摘要:
The present invention provides methods for enhancing chemical reactions of molecules, e.g., biomolecules, with destructible surfactants. The chemical reactions may involve and/or be associate with analysis, e.g., solubilizing, separating, purifying and/or characterizing the molecules. In one aspect, the anionic surfactants of the present invention may be selectively broken up at relatively low pH. The resulting breakdown products of the surfactants may be removed from the molecule/sample with relative ease. The invention has applicability in a variety of analytical techniques.
摘要:
This invention relates to methods and reagents for the assay, detection, quantification, location, or analysis of each of a plurality of substances of interest (“analytes”) in a sample in which each substance is labeled with a cationic triarylphosphonium group. The present invention also provides MALDI mass spectrometry techniques in which the analysis of samples containing low molecule weight analytes is not obscured by matrix components. The invention also provides labeling reagents for use in labeling analytes prior to MS analysis in which the labeled analytes have a molecular weight above the useful detection threshold of MALDI techniques. In some aspects, the invention provides methods of quantitative MS analysis of components of a sample. Methods of the present invention include sensitive techniques for desorption/ionization of molecules at the picomole, femtomole, and attomole amounts. Another benefit of the present invention is that measurement of m/Z values is not complicated by the low-mass interference that a matrix normally offers, and therefore the invention provides methods of MALDI MS analysis of low molecular weight samples as well as mixtures of high and low molecular weight samples.
摘要:
Destructible surfactants and methods of using same are provided. The invention includes anionic surfactants having a dioxolane or dioxane functional group which enables the surfactant to be broken down under acidic conditions. The invention also includes methods of making anionic surfactants and methods of using anionic surfactants in a variety of applications.
摘要:
A system for assessment of irregularity in wooden material below the surface of a substrate, from above the surface of the substrate. The wooden material extending from below to above the surface of the substrate and surrounded by the substrate below the surface of the substrate. The system comprising at least one transmitter and receiver or transducer arranged to transmit energy through the material from above the surface of the substrate towards the part of the material below the surface, and to receive energy reflected from the material back through the surface, and a processor arranged to analyse the reflected energy and provide an indication of irregularity in the material below the surface of the substrate.
摘要:
Methods and structures for transistors having reduced source contact to gate spacings in semiconductor devices are disclosed. In one embodiment, a method of forming a transistor can include: forming a gate over an active area of the transistor; forming source and drain regions aligned to the gate in the active area; forming source and drain contacts over the source and drain regions, where a spacing from the gate to the source contact of the transistor is less than a spacing from the gate to the drain contact of the transistor; and using one or more modified masks for forming doping profiles for the source region and the drain region.
摘要:
Systems, apparatus, and methods for implementing enterprise level social and business information networking are provided. Users can receive relevant information about a database system and its users at an appropriate time. Users can then use this relevant information to reduce errors and limit redundant efforts. For example, an update of a record in the database can be identified, and a story created automatically about the update and sent to the users that are following the record. Which updates have stories created and which stories are to be sent to which users can be configured. Other events besides updating of records can also be tracked. For example, actions of a user that result in an event can be tracked, where such tracking can also be configurable. Subscriptions to follow an object can be automatic, and access checks can be used to ensure that unauthorized users do not see certain data.
摘要:
A simulation method includes determining a relationship between stress time and a degradation rate of drain current on a basis of a table in which data of a lifetime of a transistor, or the degradation rate of the transistor, is written, and calculating an amount of change in drain current accordance with the degradation rate, using a table in which information indicating a change in the drain current, being dependent on voltage, is written, based on actually measured data of drain current of the transistor after degradation, drain current in an initial state of a particular transistor model, and the relationship between stress time and the degradation rate of drain current.
摘要:
Embodiments of the present invention provide a method that includes providing wafer including multiple cells, each cell including at least one emitter. The method further includes performing a lithographic operation in a word line direction of the wafer across the cells to form pre-heater element arrangements, performing a lithographic operation in a bit line direction of the wafer across the pre-heater element arrangements to form a pre-heater element adjacent each emitter, and performing a lithographic operation in the word line direction across a portion of the pre-heater elements to form a heater element adjacent each emitter. Other embodiments are also described.
摘要:
A harvester is disclosed for harvesting metadata of managed objects (files and directories) across file systems which are generally not interoperable in an enterprise environment. Harvested metadata may include 1) file system attributes such as size, owner, recency; 2) content-specific attributes such as the presence or absence of various keywords (or combinations of keywords) within documents as well as concepts comprised of natural language entities; 3) synthetic attributes such as mathematical checksums or hashes of file contents; and 4) high-level semantic attributes that serve to classify and categorize files and documents. The classification itself can trigger an action in compliance with a policy rule. Harvested metadata are stored in a metadata repository to facilitate the automated or semi-automated application of policies.
摘要:
Embodiments of the present invention provide an apparatus comprising a substrate comprising an emitter layer and at least one emitter interface adjacent to the emitter layer, and a metal protective layer on a top surface of the at least one emitter interface. A method of manufacturing such an apparatus is also disclosed. The method may include performing plasma nitridation directed at column micro-trench strips. Other embodiments are also described.