-
公开(公告)号：US20060068378A1
公开(公告)日：2006-03-30
申请号：US11050983
申请日：2005-02-04
申请人： Chad Mirkin , Robert Letsinger , Robert Mucic , James Storhoff , Robert Elghanian , Thomas Taton , Viswanadham Garimella , Zhi Li , So-Jung Park , Gang Lu
发明人： Chad Mirkin , Robert Letsinger , Robert Mucic , James Storhoff , Robert Elghanian , Thomas Taton , Viswanadham Garimella , Zhi Li , So-Jung Park , Gang Lu
CPC分类号： B82Y30/00 , B01J2219/00274 , B01J2219/005 , B01J2219/00585 , B01J2219/00596 , B01J2219/00603 , B01J2219/00648 , B01J2219/00653 , B01J2219/00659 , B01J2219/00702 , B01J2219/00722 , B82B1/00 , B82Y15/00 , C07B2200/11 , C07H21/00 , C12Q1/6816 , C12Q1/6825 , C12Q1/6827 , C12Q1/6834 , C12Q1/6837 , C40B40/06 , Y10S977/924 , C12Q2563/155 , C12Q2563/143 , C12Q2537/143 , C12Q2525/197 , C12Q2525/161 , C12Q2565/625 , C12Q2537/125 , C12Q2565/519 , C12Q2565/515
摘要： The invention provides methods of detecting a nucleic acid. The methods comprise contacting the nucleic acid with one or more types of particles having oligonucleotides attached thereto. In one embodiment of the method, the oligonucleotides are attached to nanoparticles and have sequences complementary to portions of the sequence of the nucleic acid. A detectable change (preferably a color change) is brought about as a result of the hybridization of the oligonucleotides on the nanoparticles to the nucleic acid. The invention also provides compositions and kits comprising particles. The invention further provides methods of synthesizing unique nanoparticle-oligonucleotide conjugates, the conjugates produced by the methods, and methods of using the conjugates. In addition, the invention provides nanomaterials and nanostructures comprising nanoparticles and methods of nanofabrication utilizing nanoparticles. Finally, the invention provides a method of separating a selected nucleic acid from other nucleic acids.
-
公开(公告)号：US20070059732A1
公开(公告)日：2007-03-15
申请号：US11445815
申请日：2006-06-01
申请人： Cynthia Bamdad , Robert Mucic
发明人： Cynthia Bamdad , Robert Mucic
CPC分类号： G01N27/3275 , B01J13/00 , B82Y15/00 , B82Y30/00 , C12Q1/6825 , G01N27/3277 , G01N27/48 , Y10S977/773 , Y10S977/92 , Y10T436/143333 , C12Q2565/1015 , C12Q2525/313 , C12Q2525/197 , C12Q2565/101 , C12Q2563/113
摘要： The invention relates to the use of particles comprising binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter composition are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence or absence of the target analyte to be determined.
摘要翻译： 本发明涉及包含结合配体和电子转移部分（ETM）的颗粒的用途。 当目标分析物结合时，颗粒和报道组合物被结合并传送到电极表面。 然后检测ETM，允许确定目标分析物的存在或不存在。
-
公开(公告)号：US07863035B2
公开(公告)日：2011-01-04
申请号：US12032356
申请日：2008-02-15
申请人： Charles E. Clemens , Robert Mucic , Rudolph A. Montalvo , Clark Foster , Gary R. Gust , Thomas P. Robinson , Gary T. Olsen
发明人： Charles E. Clemens , Robert Mucic , Rudolph A. Montalvo , Clark Foster , Gary R. Gust , Thomas P. Robinson , Gary T. Olsen
CPC分类号： G01N27/27 , B01L3/502707 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L7/52 , B01L7/525 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0684 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0867 , B01L2300/0874 , B01L2300/088 , B01L2300/0887 , B01L2300/123 , B01L2300/1827 , B01L2400/0439 , B01L2400/0442 , B01L2400/0478 , B01L2400/0481 , B01L2400/0487 , B01L2400/0605 , B01L2400/0655
摘要： The invention relates to fluidics as used in medical and diagnostic equipment and relates further to means for purifying, abstracting, filtering, detecting and/or measuring analytes in liquid samples.
