专利检索 ap:("Douglas Hutchinson" OR "John Bellettini" OR "David Betebenner" OR "Richard Bishop" OR "Thomas Borchardt" OR "Todd Bosse" OR "Russell Cink" OR "Charles Flentge" OR "Bradley Gates" OR "Brian Green" OR "Mira Hinman" OR "Peggy Huang" OR "Larry Klein" OR "Allan Krueger" OR "Daniel Larson" OR "M. Leanna" OR "Dachun Liu" OR "Darold Madigan" OR "Keith McDaniel" OR "John Randolph" OR "Todd Rockway" OR "Teresa Rosenberg" OR "Kent Stewart" OR "Vincent Stoll" OR "Rolf Wagner" OR "Ming Yeung") AND inv:"Charles Flentge" 第 1 页

1.

发明申请
Anti-infective agents 失效
标题翻译：抗感染剂

公开(公告)号：US20050107364A1

公开(公告)日：2005-05-19

申请号：US10925072

申请日：2004-08-24

申请人： Douglas Hutchinson , John Bellettini , David Betebenner , Richard Bishop , Thomas Borchardt , Todd Bosse , Russell Cink , Charles Flentge , Bradley Gates , Brian Green , Mira Hinman , Peggy Huang , Larry Klein , Allan Krueger , Daniel Larson , M. Leanna , Dachun Liu , Darold Madigan , Keith McDaniel , John Randolph , Todd Rockway , Teresa Rosenberg , Kent Stewart , Vincent Stoll , Rolf Wagner , Ming Yeung

发明人： Douglas Hutchinson , John Bellettini , David Betebenner , Richard Bishop , Thomas Borchardt , Todd Bosse , Russell Cink , Charles Flentge , Bradley Gates , Brian Green , Mira Hinman , Peggy Huang , Larry Klein , Allan Krueger , Daniel Larson , M. Leanna , Dachun Liu , Darold Madigan , Keith McDaniel , John Randolph , Todd Rockway , Teresa Rosenberg , Kent Stewart , Vincent Stoll , Rolf Wagner , Ming Yeung

IPC分类号： A61K31/549 , C07D285/26

CPC分类号： C07D207/08 , C07C323/22 , C07C323/56 , C07C323/60 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2602/10 , C07D263/14 , C07D285/24 , C07D417/06 , C07D417/08 , C07D417/12 , C07D513/04 , C07F9/6547

摘要： Compounds having the formula are hepatitis C (HCV) polymerase inhibitors. Also disclosed are a composition and method for inhibiting hepatitis C (HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.

摘要翻译： 具有下式的化合物是丙型肝炎（HCV）聚合酶抑制剂。还公开了用于抑制丙型肝炎（HCV）聚合酶，制备该化合物的方法和该方法中使用的合成中间体的组合物和方法。

2.

发明申请
HIV protease inhibiting compounds 审中-公开
标题翻译： HIV蛋白酶抑制化合物

公开(公告)号：US20050131042A1

公开(公告)日：2005-06-16

申请号：US10733915

申请日：2003-12-11

申请人： Charles Flentge , Hui-Ju Chen , David DeGoey , William Flosi , David Grampovnik , Peggy Huang , Dale Kempf , Larry Klein , Allan Krueger , Darold Madigan , John Randolph , Minghua Sun , Ming Yeung , Chen Zhao

发明人： Charles Flentge , Hui-Ju Chen , David DeGoey , William Flosi , David Grampovnik , Peggy Huang , Dale Kempf , Larry Klein , Allan Krueger , Darold Madigan , John Randolph , Minghua Sun , Ming Yeung , Chen Zhao

