公开(公告)号：US20230158483A1

公开(公告)日：2023-05-25

申请号：US17920135

申请日：2021-04-23

申请人： TOYOBO CO., LTD.

发明人： Ayano Higaki ,  Hirofumi Hakuba

IPC分类号： B01J41/16 ,  B01J41/04 ,  C08J5/22 ,  B01D69/02 ,  B01J47/014

CPC分类号： B01J41/16 ,  B01J41/04 ,  C08J5/2212 ,  B01D69/02 ,  B01J47/014 ,  B01D2325/02833 ,  B01D2325/02834 ,  B01D2325/022 ,  B01D2325/04 ,  B01D2325/16 ,  B01D2325/42 ,  C08J2301/08

摘要： An object of the present invention is to provide an ion-exchange membrane for simply and inexpensively separating and purifying exosomes present in a biological sample such as serum. The invention relates to a cellulose-based ion-exchange membrane containing a cellulose-based polymer having at least one hydroxyl group or acetyl group at the 2-, 3-, or 6-position being replaced with a positively charged compound. The invention also relates to a method for purifying exosomes, including subjecting a sample containing exosomes to membrane permeation by using the cellulose-based ion-exchange membrane to allow for adsorption of the exosomes, bringing the membrane into contact with a washing liquid to remove impurities, and bringing the membrane into contact with an eluent to allow for desorption of the exosomes.

公开(公告)号：US10668455B2

公开(公告)日：2020-06-02

申请号：US16221316

申请日：2018-12-14

申请人： UOP LLC

发明人： Timur V. Voskoboynikov ,  Alakananda Bhattacharyya ,  Nikolay Y. Adonin ,  Mariya N. Timofeeva ,  Sergey A. Prikhodko ,  Valentin N. Parmon

IPC分类号： B01J31/08 ,  C07C2/38 ,  B01J23/72 ,  B01J27/13 ,  B01J27/236 ,  B01J27/128 ,  B01J47/016 ,  B01J41/13 ,  B01J31/30 ,  B01J41/10 ,  B01J41/14 ,  B01J41/16 ,  C07C5/09 ,  C07C11/167 ,  C07C11/28

摘要： A catalyst and a process for using the catalyst are presented. The catalyst is a heterogeneous catalyst and includes active metal halides bonded to functional groups. The functional groups are bonded to a polymeric backbone to form the structure supporting the catalyst. The catalyst is useful for the dimerization of acetylene to convert the acetylene to a larger hydrocarbon, and in particular to dimerize acetylene to vinylacetylene.

公开(公告)号：US5438077A

公开(公告)日：1995-08-01

申请号：US183241

申请日：1994-01-19

申请人： Katsuo Komiya ,  Toshikuni Koga ,  Yoshio Kato

发明人： Katsuo Komiya ,  Toshikuni Koga ,  Yoshio Kato

IPC分类号： B01J41/14 ,  B01J20/285 ,  B01J39/18 ,  B01J41/12 ,  B01J41/16 ,  G01N30/88 ,  B01J39/20 ,  B01J39/22

CPC分类号： B01J41/12 ,  B01J39/18

摘要： An ion exchanger comprising a particle of an insoluble crosslinked polymer having alcoholic hydroxyl groups, as a base material, and a glycidyl-adduct of polyol and/or its oligomer, as a spacer, wherein ion exchange groups are attached to the spacer.

摘要翻译： 一种离子交换剂，其包含具有醇羟基的不溶性交联聚合物的颗粒，作为基料的多元醇和/或其低聚物的缩水甘油基加成物作为间隔物，其中离子交换基团连接到间隔物上。

公开(公告)号：US5354472A

公开(公告)日：1994-10-11

申请号：US981912

申请日：1992-11-23

申请人： Marc Voorhees ,  Ben F. Brian, III ,  Lloyd Forrestal

发明人： Marc Voorhees ,  Ben F. Brian, III ,  Lloyd Forrestal

IPC分类号： G01N30/00 ,  A61M1/36 ,  B01D15/08 ,  B01J20/26 ,  B01J20/28 ,  B01J20/281 ,  B01J20/285 ,  B01J20/32 ,  B01J41/12 ,  B01J41/16 ,  C08J5/22 ,  D04H1/44 ,  D04H1/46 ,  G01N30/88 ,  C02J5/20

CPC分类号： C08J5/2275 ,  A61M1/3675 ,  B01J41/16 ,  B01J41/20 ,  C08J5/2212 ,  D04H1/44 ,  D04H1/46 ,  C08J2301/08 ,  C08J2435/02

摘要： A novel biocompatible anion exchange membrane is prepared by reacting the hydroxyl groups of a chromatographic support material with a polyester-cellulose solution containing glycidyl trimethyl ammonium chloride and bis glycidyl polyethylene oxide.

