Aromatic phosphonium salts and their use as labeling reagents in mass spectrometry analysis
    2.
    发明申请
    Aromatic phosphonium salts and their use as labeling reagents in mass spectrometry analysis 审中-公开
    芳族鏻盐及其在质谱分析中用作标记试剂

    公开(公告)号:US20070087446A1

    公开(公告)日:2007-04-19

    申请号:US10553307

    申请日:2004-04-14

    IPC分类号: G01N24/00

    摘要: This invention relates to methods and reagents for the assay, detection, quantification, location, or analysis of each of a plurality of substances of interest (“analytes”) in a sample in which each substance is labeled with a cationic triarylphosphonium group. The present invention also provides MALDI mass spectrometry techniques in which the analysis of samples containing low molecule weight analytes is not obscured by matrix components. The invention also provides labeling reagents for use in labeling analytes prior to MS analysis in which the labeled analytes have a molecular weight above the useful detection threshold of MALDI techniques. In some aspects, the invention provides methods of quantitative MS analysis of components of a sample. Methods of the present invention include sensitive techniques for desorption/ionization of molecules at the picomole, femtomole, and attomole amounts. Another benefit of the present invention is that measurement of m/Z values is not complicated by the low-mass interference that a matrix normally offers, and therefore the invention provides methods of MALDI MS analysis of low molecular weight samples as well as mixtures of high and low molecular weight samples.

    摘要翻译: 本发明涉及用于将每种物质用阳离子三芳基鏻基团标记的样品中的多种感兴趣物质(“分析物”)中的每一种的测定,检测,定量,定位或分析的方法和试剂。 本发明还提供MALDI质谱技术,其中含有低分子量分析物的样品的分析不被基质组分遮蔽。 本发明还提供用于在MS分析之前标记分析物的标记试剂,其中标记的分析物的分子量高于MALDI技术的有用检测阈值。 在一些方面,本发明提供了样品组分的定量MS分析方法。 本发明的方法包括用于在皮摩尔,飞甲和阿托莫尔量下解吸/电离分子的敏感技术。 本发明的另一个好处是,通过基质通常提供的低质量干扰,m / Z值的测量并不复杂,因此本发明提供了低分子量样品的MALDI MS分析方法以及高分子量混合物 和低分子量样品。

    Destructible surfactants and uses thereof
    3.
    发明申请
    Destructible surfactants and uses thereof 审中-公开
    可破坏的表面活性剂及其用途

    公开(公告)号:US20080027234A1

    公开(公告)日:2008-01-31

    申请号:US11811696

    申请日:2007-06-11

    IPC分类号: C07D319/06 C07D317/14

    摘要: Destructible surfactants and methods of using same are provided. The invention includes anionic surfactants having a dioxolane or dioxane functional group which enables the surfactant to be broken down under acidic conditions. The invention also includes methods of making anionic surfactants and methods of using anionic surfactants in a variety of applications.

    摘要翻译: 提供了可破坏的表面活性剂及其使用方法。 本发明包括具有二氧戊环或二恶烷官能团的阴离子表面活性剂,其使表面活性剂在酸性条件下分解。 本发明还包括制备阴离子表面活性剂的方法和在各种应用中使用阴离子表面活性剂的方法。

    Enterprise level business information networking for changes in a database
    6.
    发明授权
    Enterprise level business information networking for changes in a database 有权
    企业级业务信息网络,用于更改数据库

    公开(公告)号:US08478722B2

    公开(公告)日:2013-07-02

    申请号:US12945410

    申请日:2010-11-12

    IPC分类号: G06F7/00 G06F17/00

    摘要: Systems, apparatus, and methods for implementing enterprise level social and business information networking are provided. Users can receive relevant information about a database system and its users at an appropriate time. Users can then use this relevant information to reduce errors and limit redundant efforts. For example, an update of a record in the database can be identified, and a story created automatically about the update and sent to the users that are following the record. Which updates have stories created and which stories are to be sent to which users can be configured. Other events besides updating of records can also be tracked. For example, actions of a user that result in an event can be tracked, where such tracking can also be configurable. Subscriptions to follow an object can be automatic, and access checks can be used to ensure that unauthorized users do not see certain data.

