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25 条记录 (耗时 0.021 秒)

    Novel peptide, novel adsorbent, adsorption unit and adsorption method
    3.
    发明申请
    Novel peptide, novel adsorbent, adsorption unit and adsorption method 审中-公开
    新型肽，新型吸附剂，吸附装置及吸附方法

    公开(公告)号：US20070059800A1

    公开(公告)日：2007-03-15

    申请号：US11599281

    申请日：2006-11-15

    申请人： Eiji Ogino ,  Takehiro Nishimoto ,  Michio Nomura ,  Shigeo Furuyoshi

    发明人： Eiji Ogino ,  Takehiro Nishimoto ,  Michio Nomura ,  Shigeo Furuyoshi

    IPC分类号： C07K14/195 ,  C07H21/04 ,  C12P21/06 ,  C12N1/21 ,  C12N15/74

    CPC分类号： C07K7/06 ,  C07K17/06 ,  C07K17/08

    摘要： The present invention provides an adsorbent, adsorption unit, and an adsorption method which make it possible to selectively adsorb an immunoglobulin and/or an immune complex present in a body fluid (for example, blood, plasma, etc.) efficiently without pretreating the body fluid. By immobilizing a compound having binding activity for an immunoglobulin and/or an immune complex on a water-insoluble carrier, an adsorbent having remarkably excellent adsorption capacity may be obtained.

    摘要翻译： 本发明提供一种吸附剂，吸附单元和吸附方法，其可以有效地选择性地吸附存在于体液（例如血液，血浆等）中的免疫球蛋白和/或免疫复合物，而无需预处理体 流体。 通过将具有免疫球蛋白和/或免疫复合物的结合活性的化合物固定在水不溶性载体上，可以获得具有极好的吸附能力的吸附剂。

    Peptide, novel adsorbent, adsorption unit and adsorption method
    4.
    发明授权
    Peptide, novel adsorbent, adsorption unit and adsorption method 有权
    肽，新型吸附剂，吸附装置及吸附方法

    公开(公告)号：US07153945B2

    公开(公告)日：2006-12-26

    申请号：US10489202

    申请日：2002-09-18

    申请人： Eiji Ogino ,  Takehiro Nishimoto ,  Michio Nomura ,  Shigeo Furuyoshi

    发明人： Eiji Ogino ,  Takehiro Nishimoto ,  Michio Nomura ,  Shigeo Furuyoshi

    IPC分类号： A61K39/00

    CPC分类号： C07K7/06 ,  C07K17/06 ,  C07K17/08

    摘要： The present invention provides an adsorbent, adsorption unit, and an adsorption method which make it possible to selectively adsorb an immunoglobulin and/or an immune complex present in a body fluid (for example, blood, plasma, etc.) efficiently without pretreating the body fluid. By immobilizing a compound having binding activity for an immunoglobulin and/or an immune complex on a water-insoluble carrier, an adsorbent having remarkably excellent adsorption capacity may be obtained.

    摘要翻译： 本发明提供一种吸附剂，吸附单元和吸附方法，其可以有效地选择性地吸附存在于体液（例如血液，血浆等）中的免疫球蛋白和/或免疫复合物，而无需预处理体 流体。 通过将具有免疫球蛋白和/或免疫复合物的结合活性的化合物固定在水不溶性载体上，可以获得具有极好的吸附能力的吸附剂。

    Process for adsorbing and removing endogenous cannabinoid
    8.
    发明授权
    Process for adsorbing and removing endogenous cannabinoid 失效
    吸收和去除内源性大麻素的方法

    公开(公告)号：US06790365B2

    公开(公告)日：2004-09-14

    申请号：US09961265

    申请日：2001-09-25

    申请人： Fumiyasu Hirai ,  Tamiji Fujimoto ,  Hiroshi Sakurai ,  Shigeo Furuyoshi

    发明人： Fumiyasu Hirai ,  Tamiji Fujimoto ,  Hiroshi Sakurai ,  Shigeo Furuyoshi

    IPC分类号： B01D1500

    CPC分类号： B01J20/261 ,  A61M1/3679 ,  B01D15/00 ,  B01J20/26 ,  G01N33/948

    摘要： There are provided an adsorbent which can effectively adsorb and remove endogenous cannabinoid in fluid, and a process for removing endogenous cannabinoid in fluid by means of the adsorbent. The adsorbent of endogenous cannabinoid comprising an adsorbent for endogenous cannabinoid comprising a water-insoluble material containing a substance whose solubility parameter &dgr; is at most 12 ((cal/cm3)1/2) is obtained. Endogenous cannabinoid in fluid can be effectively adsorbed and removed by contacting the adsorbent of endogenous cannabinoid with fluid containing endogenous cannabinoid.

    摘要翻译： 提供了能够有效吸附和去除流体中的内源大麻素的吸附剂，以及通过吸附剂除去流体中的内源大麻素的方法。 内源性大麻素的吸附剂包含内源性大麻素的吸附剂，其包含含有溶解度参数δ至多为12（（cal / cm 3）1/2）的物质的水不溶性物质）。 通过使内源大麻素的吸附剂与含有内源性大麻素的液体接触，可以有效地吸附和去除流体中的内源性大麻素。

    Low density lipoprotein/fibrinogen adsorbent and adsorption apparatus capable of whole blood treatment
    10.
    发明申请
    Low density lipoprotein/fibrinogen adsorbent and adsorption apparatus capable of whole blood treatment 审中-公开
    低密度脂蛋白/纤维蛋白原吸附剂和能够全血治疗的吸附装置

    公开(公告)号：US20060089587A1

    公开(公告)日：2006-04-27

    申请号：US10516586

    申请日：2004-04-23

    申请人： Masaru Nakatani ,  Akira Robayashi ,  Takehiro Nishimoto ,  Shigeo Furuyoshi

    发明人： Masaru Nakatani ,  Akira Robayashi ,  Takehiro Nishimoto ,  Shigeo Furuyoshi

    IPC分类号： A61M37/00

    CPC分类号： A61M1/3633 ,  A61M2202/0449 ,  A61M2202/046 ,  A61M2202/0057

    摘要： The present invention provides an adsorbent, an adsorption method, and an adsorber for efficiently adsorbing low-density lipoproteins and fibrinogen directly from a body fluid, particularly whole blood, to decrease the concentrations of these components in the body fluid with minimizing losses of useful substances such as HDL and albumin. The adsorbent includes a tryptophan derivative and a polyanionic compound which are immobilized on a water-insoluble porous carrier, wherein the amount of the immobilized polyanionic compound is 0.10 μmol to 1.5 μmol per milliliter of wet volume of the adsorbent, and the molar ratio of the amount of the immobilized tryptophan derivative to the amount of the immobilized polyanionic compound is 1 to 70. The adsorbent is capable of whole blood treatment for safely and efficiently adsorbing low-density lipoproteins and fibrinogen.

    摘要翻译： 本发明提供一种吸附剂，吸附方法和吸附剂，用于从体液，特别是全血直接有效吸附低密度脂蛋白和纤维蛋白原，以最小化有用物质的损失来降低体液中这些成分的浓度 如HDL和白蛋白。 吸附剂包括固定在水不溶性多孔载体上的色氨酸衍生物和聚阴离子化合物，其中固定化聚阴离子化合物的量为每毫升湿体积的吸附剂为0.10μmol至1.5μmol，并且所述吸附剂的摩尔比 固定化色氨酸衍生物的量相对于固定化聚阴离子化合物的量为1〜70。吸附剂能够进行全血处理，以安全有效地吸附低密度脂蛋白和纤维蛋白原。