摘要翻译： 通过使色谱载体材料的羟基与含有缩水甘油基三甲基氯化铵和双缩水甘油基聚环氧乙烷的聚酯 - 纤维素溶液反应来制备新的生物相容性阴离子交换膜。

公开(公告)号：US5010184A

公开(公告)日：1991-04-23

申请号：US371669

申请日：1989-06-21

申请人： Jurg Merz

发明人： Jurg Merz

IPC分类号： B01J20/281 ,  B01J20/32 ,  B01J39/22 ,  B01J41/16 ,  C08B11/14 ,  C08B31/12 ,  C08B37/00 ,  G01N30/88

CPC分类号： C08B31/125 ,  B01J20/3212 ,  B01J20/3221 ,  B01J20/3251 ,  B01J20/3253 ,  B01J20/3255 ,  C08B11/14 ,  C08B37/00

摘要： Novel ionically modified polysaccharides which contain .alpha.-glycosidic linkages, the ionic groups of which are attached to the polysaccharide component through the grouping of the formula--CO--NH--CH.sub.2 --O--,the carbonyl group being attached to the ionic group and the oxygen atom being attached to the polysaccharide component, are prepared by reacting the polysaccharides with compounds that contain N-methylolamide groups, and are used for treating effluents and, in particular, for separating mixtures of substances containing ionic components by chromatography.

摘要翻译： 含有α-糖苷键的新型离子修饰多糖，其离子基团通过式-CO-NH-CH 2 -O-（其结合到离子基团上的羰基和氧）连接到多糖组分 通过使多糖与含有N-羟甲基酰胺基团的化合物反应制备，并且用于处理流出物，特别是通过色谱法分离含有离子组分的物质的混合物。

公开(公告)号：US4263146A

公开(公告)日：1981-04-21

申请号：US50563

申请日：1979-06-21

申请人： Hans Wegmuller ,  Rudolf F. Wurster

发明人： Hans Wegmuller ,  Rudolf F. Wurster

IPC分类号： C02F1/42 ,  B01J39/22 ,  B01J41/16 ,  B01J45/00 ,  C02F1/28 ,  C08B11/145 ,  C08J5/20

CPC分类号： C02F1/286 ,  B01J39/22 ,  C08B11/145

摘要： A process for removing cationic substances from an aqueous solution, which comprises bringing the solution into contact with a cellulose-containing material which has been chemically modified anionically and in which the anionic constituent is bonded to the cellulose moiety by a grouping of the general formula--O--CH.sub.2 --N

摘要翻译： 一种从水溶液中除去阳离子物质的方法，该方法包括使溶液与已经通过阴离子化学改性的含纤维素材料接触，并且其中阴离子组分通过通式 - O-CH 2 -N <其中氮属于阴离子组分的酰胺基，氧原子与纤维素结合。

公开(公告)号：US11141710B2

公开(公告)日：2021-10-12

申请号：US16479358

申请日：2018-01-22

申请人： NAGASE CHEMTEX CORPORATION

发明人： Daisuke Nakamura ,  Yuki Maeda

IPC分类号： B01J20/22 ,  B01D15/22 ,  B01J41/16

摘要： An endotoxin adsorbent comprising a crystalline cellulose having a nitrogen atom-containing cationic group can sufficiently remove endotoxin from a material containing endotoxin to be removed and containing a substance having a cationic group and can efficiently remove endotoxin also from a highly viscous material. The nitrogen atom-containing cationic group may be typically a functional group derived from a polyvalent amine and/or a quaternary ammonium salt. The crystalline cellulose having a nitrogen atom-containing cationic group may comprise the nitrogen atom-containing cationic group at a content of 0.05 to 3 meq/dry·g in terms of anion exchange capacity.

公开(公告)号：US06911483B2

公开(公告)日：2005-06-28

申请号：US10149332

申请日：2000-12-08

申请人： John Stephen Ayers ,  David Francis Elgar ,  Margaret Mary Agnes Egan

发明人： John Stephen Ayers ,  David Francis Elgar ,  Margaret Mary Agnes Egan

IPC分类号： A23C9/146 ,  A23J1/20 ,  B01J41/16 ,  C08J5/20

CPC分类号： B01J41/16 ,  A23C9/1465 ,  A23J1/205 ,  A23V2002/00 ,  A23V2250/54242 ,  A23V2250/5434 ,  A23V2300/30

摘要： The present invention is related to a new quaternary amino (QA) anion exchanger comprising QA derivatized, hydroxy (C2-C4) alkylated and cross-linked regenerated cellulose, in which the level of derivitization with the QA-groups is 1.4 milli-equivalents per dry gram (meq/g) or greater.

