Protease enzyme inhibitors
    8.
    发明申请
    Protease enzyme inhibitors 审中-公开
    蛋白酶抑制剂

    公开(公告)号:US20060003943A1

    公开(公告)日:2006-01-05

    申请号:US11221445

    申请日:2005-09-08

    IPC分类号: A61K38/05 C07K5/06

    CPC分类号: A61K47/60

    摘要: The present invention relates to compounds having the general formula: [Poly]—[(L)z—[R—CHO]]y wherein [Poly] is a water-soluble, non-peptidic polymer component, L is an optionally present linking group, and RCHO is a substrate capable of interacting with one or more protease enzymes to reversibly inhibit said enzyme, and wherein said substrate comprises a peptide or peptide-like aldehyde. The index z is 0 when linking groups are absent and z is 1 when linking groups are present. The index y is at least 1. The inhibitors of the present invention are suitable for use in personal care compositions, inter alia, body washes, shampoos, and skin creams.

    摘要翻译: 本发明涉及具有以下通式的化合物:<?in-line-formula description =“In-line Formulas”end =“lead”?> [Poly] - [(L)z - [R-CHO]] <?in-line-formula description =“In-line Formulas”end =“tail”?>其中[Poly]是一种水溶性非肽聚合物 L是任选存在的连接基团,并且RCHO是能够与一种或多种蛋白酶相互作用以可逆地抑制所述酶的底物,并且其中所述底物包含肽或肽样醛。 当不存在连接基团时,索引z为0,当存在连接基团时,z为1。 指数y至少为1.本发明的抑制剂适用于个人护理组合物,特别是身体洗涤剂,洗发剂和护肤霜。

    Absorbent articles having a breathable stretch laminate
    10.
    发明申请
    Absorbent articles having a breathable stretch laminate 失效
    具有透气拉伸层压板的吸收制品

    公开(公告)号:US20070167929A1

    公开(公告)日:2007-07-19

    申请号:US11333135

    申请日:2006-01-17

    IPC分类号: A61F13/15

    摘要: An absorbent article may comprise a topsheet; a backsheet joined with the topsheet; an absorbent core between the topsheet and backsheet; and an elastic element comprising a breathable stretch laminate. The breathable stretch laminate may comprise a first substrate; and an elastic member joined to the first substrate, wherein said elastic member comprises a polyurethane. The breathable stretch laminate may exhibit a MVTR greater than about 300 grams per square meter per 24 hours and a force relaxation of less than about 50% after about 10 hours at 100° F. and 50% elongation.

    摘要翻译: 吸收制品可以包括顶片; 与顶片接合的底片; 在顶片和底片之间的吸收芯; 以及包括透气拉伸层压体的弹性元件。 透气拉伸叠层可以包括第一基底; 以及与第一基板接合的弹性构件,其中所述弹性构件包括聚氨酯。 透气拉伸层压材料可以表现出大于约300克/平方米/ 24小时的MVTR和在100°F和50%伸长率下约10小时后的力松弛小于约50%。