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    MULTIPLE MUTATION VARIANTS OF SERINE PROTEASE
    1.
    发明申请
    MULTIPLE MUTATION VARIANTS OF SERINE PROTEASE 有权
    丝氨酸蛋白酶的多个突变变体

    公开(公告)号：US20140005094A1

    公开(公告)日：2014-01-02

    申请号：US13888300

    申请日：2013-05-06

    Applicant: Danisco US Inc.

    Inventor： Wolfgang Aehle ,  David A. Estell ,  Ronaldus W.J. Hommes ,  Brian E. Jones ,  Marc Kolkman ,  Chris Leeflang ,  Hiroshi Oh ,  Ayrookaran J. Poulose ,  Andrew Shaw ,  Wilhelmus A.H. Van der Kley ,  Leonardus P.M. Van Marrewijk

    IPC: C12N9/52

    CPC classification number: C12N9/52 ,  A23K20/189 ,  A23K50/75 ,  C11D3/386 ,  C12N9/96 ,  C12Y304/21 ,  D06M16/003

    Abstract: The present invention provides novel Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications.

    Abstract translation: 本发明提供了具有多个取代的新型微球菌spp丝氨酸蛋白酶。 特别地，本发明提供了具有多个取代的丝氨酸蛋白酶，编码这些蛋白酶的DNA，包含编码蛋白酶的DNA的载体，用载体DNA转化的宿主细胞和由宿主细胞产生的酶。 本发明还提供了清洁组合物（例如洗涤剂组合物），动物饲料组合物以及包含这些丝氨酸蛋白酶变体的纺织和皮革加工组合物。 在特别优选的实施方案中，本发明提供衍生自本文所述的野生型蛋白酶的突变体（即，变体）蛋白酶。 这些变体蛋白酶也可用于许多应用。

    Compositions and Methods Comprising Alpha-Amylase Variants with Altered Properties
    3.
    发明申请
    Compositions and Methods Comprising Alpha-Amylase Variants with Altered Properties 审中-公开
    包含具有改变性质的α-淀粉酶变体的组合物和方法

    公开(公告)号：US20150087573A1

    公开(公告)日：2015-03-26

    申请号：US14472149

    申请日：2014-08-28

    Applicant: Danisco US Inc.

    Inventor： David A. Estell ,  Brian E. Jones ,  Marc Kolkman ,  Christian D. Adams ,  Edward M. Concar

    IPC: C11D3/386 ,  C12N9/28

    CPC classification number: C11D3/386 ,  C11D3/38681 ,  C12N9/2417 ,  C12N9/54

    Abstract: Described are compositions and methods relating to variant alpha-amylasess having altered biochemical properties and advantageous performance characteristics as compared to a reference alpha-amylase. The variants are suitable for use in various industrial applications such as starch conversion, ethanol production, laundry, dishwashing, pulp and paper production, textile desizing, and/or sweetener production.

    Abstract translation: 描述了与参考α-淀粉酶相比具有改变的生物化学性质和有利的性能特征的变体α-淀粉酶相关的组合物和方法。 这些变体适用于各种工业应用，如淀粉转化，乙醇生产，洗衣，洗碗，纸浆和造纸，纺织品退浆和/或甜味剂生产。

    Multiple mutation variants of serine protease
    4.
    发明授权
    Multiple mutation variants of serine protease 有权
    丝氨酸蛋白酶的多重突变变体

    公开(公告)号：US08865449B2

    公开(公告)日：2014-10-21

    申请号：US13888300

    申请日：2013-05-06

    Applicant: Danisco US Inc.

    Inventor： Wolfgang Aehle ,  David A. Estell ,  Ronaldus W. J. Hommes ,  Brian E. Jones ,  Marc Kolkman ,  Chris Leeflang ,  Hiroshi Oh ,  Ayrookaran J. Poulose ,  Andrew Shaw ,  Wilhelmus A. H. Van der Kley ,  Leonardus P. M. Van Marrewijk

    IPC: C12N9/52 ,  A23K1/165 ,  A23K1/18 ,  C11D3/386 ,  D06M16/00

    CPC classification number: C12N9/52 ,  A23K20/189 ,  A23K50/75 ,  C11D3/386 ,  C12N9/96 ,  C12Y304/21 ,  D06M16/003

    Abstract: The present invention provides novel Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications.

    Abstract translation: 本发明提供了具有多个取代的新型微球菌spp丝氨酸蛋白酶。 特别地，本发明提供了具有多个取代的丝氨酸蛋白酶，编码这些蛋白酶的DNA，包含编码蛋白酶的DNA的载体，用载体DNA转化的宿主细胞和由宿主细胞产生的酶。 本发明还提供了清洁组合物（例如洗涤剂组合物），动物饲料组合物以及包含这些丝氨酸蛋白酶变体的纺织和皮革加工组合物。 在特别优选的实施方案中，本发明提供衍生自本文所述的野生型蛋白酶的突变体（即，变体）蛋白酶。 这些变体蛋白酶也可用于许多应用。

    Multiple Mutation Variants of Serine Protease
    8.
    发明申请
    Multiple Mutation Variants of Serine Protease 审中-公开
    丝氨酸蛋白酶的多重突变变异

    公开(公告)号：US20150072913A1

    公开(公告)日：2015-03-12

    申请号：US14483375

    申请日：2014-09-11

    Applicant: Danisco US Inc.

    Inventor： Wolfgang Aehle ,  David A. Estell ,  Ronaldus W.J. Hommes ,  Brian E. Jones ,  Marc Kolkman ,  Chris Leeflang ,  Hiroshi Oh ,  Ayrookaran J. Poulose ,  Andrew Shaw ,  Wilhelmus A.H. Van der Kley ,  Leonardus P.M. Van Marrewijk

    IPC: C12N9/52 ,  C11D3/386 ,  C12N9/96

    CPC classification number: C12N9/52 ,  A23K20/189 ,  A23K50/75 ,  C11D3/386 ,  C12N9/96 ,  C12Y304/21 ,  D06M16/003

    Abstract: The present invention provides novel Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications.

    Abstract translation: 本发明提供了具有多个取代的新型微球菌spp丝氨酸蛋白酶。 特别地，本发明提供了具有多个取代的丝氨酸蛋白酶，编码这些蛋白酶的DNA，包含编码蛋白酶的DNA的载体，用载体DNA转化的宿主细胞和由宿主细胞产生的酶。 本发明还提供了清洁组合物（例如洗涤剂组合物），动物饲料组合物以及包含这些丝氨酸蛋白酶变体的纺织和皮革加工组合物。 在特别优选的实施方案中，本发明提供衍生自本文所述的野生型蛋白酶的突变体（即，变体）蛋白酶。 这些变体蛋白酶也可用于许多应用。

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