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公开(公告)号：US20130267880A1
公开(公告)日：2013-10-10
申请号：US13441539
申请日：2012-04-06
申请人： Emma Kim Luong-Van , Isabel Rodriguez , Hong Yee Low , Audrey Yoke Yee Ho , Sriram Natarajan , Noha Elmouelhi , Kevin Cooper , Murty Vyakarnam , Chee Tiong Lim
发明人： Emma Kim Luong-Van , Isabel Rodriguez , Hong Yee Low , Audrey Yoke Yee Ho , Sriram Natarajan , Noha Elmouelhi , Kevin Cooper , Murty Vyakarnam , Chee Tiong Lim
CPC分类号： B29C59/14 , A61F13/00017 , A61F13/00063 , A61F2013/00472 , B29K2023/12
摘要： A blood clotting substrate and device which has a plurality of oxygen plasma-treated polypropylene pillars extending from the surface of a polypropylene film.
摘要翻译： 一种凝血基质和装置，其具有从聚丙烯膜的表面延伸的多个氧等离子体处理的聚丙烯支柱。
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公开(公告)号：US08969648B2
公开(公告)日：2015-03-03
申请号：US13441539
申请日：2012-04-06
申请人： Emma Kim Luong-Van , Isabel Rodriguez , Hong Yee Low , Audrey Yoke Yee Ho , Sriram Natarajan , Noha Elmouelhi , Kevin Cooper , Murty Vyakarnam , Chee Tiong Lim
发明人： Emma Kim Luong-Van , Isabel Rodriguez , Hong Yee Low , Audrey Yoke Yee Ho , Sriram Natarajan , Noha Elmouelhi , Kevin Cooper , Murty Vyakarnam , Chee Tiong Lim
IPC分类号： A61F13/00
CPC分类号： B29C59/14 , A61F13/00017 , A61F13/00063 , A61F2013/00472 , B29K2023/12
摘要： A blood clotting substrate and device which has a plurality of oxygen plasma-treated polypropylene pillars extending from the surface of a polypropylene film.
摘要翻译： 一种凝血基质和装置，其具有从聚丙烯膜的表面延伸的多个氧等离子体处理的聚丙烯支柱。
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公开(公告)号：US20130288225A1
公开(公告)日：2013-10-31
申请号：US13458825
申请日：2012-04-27
申请人： Noha Elmouelhi , Sriram Natarajan , Kevin Cooper , Murty Vyakarnam , Chee Tiong Lim , Emma Kim Luong-Van , Isabel Rodriguez , Hong Yee Low , Audrey Yoke Yee Ho
发明人： Noha Elmouelhi , Sriram Natarajan , Kevin Cooper , Murty Vyakarnam , Chee Tiong Lim , Emma Kim Luong-Van , Isabel Rodriguez , Hong Yee Low , Audrey Yoke Yee Ho
IPC分类号： C12N5/078
CPC分类号： G01N33/491
摘要： A method of separating blood by providing a horizontal substrate having a plurality of oxygen plasma-treated polypropylene pillars extending from the surface of a polypropylene film, depositing a whole blood sample on an upper surface of the substrate, collecting red blood cells on the upper surface of the pillars and permitting remaining components of said whole blood sample to flow downward and through the pillars.
摘要翻译： 提供一种通过提供具有从聚丙烯薄膜表面延伸的多个氧等离子体处理的聚丙烯支柱的水平基底分离血液的方法，将全血样品沉积在基底的上表面上，在上表面上收集红细胞 并且允许所述全血样品的剩余组分向下流动并穿过支柱。
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4.发明授权Super-hydrophobic hierarchical structures, method of forming them and medical devices incorporating them 有权超疏水分层结构，形成方法和结合它们的医疗器械公开(公告)号：US08926881B2
公开(公告)日：2015-01-06
申请号：US13441496
申请日：2012-04-06
申请人： Audrey Yoke Yee Ho , Isabel Rodriguez , Hong Yee Low , Emma Kim Luong-Van , Sriram Natarajan , Noha Elmouelhi , Kevin Cooper , Chee Tiong Lim
发明人： Audrey Yoke Yee Ho , Isabel Rodriguez , Hong Yee Low , Emma Kim Luong-Van , Sriram Natarajan , Noha Elmouelhi , Kevin Cooper , Chee Tiong Lim
IPC分类号： B32B3/30
CPC分类号： A61L31/14 , A61L27/50 , A61L27/56 , A61L31/146 , A61L2400/18 , B82Y30/00 , B82Y40/00 , Y10T428/24355
摘要： Synthetic polymer substrates comprising a hierarchical surface structure of multiple domes and multiple pillars on said domes, wherein said substrate is a synthetic polymer film, said domes have diameters in the range from about 5 μm to about 400 μm, heights in the range from about 2.5 μm and about 500 μm, and said pillars have diameters in the range from about 20 nm to about 5 μm and aspect ratios of from about 2 to about 50, and methods of making and using them.
