公开(公告)号：US6133472A

公开(公告)日：2000-10-17

申请号：US9110

申请日：1998-01-20

申请人： David Nalewajek ,  David Bradley ,  John Schabel ,  Robert Blomquist

发明人： David Nalewajek ,  David Bradley ,  John Schabel ,  Robert Blomquist

IPC分类号： G02B6/00 ,  C07C43/17 ,  C07C43/172 ,  C07C69/63 ,  C07C309/63 ,  C07C309/73 ,  C08F8/18 ,  C08F16/12 ,  C09D11/02 ,  C09D11/10 ,  C09D129/10 ,  C09J4/00 ,  C09J129/10 ,  G02B6/12 ,  G11B7/2531 ,  G11B7/2533 ,  G11B7/2542 ,  C07C69/00

CPC分类号： C09J129/10 ,  C07C309/73 ,  C07C43/17 ,  C07C43/172 ,  C07C69/63 ,  C08F8/18 ,  C09D11/101 ,  C09D129/10 ,  C09J4/00 ,  G11B7/2531 ,  G11B7/2533 ,  G11B7/2542 ,  G11B7/256

摘要： Fluorine containing oxyvinyl compounds characterized by having one or more oxyvinyl groups separated from fluorine containing groups by at least one alkylene group having 2-8 carbon atoms and by at least one oxygen atom in addition to the oxygen on the oxyvinyl. In general the compounds of the invention have the generic formula:Rz(L).sub.a (Ry).sub.b OROCH.dbd.CH.sub.2.Where L is .dbd.CHCOOROCH.dbd.CH.sub.2 ; a is number of 0 to about 1; R.sub.y is --CO--; b is a number of 0 to about 1; R is cycloalkane or (CH.sub.2).sub.x --, where x is a number of about 2 through about 10; R.sub.z is R.sub.f C.sub.n H.sub.m where R.sub.f is a fluorinated alkylene moiety of about 1 to about 12 carbon atoms which may be linear or branch chained and may contain a further --OROCH.dbd.CH.sub.2 group; n is an integer of about 1 through about 6; and m is an integer of n to 2n. The compounds are suitable for use in optical devices such as fibers and waveguides, are readily radiation curable and curable by other means, and can be formulated to be of low viscosity when applied. The compounds are also suited for coatings, inks and adhesive and other applications. The invention includes methods for preparing and using the compounds and products employing the compounds. Intermediates to prepare the compounds and methods to prepare the intermediates are also included.

摘要翻译： 含氟氧基乙烯基化合物的特征在于具有一个或多个氧基乙烯基，其含氟基团通过至少一个具有2-8个碳原子的亚烷基和至少一个氧原子与氧基乙烯基上的氧分开。 通常，本发明的化合物具有以下通式：Rz（L）a（Ry）bOROCH = CH 2。其中L = CHCOOROCH = CH 2; a是0到1的数字; Ry是-CO-; b是0到1的数; R是环烷烃或（CH 2）x - ，其中x是约2至约10的数; Rz是RfCnHm，其中Rf是约1至约12个碳原子的氟化亚烷基部分，其可以是直链或支链，并且可以含有另外的-OROCH = CH 2基团; n为约1至约6的整数; m为n〜2n的整数。 该化合物适用于诸如纤维和波导的光学装置，易于辐射固化并且可通过其它方法固化，并且可以在施用时配制成具有低粘度。 这些化合物也适用于涂料，油墨和粘合剂等应用。 本发明包括制备和使用化合物和使用该化合物的产品的方法。 还包括制备化合物的中间体和制备中间体的方法。

公开(公告)号：US20070118003A1

公开(公告)日：2007-05-24

申请号：US11284379

申请日：2005-11-21

申请人： David Bradley ,  David Nalewajek ,  Robert Bell

发明人： David Bradley ,  David Nalewajek ,  Robert Bell

IPC分类号： C07C19/08

CPC分类号： C07C17/206 ,  C07C17/21 ,  C07C19/08

摘要： A process for the production of C2-C4 hydrofluorocarbon, such as 1,1,1,3,3-pentafluoropropane, by contacting a non-fluorinated hydrochlorocarbon with a fluorinating agent, such as hydrogen fluoride, in a liquid catalyst system preferably comprising fluorinated superacid catalyst prepared from SbF5, NbF5, TaF5 or TaF5/SnF4 and HF.

