以包括槽形式，带子和回填。 随着管道趋于上升，带子变形，将槽的两侧向内压缩并压缩其中的回填。 这防止了管道的进一步向上移动。

公开(公告)号：US20060223184A1

公开(公告)日：2006-10-05

申请号：US11099904

申请日：2005-04-05

Applicant: Anthony Frutos ,  Joydeep Lahiri ,  Santona Pal ,  Elizabeth Tran ,  Brian Webb

Inventor： Anthony Frutos ,  Joydeep Lahiri ,  Santona Pal ,  Elizabeth Tran ,  Brian Webb

IPC: C12N15/88 ,  C12N15/86

CPC classification number: C12N15/87

Abstract: Described herein are supports useful in incorporating biomolecules into cells and methods of making and using thereof.

Abstract translation: 本文描述的是用于将生物分子并入细胞中的支持物及其制备和使用方法。

公开(公告)号：US06376266B1

公开(公告)日：2002-04-23

申请号：US09706599

申请日：2000-11-06

Applicant: James Price Letterman, Jr. ,  Kenneth Teik Kheong Low ,  Saat Shukri Embong ,  Chee Hiong Chew ,  Boon Huat Lim ,  Aik Chong Tan ,  Albert Laninga ,  Santhiragasen al sengram Pillay ,  Michael John Seddon ,  Brian Webb

Inventor： James Price Letterman, Jr. ,  Kenneth Teik Kheong Low ,  Saat Shukri Embong ,  Chee Hiong Chew ,  Boon Huat Lim ,  Aik Chong Tan ,  Albert Laninga ,  Santhiragasen al sengram Pillay ,  Michael John Seddon ,  Brian Webb

IPC: H01L2166

CPC classification number: H01L21/568 ,  H01L21/566 ,  H01L23/3107 ,  H01L2224/45124 ,  H01L2224/45144 ,  H01L2224/45147 ,  H01L2224/48247 ,  H01L2924/01322 ,  H01L2924/10156 ,  H01L2924/12044 ,  H01L2924/181 ,  H01L2924/18165 ,  H01L2924/00 ,  H01L2924/00012 ,  H01L2924/00014

Abstract: A semiconductor package (8) with a die (10) having die pads (16) coupled to inner ends (22) of interconnects (20), the die (10) and the interconnects (20) are molded in mold compound (30) with mounting surface (12) and outer ends (24) exposed. A semiconductor die has an interconnect surface opposite the mounting surface.

Abstract translation: 具有模具（10）的半导体封装（8）被模制在模具化合物（30）中，所述模具（10）具有耦合到互连（20）的内端（22），模具（10）和互连（20）的管芯焊盘（16） 其中安装表面（12）和外端（24）暴露。 半导体管芯具有与安装表面相对的互连表面。

公开(公告)号：US6080031A

公开(公告)日：2000-06-27

申请号：US145457

申请日：1998-09-02

Applicant: Stephen P. Rogers ,  Brian Webb

Inventor： Stephen P. Rogers ,  Brian Webb

IPC: G09F9/30 ,  G09F9/00 ,  H01L51/50 ,  H01L51/52 ,  H05B33/04 ,  H05B33/10 ,  H05B33/12 ,  H05B33/14

CPC classification number: H05B33/04 ,  H01L51/5243 ,  H01L2251/566

Abstract: A method of encapsulating organic electroluminescent (EL) devices including providing an EL device on a substrate and a metallic sheet having a stand-off structure depending therefrom, the stand-off structure bounding a cavity larger than the EL device. The stand-off structure is positioned over the EL device with the EL device nested within the cavity. The metallic sheet is adhesively bonded to the substrate at a perimeter outboard of the stand-off structure to seal the organic electroluminescent device in the cavity. When a plurality of EL devices are manufactured on a single substrate, the metallic sheet is perforated at the perimeter of each device so that excess metal can be separated and the substrate separated to provide individual EL devices.

Abstract translation: 一种封装有机电致发光（EL）器件的方法，包括在衬底上提供EL器件以及具有依赖于其的支座结构的金属片，所述隔离结构限定了大于EL器件的空腔。 隔离结构位于EL器件的上方，EL器件嵌套在腔内。 金属片在支架结构的外侧的周边处与衬底粘合地结合，以密封空腔中的有机电致发光器件。 当在单个基板上制造多个EL器件时，金属片在每个器件的周边被穿孔，使得可以分离多余的金属并且将衬底分离以提供各个EL器件。

公开(公告)号：US09471086B1

公开(公告)日：2016-10-18

申请号：US14982414

申请日：2015-12-29

Applicant: Brian Webb

Inventor： Brian Webb

IPC: G05G1/08 ,  G05G5/04 ,  G05G1/04 ,  F16L55/26

CPC classification number: G05G5/04 ,  F16K11/052 ,  F16K31/602 ,  F16L41/023 ,  G05G1/04

Abstract: A switch arm assembly for a piggable pipeline connector, the assembly comprising a switch arm and a handle assembly. The handle assembly comprises shaft connecting a handle with the switch arm and a stop to prevent the shaft from moving substantially away from the switch arm should the shaft become disconnected from the switch arm. The stop may comprise a shoulder in the shaft to prevent the shaft from exiting a housing, a bonnet over the top of the handle, or both.

