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1.发明申请METHODS TO AVOID FREQUENCY LOCKING IN A MULTI-CHANNEL NEUROSTIMULATION SYSTEM USING PULSE SHIFTING 有权使用脉冲移位在多通道神经网络系统中避免频率锁定的方法公开(公告)号：US20110054567A1
公开(公告)日：2011-03-03
申请号：US12550213
申请日：2009-08-28
申请人： Courtney Lane , Rafael Carbunaru , Kerry Bradley , David K.L. Peterson , Andrew DiGiore , Michael Moffitt
发明人： Courtney Lane , Rafael Carbunaru , Kerry Bradley , David K.L. Peterson , Andrew DiGiore , Michael Moffitt
IPC分类号： A61N1/08
CPC分类号： A61N1/36021 , A61B5/021 , A61B5/024 , A61B5/02405 , A61B5/04004 , A61B5/0488 , A61B5/1118 , A61B5/112 , A61B5/4812 , A61B5/4836 , A61M5/1723 , A61N1/0529 , A61N1/08 , A61N1/306 , A61N1/36025 , A61N1/36031 , A61N1/36034 , A61N1/3605 , A61N1/3606 , A61N1/36062 , A61N1/36071 , A61N1/36082 , A61N1/36103 , A61N1/36135 , A61N1/36171 , A61N1/36178
摘要： A method and neurostimulation system for treating a patient are provided. A plurality of pulsed electrical waveforms are respectively delivered within a plurality of timing channels of the neurostimulation system, thereby treating the patient. Sets of stimulation pulses within the pulsed electrical waveforms that will potentially overlap temporally are predicted. Stimulation pulses in the respective pulsed electrical waveforms are temporally shifted in a manner that prevents overlap of the potentially overlapping pulse sets while preventing frequency locking between the timing channels.
摘要翻译： 提供了一种用于治疗患者的方法和神经刺激系统。 多个脉冲电波形分别在神经刺激系统的多个定时通道内递送，从而治疗患者。 可以预测脉冲电波形内可能在时间上重叠的一组刺激脉冲。 相应脉冲电波形中的刺激脉冲以防止可能重叠的脉冲组重叠的方式在时间上移位，同时防止定时通道之间的频率锁定。
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2.发明申请METHODS TO AVOID FREQUENCY LOCKING IN A MULTI-CHANNEL NEUROSTIMULATION SYSTEM USING PULSE PLACEMENT 有权使用脉冲放置在多通道神经元系统中避免频率锁定的方法公开(公告)号：US20110054568A1
公开(公告)日：2011-03-03
申请号：US12550237
申请日：2009-08-28
申请人： Courtney Lane , Rafael Carbunaru , Kerry Bradley , David K.L. Peterson , Andrew DiGiore , Michael Moffitt
发明人： Courtney Lane , Rafael Carbunaru , Kerry Bradley , David K.L. Peterson , Andrew DiGiore , Michael Moffitt
CPC分类号： A61N1/08 , A61N1/36071 , A61N1/36082
摘要： A method and neurostimulation system for treating a patient are provided. A plurality of pulsed electrical waveforms are respectively delivered within a plurality of timing channels of the neurostimulation system, thereby treating the patient. Sets of stimulation pulses within the electrical waveforms that will potentially overlap temporally are predicted. Each of the potentially overlapping pulse sets is substituted with a replacement stimulation pulse, such that each replacement stimulation pulse is delivered within at least one of the respective timing channels, thereby preventing temporal overlap between the stimulation pulses of the respective electrical waveforms while preventing frequency locking between the timing channels.
