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公开(公告)号：US20130115685A1
公开(公告)日：2013-05-09
申请号：US13647325
申请日：2012-10-08
申请人： Elizabeth A. Holmes , Shaunak Roy , John Howard , Chengwang Wang , Ian Gibbons , Timothy M. Kemp , Shize Daniel Qi
发明人： Elizabeth A. Holmes , Shaunak Roy , John Howard , Chengwang Wang , Ian Gibbons , Timothy M. Kemp , Shize Daniel Qi
IPC分类号： G01N33/50
CPC分类号： G01N21/76 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1495 , A61B5/150022 , A61B5/150099 , A61B5/150251 , A61B5/150763 , A61B5/150854 , A61B5/15142 , A61B5/157 , A61B5/412 , A61B5/417 , B01L3/50273 , B01L2300/021 , B01L2300/023 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , G01N33/50 , G01N33/53 , G01N33/5302 , G01N33/54386 , G01N2500/00 , G16H40/63 , Y02A90/26 , Y10T436/10 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/143333
摘要： This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.
摘要翻译： 本发明在医疗器械领域。 具体地说，本发明提供允许从生物流体实时检测分析物的便携式医疗装置。 所述方法和装置对于为各种医疗应用提供点护理测试特别有用。
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公开(公告)号：US20100081144A1
公开(公告)日：2010-04-01
申请号：US12576197
申请日：2009-10-08
申请人： Elizabeth A. Holmes , Shaunak Roy , John Howard , Chengwang Wang , Ian Gibbons , Timothy M. Kemp , Shize Daniel Qi
发明人： Elizabeth A. Holmes , Shaunak Roy , John Howard , Chengwang Wang , Ian Gibbons , Timothy M. Kemp , Shize Daniel Qi
CPC分类号： G01N21/76 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1495 , A61B5/150022 , A61B5/150099 , A61B5/150251 , A61B5/150763 , A61B5/150854 , A61B5/15142 , A61B5/157 , A61B5/412 , A61B5/417 , B01L3/50273 , B01L2300/021 , B01L2300/023 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , G01N33/50 , G01N33/53 , G01N33/5302 , G01N33/54386 , G01N2500/00 , G06F19/00 , G16H40/63 , Y02A90/26 , Y10T436/10 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/143333
摘要： This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.
摘要翻译： 本发明在医疗器械领域。 具体地说，本发明提供允许从生物流体实时检测分析物的便携式医疗装置。 所述方法和装置对于为各种医疗应用提供点护理测试特别有用。
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公开(公告)号：US08283155B2
公开(公告)日：2012-10-09
申请号：US12576197
申请日：2009-10-08
申请人： Elizabeth A. Holmes , Shaunak Roy , John Howard , Chengwang Wang , Ian Gibbons , Timothy M. Kemp , Shize Daniel Qi
发明人： Elizabeth A. Holmes , Shaunak Roy , John Howard , Chengwang Wang , Ian Gibbons , Timothy M. Kemp , Shize Daniel Qi
CPC分类号： G01N21/76 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1495 , A61B5/150022 , A61B5/150099 , A61B5/150251 , A61B5/150763 , A61B5/150854 , A61B5/15142 , A61B5/157 , A61B5/412 , A61B5/417 , B01L3/50273 , B01L2300/021 , B01L2300/023 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , G01N33/50 , G01N33/53 , G01N33/5302 , G01N33/54386 , G01N2500/00 , G06F19/00 , G16H40/63 , Y02A90/26 , Y10T436/10 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/143333
摘要： This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.
摘要翻译： 本发明在医疗器械领域。 具体地说，本发明提供允许从生物流体实时检测分析物的便携式医疗装置。 所述方法和装置对于为各种医疗应用提供点护理测试特别有用。
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公开(公告)号：US08679407B2
公开(公告)日：2014-03-25
申请号：US11388415
申请日：2006-03-24
申请人： Elizabeth A. Holmes , Ian Gibbons , John Howard , Shaunak Roy , Chengwang Wang , Timothy M. Kemp
发明人： Elizabeth A. Holmes , Ian Gibbons , John Howard , Shaunak Roy , Chengwang Wang , Timothy M. Kemp
IPC分类号： G01N15/06
CPC分类号： G01N21/76 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1495 , A61B5/150022 , A61B5/150099 , A61B5/150251 , A61B5/150763 , A61B5/150854 , A61B5/15142 , A61B5/157 , A61B5/412 , A61B5/417 , B01L3/50273 , B01L2300/021 , B01L2300/023 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , G01N33/50 , G01N33/53 , G01N33/5302 , G01N33/54386 , G01N2500/00 , G06F19/00 , G16H40/63 , Y02A90/26 , Y10T436/10 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/143333
摘要： This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.