摘要翻译： 合成聚合物基材，其包含在所述圆顶上的多个圆顶和多个柱的分层表面结构，其中所述基材是合成聚合物膜，所述圆顶的直径在约5μm至约400μm的范围内，高度在约2.5 μm和约500μm，并且所述柱具有在约20nm至约5μm范围内的直径和约2至约50的纵横比，以及制造和使用它们的方法。
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5.发明申请SUPER-HYDROPHOBIC HIERARCHICAL STRUCTURES, METHOD OF FORMING THEM AND MEDICAL DEVICES INCORPORATING THEM 有权超级疏水分层结构，其形成方法和与其配套的医疗器械公开(公告)号：US20130266761A1
公开(公告)日：2013-10-10
申请号：US13441496
申请日：2012-04-06
申请人： Audrey Yoke Yee Ho , Isabel Rodriguez , Hong Yee Low , Emma Kim Luong-Van , Sriram Natarajan , Noha Elmouelhi , Kevin Cooper , Chee Tiong Lim
发明人： Audrey Yoke Yee Ho , Isabel Rodriguez , Hong Yee Low , Emma Kim Luong-Van , Sriram Natarajan , Noha Elmouelhi , Kevin Cooper , Chee Tiong Lim
CPC分类号： A61L31/14 , A61L27/50 , A61L27/56 , A61L31/146 , A61L2400/18 , B82Y30/00 , B82Y40/00 , Y10T428/24355
摘要： Synthetic polymer substrates comprising a hierarchical surface structure of multiple domes and multiple pillars on said domes, wherein said substrate is a synthetic polymer film, said domes have diameters in the range from about 5 μm to about 400 μm, heights in the range from about 2.5 μm and about 500 μm, and said pillars have diameters in the range from about 20 nm to about 5 μm and aspect ratios of from about 2 to about 50, and methods of making and using them.
摘要翻译： 合成聚合物基材，其包括多个圆顶的分层表面结构和在所述圆顶上的多个柱，其中所述基材是合成聚合物膜，所述圆顶的直径在约5μm至约400μm的范围内，高度在约2.5 并且所述支柱具有在约20nm至约5μm范围内的直径和约2至约50的纵横比，以及制造和使用它们的方法。
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公开(公告)号：US09492952B2
公开(公告)日：2016-11-15
申请号：US13435544
申请日：2012-03-30
申请人： Emma Kim Luong-Van , Isabel Rodriguez , Hong Yee Low , Noha Elmouelhi , Kevin Cooper , Sriram Natarajan , Murty N. Vyakarnam , Chee Tiong Lim
发明人： Emma Kim Luong-Van , Isabel Rodriguez , Hong Yee Low , Noha Elmouelhi , Kevin Cooper , Sriram Natarajan , Murty N. Vyakarnam , Chee Tiong Lim
CPC分类号： B29C33/52 , A61B2017/00871 , A61B2017/00938 , A61B2017/00942 , A61B2017/00951 , A61L27/18 , A61L31/06 , Y10T428/24355 , C08L67/04
摘要： A polydioxanone film comprising substantially cylindrical polydioxanone pillars on at least one side thereof, said pillars having diameters from about 0.2 μm to about 3 μm, and heights from about 2 μm to about 20 μm from the surface of the film, a process for adsorbing proteins using the film and medical devices incorporating the film.
摘要翻译： 一种聚二恶烷酮薄膜，其至少在其一面上包括基本上圆柱形的聚二恶烷酮柱，所述柱具有约0.2μm至约3μm的直径，以及距膜的约2μm至约20μm的高度，用于吸附蛋白质的方法 使用包含该膜的胶片和医疗装置。
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公开(公告)号：US20120251611A1
公开(公告)日：2012-10-04
申请号：US13435544
申请日：2012-03-30
申请人： Emma Kim Luong-Van , Isabel Rodriguez , Hong Yee Low , Noha Elmouelhi , Kevin Cooper , Sriram Natarajan , Murty N. Vyakarnam , Chee Tiong Lim
发明人： Emma Kim Luong-Van , Isabel Rodriguez , Hong Yee Low , Noha Elmouelhi , Kevin Cooper , Sriram Natarajan , Murty N. Vyakarnam , Chee Tiong Lim
CPC分类号： B29C33/52 , A61B2017/00871 , A61B2017/00938 , A61B2017/00942 , A61B2017/00951 , A61L27/18 , A61L31/06 , Y10T428/24355 , C08L67/04
摘要： A polydioxanone film comprising substantially cylindrical polydioxanone pillars on at least one side thereof, said pillars having diameters from about 0.2 μm to about 3 μm, and heights from about 2 μm to about 20 μm from the surface of the film, a process for adsorbing proteins using the film and medical devices incorporating the film.
