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公开(公告)号:US06844042B1
公开(公告)日:2005-01-18
申请号:US09543281
申请日:2000-04-05
申请人: Guolin Ma , Easen Ho , Theodore Rees , Bo Wei
发明人: Guolin Ma , Easen Ho , Theodore Rees , Bo Wei
CPC分类号: G11B7/122 , G11B7/1387 , Y10T428/21
摘要: An air-incident optical recording medium for use with flying heads has a system of layers, which thermally isolate the disk surface from the active, recording layer.
摘要翻译: 与飞头一起使用的空气入射光记录介质具有层,其将盘表面与活性记录层热隔离。
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公开(公告)号:US20090052289A1
公开(公告)日:2009-02-26
申请号:US11843879
申请日:2007-08-23
申请人: HuaYuan Chen , Bo Wei , YongPeng Chng
发明人: HuaYuan Chen , Bo Wei , YongPeng Chng
IPC分类号: G11B5/58
CPC分类号: G11B27/36 , G11B20/1883 , G11B2220/20 , G11B2220/2516
摘要: The disclosure is directed toward systems and methods of defect description of a data storage medium. In a particular embodiment, a method includes determining a first defect of a data storage medium. The method also includes determining a format of an entry of a defect description table based on the first defect and a location of a second defect of the data storage medium. The format is selected from one of a plurality of formats. The method also includes storing a description of the first defect in the entry of the defect description table in the format.
摘要翻译: 本公开涉及数据存储介质的缺陷描述的系统和方法。 在特定实施例中,一种方法包括确定数据存储介质的第一缺陷。 该方法还包括基于数据存储介质的第一缺陷和第二缺陷的位置来确定缺陷描述表的条目的格式。 格式是从多种格式之一中选择的。 该方法还包括以缺陷描述表的格式存储第一缺陷的描述。
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公开(公告)号:US07078210B2
公开(公告)日:2006-07-18
申请号:US10658661
申请日:2003-09-08
申请人: Ralf M Luche , Bo Wei
发明人: Ralf M Luche , Bo Wei
CPC分类号: G01N33/573 , A61K2039/505 , C12N9/16
摘要: Compositions and methods are provided for the treatment of conditions associated with cell proliferation, cell differentiation and cell survival. In particular, the dual-specificity phosphatase DSP-3, and polypeptide variants thereof that stimulate dephosphorylation of DSP-3 substrates, are provided. The polypeptides may be used, for example, to identify antibodies and other agents that inhibit DSP-3 activity. The polypeptides and agents may be used to modulate cell proliferation, differentiation and survival.
摘要翻译: 提供组合物和方法用于治疗与细胞增殖,细胞分化和细胞存活相关的病症。 特别地,提供了刺激DSP-3底物去磷酸化的双特异性磷酸酶DSP-3及其多肽变体。 多肽可用于例如鉴定抑制DSP-3活性的抗体和其它试剂。 多肽和试剂可用于调节细胞增殖,分化和存活。
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公开(公告)号:US07029898B2
公开(公告)日:2006-04-18
申请号:US10655073
申请日:2003-09-04
申请人: Ralf M. Luche , Bo Wei
发明人: Ralf M. Luche , Bo Wei
CPC分类号: C12N9/16
摘要: Compositions and methods are provided for the treatment of conditions associated with cell proliferation, cell differentiation and cell survival. In particular, the dual-specificity phosphatase DSP-11, and polypeptide variants thereof that stimulate dephosphorylation of DSP-11 substrates, are provided. The polypeptides may be used, for example, to identify antibodies and other agents that inhibit DSP-11 activity. The polypeptides and agents may be used to modulate cell proliferation, differentiation and survival.
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公开(公告)号:US20050075489A1
公开(公告)日:2005-04-07
申请号:US10644554
申请日:2003-08-19
申请人: Ralf Luche , Bo Wei
发明人: Ralf Luche , Bo Wei
IPC分类号: G01N33/50 , A61K39/395 , A61K45/00 , A61P3/00 , A61P35/00 , A61P37/06 , A61P37/08 , A61P43/00 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N9/16 , C12N15/09 , C12N15/55 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , G01N33/577 , G01N33/58 , C07K16/18
CPC分类号: C12Y301/03016 , C12N9/16 , C12Y301/03048
摘要: Compositions and methods are provided for the treatment of conditions associated with cell proliferation, cell differentiation and cell survival. In particular, the dual-specificity phosphatase DSP-5, and polypeptide variants thereof that stimulate dephosphorylation of DSP-5 substrates, are provided. The polypeptides may be used, for example, to identify antibodies and other agents that inhibit DSP-5 activity. The polypeptides and agents may be used to modulate cell proliferation, differentiation and survival.