摘要翻译： 本发明涉及一种新的季铵（QA）阴离子交换剂，其包含QA衍生的羟基（C 2 -C 4 -C 4 - 烷基）和交联的再生纤维素，其中 其中QA基团的衍生水平为1.4毫当量/干克（meq / g）或更高。

公开(公告)号：US5602247A

公开(公告)日：1997-02-11

申请号：US454315

申请日：1995-08-14

申请人： Eduard M ulleder ,  Heinrich Firgo

发明人： Eduard M ulleder ,  Heinrich Firgo

IPC分类号： D01F2/02 ,  B01J39/22 ,  B01J41/16 ,  C07C291/04 ,  C08B1/00 ,  C08J3/09 ,  C08J5/00 ,  C08L1/02 ,  D01F2/00 ,  D01F13/02

CPC分类号： C07C291/04 ,  C08B1/003 ,  C08J3/096 ,  C08L1/02 ,  D01F2/00 ,  C08J2301/00

摘要： The invention is concerned with a process for the production of cellulose molded bodies. This process has the following steps:(A) dissolving cellulose in an aqueous solution of a tertiary amine-oxide to produce a moldable cellulose solution,(B) molding said cellulose solution and conducting said molded cellulose solution into an aqueous precipitation bath, wherein the cellulose is precipitated, thus producing a molded body and a spent precipitation bath, and(C) purifying said spent precipitation bath by contacting said precipitation bath with an ion exchanger, thus producing a purified aqueous amine-oxide solution which, optionally after concentration, is re-used again in step (A) as a cellulose solvent. In this process, the ion exchanger comprises a cellulose carrier which has attached groups which are capable of exchanging ions.

摘要翻译： PCT No.PCT / AT95 / 00022 Sec。 371日期1995年8月14日 102（e）日期1995年8月14日PCT 1995年2月1日提交PCT公布。 WO95 / 23885 PCT公开 日期1995年9月8日本发明涉及生产纤维素成型体的方法。 该方法具有以下步骤：（A）将纤维素溶解在叔胺氧化物的水溶液中以制备可成型纤维素溶液，（B）将所述纤维素溶液模塑并将所述模制的纤维素溶液导入含水沉淀浴中，其中 纤维素被沉淀，从而生成成型体和废沉淀浴，（C）通过使所述沉淀浴与离子交换剂接触来纯化所述废沉淀浴，从而产生纯化的氧化胺水溶液，其任选地在浓缩后是 在步骤（A）中再次使用纤维素溶剂。 在该方法中，离子交换剂包括具有能够交换离子的连接基团的纤维素载体。

公开(公告)号：US5466368A

公开(公告)日：1995-11-14

申请号：US317982

申请日：1994-10-04

申请人： Lars-Erik Arvidsson ,  Hans Berg ,  Bjorn Engstrom ,  Gunnar Hagstrom

发明人： Lars-Erik Arvidsson ,  Hans Berg ,  Bjorn Engstrom ,  Gunnar Hagstrom

IPC分类号： B01D15/04 ,  B01D15/08 ,  B01J20/281 ,  B01J20/285 ,  B01J39/16 ,  B01J41/08 ,  B01J41/14 ,  B01J41/16 ,  B01J41/20 ,  B01J45/00 ,  C08L25/00 ,  C08L25/08 ,  G01N30/02 ,  G01N30/88

CPC分类号： B01J41/20 ,  B01J39/165

摘要： An ion exchanger for chromatographic separation has the structureP--S--A,wherein P is an insoluble support, S is a spacer, and A is a functional ligand. According to the invention the functional ligand A comprises two positively charged atoms, each selected from nitrogen and sulphur, at a distance of two atoms from each other, with the proviso that A can not be 4-methyl-1,4-diazabicyclo[2.2.2]octan-1-yl, 1,4,4-trimethylpiperazinium-1-yl, 1,4-dimethyl-1,4-diazabicyclo[2.2.2]octan-2-yl or 1,1,4,4,4-pentamethyl-1,4-diazabutan-1-yl.

摘要翻译： 用于色谱分离的离子交换剂具有结构P-S-A，其中P是不溶性载体，S是间隔基，A是官能配体。 根据本发明，功能性配体A包括两个彼此间隔两个原子的两个带正电荷的原子，每个原子选自氮和硫，条件是A不能是4-甲基-1,4-二氮杂双环[2.2 .2]辛-1-基，1,4,4-三甲基哌嗪-1-基，1,4-二甲基-1,4-二氮杂双环[2.2.2]辛-2-基或1,1,4,4 ，4-五甲基-1,4-二氮杂双酚-1-基。