摘要翻译： 提供了一种用于治疗患者的方法和神经刺激系统。 多个脉冲电波形分别在神经刺激系统的多个定时通道内递送，从而治疗患者。 预测可能在时间上潜在重叠的电波形内的一组刺激脉冲。 每个可能重叠的脉冲组被替换刺激脉冲代替，使得每个替换刺激脉冲在相应的定时通道中的至少一个内递送，从而防止各个电波形的刺激脉冲之间的时间重叠，同时防止频率锁定 在定时通道之间。
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公开(公告)号：US20110160796A1
公开(公告)日：2011-06-30
申请号：US12976658
申请日：2010-12-22
CPC分类号： A61N1/36139 , A61N1/0531 , A61N1/0534 , A61N1/36082 , A61N1/37282
摘要： Neurostimulation systems and methods for providing therapy to a patient suffering from a symptom of a disease that latently responds to electrical stimulation therapy are provided. First electrical stimulation energy is conveyed to or from a tissue region of the patient in accordance with a first set of stimulation parameters, thereby affecting the symptom. A predetermined period of time estimated for the symptom to resolve in response to electrical stimulation therapy is allowed to elapse. Second electrical stimulation energy is conveyed to or from the tissue region in accordance with a second set of stimulation parameters different from the first set of stimulation parameters.
摘要翻译： 提供了神经刺激系统和用于向患有潜在的电刺激治疗反应的疾病症状的患者提供治疗的方法。 根据第一组刺激参数将第一电刺激能量传送到患者的组织区域或从患者的组织区域传送，从而影响症状。 对于电刺激治疗反应的症状的预定时间段被允许经过。 根据与第一组刺激参数不同的第二组刺激参数将第二电刺激能量传送到组织区域或从组织区域传送。
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4.发明申请IMPLANTABLE MEDICAL DEVICE THAT USES ELECTRICAL CURRENT STEERING BY MEANS OF OUTPUT IMPEDANCE MODULATION 有权通过输出阻抗调制方式使用电流转向的可植入医疗器械公开(公告)号：US20100125315A1
公开(公告)日：2010-05-20
申请号：US12606065
申请日：2009-10-26
IPC分类号： A61N1/00
CPC分类号： A61N1/36125 , A61N1/0551 , A61N1/36157 , A61N1/36185
摘要： A method and system of providing therapy to a patient implanted with an array of electrodes is provided. Electrical stimulation current is conveyed from at least two of the electrodes to at least one of the electrodes along at least two electrical paths through tissue of the patient, and the electrical stimulation current is shifted between the electrical paths by actively adjusting one or more finite resistances respectively associated with one or more of the electrical paths.
摘要翻译： 提供了向植入电极阵列的患者提供治疗的方法和系统。 电刺激电流沿着沿着患者组织的至少两条电路径从至少两个电极传送到至少一个电极，并且电刺激电流通过主动调节一个或多个有限电阻而在电路径之间移动 分别与一个或多个电路径相关联。
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5.发明申请ANCHORING UNITS FOR LEADS OF IMPLANTABLE ELECTRIC STIMULATION SYSTEMS AND METHODS OF MAKING AND USING 有权可植入电刺激系统引导锚固单元及其制造和使用方法公开(公告)号：US20110295330A1
公开(公告)日：2011-12-01
申请号：US13207876
申请日：2011-08-11
CPC分类号： A61N1/0558
摘要： A nerve stimulation lead has a distal end, a proximal end, and a longitudinal length. The nerve stimulation lead includes a plurality of electrodes disposed at the distal end, a plurality of terminals disposed at the proximal end, and a plurality of conductive wires electrically coupling the plurality of electrodes electrically to the plurality of terminals. The nerve stimulation lead also includes at least one anchoring unit disposed on the nerve stimulation lead. The at least one anchoring unit is configured and arranged for anchoring the nerve stimulation lead against a bony structure.