摘要翻译: 提供组合物和方法用于治疗与细胞增殖,细胞分化和细胞存活相关的病症。 特别地,提供了刺激DSP-5底物去磷酸化的双特异性磷酸酶DSP-5及其多肽变体。 多肽可用于例如鉴定抑制DSP-5活性的抗体和其它试剂。 多肽和试剂可用于调节细胞增殖,分化和存活。
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公开(公告)号:US5838522A
公开(公告)日:1998-11-17
申请号:US794672
申请日:1997-02-03
申请人: Kyriakos Komvopoulos , Ian G. Brown , Bo Wei , Simone Anders , Andre Anders , C. Singh Bhatia
发明人: Kyriakos Komvopoulos , Ian G. Brown , Bo Wei , Simone Anders , Andre Anders , C. Singh Bhatia
IPC分类号: C04B41/00 , C04B41/80 , C23C14/32 , C23C14/48 , G11B5/10 , G11B5/187 , G11B5/255 , G11B5/40 , G11B5/60 , G11B33/10
CPC分类号: C04B41/009 , C04B41/0027 , C04B41/0054 , C04B41/80 , C23C14/325 , C23C14/48 , G11B33/10 , G11B5/10 , G11B5/187 , G11B5/255 , G11B5/40 , G11B5/6005
摘要: Surface modification of magnetic recording heads using plasma immersion ion implantation and deposition is disclosed. This method may be carried out using a vacuum arc deposition system with a metallic or carbon cathode. By operating a plasma gun in a long-pulse mode and biasing the substrate holder with short pulses of a high negative voltage, direct ion implantation, recoil implantation, and surface deposition are combined to modify the near-surface regions of the head or substrate in processing times which may be less than 5 min. The modified regions are atomically mixed into the substrate. This surface modification improves the surface smoothness and hardness and enhances the tribological characteristics under conditions of contact-start-stop and continuous sliding. These results are obtained while maintaining original tolerances.
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公开(公告)号:US5650900A
公开(公告)日:1997-07-22
申请号:US680591
申请日:1996-07-12
申请人: Bo Wei , Dallas W. Meyer , Venkat R. Koka
发明人: Bo Wei , Dallas W. Meyer , Venkat R. Koka
CPC分类号: G11B5/725 , G11B5/82 , G11B5/8408
摘要: A magnetic disc for a computer disc drive has distinct zones of differing lubricant thickness. A bonded+mobile zone covers a portion of the disc which preferably coincides with the landing zone. A zone of different lubricant thickness, such as lubricant-free, bonded-only or mostly-bonded, covers a different portion of the disc such as over the data zone. After a uniform layer of lubricant is coated over the disc surface, lubricant can be removed from distinct zones by solvent removal over a periphery of the disc and by removal by laser. The lubricant removal from distinct zones can occur either before or after bonding. Multiple lubricant thickness zones may be used, and the lubricant thickness profile over the entire disc can be controlled as desired.
摘要翻译: 用于计算机磁盘驱动器的磁盘具有不同的润滑剂厚度区域。 粘结+移动区覆盖盘的一部分,优选地与着陆区重合。 不同润滑剂厚度的区域,例如无润滑剂,仅粘合或大部分粘合的区域覆盖盘的不同部分,例如数据区域。 在盘表面上涂覆均匀的润滑剂层之后,可以通过在圆周上通过溶剂去除并通过激光去除从不同的区域去除润滑剂。 不同区域的润滑剂去除可能在粘合之前或之后发生。 可以使用多个润滑剂厚度区,并且可以根据需要控制整个盘上的润滑剂厚度分布。
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公开(公告)号:US09146683B2
公开(公告)日:2015-09-29
申请号:US13090695
申请日:2011-04-20
申请人: Bo Wei , Steven TianChye Cheok , YongPeng Chng , CheeSeng Toh
发明人: Bo Wei , Steven TianChye Cheok , YongPeng Chng , CheeSeng Toh
CPC分类号: G06F3/0613 , G06F3/0619 , G06F3/064 , G06F3/0647 , G06F3/0676 , G06F12/0292
摘要: A mapping table is modified to match one or more specified storage conditions of data stored in or expected to be stored in one or more logical block address ranges to physical addresses within a storage drive having performance characteristics that satisfy the specified storage conditions. For example, the performance characteristics may be a reliability of the physical location within the storage drive or a data throughput range of read/write operations. Existing data is moved and/or new data is written to physical addresses on the storage media possessing the performance characteristic(s), according to the mapping table. Further, a standard seeding or a seeding override for the re-mapped logical block addresses can prevent read operations from inadvertently reading incorrect physical addresses corresponding to the re-mapped logical block addresses.