摘要翻译： 通过使非氟化氢氯烃与氟化氢如氟化氢接触，在液体催化剂体系中将C2-C4氢氟烃如1,1,1,3,3-五氟丙烷生产的方法优选包括含氟化合物 由SbF 5，NbF 5，TaF 5或TaF 5 / SnF 4制备的超强酸催化剂， 和/或HF。

公开(公告)号：US20050113606A1

公开(公告)日：2005-05-26

申请号：US10718475

申请日：2003-11-20

申请人： Robert Bell ,  Timothy Demmin ,  David Bradley ,  David Nalewajek

发明人： Robert Bell ,  Timothy Demmin ,  David Bradley ,  David Nalewajek

IPC分类号： C07C51/21 ,  C07C51/58

CPC分类号： C07C51/58 ,  C07C53/48

摘要： The invention pertains to a process for preparing chlorodifluoroacetyl fluoride (CDAF) by oxidation of chlorotrifluoroethylene (CTFE) in a solvent using a continuously stirred tank reactor. It provides a process for the production of chlorodifluoroacetyl fluoride by comprises reacting a solvent solution of chlorotrifluoroethylene with oxygen in a reactor to form a product which comprises chlorodifluoroacetyl fluoride. The reacting may be conducted in a continuous or batch mode.

摘要翻译： 本发明涉及通过使用连续搅拌釜式反应器在溶剂中氧化三氟氯乙烯（CTFE）来制备氯二氟乙酰氟（CDAF）的方法。 它提供了一种生产氯二氟乙酰氟的方法，包括在反应器中使氯三氟乙烯的溶剂溶液与氧反应形成包含氯二氟乙酰氟的产物。 反应可以以连续或间歇的方式进行。

公开(公告)号：US06800788B2

公开(公告)日：2004-10-05

申请号：US10173915

申请日：2002-06-18

申请人： David Bradley ,  Jing Ji Ma ,  Haridasan K. Nair ,  David Nalewajek ,  Leonard M. Stachura ,  George Samuels ,  Michael Van Der Puy

发明人： David Bradley ,  Jing Ji Ma ,  Haridasan K. Nair ,  David Nalewajek ,  Leonard M. Stachura ,  George Samuels ,  Michael Van Der Puy

IPC分类号： C07C2318

CPC分类号： D06M15/21 ,  C07C69/653 ,  C07C233/20 ,  C08F20/22 ,  C08F20/28 ,  D06M15/277 ,  D06M2200/12

摘要： Provided are fluorine-containing compounds, and polymers derived therefrom, for use in compositions used for treating textile substrates. Also provided are methods of making fluorine-containing compounds and polymers derived therefrom, compositions comprising the compounds and/or polymers of the present invention, methods of treating substrates, and the treated products derived therefrom.

摘要翻译： 提供含氟化合物及其衍生的聚合物，用于处理织物基材的组合物中。 还提供了制备含氟化合物和由其衍生的聚合物的方法，包含本发明的化合物和/或聚合物的组合物，处理底物的方法和由其衍生的处理产物。

公开(公告)号：US09442540B2

公开(公告)日：2016-09-13

申请号：US12634441

申请日：2009-12-09

申请人： Tung M. Nguyen ,  Richard Au ,  David Nguyen ,  Tipatat Chennavasin ,  Najaf Rizvi ,  David Bradley ,  Matthew Humphreys

发明人： Tung M. Nguyen ,  Richard Au ,  David Nguyen ,  Tipatat Chennavasin ,  Najaf Rizvi ,  David Bradley ,  Matthew Humphreys