摘要翻译： 神经刺激引线具有远端，近端和纵向长度。 神经刺激引线包括设置在远端的多个电极，设置在近端的多个端子，以及将多个电极电连接到多个端子的多个导线。 神经刺激引线还包括设置在神经刺激引线上的至少一个锚定单元。 所述至少一个锚定单元被配置和布置成用于将神经刺激引线抵靠骨结构锚定。
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6.发明申请ANCHORING UNITS FOR LEADS OF IMPLANTABLE ELECTRIC STIMULATION SYSTEMS AND METHODS OF MAKING AND USING 有权可植入电刺激系统引导锚固单元及其制造和使用方法公开(公告)号：US20090248095A1
公开(公告)日：2009-10-01
申请号：US12413081
申请日：2009-03-27
CPC分类号： A61N1/0558
摘要： A nerve stimulation lead has a distal end, a proximal end, and a longitudinal length. The nerve stimulation lead includes a plurality of electrodes disposed at the distal end, a plurality of terminals disposed at the proximal end, and a plurality of conductive wires electrically coupling the plurality of electrodes electrically to the plurality of terminals. The nerve stimulation lead also includes at least one anchoring unit disposed on the nerve stimulation lead. The at least one anchoring unit is configured and arranged for anchoring the nerve stimulation lead against a bony structure.
摘要翻译： 神经刺激引线具有远端，近端和纵向长度。 神经刺激引线包括设置在远端的多个电极，设置在近端的多个端子，以及将多个电极电连接到多个端子的多个导线。 神经刺激引线还包括设置在神经刺激引线上的至少一个锚定单元。 所述至少一个锚定单元被配置和布置成用于将神经刺激引线抵靠骨结构锚定。
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7.发明授权Methods to avoid frequency locking in a multi-channel neurostimulation system using pulse placement 有权使用脉冲放置避免频率锁定在多通道神经刺激系统中的方法公开(公告)号：US08543200B2
公开(公告)日：2013-09-24
申请号：US12550237
申请日：2009-08-28
申请人： Courtney Lane , Rafael Carbunaru , Kerry Bradley , David K. L. Peterson , Andrew DiGiore , Michael Moffitt
发明人： Courtney Lane , Rafael Carbunaru , Kerry Bradley , David K. L. Peterson , Andrew DiGiore , Michael Moffitt
IPC分类号： A61N1/00
CPC分类号： A61N1/08 , A61N1/36071 , A61N1/36082
摘要： A method and neurostimulation system for treating a patient are provided. A plurality of pulsed electrical waveforms are respectively delivered within a plurality of timing channels of the neurostimulation system, thereby treating the patient. Sets of stimulation pulses within the electrical waveforms that will potentially overlap temporally are predicted. Each of the potentially overlapping pulse sets is substituted with a replacement stimulation pulse, such that each replacement stimulation pulse is delivered within at least one of the respective timing channels, thereby preventing temporal overlap between the stimulation pulses of the respective electrical waveforms while preventing frequency locking between the timing channels.
摘要翻译： 提供了一种用于治疗患者的方法和神经刺激系统。 多个脉冲电波形分别在神经刺激系统的多个定时通道内递送，从而治疗患者。 预测可能在时间上潜在重叠的电波形内的一组刺激脉冲。 每个可能重叠的脉冲组被替换刺激脉冲代替，使得每个替换刺激脉冲在相应的定时通道中的至少一个内递送，从而防止各个电波形的刺激脉冲之间的时间重叠，同时防止频率锁定 在定时通道之间。
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公开(公告)号：US08731686B2
公开(公告)日：2014-05-20
申请号：US12630761
申请日：2009-12-03
申请人： Courtney Lane , Jesse Geroy , James C. Makous , Todd Whitehurst , Matthew Flowers , John Michael Barker , Terry Ferrell , John Swoyer , Brett Schleicher , Jeff Gagnon , Andrew DiGiore , Ellis Garai , Kristen Jaax , Rafael Carbunaru
发明人： Courtney Lane , Jesse Geroy , James C. Makous , Todd Whitehurst , Matthew Flowers , John Michael Barker , Terry Ferrell , John Swoyer , Brett Schleicher , Jeff Gagnon , Andrew DiGiore , Ellis Garai , Kristen Jaax , Rafael Carbunaru
IPC分类号： A61N1/00
CPC分类号： A61B17/0057 , A61B90/10 , A61B2090/103 , A61N1/0534 , A61N1/0539
摘要： A burr hole plug comprises a plug base configured for being mounted around a burr hole. The plug base includes an aperture through which an elongated medical device exiting the burr hole may pass. The burr hole plug further comprises a retainer configured for being mounted within the aperture of the plug base. The retainer further includes first and second slidable clamping mechanisms configured for securing the medical devices therebetween within the aperture of the plug base. A method comprises introducing the medical device through the burr hole, mounting a plug base around the burr hole, such that the medical device extends through the plug base aperture, mounting the retainer within the aperture of the plug base, and sliding the first and second clamping mechanisms secure the medical device therebetween.
