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    Benzophenones having an antifungal activity
    7.
    发明授权
    Benzophenones having an antifungal activity 失效
    具有抗真菌活性的二苯甲酮

    公开(公告)号：US5464836A

    公开(公告)日：1995-11-07

    申请号：US131880

    申请日：1993-10-05

    申请人： Giovanni Camaggi ,  Lucio Filippini ,  Marilena Gusmeroli ,  Raul Riva ,  Carlo Garavaglia ,  Luigi Mirenna

    发明人： Giovanni Camaggi ,  Lucio Filippini ,  Marilena Gusmeroli ,  Raul Riva ,  Carlo Garavaglia ,  Luigi Mirenna

    IPC分类号： A01N37/44 ,  A01N35/04 ,  A01N43/84 ,  C07C45/51 ,  C07C49/86 ,  C07C217/22 ,  C07C225/06 ,  C07C225/16 ,  C07C233/69 ,  C07D265/30 ,  C07D279/12 ,  C07D295/092 ,  C07D295/112 ,  A61K31/535 ,  C07C211/27

    CPC分类号： C07D295/088 ,  A01N35/04 ,  C07C217/22 ,  C07C225/16 ,  C07C45/512 ,  C07C49/86 ,  C07D295/112

    摘要： A description follows of benzophenones having an antifungal activity and responding to the general formula (I): ##STR1## wherein: R.sub.1 and R.sub.2, the same or different, represent C.sub.1 -C.sub.6 alkyl groups, C.sub.7 -C.sub.10 arylalkyl groups; or R.sub.1 and R.sub.2, considered jointly with N, represent a C.sub.3 -C.sub.8 heterocyclic group or a C.sub.2 -C.sub.7 heterocyclic group containing a second hetero-atom selected from O and S, said heterocyclic groups being optionally subsituted with one or more C.sub.1 -C.sub.4 alkyl groups;R.sub.3 and R.sub.4, the same or different, represent H atoms, C.sub.1 -C.sub.3 alkyl groups;K represents an oxygen atom or methylene;A represents a benzene group, optionally sustituted with one or more halogen atoms, C.sub.1 -C.sub.4 alkyl or haloalkyl groups, C.sub.1 -C.sub.4 alkoxylics, C.sub.1 -C.sub.4 haloalkoxylics;Y represents a C.sub.6 -C.sub.10 aryl group; said group may be optionally substituted with one or more halogen atomos, C.sub.1 -C.sub.4 alkyl or haloalkyl groups, C.sub.1 -C.sub.4 alkoxylics, C.sub.1 -C.sub.4 haloalkoxylics.

    摘要翻译： 以下描述具有抗真菌活性并对应于通式（I）的二苯甲酮：其中：R1和R2相同或不同，表示C1-C6烷基，C7-C10芳基烷基; 或与N一起考虑的R 1和R 2表示含有选自O和S的第二杂原子的C 3 -C 8杂环基或C 2 -C 7杂环基，所述杂环基任选被一个或多个C 1 -C 4烷基取代 团体 R3和R4相同或不同，表示H原子，C1-C3烷基; K表示氧原子或亚甲基; A表示任选被一个或多个卤素原子取代的苯基，C 1 -C 4烷基或卤代烷基，C 1 -C 4烷氧基，C 1 -C 4卤代烷氧基; Y表示C6-C10芳基; 所述基团可以任选地被一个或多个卤素原子，C 1 -C 4烷基或卤代烷基，C 1 -C 4烷氧基，C 1 -C 4卤代烷氧基取代。