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公开(公告)号：US20180206747A1
公开(公告)日：2018-07-26
申请号：US15826559
申请日：2017-11-29
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Derek Rinderknecht , Niema Pahlevan , Peyman Tavallali , Morteza Gharib
IPC: A61B5/024 , A61B7/04 , A61B5/02 , A61B5/026 , A61B5/0402 , A61B5/0408 , A61B5/00 , A61B7/02 , A61B5/021 , A61B5/0285
CPC classification number: A61B5/02427 , A61B5/0002 , A61B5/0059 , A61B5/02028 , A61B5/021 , A61B5/024 , A61B5/0261 , A61B5/0285 , A61B5/0402 , A61B5/0408 , A61B5/6822 , A61B5/6898 , A61B5/725 , A61B5/7275 , A61B5/742 , A61B7/02 , A61B7/04 , A61B2560/0431
Abstract: Systems and methods are provided for extracting hemodynamic information, optionally employing portable electronic devices with optional User Interface (UI) features for system implementation. The systems and methods may be employed for acquiring hemodynamic signals and associated electrophysiological data and/or analyzing the former or both in combination to yield useful physiological indicia or results. Such hardware and software is advantageously used for non-invasively monitoring cardiac health.
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公开(公告)号：US09622666B2
公开(公告)日：2017-04-18
申请号：US13715743
申请日：2012-12-14
Applicant: California Institute of Technology
Inventor： Niema Pahlevan , Morteza Gharib
CPC classification number: A61B5/021 , A61B5/02007 , A61B5/0507 , A61B5/742 , A61B8/04 , A61B8/06 , A61B8/4427 , A61B8/485 , A61B8/5223
Abstract: Hardware and software methodology are described for a non-invasive approach to blood pressure measurement in pulmonary artery and systemic arteries by using wall displacement and blood velocity that are measured using ultrasound, microwave techniques and/or other radiofrequency (RF) techniques.
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公开(公告)号：US20130178736A1
公开(公告)日：2013-07-11
申请号：US13715743
申请日：2012-12-14
Applicant: California Institute of Technology
Inventor： Niema Pahlevan , Morteza Gharib
CPC classification number: A61B5/021 , A61B5/02007 , A61B5/0507 , A61B5/742 , A61B8/04 , A61B8/06 , A61B8/4427 , A61B8/485 , A61B8/5223
Abstract: Hardware and software methodology are described for a non-invasive approach to blood pressure measurement in pulmonary artery and systemic arteries by using wall displacement and blood velocity that are measured using ultrasound, microwave techniques and/or other radiofrequency (RF) techniques.
Abstract translation: 描述了通过使用超声波，微波技术和/或其他射频（RF）技术测量的壁位移和血液速度来描述肺动脉和全身动脉血压测量的非侵入性方法的硬件和软件方法。
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公开(公告)号：US20170258343A1
公开(公告)日：2017-09-14
申请号：US15598968
申请日：2017-05-18
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Niema Pahlevan , Peyman Tavallali , Thomas Yizhao Hou , Morteza Gharib
CPC classification number: A61B5/02416 , A61B5/0004 , A61B5/0013 , A61B5/0077 , A61B5/02028 , A61B5/02405 , A61B5/02438 , A61B5/0507 , A61B5/7235 , A61B5/7278 , A61B5/7282 , A61B5/746 , A61B8/02 , A61B8/06 , A61B8/5223 , A61B8/565
Abstract: Hardware and software methodology are described for cardiac health measurement. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. The intrinsic frequencies provide metrics/ measures that correlate to the cardiac health of the subject. The systems may be used for monitoring a condition and/or is diagnosis. Exemplary uses include identifying (diagnosing) the presence of arrhythmia, heat failure, atrial fibrillation, aneurysms, vessel stenosis or aortic valve dysfunction and the necessity for valve replacement and/or monitoring congestive heart failure progression, together with identifying the acute need for hospitalization in connection with daily testing for any such condition.
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公开(公告)号：US20170020400A1
公开(公告)日：2017-01-26
申请号：US15199160
申请日：2016-06-30
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Derek Rinderknecht , Morteza Gharib , Niema Pahlevan , Peyman Tavallali
CPC classification number: A61B5/02438 , A61B5/02416 , A61B5/6822 , A61B5/6824 , A61B5/6826 , A61B5/6831 , A61B5/6833 , A61B7/00 , A61B7/04 , A61B2562/0204 , A61B2562/0223
Abstract: Devices, systems, and methods are described for acquiring heart sound timing content to enhance pulse waveform analysis.
Abstract translation: 描述了用于获取心音定时内容以增强脉搏波形分析的装置，系统和方法。
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Patent Agency Ranking
公开(公告)号：US20150201883A1
公开(公告)日：2015-07-23
申请号：US14602133
申请日：2015-01-21
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Danny Petrasek , Niema Pahlevan , Morteza Gharib
CPC classification number: A61B5/7235 , A61B5/02007 , A61B5/02108 , A61B5/6898 , A61B5/7246
Abstract: Systems, devices, and methods are described in which Intrinsic Frequency calculation (direct and/or by approximation) of a pulse pressure waveform is used make a determination of metabolic syndrome and/or insulin resistance or sensitivity. The pulse pressure waveform may be obtained non-invasively using a smartphone platform or be otherwise obtained.