    摘要翻译: 提供了实施企业级社会和商业信息网络的系统,设备和方法。 用户可以在适当的时间接收有关数据库系统及其用户的相关信息。 然后,用户可以使用此相关信息来减少错误并限制冗余工作。 例如,可以识别数据库中记录的更新,并自动创建关于更新的故事,并将其发送给跟随记录的用户。 哪些更新创建了故事,哪些故事要发送给哪些用户可以配置。 还可以跟踪除记录更新之外的其他事件。 例如,可以跟踪导致事件的用户的动作,这样的跟踪也可以被配置。 可以自动跟踪对象的订阅,并且可以使用访问检查来确保未经授权的用户看不到某些数据。

    Simulation method for transistor unsuitable for existing model
    7.
    发明授权
    Simulation method for transistor unsuitable for existing model 有权
    晶体管的仿真方法不适合现有的模型

    公开(公告)号:US08285524B2

    公开(公告)日:2012-10-09

    申请号:US12608551

    申请日:2009-10-29

    IPC分类号: G06F17/50

    CPC分类号: G06F17/5036

    摘要: A simulation method includes determining a relationship between stress time and a degradation rate of drain current on a basis of a table in which data of a lifetime of a transistor, or the degradation rate of the transistor, is written, and calculating an amount of change in drain current accordance with the degradation rate, using a table in which information indicating a change in the drain current, being dependent on voltage, is written, based on actually measured data of drain current of the transistor after degradation, drain current in an initial state of a particular transistor model, and the relationship between stress time and the degradation rate of drain current.

    摘要翻译: 模拟方法包括基于其中写入晶体管的寿命数据或晶体管的劣化速率的数据的表来确定应力时间和漏极电流的劣化率之间的关系,并计算变化量 在根据劣化率的漏极电流中,使用其中写入表示依赖于电压的漏极电流的变化的信息的表,基于在劣化后晶体管的漏极电流的实际测量数据,初始的漏极电流 特定晶体管模型的状态,以及应力时间与漏极电流的劣化率之间的关系。

    Method to form high efficiency GST cell using a double heater cut
    8.
    发明授权
    Method to form high efficiency GST cell using a double heater cut 有权
    使用双加热器切割形成高效GST电池的方法

    公开(公告)号:US07888166B2

    公开(公告)日:2011-02-15

    申请号:US12724266

    申请日:2010-03-15

    IPC分类号: H01L21/00 H01L29/18

    摘要: Embodiments of the present invention provide a method that includes providing wafer including multiple cells, each cell including at least one emitter. The method further includes performing a lithographic operation in a word line direction of the wafer across the cells to form pre-heater element arrangements, performing a lithographic operation in a bit line direction of the wafer across the pre-heater element arrangements to form a pre-heater element adjacent each emitter, and performing a lithographic operation in the word line direction across a portion of the pre-heater elements to form a heater element adjacent each emitter. Other embodiments are also described.

    摘要翻译: 本发明的实施例提供一种方法,其包括提供包括多个单元的晶片,每个单元包括至少一个发射极。 所述方法还包括在晶片的字线方向上执行平版印刷操作,以形成预热器元件布置,在跨过预热器元件布置的晶片的位线方向上执行平版印刷操作,以形成预加工元件 - 加热器元件,并且跨越预热器元件的一部分在字线方向上执行光刻操作,以形成邻近每个发射器的加热元件。 还描述了其它实施例。

    Method and apparatus for harvesting file system metadata
    9.
    发明授权
    Method and apparatus for harvesting file system metadata 有权
    用于收集文件系统元数据的方法和装置

    公开(公告)号:US07801894B1

    公开(公告)日:2010-09-21

    申请号:US11262283

    申请日:2005-10-28

    IPC分类号: G06F7/00 G06F17/30

    CPC分类号: G06F17/30091

    摘要: A harvester is disclosed for harvesting metadata of managed objects (files and directories) across file systems which are generally not interoperable in an enterprise environment. Harvested metadata may include 1) file system attributes such as size, owner, recency; 2) content-specific attributes such as the presence or absence of various keywords (or combinations of keywords) within documents as well as concepts comprised of natural language entities; 3) synthetic attributes such as mathematical checksums or hashes of file contents; and 4) high-level semantic attributes that serve to classify and categorize files and documents. The classification itself can trigger an action in compliance with a policy rule. Harvested metadata are stored in a metadata repository to facilitate the automated or semi-automated application of policies.

    摘要翻译: 披露收割机用于在企业环境中通常不能互操作的文件系统上收集托管对象(文件和目录)的元数据。 收获的元数据可能包括1)文件系统属性,如大小,所有者,新近度; 2)内容特定的属性,例如文档中各种关键字(或关键字的组合)的存在或不存在以及由自然语言实体组成的概念; 3)合成属性,如数学校验和或文件内容的散列; 和4)用于对文件和文档进行分类和分类的高级语义属性。 分类本身可以触发符合策略规则的操作。 收获的元数据存储在元数据存储库中,以便于自动或半自动应用策略。