IPC分类号： A61K31/175 , A61K31/18 , A61K31/195 , A61K31/277 , A61K31/4168 , A61K31/65 , A61K45/06 , C07C311/17 , C07D213/30 , C07D213/40 , C07D213/78 , C07D233/32 , C07D233/72 , C07D277/28 , C07D277/46 , C07D277/48 , C07D307/20 , C07D307/42 , C07D401/06 , C07D403/06 , C07D403/10 , C07D405/06 , C07D405/10 , C07D409/06 , C07D417/06 , C07D417/14 , C07D471/04 , C07D493/04

CPC分类号： C07D471/04 , A61K31/175 , A61K31/18 , A61K31/195 , A61K31/277 , A61K31/4168 , A61K31/65 , A61K45/06 , C07D213/30 , C07D213/40 , C07D213/78 , C07D233/32 , C07D233/72 , C07D277/28 , C07D277/46 , C07D277/48 , C07D307/20 , C07D307/42 , C07D401/06 , C07D403/06 , C07D403/10 , C07D405/06 , C07D405/10 , C07D409/06 , C07D417/06 , C07D417/14 , C07D493/04 , A61K2300/00

摘要： A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

摘要翻译： 公开了式的化合物作为HIV蛋白酶抑制剂。还公开了用于抑制HIV感染的方法和组合物。

3.

发明申请
Anti-infective agents 有权

公开(公告)号：US20060287300A1

公开(公告)日：2006-12-21

申请号：US11363377

申请日：2006-02-27

申请人： Larry Klein , Peggy Huang , John Randolph , Douglas Hutchinson , Ming Yeung , Charles Flentge

发明人： Larry Klein , Peggy Huang , John Randolph , Douglas Hutchinson , Ming Yeung , Charles Flentge

IPC分类号： A61K31/549 , C07D285/22

CPC分类号： C07D471/04 , C07D285/24 , C07D285/30 , C07D417/12

摘要： Compounds having the formula are hepatitis C (HCV) polymerase inhibitors. Also disclosed are compositions and methods for inhibiting hepatitis C (HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.

4.

发明申请
HIV protease inhibiting compounds 有权

公开(公告)号：US20050159469A1

公开(公告)日：2005-07-21

申请号：US11010177

申请日：2004-12-10

申请人： John Randolph , Hui-Ju Chen , David DeGoey , Charles Flentge , William Flosi , David Grampovnik , Peggy Huang , Douglas Hutchinson , Dale Kempf , Larry Klein , Ming Yeung

发明人： John Randolph , Hui-Ju Chen , David DeGoey , Charles Flentge , William Flosi , David Grampovnik , Peggy Huang , Douglas Hutchinson , Dale Kempf , Larry Klein , Ming Yeung

IPC分类号： A61K31/4166 , A61K31/4178 , C07C243/24 , C07C271/22 , C07D401/06 , C07D401/14 , C07D403/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/06 , C07D417/14 , C07D43/02

CPC分类号： C07C271/22 , C07D401/06 , C07D401/14 , C07D403/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/06 , C07D417/14

摘要： A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

5.

发明申请
Novel compounds that are useful for improving pharmacokinetics 有权
标题翻译：可用于改善药代动力学的新型化合物

公开(公告)号：US20060199851A1

公开(公告)日：2006-09-07

申请号：US11366172

申请日：2006-03-02

申请人： Dale Kempf , Charles Flentge , John Randolph , Peggy Huang , Larry Klein

发明人： Dale Kempf , Charles Flentge , John Randolph , Peggy Huang , Larry Klein

IPC分类号： A61K31/427 , A61K31/426 , C07D417/02 , C07D277/38

CPC分类号： C07D277/30 , A61K31/426 , A61K31/427 , A61K45/06 , C07C53/18 , C07D213/30 , C07D231/12 , C07D233/64 , C07D263/32 , C07D277/24 , C07D277/38 , C07D277/587 , C07D333/16 , C07D417/04

摘要： Novel compounds of formula 1 or a pharmaceutically acceptable salt thereof inhibit cytochrome P450 monooxygenase.

摘要翻译： 新的式1化合物或其药学上可接受的盐抑制细胞色素P450单加氧酶。