摘要翻译： 本发明在医疗器械领域。 具体地说，本发明提供允许从生物流体实时检测分析物的便携式医疗装置。 所述方法和装置对于为各种医疗应用提供点护理测试特别有用。
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公开(公告)号：US07635594B2
公开(公告)日：2009-12-22
申请号：US11389409
申请日：2006-03-24
申请人： Elizabeth A. Holmes , Shaunak Roy , John Howard , Chengwang Wang , Ian Gibbons , Timothy M. Kemp , Shize Daniel Qi
发明人： Elizabeth A. Holmes , Shaunak Roy , John Howard , Chengwang Wang , Ian Gibbons , Timothy M. Kemp , Shize Daniel Qi
CPC分类号： G01N21/76 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1495 , A61B5/150022 , A61B5/150099 , A61B5/150251 , A61B5/150763 , A61B5/150854 , A61B5/15142 , A61B5/157 , A61B5/412 , A61B5/417 , B01L3/50273 , B01L2300/021 , B01L2300/023 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , G01N33/50 , G01N33/53 , G01N33/5302 , G01N33/54386 , G01N2500/00 , G06F19/00 , G16H40/63 , Y02A90/26 , Y10T436/10 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/143333
摘要： This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.
摘要翻译： 本发明在医疗器械领域。 具体地说，本发明提供允许从生物流体实时检测分析物的便携式医疗装置。 所述方法和装置对于为各种医疗应用提供点护理测试特别有用。
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公开(公告)号：US20120052561A1
公开(公告)日：2012-03-01
申请号：US13286168
申请日：2011-10-31
申请人： Elizabeth A. Holmes , Shaunak Roy , John Howard , Chengwang Wang , Ian Gibbons , Timothy M. Kemp , Shize Daniel Qi
发明人： Elizabeth A. Holmes , Shaunak Roy , John Howard , Chengwang Wang , Ian Gibbons , Timothy M. Kemp , Shize Daniel Qi
CPC分类号： G01N21/76 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1495 , A61B5/150022 , A61B5/150099 , A61B5/150251 , A61B5/150763 , A61B5/150854 , A61B5/15142 , A61B5/157 , A61B5/412 , A61B5/417 , B01L3/50273 , B01L2300/021 , B01L2300/023 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , G01N33/50 , G01N33/53 , G01N33/5302 , G01N33/54386 , G01N2500/00 , G16H40/63 , Y02A90/26 , Y10T436/10 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/143333
摘要： This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.
摘要翻译： 本发明在医疗器械领域。 具体地说，本发明提供允许从生物流体实时检测分析物的便携式医疗装置。 所述方法和装置对于为各种医疗应用提供点护理测试特别有用。
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公开(公告)号：US08841076B2
公开(公告)日：2014-09-23
申请号：US11388823
申请日：2006-03-24
申请人： Elizabeth A. Holmes , Ian Gibbons , Timothy M. Kemp , John Howard , Shaunak Roy
发明人： Elizabeth A. Holmes , Ian Gibbons , Timothy M. Kemp , John Howard , Shaunak Roy
CPC分类号： G01N21/76 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1495 , A61B5/150022 , A61B5/150099 , A61B5/150251 , A61B5/150763 , A61B5/150854 , A61B5/15142 , A61B5/157 , A61B5/412 , A61B5/417 , B01L3/50273 , B01L2300/021 , B01L2300/023 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , G01N33/50 , G01N33/53 , G01N33/5302 , G01N33/54386 , G01N2500/00 , G06F19/00 , G16H40/63 , Y02A90/26 , Y10T436/10 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/143333
摘要： This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.
