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公开(公告)号：US11506534B2
公开(公告)日：2022-11-22
申请号：US16472129
申请日：2017-10-24
Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
Inventor： Takeshi Ishida , Isao Yamazaki , Sakuichiro Adachi , Shin Imamura
Abstract: An automatic analysis apparatus comprises: a light source generating light having a center wavelength equal to or shorter than 340 nm; a fluorescent substance excited by the light source light, and generates light together with transmitted light from the light source, having a wavelength of 340 nm to 800 nm; a condenser lens; at least one slit; a reaction cell holding a reaction solution where a specimen and reagent are mixed, and that the light source light and the light from the fluorescent substance enter; and a detector that detects light transmitted through the reaction cell. The light source, fluorescent substance, condenser lens, and slit are provided along a straight light corresponding to the optical axis. The width of the slit's opening is equal to or narrower than the width of a ray forming an image of the light source at the position of the slit.
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公开(公告)号：US10067152B2
公开(公告)日：2018-09-04
申请号：US15111006
申请日：2015-01-13
Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
Inventor： Masaru Miyazaki , Takamichi Mori , Kazuhiro Nakamura , Isao Yamazaki
Abstract: An automatic analyzer has a washing tank providing water for washing a reagent or sample probe is. The washing water from a washing nozzle spreads from a throttle portion and is divided into right and left flows after colliding with a vent plate provided in an overflow portion of the washing tank. The washing water flows between the vent plate and the inner wall of the overflow portion, and the flows join behind the vent plate. After joining, the washing water flows downward along the vent plate and the inner wall of the overflow portion and then is drained. Because a space is created between the washing water which has collided with the vent plate and the washing water joined behind the vent plate, the washing water is prevented from completely covering the overflow portion, and the airflow can be secured during the drainage.
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公开(公告)号：US09817013B2
公开(公告)日：2017-11-14
申请号：US14185037
申请日：2014-02-20
Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
Inventor： Hideyuki Yanami , Isao Yamazaki , Masaaki Hanawa , Hitoshi Otake
CPC classification number: G01N35/1095 , B01F11/008 , G01N35/0092 , G01N35/021 , G01N35/025 , G01N35/1002 , G01N35/1004 , G01N35/1009 , G01N35/1011 , G01N35/1016 , G01N35/1065 , G01N35/109 , G01N2035/00237 , G01N2035/0406 , G01N2035/1018 , G01N2035/1025 , G01N2035/1076 , G01N2035/1086 , Y10T436/11 , Y10T436/111666 , Y10T436/114998 , Y10T436/2575
Abstract: The invention provides a small-sized automatic analyzer being compact, enabling a large number of analysis items to be carried out, and having a high processing speed. The automatic analyzer is particularly suitably applied to a medical analyzer used for qualitative/quantitative analysis of living body samples, such as urine and blood. A plurality of sample dispensing mechanism s capable of being operated independently of each other are provided to suck a sample from any one of a plurality of sample suction positions and to discharge the sucked sample to any one of a plurality of positions on a reaction disk. The automatic analyzer having a high processing capability can be thus realized without increasing the system size.
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公开(公告)号：US20150198525A1
公开(公告)日：2015-07-16
申请号：US14670861
申请日：2015-03-27
Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
Inventor： Sakuichiro Adachi , Muneo Maeshima , Isao Yamazaki , Tomonori Mimura
IPC: G01N21/51
CPC classification number: G01N21/51 , G01N15/0205 , G01N21/253 , G01N2015/0065 , G01N2035/00396 , G01N2035/0453
Abstract: To be adapted to various types of latex reagents for detecting scattered light and thereby measuring agglutination reactions with high sensitivity while sufficiently ensuring integration time. To be adapted to various types of latex particles of different particle sizes, a plurality of light receivers are arranged in a plane perpendicular to the direction of cell movement by rotation of a cell disk. To ensure sufficient integration time, the angle between the optical axis of the irradiation light and each of a plurality of optical axes of scattered light viewed from above the cell is made equal to or less than 17.7° including a mounting error.
Abstract translation: 适用于各种类型的用于检测散射光的乳胶试剂，从而以高灵敏度测量凝集反应，同时充分确保积分时间。 为了适应于各种类型的不同粒度的胶乳颗粒，多个光接收器通过旋转细胞盘而布置在垂直于细胞移动方向的平面中。 为了确保足够的积分时间，使得照射光的光轴与从电池单元的上方观察的散射光的多个光轴中的每一个之间的角度等于或小于包括安装误差的17.7°。
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公开(公告)号：US08632725B2
公开(公告)日：2014-01-21
申请号：US13927209
申请日：2013-06-26
Applicant: Hitachi High-Technologies Corporation
Inventor： Isao Yamazaki , Ryuji Tao , Katsuaki Takahashi
CPC classification number: G01N21/75 , G01N35/0092 , G01N35/025 , G01N35/1002 , G01N35/1083 , G01N2035/0094 , G01N2035/1076 , Y10T436/11 , Y10T436/113332 , Y10T436/115831 , Y10T436/116664 , Y10T436/119163 , Y10T436/12
Abstract: An automatic analyzer according to the present invention is compact, mounting great number of reagents, having high processing ability. Reagent disks are arranged at inside and outside of a reaction disk. A reagent probe can inject a reagent into the position which is common position of both reagent disks. One of plural reagent probes approaches to one of reagent disks at one cycle. Plural reagent probes alternatively approach to the reagent disk. Therefore, the first reagents and the second reagents can be placed on both reagent disks. The mounting number of reagents can be increased without enlarging an analyzer. The cycle time can be shortened to make an automatic analyzer to have high processing ability.