摘要翻译： 本发明涉及用于医疗和诊断设备中的流体学，并且还涉及用于净化，抽取，过滤，检测和/或测量液体样品中的分析物的装置。
-
公开(公告)号：US09086371B2
公开(公告)日：2015-07-21
申请号：US13551403
申请日：2012-07-17
申请人： Charles E Clemens , Robert Mucic , Rudolph A. Montalvo , Clark Foster , Gary R. Gust , Thomas P. Robinson , Gary T. Olsen
发明人： Charles E Clemens , Robert Mucic , Rudolph A. Montalvo , Clark Foster , Gary R. Gust , Thomas P. Robinson , Gary T. Olsen
CPC分类号： G01N27/27 , B01L3/502707 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L7/52 , B01L7/525 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0684 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0867 , B01L2300/0874 , B01L2300/088 , B01L2300/0887 , B01L2300/123 , B01L2300/1827 , B01L2400/0439 , B01L2400/0442 , B01L2400/0478 , B01L2400/0481 , B01L2400/0487 , B01L2400/0605 , B01L2400/0655
摘要： The invention relates to fluidics as used in medical and diagnostic equipment and relates further to means for purifying, abstracting, filtering, detecting and/or measuring analytes in liquid samples.
摘要翻译： 本发明涉及用于医疗和诊断设备中的流体学，并且还涉及用于净化，抽取，过滤，检测和/或测量液体样品中的分析物的装置。
-
公开(公告)号：US20130137591A1
公开(公告)日：2013-05-30
申请号：US13551403
申请日：2012-07-17
申请人： Charles E. Clemens , Robert Mucic , Rudolph A. Montalvo , Clark Foster , Gary R. Gust , Thomas P. Robinson , Gary T. Olsen
发明人： Charles E. Clemens , Robert Mucic , Rudolph A. Montalvo , Clark Foster , Gary R. Gust , Thomas P. Robinson , Gary T. Olsen
IPC分类号： G01N27/27
CPC分类号： G01N27/27 , B01L3/502707 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L7/52 , B01L7/525 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0684 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0867 , B01L2300/0874 , B01L2300/088 , B01L2300/0887 , B01L2300/123 , B01L2300/1827 , B01L2400/0439 , B01L2400/0442 , B01L2400/0478 , B01L2400/0481 , B01L2400/0487 , B01L2400/0605 , B01L2400/0655
摘要： The invention relates to fluidics as used in medical and diagnostic equipment and relates further to means for purifying, abstracting, filtering, detecting and/or measuring analytes in liquid samples.
-
公开(公告)号：US20090291507A1
公开(公告)日：2009-11-26
申请号：US12534681
申请日：2009-08-03
申请人： Charles E. Clemmens , Robert Mucic , Rudolph A. Montalvo , Clark Foster , Gary R. Gust , Thomas P. Robinson , Gary T. Olsen
发明人： Charles E. Clemmens , Robert Mucic , Rudolph A. Montalvo , Clark Foster , Gary R. Gust , Thomas P. Robinson , Gary T. Olsen
CPC分类号： G01N27/27 , B01L3/502707 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L7/52 , B01L7/525 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0684 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0867 , B01L2300/0874 , B01L2300/088 , B01L2300/0887 , B01L2300/123 , B01L2300/1827 , B01L2400/0439 , B01L2400/0442 , B01L2400/0478 , B01L2400/0481 , B01L2400/0487 , B01L2400/0605 , B01L2400/0655
摘要： The invention relates to fluidics as used in medical and diagnostic equipment and relates further to means for purifying, abstracting, filtering, detecting and/or measuring analytes in liquid samples.
摘要翻译： 本发明涉及用于医疗和诊断设备中的流体学，并且还涉及用于净化，抽取，过滤，检测和/或测量液体样品中的分析物的装置。
-
公开(公告)号：US20080200343A1
公开(公告)日：2008-08-21
申请号：US12032356
申请日：2008-02-15
申请人： Charles E. Clemens , Robert Mucic , Rudolph A. Montalvo , Clark Foster , Gary R. Gust , Thomas P. Robinson , Gary T. Olsen
发明人： Charles E. Clemens , Robert Mucic , Rudolph A. Montalvo , Clark Foster , Gary R. Gust , Thomas P. Robinson , Gary T. Olsen
IPC分类号： C40B30/04 , B01J19/00 , C40B40/00 , C40B40/08 , F16K27/00 , G01N33/487 , C40B40/10 , G01N21/76
CPC分类号： G01N27/27 , B01L3/502707 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L7/52 , B01L7/525 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0684 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0636 , B01L2300/0645 , B01L2300/0816 , B01L2300/0867 , B01L2300/0874 , B01L2300/088 , B01L2300/0887 , B01L2300/123 , B01L2300/1827 , B01L2400/0439 , B01L2400/0442 , B01L2400/0478 , B01L2400/0481 , B01L2400/0487 , B01L2400/0605 , B01L2400/0655
摘要： The invention relates to fluidics as used in medical and diagnostic equipment and relates further to means for purifying, abstracting, filtering, detecting and/or measuring analytes in liquid samples.
摘要翻译： 本发明涉及用于医疗和诊断设备中的流体学，并且还涉及用于净化，抽取，过滤，检测和/或测量液体样品中的分析物的装置。
-
-
-
-
-
-
搜索结果
7 条记录 (耗时 0.064 秒)