摘要翻译： 毛刺孔塞包括构造成围绕钻孔安装的塞子基座。 插头基座包括一个孔，通过该孔可以使离开钻孔的细长医疗装置通过。 毛刺孔塞还包括保持器，其构造成用于安装在插头基座的孔内。 保持器还包括第一和第二可滑动夹紧机构，其被构造用于将医疗装置固定在插头基座的孔内。 一种方法包括：通过毛刺孔引导医疗装置，将插头基座安装在毛刺孔周围，使得医疗装置延伸穿过插头基座孔口，将保持器安装在插头基座的孔内，并将第一和第二 夹紧机构将医疗装置固定在其间。
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9.发明授权Anchoring units for leads of implantable electric stimulation systems and methods of making and using 有权可植入电刺激系统的引导锚定单元及其制作和使用方法公开(公告)号：US08224460B2
公开(公告)日：2012-07-17
申请号：US13207876
申请日：2011-08-11
IPC分类号： A61N1/00
CPC分类号： A61N1/0558
摘要： A nerve stimulation lead has a distal end, a proximal end, and a longitudinal length. The nerve stimulation lead includes a plurality of electrodes disposed at the distal end, a plurality of terminals disposed at the proximal end, and a plurality of conductive wires electrically coupling the plurality of electrodes electrically to the plurality of terminals. The nerve stimulation lead also includes at least one anchoring unit disposed on the nerve stimulation lead. The at least one anchoring unit is configured and arranged for anchoring the nerve stimulation lead against a bony structure.
摘要翻译： 神经刺激引线具有远端，近端和纵向长度。 神经刺激引线包括设置在远端的多个电极，设置在近端的多个端子，以及将多个电极电连接到多个端子的多个导线。 神经刺激引线还包括设置在神经刺激引线上的至少一个锚定单元。 所述至少一个锚定单元被配置和布置成用于将神经刺激引线抵靠骨结构锚定。
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10.发明授权Anchoring units for leads of implantable electric stimulation systems and methods of making and using 有权可植入电刺激系统的引导锚定单元及其制作和使用方法公开(公告)号：US08019443B2
公开(公告)日：2011-09-13
申请号：US12413081
申请日：2009-03-27
IPC分类号： A61N1/00
CPC分类号： A61N1/0558
摘要： A nerve stimulation lead has a distal end, a proximal end, and a longitudinal length. The nerve stimulation lead includes a plurality of electrodes disposed at the distal end, a plurality of terminals disposed at the proximal end, and a plurality of conductive wires electrically coupling the plurality of electrodes electrically to the plurality of terminals. The nerve stimulation lead also includes at least one anchoring unit disposed on the nerve stimulation lead. The at least one anchoring unit is configured and arranged for anchoring the nerve stimulation lead against a bony structure.
摘要翻译： 神经刺激引线具有远端，近端和纵向长度。 神经刺激引线包括设置在远端的多个电极，设置在近端的多个端子，以及将多个电极电连接到多个端子的多个导线。 神经刺激引线还包括设置在神经刺激引线上的至少一个锚定单元。 所述至少一个锚定单元被配置和布置成用于将神经刺激引线抵靠骨结构锚定。
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