-
公开(公告)号：US20050089855A1
公开(公告)日：2005-04-28
申请号：US10484690
申请日：2002-07-22
申请人： Gilbert ThilI , Philippe Jais , Pascale Grel , Sandrine Mace
发明人： Gilbert ThilI , Philippe Jais , Pascale Grel , Sandrine Mace
IPC分类号： A01K67/027 , A61K38/00 , A61K45/00 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/28 , A61P43/00 , C07K14/47 , C07K16/18 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12Q1/68 , G01N33/15 , G01N33/50 , G01N33/53 , G01N37/00 , C07H21/04 , C07K14/705
摘要： The present invention provides polypeptide and polynucleotide sequences for novel splice variants of the sodium and chloride-dependent glycine transporter type 1 (GlyT1). These polypeptides and polynucleotides are useful in the treatment and diagnosis of disorders such as neurological and psychiatric disorders including schizophrenia. The invention also provides antibodies directed specifically against these novel polypeptides, and kits comprising the herein-described polynucleotides, polypeptides, and/or antibodies.
摘要翻译： 本发明提供了用于钠和氯化物依赖的甘氨酸转运蛋白1型（GlyT1）的新剪接变体的多肽和多核苷酸序列。 这些多肽和多核苷酸可用于治疗和诊断疾病如神经和精神疾病，包括精神分裂症。 本发明还提供了针对这些新型多肽的抗体，以及包含本文描述的多核苷酸，多肽和/或抗体的试剂盒。
-
公开(公告)号：US07358066B2
公开(公告)日：2008-04-15
申请号：US10484690
申请日：2002-07-22
申请人： Gilbert Thill , Philippe Jais , Pascale Grel , Sandrine Mace
发明人： Gilbert Thill , Philippe Jais , Pascale Grel , Sandrine Mace
摘要： The present invention provides polypeptide and polynucleotide sequences for novel splice variants of the sodium and chloride-dependent glycine transporter type 1 (GlyT1). These polypeptides and polynucleotides are useful in the treatment and diagnosis of disorders such as neurological and psychiatric disorders including schizophrenia. The invention also provides antibodies directed specifically against these novel polypeptides, and kits comprising the herein-described polynucleotides, polypeptides, and/or antibodies.
摘要翻译： 本发明提供了用于钠和氯化物依赖的甘氨酸转运蛋白1型（GlyT1）的新剪接变体的多肽和多核苷酸序列。 这些多肽和多核苷酸可用于治疗和诊断疾病如神经和精神疾病，包括精神分裂症。 本发明还提供了针对这些新型多肽的抗体，以及包含本文描述的多核苷酸，多肽和/或抗体的试剂盒。
-
公开(公告)号：US20080201789A1
公开(公告)日：2008-08-21
申请号：US12050255
申请日：2008-03-18
申请人： Gilbert Thill , Philippe Jais , Pascale Grel , Sandrine Mace
发明人： Gilbert Thill , Philippe Jais , Pascale Grel , Sandrine Mace
摘要： The present invention provides polypeptide and polynucleotide sequences for novel splice variants of the sodium and chloride-dependent glycine transporter type 1 (GlyT1). These polypeptides and polynucleotides are useful in the treatment and diagnosis of disorders such as neurological and psychiatric disorders including schizophrenia. The invention also provides antibodies directed specifically against these novel polypeptides, and kits comprising the herein-described polynucleotides, polypeptides, and/or antibodies.
摘要翻译： 本发明提供了用于钠和氯化物依赖的甘氨酸转运蛋白1型（GlyT1）的新剪接变体的多肽和多核苷酸序列。 这些多肽和多核苷酸可用于治疗和诊断疾病如神经和精神疾病，包括精神分裂症。 本发明还提供了针对这些新型多肽的抗体，以及包含本文描述的多核苷酸，多肽和/或抗体的试剂盒。
-
公开(公告)号：US20130042334A1
公开(公告)日：2013-02-14
申请号：US13641584
申请日：2011-04-15
申请人： Philippe Jais
发明人： Philippe Jais
IPC分类号： C12N9/96 , C12N15/85 , C12P19/34 , C12N5/10 , A61K38/54 , A61K48/00 , C12N1/19 , A01K67/027 , A61P35/00 , A61P37/06 , A61P9/00 , A61P9/06 , A61P7/04 , A61P3/10 , A61P31/18 , A61P31/20 , A61P31/14 , A61P31/16 , A61P1/16 , A61P1/00 , A61P25/28 , A61P25/16 , A61P25/14 , A61P25/18 , A61P17/00 , A61P19/04 , A01H5/00 , C12N15/62
CPC分类号： C12P19/34 , A61K38/00 , C07K2319/00 , C12N9/1007 , C12N9/1241 , C12N9/1247 , C12N9/14 , C12Y201/01056 , C12Y306/04013 , Y02A50/411 , Y02A50/469
摘要： The invention provides a chimeric enzyme comprising at least one catalytic domain of a RNA triphosphatase, at least one catalytic domain of a guanylyltransferase, at least one catalytic domain of a N7-guanine methyltransferase, and at least one catalytic domain of a DNA-dependant RNA polymerase. The invention also provides pharmaceutical composition comprising said chimeric enzyme and uses of said chimeric enzyme.
-
公开(公告)号：US08962292B2
公开(公告)日：2015-02-24
申请号：US13641584
申请日：2011-04-15
申请人： Philippe Jais
发明人： Philippe Jais
CPC分类号： C12P19/34 , A61K38/00 , C07K2319/00 , C12N9/1007 , C12N9/1241 , C12N9/1247 , C12N9/14 , C12Y201/01056 , C12Y306/04013 , Y02A50/411 , Y02A50/469
摘要： The invention provides a chimeric enzyme comprising at least one catalytic domain of a RNA triphosphatase, at least one catalytic domain of a guanylyltransferase, at least one catalytic domain of a N7-guanine methyltransferase, and at least one catalytic domain of a DNA-dependant RNA polymerase. The invention also provides pharmaceutical composition comprising said chimeric enzyme and uses of said chimeric enzyme.
摘要翻译： 本发明提供了包含至少一种RNA三磷酸酶的催化结构域，鸟苷酰基转移酶的至少一个催化结构域，N7-鸟嘌呤甲基转移酶的至少一个催化结构域和至少一个DNA依赖性RNA的催化结构域的嵌合酶 聚合酶。 本发明还提供了包含所述嵌合酶的药物组合物和所述嵌合酶的用途。
-
-
-
-
搜索结果
5 条记录 (耗时 0.025 秒)
