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1.发明申请公开(公告)号：US20110020398A1
公开(公告)日：2011-01-27
申请号：US12653751
申请日：2009-12-17
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , C12N2770/24222
摘要： The invention relates to peptide compositions for use in the preparation of pharmaceutical compositions against hepatitis C virus, as well as corresponding methods.
摘要翻译： 本发明涉及用于制备抗丙型肝炎病毒的药物组合物的肽组合物，以及相应的方法。
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2.发明授权公开(公告)号：US08293528B2
公开(公告)日：2012-10-23
申请号：US12653751
申请日：2009-12-17
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , C12N2770/24222
摘要： The invention relates to peptide compositions for use in the preparation of pharmaceutical compositions against hepatitis C virus, as well as corresponding methods.
摘要翻译： 本发明涉及用于制备抗丙型肝炎病毒的药物组合物的肽组合物，以及相应的方法。
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3.发明申请公开(公告)号：US20070072176A1
公开(公告)日：2007-03-29
申请号：US11503245
申请日：2006-08-11
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , C12N2770/24222
摘要： The invention relates to peptide compositions for use in the preparation of pharmaceutical compositions against hepatitis C virus, as well as corresponding methods.
摘要翻译： 本发明涉及用于制备抗丙型肝炎病毒的药物组合物的肽组合物，以及相应的方法。
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公开(公告)号：US20130011435A1
公开(公告)日：2013-01-10
申请号：US13388826
申请日：2010-08-06
CPC分类号： A61K39/29 , A61K39/12 , A61K39/292 , A61K2039/53 , A61K2039/545 , A61K2039/57 , C12N7/00 , C12N9/1252 , C12N15/86 , C12N2710/10043 , C12N2710/24143 , C12N2730/10134 , C12Y207/07007
摘要： The present invention provides a composition comprising hepatitis B virus (HBV) component(s), and which may be either nucleic acid- or polypeptide-based as well as nucleic acid molecules and vectors encoding such HBV component(s). It also relates to infectious viral particles and host cells comprising such nucleic acid molecules or vectors. It also provides composition and kits of parts comprising such nucleic acid molecules, vectors, infectious viral particles or host cells and the therapeutic use thereof for preventing or treating HBV infections.
摘要翻译： 本发明提供包含乙型肝炎病毒（HBV）组分的组合物，其可以是基于核酸或多肽的核酸分子以及编码这样的HBV组分的载体。 它还涉及包含这种核酸分子或载体的感染性病毒颗粒和宿主细胞。 它还提供包含这种核酸分子，载体，感染性病毒颗粒或宿主细胞的组分和试剂盒以及用于预防或治疗HBV感染的治疗用途。
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公开(公告)号：US10076570B2
公开(公告)日：2018-09-18
申请号：US13423193
申请日：2012-03-17
IPC分类号： A61K39/00 , A61K39/29 , C07K14/005 , A61K39/12
CPC分类号： A61K39/292 , A61K39/12 , A61K2039/53 , A61K2039/545 , C07K14/005 , C12N2710/10343 , C12N2710/24143 , C12N2730/10134 , C12N2770/24222
摘要： The present invention provides a composition comprising hepatitis B virus (HBV) component(s), and which may be either nucleic acid- or polypeptide-based as well as nucleic acid molecules and vectors encoding such HBV component(s). It also relates to infectious viral particles and host cells comprising such nucleic acid molecules or vectors. It also provides composition and kits of parts comprising such nucleic acid molecules, vectors, infectious viral particles or host cells and the therapeutic use thereof for preventing or treating HBV infections.
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公开(公告)号：US09393299B2
公开(公告)日：2016-07-19
申请号：US13388826
申请日：2010-08-06
CPC分类号： A61K39/29 , A61K39/12 , A61K39/292 , A61K2039/53 , A61K2039/545 , A61K2039/57 , C12N7/00 , C12N9/1252 , C12N15/86 , C12N2710/10043 , C12N2710/24143 , C12N2730/10134 , C12Y207/07007
摘要： The present invention provides a composition comprising hepatitis B virus (HBV) component(s), and which may be either nucleic acid- or polypeptide-based as well as nucleic acid molecules and vectors encoding such HBV component(s). It also relates to infectious viral particles and host cells comprising such nucleic acid molecules or vectors. It also provides composition and kits of parts comprising such nucleic acid molecules, vectors, infectious viral particles or host cells and the therapeutic use thereof for preventing or treating HBV infections.