摘要翻译： 本发明在医疗器械领域。 具体地说，本发明提供允许从生物流体实时检测分析物的便携式医疗装置。 所述方法和装置对于为各种医疗应用提供点护理测试特别有用。
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公开(公告)号：US09075046B2
公开(公告)日：2015-07-07
申请号：US12625430
申请日：2009-11-24
申请人： Timothy M. Kemp , Chris Todd , Ron Oral , Shulin Zeng , John Howard , Jeff Fenton
发明人： Timothy M. Kemp , Chris Todd , Ron Oral , Shulin Zeng , John Howard , Jeff Fenton
IPC分类号： G01N21/75 , G01N33/53 , B01L3/00 , A61B5/15 , A61B5/145 , A61B5/00 , G01N33/50 , A61B5/155 , G06F19/00 , A61B5/151 , A61B5/157 , A61B5/1495
CPC分类号： G01N21/76 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1495 , A61B5/150022 , A61B5/150099 , A61B5/150251 , A61B5/150763 , A61B5/150854 , A61B5/15142 , A61B5/157 , A61B5/412 , A61B5/417 , B01L3/50273 , B01L2300/021 , B01L2300/023 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , G01N33/50 , G01N33/53 , G01N33/5302 , G01N33/54386 , G01N2500/00 , G06F19/00 , G16H40/63 , Y02A90/26 , Y10T436/10 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/143333
摘要： This invention is in the field of medical devices. Specifically, the present invention provides fluidic systems having a plurality of reaction sites surrounded by optical barriers to reduce the amount of optical cross-talk between signals detected from various reaction sites. The invention also provides a method of manufacturing fluidic systems and methods of using the systems.
摘要翻译： 本发明在医疗器械领域。 具体地说，本发明提供流体系统，其具有由光学屏障包围的多个反应位点，以减少从各个反应位点检测的信号之间的光学串扰量。 本发明还提供了制造流体系统的方法和使用该系统的方法。
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公开(公告)号：US20100074799A1
公开(公告)日：2010-03-25
申请号：US12625430
申请日：2009-11-24
申请人： Timothy M. Kemp , Chris Todd , Ron Oral , Shulin Zeng , John Howard , Jeff Fenton
发明人： Timothy M. Kemp , Chris Todd , Ron Oral , Shulin Zeng , John Howard , Jeff Fenton
CPC分类号： G01N21/76 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1495 , A61B5/150022 , A61B5/150099 , A61B5/150251 , A61B5/150763 , A61B5/150854 , A61B5/15142 , A61B5/157 , A61B5/412 , A61B5/417 , B01L3/50273 , B01L2300/021 , B01L2300/023 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , G01N33/50 , G01N33/53 , G01N33/5302 , G01N33/54386 , G01N2500/00 , G06F19/00 , G16H40/63 , Y02A90/26 , Y10T436/10 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/143333
摘要： This invention is in the field of medical devices. Specifically, the present invention provides fluidic systems having a plurality of reaction sites surrounded by optical barriers to reduce the amount of optical cross-talk between signals detected from various reaction sites. The invention also provides a method of manufacturing fluidic systems and methods of using the systems.
摘要翻译： 本发明在医疗器械领域。 具体地说，本发明提供流体系统，其具有由光学屏障包围的多个反应位点，以减少从各个反应位点检测的信号之间的光学串扰量。 本发明还提供了制造流体系统的方法和使用该系统的方法。
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公开(公告)号：US06834365B2
公开(公告)日：2004-12-21
申请号：US09907387
申请日：2001-07-17
IPC分类号： G06F1100
CPC分类号： G06F11/3636 , G06F11/3495
摘要： An integrated circuit real-time data tracing apparatus for analyzing microprocessor based computer systems for monitoring, in real-time, parameters sufficient to define the load and store operations information that the embedded core controller may assert, and process information during events. Integral on this single chip apparatus is a data trace unit designed to access control, address, and data signal lines required to monitor the embedded core controller's activities; perform data tracing independent of instruction tracing; synchronize with an instruction trace stream; allow for selection of multiple ranges for data tracing; report lost events to a FIFO array; and, output strobe signals to give a cycle accurate indication of when an event has been captured.
摘要翻译： 一种用于分析基于微处理器的计算机系统的集成电路实时数据跟踪装置，用于实时监测足以定义嵌入式核心控制器可以断言的负载和存储操作信息的参数，以及在事件期间处理信息。 该单芯片设备的一体是数据跟踪单元，用于访问监控嵌入式核心控制器活动所需的控制，地址和数据信号线; 执行独立于指令跟踪的数据跟踪; 与指令跟踪流同步; 允许选择多个范围进行数据跟踪; 将丢失的事件报告给FIFO数组; 并且输出选通信号以给出何时捕获事件的循环精确指示。
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