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    Apparatus and method for conducting large scale clinical trials
    1.
    发明申请
    Apparatus and method for conducting large scale clinical trials 审中-公开
    用于进行大规模临床试验的装置和方法

    公开(公告)号：US20070005393A1

    公开(公告)日：2007-01-04

    申请号：US11170297

    申请日：2005-06-29

    申请人： Curtis Cole ,  Nikiforos Kollias ,  Gregory Payonk

    发明人： Curtis Cole ,  Nikiforos Kollias ,  Gregory Payonk

    IPC分类号： G06Q10/00 ,  A61B5/00

    CPC分类号： G06Q50/22 ,  G16H10/20

    摘要： A system for conducting large scale clinical trials has a plurality of data collection nodes for collecting data from subjects participating in the clinical trial. A data analysis facility is located remotely from the data collection nodes and the data is communicated from the data collection nodes to the data analysis facility, where it is stored and analyzed. Each data collection node may include testing and data entry facilities, e.g., in the form of photographic equipment or various diagnostic and measuring probes, such as those used to measure skin color, elasticity and moisture content. The data nodes may be operated by the participant.

    摘要翻译： 进行大规模临床试验的系统具有多个数据收集节点，用于收集参与临床试验的受试者的数据。 数据分析设备远离数据收集节点，数据从数据收集节点传送到数据分析设备，在那里进行存储和分析。 每个数据收集节点可以包括测试和数据输入设施，例如以照相设备或各种诊断和测量探针的形式，例如用于测量皮肤颜色，弹性和水分含量的那些。 数据节点可以由参与者操作。

    Handheld device for determining skin age, proliferation status and photodamage level
    2.
    发明申请
    Handheld device for determining skin age, proliferation status and photodamage level 审中-公开
    用于确定皮肤年龄，增殖状态和光损伤水平的手持设备

    公开(公告)号：US20070004972A1

    公开(公告)日：2007-01-04

    申请号：US11170129

    申请日：2005-06-29

    申请人： Curtis Cole ,  Nikiforos Kollias ,  Frederick Hartman

    发明人： Curtis Cole ,  Nikiforos Kollias ,  Frederick Hartman

    IPC分类号： A61B5/00

    CPC分类号： A61B5/442 ,  A61B5/0059 ,  A61B5/0071

    摘要： A self-contained, handheld probe for measuring at least one parameter of skin condition, has one or more light sources that may be used to project light upon the skin. The light projected is of a selected wavelength known to generate a specific fluorescence that is indicative of the skin parameter of interest in accordance with a known correlation. To produce the proper excitation light, a light source generating that wavelength is used or a broader spectrum of light is selectively filtered to pass the wavelength of interest. Lenses, fiber optic elements or waveguides may be employed to project the light onto the skin at a specific location and/or to deliver the skin response to a light detector, which measures the light signal from the skin. and generates an output signal indicative of the value of the at least one parameter. The probe may be used to measure skin age, photodamage and/or proliferation.

    摘要翻译： 用于测量皮肤状况至少一个参数的独立式手持式探头具有一个或多个可用于将光投射到皮肤上的光源。 所投射的光具有已知的选择波长，以根据已知的相关性产生指示感兴趣的皮肤参数的特定荧光。 为了产生适当的激发光，使用产生该波长的光源或选择性地过滤较宽光谱以通过感兴趣的波长。 可以使用透镜，光纤元件或波导将光投射到特定位置处的皮肤上和/或将光皮肤响应递送到光检测器，光检测器测量来自皮肤的光信号。 并且产生指示所述至少一个参数的值的输出信号。 探针可用于测量皮肤年龄，光损伤和/或增殖。

    APPARATUS HAVING A FIBROUS SKIN-CONTACTABLE ELEMENT CONTAINING AN AGENT
    6.
    发明申请
    APPARATUS HAVING A FIBROUS SKIN-CONTACTABLE ELEMENT CONTAINING AN AGENT 审中-公开
    具有包含代理商的纤维皮肤接触元件的装置

    公开(公告)号：US20090149822A1

    公开(公告)日：2009-06-11

    申请号：US12336809

    申请日：2008-12-17

    申请人： Gregory Skover ,  Curtis Cole ,  Elvin Lukenbach

    发明人： Gregory Skover ,  Curtis Cole ,  Elvin Lukenbach

    IPC分类号： A61M35/00

    CPC分类号： A61B17/54 ,  A45D34/04 ,  A45D2200/207 ,  A61B2017/00747 ,  A61B2017/00761 ,  A61H7/004 ,  A61H7/005 ,  A61H15/02 ,  A61H2201/105 ,  A61K8/41 ,  A61K8/64 ,  A61K8/671 ,  A61K8/97 ,  A61K31/07 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08

    摘要： The invention features an apparatus for delivering mechanical energy to an expanse of skin, wherein the apparatus includes: (a) a skin-contactable element having a skin-contactable surface, wherein the skin-contactable element includes an agent selected from the group consisting of a benefit agent, an apparatus-enhancing agent, and combinations thereof; (b) a motor; and (c) a transfer member for transferring mechanical energy from the motor to the skin-contactable element in order to provide periodic motion to the skin-contactable surface; wherein the agent is configured to release from the skin contactable element to the expanse of skin upon contacting the skin-contactable surface with the expanse of skin.

    摘要翻译： 本发明的特征在于一种用于将机械能递送到一大片皮肤的装置，其中所述装置包括：（a）具有皮肤可接触表面的皮肤接触元件，其中所述皮肤接触元件包括选自以下的试剂： 有益剂，装置增强剂及其组合; （b）电机; 和（c）用于将机械能从马达传递到皮肤接触元件的转移构件，以便向皮肤接触表面提供周期性运动; 其中所述试剂构造成在将所述皮肤接触表面与所述皮肤接触的表面接触时从所述皮肤可接触元件释放到所述皮肤层。