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    Systems using cell culture for production of isoprene
    1.
    发明授权
    Systems using cell culture for production of isoprene 有权
    使用细胞培养物生产异戊二烯的系统

    公开(公告)号：US09121039B2

    公开(公告)日：2015-09-01

    申请号：US14028342

    申请日：2013-09-16

    Applicant: Danisco US Inc. ,  The Goodyear Tire & Rubber Company

    Inventor： Gopal K. Chotani ,  Joseph C. McAuliffe ,  Caroline M. Peres ,  Gregory M. Whited

    IPC: C12P5/02 ,  C12P5/00

    CPC classification number: C12P5/007 ,  C12P5/026

    Abstract: The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells. The invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity. Additionally, the invention provides methods of producing isoprene by culturing cells under conditions suitable for isoprene production while maintaining cell viability and/or metabolic activity.

    Abstract translation: 本发明的特征在于从培养细胞产生异戊二烯的方法。 本发明还提供包括这些培养细胞的组合物。 本发明提供异戊二烯组合物，例如具有增加的异戊二烯量或增加的纯度的组合物。 另外，本发明提供了通过在适合异戊二烯生产的条件下培养细胞同时维持细胞活力和/或代谢活性来生产异戊二烯的方法。

    COMPOSITION COMPRISING VARIOUS PROTEORHODOPSINS AND/OR BACTERIORHODOPSINS AND USE THEREOF
    3.
    发明申请
    COMPOSITION COMPRISING VARIOUS PROTEORHODOPSINS AND/OR BACTERIORHODOPSINS AND USE THEREOF 审中-公开
    包含各种保护素和/或细菌体的组合物及其用途

    公开(公告)号：US20140085998A1

    公开(公告)日：2014-03-27

    申请号：US13974988

    申请日：2013-08-23

    Applicant: Danisco US Inc.

    Inventor： Richard R. Bott ,  Rasmus B. Jensen ,  Bradley R. Kelemen ,  Donald E. Ward II ,  Gregory M. Whited

    IPC: C09D11/02 ,  G11C7/00 ,  G11B7/242

    CPC classification number: G11C7/00 ,  C07K14/215 ,  C09D11/037 ,  C09D11/50 ,  G11B7/242 ,  Y10S430/146 ,  Y10T428/249921 ,  Y10T428/31623 ,  Y10T428/31685 ,  Y10T428/31725 ,  Y10T428/31783

    Abstract: The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials.

    Abstract translation: 本发明提供了一种固体材料，其包含两种或多种蛋白质视紫红质，两种或更多种细菌视紫红质，或一种或多种细菌视紫红质和一种或多种蛋白质视紫质的固定混合物。 蛋白质视紫红质选自全反式视黄醛的蛋白质视黄素和含视网膜类似物的蛋白质视紫红质; 所有这些都具有不重叠的吸收光谱。 细菌视紫红质选自全反式视网膜含细菌视紫红质和视网膜类似物的细菌视紫红质; 所有这些都具有不重叠的吸收光谱。 本发明还提供一种光学信息载体，例如光学数据存储材料和防欺诈光学数据载体，其包括上述固体材料和选自玻璃，纸，金属，织物材料的基材 和塑料材料，其中所述固体材料沉积在所述基底上。 本发明还提供了包含一种或多种亲水聚合物和各种光致变色材料的混合物的安全油墨。

    POLYMERS OF ISROPENE FROM RENEWABLE RESOURCES
    4.
    发明申请
    POLYMERS OF ISROPENE FROM RENEWABLE RESOURCES 有权
    可再生能源的废弃物聚合物

    公开(公告)号：US20130253141A1

    公开(公告)日：2013-09-26

    申请号：US13792832

    申请日：2013-03-11

    Applicant: THE GOODYEAR TIRE & RUBBER COMPANY ,  DANISCO US INC.

    Inventor： Frank J. Feher ,  Gregory M. Whited ,  Gopal K. Chotani ,  Fernando Valle ,  Carol Fioresi ,  Karl J. Sanford ,  Joseph McAuliffe ,  Marguerite Cervin ,  Aaron S. Puhala ,  Andrei Miasnikov ,  Ilana S. Aldor

    IPC: C08F136/08 ,  C08F236/10 ,  C08F236/08

    CPC classification number: C08F236/18 ,  C08F2/00 ,  C08F36/04 ,  C08F136/08 ,  C08F236/08 ,  C08F236/10 ,  C08F236/12 ,  C08L9/00 ,  C12P5/007 ,  Y10T436/24

    Abstract: It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has δ13C value of greater than −22‰.

    Abstract translation: 已经发现，培养物中的某些细胞可将大于约0.002％的细胞培养基中可用的碳转化为异戊二烯。 这些细胞具有异源核酸，其（i）编码异戊二烯合酶多肽，和（ii）可操作地连接于启动子。 然后可以回收在这种培养基中产生的异戊二烯并聚合成合成橡胶和其它有用的聚合物材料。 本发明的合成含异戊二烯的聚合物提供可证实为从非石化基础资源得到的益处。 它们也可以分析与来自天然来源的橡胶。 本发明更具体地公开了由衍生自异戊二烯单体的重复单元组成的聚异戊二烯聚合物，其中聚异戊二烯聚合物的δ13C值大于-220 / 00。

    Enzymatic Prevention and Control of Biofilm
    7.
    发明申请
    Enzymatic Prevention and Control of Biofilm 审中-公开
    生物膜的酶促预防和控制

    公开(公告)号：US20150118211A1

    公开(公告)日：2015-04-30

    申请号：US14069982

    申请日：2013-11-01

    Applicant: Danisco US Inc.

    Inventor： Christopher C. Barnett ,  Manoj Kumar ,  Gregory M. Whited

    IPC: A01N63/02

    CPC classification number: A01N63/02 ,  C11D3/386 ,  C11D3/38636

    Abstract: The invention provides methods, compositions, and kits for removal of biofilms from surfaces. The methods described herein comprise simultaneous or sequential application of a perhydrolase enzyme and a mixture of other enzymes, such as proteases, glucanases, esterases, mannanases, phospholipases, cellulases, and/or amylases, to a biofilm on a surface, to effect removal of the biofilm.

    Abstract translation: 本发明提供从表面去除生物膜的方法，组合物和试剂盒。 本文描述的方法包括同时或顺序地将表面上的生物膜同时或顺序施用过水解酶和其它酶（例如蛋白酶，葡聚糖酶，酯酶，甘露聚糖酶，磷脂酶，纤维素酶和/或淀粉酶）的混合物，以去除 生物膜。

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