摘要翻译: 修改映射表以将存储在或预期存储在一个或多个逻辑块地址范围中的数据的一个或多个指定存储条件与具有满足指定存储条件的性能特性的存储驱动器内的物理地址相匹配。 例如,性能特征可以是存储驱动器内的物理位置的可靠性或读/写操作的数据吞吐范围。 根据映射表,现有数据被移动和/或新数据被写入具有性能特征的存储介质上的物理地址。 此外,用于重新映射的逻辑块地址的标准播种或播种覆盖可以防止读取操作无意中读取与重新映射的逻辑块地址相对应的不正确的物理地址。
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公开(公告)号:US20110128815A1
公开(公告)日:2011-06-02
申请号:US12957145
申请日:2010-11-30
申请人: Bo Wei
发明人: Bo Wei
CPC分类号: A61B8/4405 , B62B5/00 , Y10T29/49826 , Y10T29/49959
摘要: A cart for use with an ultrasonic imaging apparatus, comprising: a supporting part, a cart body and a bottom part; said cart body is connected to the supporting part and the bottom part; said supporting part is provided with an interface thereon for supporting and connecting the ultrasonic imaging apparatus; said cart body is an elevator structure provided with a power cable therein for supplying power to the ultrasonic imaging apparatus; the lower portion of the supporting part and the upper portion of the bottom part are both provided with a power socket; said power cable is a coiled cord structure, and its two ends are connected to the two power sockets; a stretchable elastic component having elastic recovery is provided inside the coiled cord structure of the power cable.
摘要翻译: 一种与超声波成像装置一起使用的手推车,包括:支撑部件,手推车主体和底部部分; 所述车体与所述支撑部和所述底部连接; 所述支撑部分设置有用于支撑和连接超声波成像装置的界面; 所述车体是在其中设置有用于向超声波成像装置供电的电力电缆的电梯结构; 支撑部分的下部和底部的上部均设有电源插座; 所述电力电缆是线圈结构,其两端连接到两个电源插座; 具有弹性回复的伸缩性弹性部件设置在电力电缆的线圈式电线结构的内部。
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公开(公告)号:US20100267037A1
公开(公告)日:2010-10-21
申请号:US12761330
申请日:2010-04-15
申请人: Aya M. Westbrook , Robert H. Schiestl , Bo Wei , Jonathan Braun
发明人: Aya M. Westbrook , Robert H. Schiestl , Bo Wei , Jonathan Braun
IPC分类号: C12Q1/68
CPC分类号: C12Q1/686 , C12Q1/6883 , C12Q2600/158 , G01N27/447 , G01N33/5014 , G01N33/6875
摘要: The invention provides a method for detection of inflammatory disease in a subject that comprises assaying a test sample of peripheral blood from the subject for a marker of DNA damage. An elevated amount of marker present in the test sample compared to control sample is indicative of inflammatory disease activity, including sub-clinical inflammation. The method can be adapted for quantitatively monitoring the efficacy of treatment of inflammatory disease in a subject. Markers of DNA damage include single- and/or double-stranded breaks in leukocytes, oxidative DNA damage in leukocytes, or a marker of nitric oxide oxidative activity (protein nitrosylation in leukocytes). The inflammatory disease can be inflammatory bowel disease (ulcerative colitis or Crohn's disease). The invention may also be used for detection of other types of inflammatory disease, such as non-immune intestinal inflammatory disease (diverticulitis, pseudomembranous colitis), autoimmune diseases (rheumatoid arthritis, lupus, multiple sclerosis, psoriasis, uveitis, vasculitis), or non-immune lung diseases (asthma, chronic obstructive lung disease, and interstitial pneumonitis). This unexpected discovery of markers of genotoxicity present in circulating leukocytes enables detection of inflammation occurring at a localized site with a relatively simple and minimally invasive assay using peripheral blood.
摘要翻译: 本发明提供了一种用于检测受试者的炎性疾病的方法,其包括测定来自受试者的外周血的测试样品用于DNA损伤的标记。 与对照样品相比,存在于测试样品中的标记物量增加指示炎症性疾病活动,包括亚临床炎症。 该方法可以适应于定量监测受试者中炎性疾病治疗的功效。 DNA损伤的标记包括白细胞中的单链和/或双链断裂,白细胞中的氧化性DNA损伤或一氧化氮氧化活性的标记(白细胞中的蛋白质亚硝基化)。 炎性疾病可以是炎性肠病(溃疡性结肠炎或克罗恩病)。 本发明还可用于检测其它类型的炎性疾病,例如非免疫性肠炎性炎症(憩室炎,假膜性结肠炎),自身免疫性疾病(类风湿性关节炎,狼疮,多发性硬化,牛皮癣,葡萄膜炎,血管炎) 免疫性肺部疾病(哮喘,慢性阻塞性肺病和间质性肺炎)。 存在于循环白细胞中的遗传毒性标志物的这种意想不到的发现使得能够使用外周血使用相对简单和微创的测定来检测在局部位点发生的炎症。
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