摘要翻译： 本发明提供包含乙型肝炎病毒（HBV）组分的组合物，其可以是基于核酸或多肽的核酸分子以及编码这样的HBV组分的载体。 它还涉及包含这种核酸分子或载体的感染性病毒颗粒和宿主细胞。 它还提供包含这种核酸分子，载体，感染性病毒颗粒或宿主细胞的组分和试剂盒以及用于预防或治疗HBV感染的治疗用途。
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公开(公告)号：US20120251569A1
公开(公告)日：2012-10-04
申请号：US13423193
申请日：2012-03-17
IPC分类号： A61K39/29 , C07K4/02 , C12N15/54 , C12N15/51 , A61P31/20 , A61P37/02 , A61P37/04 , C12N9/12 , C12N15/62 , C12N15/63 , C12N7/01 , C12N1/21 , C12N1/19 , C12N5/10 , C07K14/02
CPC分类号： A61K39/292 , A61K39/12 , A61K2039/53 , A61K2039/545 , C07K14/005 , C12N2710/10343 , C12N2710/24143 , C12N2730/10134 , C12N2770/24222
摘要： The present invention provides a composition comprising hepatitis B virus (HBV) component(s), and which may be either nucleic acid- or polypeptide-based as well as nucleic acid molecules and vectors encoding such HBV component(s). It also relates to infectious viral particles and host cells comprising such nucleic acid molecules or vectors. It also provides composition and kits of parts comprising such nucleic acid molecules, vectors, infectious viral particles or host cells and the therapeutic use thereof for preventing or treating HBV infections.
摘要翻译： 本发明提供包含乙型肝炎病毒（HBV）组分的组合物，其可以是基于核酸或多肽的核酸分子以及编码这样的HBV组分的载体。 它还涉及包含这种核酸分子或载体的感染性病毒颗粒和宿主细胞。 它还提供包含这种核酸分子，载体，感染性病毒颗粒或宿主细胞的组分和试剂盒以及用于预防或治疗HBV感染的治疗用途。
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公开(公告)号：US09512412B2
公开(公告)日：2016-12-06
申请号：US14232082
申请日：2012-07-12
CPC分类号： C12N9/1252 , A61K38/00 , A61K39/292 , A61K2039/53 , C07K14/005 , C07K2319/02 , C07K2319/03 , C07K2319/40 , C12N7/00 , C12N9/1276 , C12N9/22 , C12N2730/10122 , C12N2730/10134 , C12N2799/022 , C12N2799/023 , C12P21/02 , C12Y207/07007 , C12Y301/26004
摘要： The present invention relates to polymerase HBV mutant polypeptides comprising a mutated polymerase domain which is functionally disrupted for polymerase activity and fusion proteins comprising such polymerase mutant polypeptide. The present invention also relates to a nucleic acid molecule and an expression vector for expressing said polymerase mutant polypeptide as well as a composition which can be used for eliciting an immune response to HBV with the goal of providing a protective or therapeutic effect against HBV infection.
摘要翻译： 本发明涉及聚合酶HBV突变体多肽，其包含功能性地破坏聚合酶活性的突变聚合酶结构域和包含该聚合酶突变体多肽的融合蛋白。 本发明还涉及用于表达所述聚合酶突变体多肽的核酸分子和表达载体以及可用于引发对HBV的免疫应答的组合物，目的是提供对HBV感染的保护或治疗作用。
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公开(公告)号：US20140287480A1
公开(公告)日：2014-09-25
申请号：US14232082
申请日：2012-07-12
IPC分类号： C12N9/12
CPC分类号： C12N9/1252 , A61K38/00 , A61K39/292 , A61K2039/53 , C07K14/005 , C07K2319/02 , C07K2319/03 , C07K2319/40 , C12N7/00 , C12N9/1276 , C12N9/22 , C12N2730/10122 , C12N2730/10134 , C12N2799/022 , C12N2799/023 , C12P21/02 , C12Y207/07007 , C12Y301/26004
摘要： The present invention relates to polymerase HBV mutant polypeptides comprising a mutated polymerase domain which is functionally disrupted for polymerase activity and fusion proteins comprising such polymerase mutant polypeptide. The present invention also relates to a nucleic acid molecule and an expression vector for expressing said polymerase mutant polypeptide as well as a composition which can be used for eliciting an immune response to HBV with the goal of providing a protective or therapeutic effect against HBV infection.
摘要翻译： 本发明涉及聚合酶HBV突变体多肽，其包含功能性地破坏聚合酶活性的突变聚合酶结构域和包含该聚合酶突变体多肽的融合蛋白。 本发明还涉及用于表达所述聚合酶突变体多肽的核酸分子和表达载体以及可用于引发对HBV的免疫应答的组合物，目的是提供对HBV感染的保护或治疗作用。
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