Abstract translation: 描述了使用脉冲压力波形的本征频率计算（直接和/或通过近似）来进行代谢综合征和/或胰岛素抵抗或灵敏度的确定的系统，装置和方法。 可以使用智能手机平台非侵入地获得脉压压力波形或以其他方式获得。
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公开(公告)号：US09026193B2
公开(公告)日：2015-05-05
申请号：US13725039
申请日：2012-12-21
Applicant: California Institute of Technology
Inventor： Niema Pahlevan , Peyman Tavallali , Thomas Yizhao Hou , Morteza Gharib
CPC classification number: A61B5/02416 , A61B5/0004 , A61B5/0013 , A61B5/0077 , A61B5/02028 , A61B5/02405 , A61B5/02438 , A61B5/0507 , A61B5/7235 , A61B5/7278 , A61B5/7282 , A61B5/746 , A61B8/02 , A61B8/06 , A61B8/5223 , A61B8/565
Abstract: Hardware and software methodology are described for cardiac health measurement. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. The intrinsic frequencies provide metrics/measures that correlate to the cardiac health of the subject. The systems may be used for monitoring a condition and/or is diagnosis. Exemplary uses include identifying (diagnosing) the presence of arrhythmia, heat failure, atrial fibrillation, aneurysms, vessel stenosis or aortic valve dysfunction and the necessity for valve replacement and/or monitoring congestive heart failure progression, together with identifying the acute need for hospitalization in connection with daily testing for any such condition.
Abstract translation: 描述了用于心脏健康测量的硬件和软件方法。 分析针对受试者各种获得的血流动力学波形，以计算或近似跨越Dicrotic Notch的两个域中的两个域中的固有频率。 固有频率提供与受试者的心脏健康相关的度量/措施。 该系统可用于监测病症和/或诊断。 示例性用途包括识别（诊断）心律不齐，热衰竭，心房颤动，动脉瘤，血管狭窄或主动脉瓣功能障碍的存在以及瓣膜置换和/或监测充血性心力衰竭进展的必要性，以及确定急性住院需要 与任何此类状况的日常测试连接。
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公开(公告)号：US10918291B2
公开(公告)日：2021-02-16
申请号：US15826559
申请日：2017-11-29
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Derek Rinderknecht , Niema Pahlevan , Peyman Tavallali , Morteza Gharib
IPC: A61B5/024 , A61B5/0408 , A61B5/026 , A61B5/0402 , A61B5/02 , A61B5/00 , A61B7/04 , A61B7/02 , A61B5/0285 , A61B5/021
Abstract: Systems and methods are provided for extracting hemodynamic information, optionally employing portable electronic devices with optional User Interface (UI) features for system implementation. The systems and methods may be employed for acquiring hemodynamic signals and associated electrophysiological data and/or analyzing the former or both in combination to yield useful physiological indicia or results. Such hardware and software is advantageously used for non-invasively monitoring cardiac health.
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公开(公告)号：US20170181643A1
公开(公告)日：2017-06-29
申请号：US15459581
申请日：2017-03-15
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Niema Pahlevan , Morteza Gharib
CPC classification number: A61B5/021 , A61B5/02007 , A61B5/0507 , A61B5/742 , A61B8/04 , A61B8/06 , A61B8/4427 , A61B8/485 , A61B8/5223
Abstract: Hardware and software methodology are described for a non-invasive approach to blood pressure measurement in pulmonary artery and systemic arteries by using wall displacement and blood velocity that are measured using ultrasound, microwave techniques and/or other radiofrequency (RF) techniques.
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10.发明申请INTRINSIC FREQUENCY ANALYSIS FOR LEFT VENTRICLE EJECTION FRACTION OR STROKE VOLUME DETERMINATION 审中-公开用于左心室射血分数或排气量测定的内在频率分析公开(公告)号：US20170020414A1
公开(公告)日：2017-01-26
申请号：US15279246
申请日：2016-09-28
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Niema Pahlevan , Peyman Tavallali , Derek Rinderknecht , Morteza Gharib
CPC classification number: A61B5/1128 , A61B5/0004 , A61B5/0013 , A61B5/02028 , A61B5/021 , A61B5/02405 , A61B5/0261 , A61B5/029 , A61B5/1102 , A61B5/7235 , A61B5/7278 , A61B5/7282 , A61B8/065 , A61B8/5223 , A61B2562/0228
Abstract: Hardware and software methodology are described for non-invasively monitoring cardiac health. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. Together with associated notch timing, heart rate and blood pressure values left ventricle ejection fraction and/or stroke volume can be determination.
Abstract translation: 硬件和软件方法被描述为非侵入性地监测心脏健康。 分析针对受试者各种获得的血流动力学波形，以计算或近似跨越Dicrotic Notch的两个域中的两个域中的固有频率。 与相关的切口定时一起，可以确定心率和血压值左心室射血分数和/或冲程体积。
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