Abstract translation: 一种用于可拆卸管道连接器的开关臂组件，该组件包括开关臂和手柄组件。 手柄组件包括将手柄与开关臂连接的轴和止动件，以防止轴从开关臂断开时基本上远离开关臂移动。 止动件可以包括在轴中的肩部以防止轴离开壳体，帽子在手柄的顶部上，或者两者。

公开(公告)号：US20060105371A1

公开(公告)日：2006-05-18

申请号：US11261198

申请日：2005-10-27

Applicant: Ye Fang ,  Fang Lai ,  Laurent Picard ,  Brian Webb

Inventor： Ye Fang ,  Fang Lai ,  Laurent Picard ,  Brian Webb

IPC: C12Q1/70 ,  C12Q1/68

CPC classification number: C12N5/0068 ,  C12N2503/00 ,  C12N2535/10

Abstract: Methods for performing surface-mediated protein delivery into living cells, and fabricating protein-transfected cell cluster arrays are provided. The method comprises providing a protein-containing mixture; depositing said protein-containing mixture onto a surface at defined locations; affixing the protein-containing mixture to the surface as microspots; and plating cells onto the surface in sufficient density and under conditions for the proteins to be delivered into the cells. The protein-containing mixture comprises any suitable amino acid sequence, including peptides, proteins, protein-domains, antibodies, or protein-nucleic acid conjugates, etc., with a carrier reagent. Protein-transfected cell arrays may be used for rapid and direct, screening of protein or enzymatic functions or any given intracellular protein interaction in the natural environment of a living cell, as well as for high-throughput screening of other biological and chemical analytes, which affect the functions of these proteins.

公开(公告)号：US08864414B1

公开(公告)日：2014-10-21

申请号：US13933728

申请日：2013-07-02

Applicant: Brian Webb

Inventor： Brian Webb

IPC: F16L1/06 ,  F16L3/04

CPC classification number: F16L1/06

Abstract: A device for controlling buoyancy of a buried pipeline, the device comprising a form placed atop the pipeline and a flexible strap extending around the form adjacent its top. The form may comprise a first trough located adjacent the first side of the pipeline, a second trough located adjacent the opposing second side of the pipeline, and a middle section with an inverted-U-shaped cross section such that the middle portion fits over the top of the pipeline and joins the first trough and the second trough. The troughs are filled with backfill when the pipeline is buried. Thus, when fully installed, the device may comprise the slot form, the strap, and the backfill. As the pipeline tends to rise, the straps deform, bringing the sides of the troughs inward and compressing the backfill therein. This prevents further upward movement of the pipeline.

Abstract translation: 一种用于控制埋设管道浮力的装置，该装置包括放置在管道顶部的形式和围绕邻近其顶部的形式延伸的柔性带。 该形式可以包括邻近管道的第一侧定位的第一槽，邻近管道相对的第二侧的第二槽和具有倒U形横截面的中间部分，使得中间部分配合在 管道顶部并连接第一槽和第二槽。 当管道埋设时，槽填充回填。 因此，当完全安装时，设备可以包括槽形式，带子和回填。 随着管道趋于上升，带子变形，将槽的两侧向内压缩并压缩其中的回填。 这防止了管道的进一步向上移动。

公开(公告)号：US20050064600A1

公开(公告)日：2005-03-24

申请号：US10497584

申请日：2002-12-05

Applicant: Terry Clark ,  Andrew Thomas ,  Neil Shand ,  Brian Webb

Inventor： Terry Clark ,  Andrew Thomas ,  Neil Shand ,  Brian Webb

IPC: G01N31/00 ,  G01N21/35 ,  G01N31/12 ,  G01N33/00 ,  G01N33/22

CPC classification number: G01N33/0037 ,  Y02A50/245 ,  Y10T436/17

Abstract: The present invention provides a method for the detection of a material comprising ammonium nitrate and a sugar, the method comprising sensing for the presence of hydrogen isocyanate (HNCO). The present invention further provides an apparatus suitable for the examination of a material suspected of comprising ammonium nitrate and a sugar, the apparatus comprising heating means in thermal communication with a sample holder suitable for the containment of the material, the sample holder being in gaseous communication with sensing region, the apparatus being further provided with a means for inducing flow of gas from the sample holder to the sensing region and a means for sensing the presence of hydrogen isocyanate in the sensing region.

Abstract translation: 本发明提供了一种用于检测包含硝酸铵和糖的材料的方法，所述方法包括感测异氰酸氢盐（HNCO）的存在。 本发明还提供了一种适于检查怀疑含有硝酸铵和糖的材料的装置，该装置包括与适于容纳材料的样品保持器热连通的加热装置，样品保持器处于气态连通 在感测区域中，该装置还设置有用于引导气体从样品保持器流到感测区域的装置，以及用于感测感测区域中异氰酸氢盐的存在的装置。