摘要翻译： 一种聚二恶烷酮薄膜，其至少在其一面上包括基本上圆柱形的聚二恶烷酮柱，所述柱具有约0.2μm至约3μm的直径，以及距膜的约2μm至约20μm的高度，用于吸附蛋白质的方法 使用包含该膜的胶片和医疗装置。
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公开(公告)号：US20120143228A1
公开(公告)日：2012-06-07
申请号：US13340331
申请日：2011-12-29
申请人： Sriram Natarajan , Joseph J. Hammer , Kevin Cooper , Murty N. Vyakarnam , Hong Yee Low , Isabel Rodriguez , Chee Tiong Lim , Audrey Yoke Yee Ho
发明人： Sriram Natarajan , Joseph J. Hammer , Kevin Cooper , Murty N. Vyakarnam , Hong Yee Low , Isabel Rodriguez , Chee Tiong Lim , Audrey Yoke Yee Ho
CPC分类号： A61F2/0063 , A61B2017/00871 , A61B2017/00938 , A61B2017/00942 , A61B2017/00951 , A61L31/048 , A61L31/06 , A61L31/10 , B29C33/52 , C09J7/21 , C09J7/30 , C09J2201/32 , C09J2400/263 , C08L23/12 , C08L67/04
摘要： A laminate and process of making the laminate is disclosed comprising: a surgical mesh having first and second surfaces; and an adhesive structure having adhesive and non-adhesive surfaces, wherein the non-adhesive surface of the adhesive structure is laminated to at least one of said first and second surfaces of said surgical mesh, and the adhesive surface of said adhesive structure has protrusions extending therefrom comprising a resin having a Young's modulus of greater than 17 MPa, which protrusions are of sufficiently low diameter to promote adhesion by increasing physical attractive forces between the adhesive structure and a target surface, as measured by shear adhesion.
摘要翻译： 公开了层压体和制造层压体的方法，包括：具有第一和第二表面的外科手术网; 以及具有粘合剂和非粘合剂表面的粘合剂结构，其中粘合剂结构的非粘合表面被层压到所述外科手术网的所述第一和第二表面中的至少一个上，并且所述粘合剂结构的粘合剂表面具有延伸的突起 其包含杨氏模量大于17MPa的树脂，该突起的直径足够小，以通过剪切粘合力测量来增加粘合剂结构和目标表面之间的物理吸引力来促进粘合。
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公开(公告)号：US08104660B2
公开(公告)日：2012-01-31
申请号：US11418003
申请日：2006-05-03
CPC分类号： B23K20/005 , B06B3/00 , B23K2101/40 , H01L24/45 , H01L24/78 , H01L24/85 , H01L2224/45124 , H01L2224/45144 , H01L2224/45147 , H01L2224/78301 , H01L2224/85205 , H01L2924/00014 , H01L2924/01013 , H01L2924/01019 , H01L2924/01029 , H01L2924/01033 , H01L2924/01079 , H01L2924/14 , H01L2224/48 , H01L2924/00 , H01L2924/00015
摘要： A transducer is provided that comprises a horn having a longitudinal axis, a bonding tool attached to the horn, and an ultrasonic generator attached to the horn and spaced from the bonding tool along the longitudinal axis of the horn. A flexure is attached to the horn between the bonding tool and the ultrasonic generator for supporting the horn whereby to increase its dynamic rigidity in directions transverse to the longitudinal axis.
摘要翻译： 提供了一种换能器，其包括具有纵向轴线的喇叭，附接到喇叭的接合工具以及附接到喇叭并沿着喇叭的纵向轴线与接合工具隔开的超声波发生器。 在焊接工具和超声波发生器之间的喇叭上附接挠曲件，用于支撑喇叭，从而增加其横向于纵向轴线的方向的动态刚度。
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公开(公告)号：US07537148B2
公开(公告)日：2009-05-26
申请号：US11250260
申请日：2005-10-14
IPC分类号： B23K1/06
CPC分类号： B06B3/00 , H01L24/78 , H01L2224/78 , H01L2224/78301 , H01L2224/78308 , H01L2924/00014 , H01L2924/01005 , H01L2924/01006 , H01L2924/01033 , H01L2224/48 , H01L2224/45099 , H01L2924/00
摘要： A bonding apparatus such as an ultrasonic transducer is provided that comprises an oscillation amplification device having a longitudinal axis and a substantially triangular cross-sectional area on a plane that is orthogonal to the longitudinal axis. An ultrasonic driver is coupled to the oscillation amplification device at a first position along the longitudinal axis and a bonding tool is mounted to the oscillation amplification device at a second position along the longitudinal axis spaced from the first position.
摘要翻译： 提供了诸如超声波换能器的接合装置，其包括在与纵向轴线正交的平面上具有纵向轴线和基本上三角形的横截面积的振荡放大装置。 超声波驱动器在沿着纵向轴线的第一位置耦合到振荡放大装置，并且接合工具沿着与第一位置间隔开的纵向轴线的第二位置安装到振荡放大装置。
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