摘要:
This document relates to molecularly imprinted polymers for use in mammals. For example, methods and materials for capturing a molecule in the body of a mammal using a molecularly imprinted polymer are provided. In some cases methods for delivering a molecule using a molecularly imprinted polymer into the body of a mammal are provided. The methods provided can be used to target any molecule in the body of a mammal.
摘要:
A medical device is provided having a needle or a catheter, insertable into a living body, which defines a plurality of holes in fluid communication with a central lumen. The holes may be of various patterns located and angled to create a desired injectate cloud pattern when an injectate is forced through the central lumen and through the plurality of holes. One embodiment provides various designs including a moveable sheath or stylet used to selectively occlude one or more of the holes while in use, thereby providing an operating physician a way to manipulate the cloud pattern anytime during the introduction of the injectate. A reducer may be used in conjunction with these needles which provides an increased degree of control when injecting very small quantities of fluid.
摘要:
An apparatus for use as a catheter, a guidewire, a catheter sheath for use with catheter introducers or a drug infusion catheter/guidewire. The apparatus includes a flexible tubular member with an encasing covering the tubular member that creates a fluid-tight seal around the periphery of the tubular member. The tubular member is self-supporting and includes a plurality of apertures therein in a predetermined configuration to increase the flexibility of the tubular member.
摘要:
An asymmetric membrane formed from a sulphonated polyarylethersulphone has a salt rejection of at least 99%. Alternatively, a membrane has a good salt rejection and an acceptable water flux such that the ratio ##EQU1## has the value of at least 0.7. The membranes can be obtained using barium salts of the sulphonated polyarylethersulphone, with the proportion of barium being controlled to be at least 85%, preferably at least 86%, and not more than 91%, preferably not more than 90% of the barium required to react with the sulphonic acid groups on the sulphonated polymer.
摘要:
A medical monitoring apparatus designed to be implanted in the vascular system is capable of sensing and transmitting via a telemetry link to an external monitor both pressure and temperature information. An internally or externally powered microcircuit component is supported on a stent-like structure and adapted to be placed in the vascular system. Placement in the ventricular septum permits measurement of pressure and temperature in the left ventricle without introducing thrombus generating materials in the left ventricle.
摘要:
Use of pregnancy-associated plasma protein-A as a marker for inflammatory conditions, and in particular, for acute coronary syndromes is described.
摘要:
Methods and devices for percutaneous, in situ coronary bypass wherein a tissue puncturing catheter is used to form blood flow paths between an artery and an adjacent vein such that arterial blood will flow through a segment of the adjacent vein, thereby bypassing a lesion in the artery. The tissue puncturing catheter comprises a flexible catheter having a tissue puncturing apparatus such as a sharp tipped member, an electro-surgical apparatus or a laser beam passable therefrom to create the desired blood flow paths between the artery and vein. Stents are provided for facilitating blood flow through the blood flow paths and the segment of the vein used as the bypass conduit. One such stent is specially constructed to carry arterial blood in one direction through the vein segment while allowing venous blood to continue to flow in the opposite direction through that venous segment.
摘要:
A steerable catheter in which a guidewire can serve a dual purpose of deflecting a bendable element at a distal end of the steerable catheter and as a guidewire to facilitate the placement of a working catheter within the vascular system. The guidewire is adapted to be slidingly received within routing eyelets or the like where one of such eyelets is disposed at a distal end of the bendable element and another near the proximal end thereof. The guidewire can be readily advanced in the distal direction relative to the steerable catheter, but tensioning of the guidewire at its proximal end serves to deflect and bend the bendable element.
摘要:
A polymer solution contains a sulphonated polyarylethersulphone in a solvent mixture containing at least three components, where the solvent mixture has a delta-H in the range from 3 to 8.5; a delta-P in the range from 4 to 8 and a delta-D in the range 7.2 to 9.5 and each component of the solvent mixture is a liquid or low melting solid which is a non-solvent or poor solvent for the sulphonated polyarylethersulphone, and at least one of the components satisfies at least one of the conditions:a) said component has a delta-D of less than 8 when the value of delta-P is not more than 3; andb) said component has a delta-H of greater than 3 when the value of delta-P is at least 8.5; andc) said component has a delta-H of less than 8 when it contains at least one hydroxylic group; andd) said component is free of hydroxylic groups and has a delta-P which is greater than 3 and less than 8.5.The solution can be used for the production of membranes suitable for use in reverse osmosis applications.
摘要:
Use of pregnancy-associated plasma protein-A as a marker for inflammatory conditions, and in particular, for acute coronary syndromes is described.