Detection conjugate and method for analysis
    3.
    发明授权
    Detection conjugate and method for analysis 有权
    检测共轭和分析方法

    公开(公告)号:US08865414B2

    公开(公告)日:2014-10-21

    申请号:US13139870

    申请日:2009-12-17

    CPC分类号: C12Q1/6804 C12Q2565/101

    摘要: The invention provides a combination of reagents as a test kit containing a detection conjugate having a binding portion and a reagent for deactivating of the fluorochrome portion by interaction with the linker. The binding portion especially is an antibody portion. The detection conjugate has a fluorochrome portion connected to the antibody portion, and a linker connected to the fluorochrome portion, wherein the linker comprises an oligonucleotide. The fluorochrome portion can be deactivated by hydrolysis of the linker or by specific hybridization of a quencher having an oligonucleotide to the linker.

    摘要翻译: 本发明提供试剂的组合作为测试试剂盒,其含有具有结合部分的检测缀合物和通过与接头相互作用而使荧光染料部分失活的试剂。 结合部分特别是抗体部分。 检测缀合物具有连接到抗体部分的荧光染料部分和与荧光染料部分连接的连接体,其中连接体包含寡核苷酸。 可以通过接头的水解或通过具有寡核苷酸的猝灭剂与接头的特异性杂交来使荧光染料部分失活。

    DEVICE AND METHOD FOR ANALYSING CELLS
    4.
    发明申请
    DEVICE AND METHOD FOR ANALYSING CELLS 审中-公开
    用于分析细胞的装置和方法

    公开(公告)号:US20120129193A1

    公开(公告)日:2012-05-24

    申请号:US13126116

    申请日:2009-10-27

    IPC分类号: G01N21/64 C12M1/34

    CPC分类号: G01N33/5005 B01L3/5027

    摘要: There is provided a carrier substrate for nonspecific immobilization of living bacterial and/or eukaryotic cells, especially of animal cells, which can be present as single cells, cell agglomerates or tissue sections. The surface of the carrier substrate is provided at least sectionally with a layer having or consisting of oligonucleic acids, preferably having ribonucleic acids covalently coupled to the carrier substrate, e.g. RNA, preferably single-stranded or double-stranded DNA.

    摘要翻译: 提供了用于非特异性固定生物细菌和/或真核细胞,特别是动物细胞的载体底物,其可以作为单细胞,细胞聚集体或组织切片存在。 载体衬底的表面至少部分地设置有具有或由低聚核酸组成的层,优选具有共价偶联到载体衬底的核糖核酸,例如, RNA,优选单链或双链DNA。

    SEMI-CONDUCTOR SUBSTRATE AND METHOD OF MASKING LAYER FOR PRODUCING A FREE-STANDING SEMI-CONDUCTOR SUBSTRATE BY MEANS OF HYDRIDE-GAS PHASE EPITAXY
    5.
    发明申请
    SEMI-CONDUCTOR SUBSTRATE AND METHOD OF MASKING LAYER FOR PRODUCING A FREE-STANDING SEMI-CONDUCTOR SUBSTRATE BY MEANS OF HYDRIDE-GAS PHASE EPITAXY 有权
    半导体基板和用于通过氢化气相外延生产自由稳定的半导体基板的掩膜层的方法

    公开(公告)号:US20100096727A1

    公开(公告)日:2010-04-22

    申请号:US11996446

    申请日:2006-08-24

    摘要: The invention relates to a free-standing semiconductor substrate as well as a process and a mask layer for the manufacture of a free-standing semiconductor substrate, wherein the semiconductor substrate self-separates from the starting substrate without further process steps.The process according to the invention for the manufacture of a semiconductor substrate comprises the following process steps: providing a starting substrate, forming a mask layer with a multitude of openings on the starting substrate, growing at least one semiconductor substrate, wherein the mask layer is laterally overgrown by at least one semiconductor material, and subsequent, cooling of starting substrate, mask layer and semiconductor substrate, wherein the material for forming the mask layer consists at least partially of tungsten silicide nitride or tungsten silicide, and wherein the semiconductor substrate and the starting substrate are caused to separate during the growth of the at least one semiconductor substrate or during cooling, and wherein a semiconductor substrate is obtained free-standing. The mask layer according to the invention for the manufacture of a free-standing semiconductor substrate here consists at least partially of tungsten silicide nitride or tungsten silicide.

    摘要翻译: 本发明涉及独立式半导体衬底以及用于制造独立式半导体衬底的工艺和掩模层,其中半导体衬底与起始衬底自分离而无需进一步的工艺步骤。 根据本发明的用于制造半导体衬底的方法包括以下工艺步骤:提供起始衬底,在起始衬底上形成具有多个开口的掩模层,生长至少一个半导体衬底,其中掩模层是 由至少一种半导体材料横向长满,以及随后冷却起始衬底,掩模层和半导体衬底,其中用于形成掩模层的材料至少部分由硅化钨或硅化钨组成,并且其中半导体衬底和 使起始衬底在至少一个半导体衬底的生长期间或在冷却期间分离,并且其中独立地获得半导体衬底。 本发明的用于制造独立式半导体衬底的掩模层至少部分地由硅化钨或氮化硅构成。

    DETECTION CONJUGATE AND METHOD FOR ANALYSIS
    7.
    发明申请
    DETECTION CONJUGATE AND METHOD FOR ANALYSIS 有权
    检测结合和分析方法

    公开(公告)号:US20110311966A1

    公开(公告)日:2011-12-22

    申请号:US13139870

    申请日:2009-12-17

    IPC分类号: G01N21/64 C12Q1/68

    CPC分类号: C12Q1/6804 C12Q2565/101

    摘要: The invention provides a combination of reagents as a test kit containing a detection conjugate having a binding portion and a reagent for deactivating of the fluorochrome portion by interaction with the linker. The binding portion especially is an antibody portion. The detection conjugate has a fluorochrome portion connected to the antibody portion, and a linker connected to the fluorochrome portion, wherein the linker comprises an oligonucleotide. The fluorochrome portion can be deactivated by hydrolysis of the linker or by specific hybridization of a quencher having an oligonucleotide to the linker.

    摘要翻译: 本发明提供试剂的组合作为测试试剂盒,其含有具有结合部分的检测缀合物和通过与接头相互作用而使荧光染料部分失活的试剂。 结合部分特别是抗体部分。 检测缀合物具有连接到抗体部分的荧光染料部分和与荧光染料部分连接的连接体,其中连接体包含寡核苷酸。 可以通过接头的水解或通过具有寡核苷酸的猝灭剂与接头的特异性杂交来使荧光染料部分失活。