IPC分类号： G06F13/00 ,  H05K7/10 ,  G06F1/20 ,  H05K5/00 ,  H05K7/20 ,  G06F1/26 ,  G06F1/18

CPC分类号： G06F9/44505 ,  G06F1/181 ,  G06F1/189 ,  G06F1/20 ,  G06F1/26 ,  G06F13/4068 ,  Y02D10/14 ,  Y02D10/151

摘要： A multi-node computer system, comprising: a plurality of nodes, a system control unit and a carrier board. Each node of the plurality of nodes comprises a processor and a memory. The system control unit is responsible for: power management, cooling, workload provisioning, native storage servicing, and I/O. The carrier board comprises a system fabric and a plurality of electrical connections. The electrical connections provide the plurality of nodes with power, management controls, system connectivity between the system control unit and the plurality of nodes, and an external network connection to a user infrastructure. The system control unit and the carrier board provide integrated, shared resources for the plurality of nodes. The multi-node computer system is provided in a single enclosure.

摘要翻译： 一种多节点计算机系统，包括：多个节点，系统控制单元和载板。 多个节点中的每个节点包括处理器和存储器。 系统控制单元负责：电源管理，冷却，工作负载配置，本机存储服务和I / O。 承载板包括系统结构和多个电连接。 电连接为多个节点提供功率，管理控制，系统控制单元和多个节点之间的系统连接以及到用户基础设施的外部网络连接。 系统控制单元和载板为多个节点提供集成的共享资源。 多节点计算机系统提供在单个机箱中。

公开(公告)号：US20090024713A1

公开(公告)日：2009-01-22

申请号：US11779544

申请日：2007-07-18

申请人： James Strasenburgh ,  David Bradley

发明人： James Strasenburgh ,  David Bradley

IPC分类号： G06F15/173

CPC分类号： G06F9/4856 ,  H04L41/06 ,  H04L41/16 ,  H04L41/5041 ,  H04L41/5054

摘要： A method is used with a data center that includes services that are interdependent. The method includes experiencing an event in the data center and, in response to the event, using a rules-based expert system to determine a sequence in which the services are to be moved, where the sequence is based on dependencies of the services, and moving the services from first locations to second locations in accordance with the sequence.

摘要翻译： 与包含相互依赖的服务的数据中心一起使用的方法。 该方法包括在数据中心中遇到事件，并且响应于该事件，使用基于规则的专家系统来确定要在其中移动服务的序列，其中序列基于服务的依赖性，以及 根据顺序将服务从第一个位置移动到第二个位置。

公开(公告)号：US07457693B2

公开(公告)日：2008-11-25

申请号：US11033051

申请日：2005-01-10

申请人： John Olsen ,  David Bradley ,  Rhesa Jenkins

发明人： John Olsen ,  David Bradley ,  Rhesa Jenkins

IPC分类号： G01M17/00

CPC分类号： G06K19/07758 ,  B60R25/1004 ,  B60R25/102 ,  B60R25/33 ,  B60R2325/101 ,  B60R2325/105 ,  G06K2017/0096 ,  G06Q10/08 ,  G07C5/008 ,  G07C5/085 ,  G08B21/0261 ,  G08B21/0275 ,  G08G1/042 ,  G08G1/202

摘要： The invention is directed to a data collection and evaluation system that includes a telematics device for collecting, time-stamping, and storing vehicle sensor data. Examples of the type of data collected include door data, ignition data, speed data, global positioning data, and diagnostic and trouble code data. The system further includes an external data acquisition device, such as a mainframe computer system or a hand-held computing device like an iPAQ. The external data acquisition device is configured to communicate with the telematics device over a wireless network, which enables the telematics device to transmit the time-stamped data to the external data acquisition device and receive information and instructions from the external data acquisition device. The ability of the system to automatically collect and transfer data and communicate with an external data acquisition device allows for the automation of fleet management processes, vehicle maintenance and repair processes, and certain security features.