Abstract translation: 根据本发明的自动分析仪是紧凑的，安装大量试剂，具有高处理能力。 试剂盘布置在反应盘的内部和外部。 试剂探针可以将试剂注入到两个试剂盘的共同位置的位置。 多个试剂探针之一在一个循环中接近一个试剂盘。 多个试剂探针交替接近试剂盘。 因此，可以将第一试剂和第二试剂置于两个试剂盘上。 可以在不扩大分析仪的情况下增加试剂的安装数量。 可以缩短循环时间，使自动分析仪具有较高的处理能力。
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Patent Agency Ranking
公开(公告)号：US11293934B2
公开(公告)日：2022-04-05
申请号：US16307787
申请日：2017-04-24
Inventor： Takeshi Ishida , Sakuichiro Adachi , Yoshihiro Yamashita , Shunichirou Nobuki , Hisashi Yabutani , Isao Yamazaki , Michaela Windfuhr , Bernhard Hauptmann , Simon Kuester
Abstract: An automatic analyzer is equipped with a sterilization mechanism removably attached to an opening of a container that holds a reagent and having an ultraviolet light generation section that radiates ultraviolet light; a suction nozzle removably attached, together with the sterilization mechanism, to the opening of the container; an analysis section adding the reagent drawn in by suction from the container via the suction nozzle to the reagent, and executing an analysis operation; and a control section exercising variable control over an irradiation light intensity of the ultraviolet light generated by the ultraviolet light generation section.
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公开(公告)号：US11162965B2
公开(公告)日：2021-11-02
申请号：US16463965
申请日：2017-11-08
Applicant: Hitachi High-Technologies Corporation
Inventor： Shinji Azuma , Isao Yamazaki , Masashi Fukaya , Takumi Ito
Abstract: The object of the invention is to avoid a decrease in dispensing accuracy of a sample, a reagent, or the like as a temperature changes. In an automatic analyzer, a dispensing nozzle sucks the sample from a sample container holding the sample and discharges the sample to a reaction container. A syringe pump controls an amount of change in a volume of water. A first pipe connects the dispensing nozzle and the syringe pump. An electromagnetic valve flows or stops the water. A second pipe connects the electromagnetic valve and the syringe pump. A branch pipe branches the water. A third pipe connects the electromagnetic valve and the branch pipe. A case accommodates at least the syringe pump, the first pipe, the electromagnetic valve, the second pipe, the branch pipe, and the third pipe. Further, the third pipe includes a heat exchange unit that performs heat exchange of the water.
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公开(公告)号：US11143665B2
公开(公告)日：2021-10-12
申请号：US16331594
申请日：2017-09-14
Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
Inventor： Akihiro Yasui , Gorou Yoshida , Yoshiki Muramatsu , Isao Yamazaki
Abstract: An automatic analyzer (100) includes: a storage unit (21b) that stores various parameters of the automatic analyzer (100) in association with each of elevations used in the automatic analyzers (100), the parameters being optimized for each of the elevations; an input unit (21d) that acquires information of an elevation at which the automatic analyzer (100) is provided; and a controller (21a) that reads the parameters stored in the storage unit (21b) and sets the read parameters to the automatic analyzer (100) based on the elevation acquired by the input unit (21d). As a result, various parameters can be easily adjusted according to a usage environment of the device.
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公开(公告)号：US10113962B2
公开(公告)日：2018-10-30
申请号：US14670861
申请日：2015-03-27
Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
Inventor： Sakuichiro Adachi , Muneo Maeshima , Isao Yamazaki , Tomonori Mimura
Abstract: To be adapted to various types of latex reagents for detecting scattered light and thereby measuring agglutination reactions with high sensitivity while sufficiently ensuring integration time. To be adapted to various types of latex particles of different particle sizes, a plurality of light receivers are arranged in a plane perpendicular to the direction of cell movement by rotation of a cell disk. To ensure sufficient integration time, the angle between the optical axis of the irradiation light and each of a plurality of optical axes of scattered light viewed from above the cell is made equal to or less than 17.7° including a mounting error.
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公开(公告)号：US09023282B2
公开(公告)日：2015-05-05
申请号：US14484384
申请日：2014-09-12
Applicant: Hitachi High-Technologies Corporation
Inventor： Sakuichiro Adachi , Muneo Maeshima , Isao Yamazaki , Tomonori Mimura
CPC classification number: G01N21/51 , G01N15/0205 , G01N21/253 , G01N2015/0065 , G01N2035/00396 , G01N2035/0453
Abstract: To be adapted to various types of latex reagents for detecting scattered light and thereby measuring agglutination reactions with high sensitivity while sufficiently ensuring integration time. To be adapted to various types of latex particles of different particle sizes, a plurality of light receivers are arranged in a plane perpendicular to the direction of cell movement by rotation of a cell disk. To ensure sufficient integration time, the angle between the optical axis of the irradiation light and each of a plurality of optical axes of scattered light viewed from above the cell is made equal to or less than 17.7° including a mounting error.
Abstract translation: 适用于各种类型的用于检测散射光的乳胶试剂，从而以高灵敏度测量凝集反应，同时充分确保积分时间。 为了适应于各种类型的不同粒度的胶乳颗粒，多个光接收器通过旋转细胞盘而布置在垂直于细胞移动方向的平面中。 为了确保足够的积分时间，使得照射光的光轴与从电池单元的上方观察的散射光的多个光轴中的每一个之间的角度等于或小于包括安装误差的17.7°。
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