摘要翻译： 本发明涉及一种数据收集和评估系统，其包括用于收集，时间戳和存储车辆传感器数据的远程信息处理设备。 收集的数据类型的示例包括门数据，点火数据，速度数据，全球定位数据以及诊断和故障代码数据。 该系统还包括诸如主机计算机系统或诸如iPAQ的手持式计算设备的外部数据采集设备。 外部数据采集设备被配置为通过无线网络与远程信息处理设备进行通信，这使远程信息处理设备能够将时间戳数据发送到外部数据采集设备，并从外部数据采集设备接收信息和指令。 系统自动收集和传输数据并与外部数据采集设备进行通信的能力允许车队管理过程的自动化，车辆维护和维修过程以及某些安全功能。

公开(公告)号：US20060187041A1

公开(公告)日：2006-08-24

申请号：US11054709

申请日：2005-02-09

申请人： John Olsen ,  David Bradley

发明人： John Olsen ,  David Bradley

IPC分类号： G08B13/14 ,  H04Q5/22 ,  G06F7/00 ,  G06K7/00

CPC分类号： B65B11/045

摘要： The invention involves reading RFID transponders affixed to items by rotating the items as they are exposed to an RFID reader as may be incorporated in a normal processing, manufacturing or shipping process such as wrapping items in a protective membrane using a system that includes a commercially-available pallet wrapper adapted to be controlled by computer, and with an RFID transponder reading device mounted to the carriage device of the pallet wrapper. The computer interfaces with a programmable logic controller that controls the pallet wrapper and the RFID reader. The computer causes a predetermined number of wraps of the shipping membrane to be wrapped around a portion of items and the pallet to secure the items to the pallet. The RFID tags on the items on the pallet are read as the items rotate near the fixed RFID reader that is mounted to a carriage holding the shipping membrane.

摘要翻译： 本发明涉及通过在物品暴露于RFID读取器时旋转物品来阅读固定在物品上的RFID应答器，这可以包括在通常的处理，制造或运输过程中，例如使用包括商业上可接受的系统的系统在保护膜中包裹物品， 适用于由计算机控制的可用托盘包装件，以及安装在托盘包装纸托架装置上的RFID应答器读取装置。 计算机与可编程逻辑控制器接口，可控制托盘包装纸和RFID阅读器。 计算机使预定数量的运送膜包裹在一部分物品和托盘上以将物品固定到托盘上。 随着物品在固定RFID读取器附近旋转，物品上的RFID标签被读取，该RFID读取器安装在支撑运送膜的支架上。

公开(公告)号：US20050252596A1

公开(公告)日：2005-11-17

申请号：US10847184

申请日：2004-05-17

申请人： John Olsen ,  David Bradley ,  Rhesa Jenkins

发明人： John Olsen ,  David Bradley ,  Rhesa Jenkins

IPC分类号： B07C7/00 ,  B32B31/00

CPC分类号： B07C7/005

摘要： The present invention provides novel systems and methods for processing packages through a delivery network using a hub assist label. Generally described, the hub assist label includes indicia of a sequence of sorting locations that designates the flow of a package through a delivery network.

摘要翻译： 本发明提供了使用轮毂辅助标签通过输送网络处理包装的新型系统和方法。 通常描述，轮毂辅助标签包括指定通过输送网络的包装流动的排序位置序列的标记。

公开(公告)号：US20210069314A1

公开(公告)日：2021-03-11

申请号：US16896060

申请日：2020-06-08

申请人： David S. Terman ,  David Bradley

发明人： David S. Terman ,  David Bradley

IPC分类号： A61K39/085 ,  A61P35/00

摘要： Amid their enormous biologic diversity, we have discovered a new group of evolutionarily modified SAgs, SEG-SEI, that in partnership with endogenous SEG-SEI retain the ability to generate anti-tumor T effector cell devoid of the cytokine-mediated toxicity. Such toxicity has hampered the effective use of canonical SAgs for human cancer treatment. For their MHCII partner, we selected the human HLA-DQ8 allele and show that its contact with SEG-SEI is obligatory for the anti-tumor effect. Here we further show that SEG-SEI collaborate with HLA-DQ8 alleles to expand, differentiate, and chemotactically recruit a tumor neoantigen-primed tumor reactive T cell population that propagates both an acute tumoricidal response and long-term T-cell memory/survival.