摘要:
Disclosed herein are electronic devices, such as, for example, televisions, stereo systems, diagnostic equipment, cell phones, desktop or laptop PCs, medical pulse generators, or etc., including an integrated circuit including a printed circuit board including multiple layers and a wire bond pad. The multiple layers are sandwiched together in a planar unitary structure including a top surface, a bottom surface and a structure edge extending between the top surface and the bottom surface. The multiple layers include a first organic substrate layer joined to a second organic substrate layer. Each organic substrate layer includes a layer edge and a peripheral surface adjacent the layer edge. Each layer edge forms part of the structure edge. The wire bond pad includes an outer face, an inner face generally opposite the outer face, and a first rib. The inner face extends along the structure edge. The first rib projects generally perpendicular from the inner face between the first organic substrate layer and the second organic substrate layer and extends along the peripheral surface of at least one of the first organic substrate layer or the second organic substrate layer.
摘要:
The present disclosure provides methods for treating a subject having a HER2 non-amplified (HER2-negative) cancer or low HER2 expressing (HER2-low) cancer, comprising detecting expression of a BCAR4 gene fusion in a biological sample from the subject. If expression of the BCAR4 gene fusion is detected, a HER2-targeted cancer treatment is administered to the subject; if expression of the BCAR4 gene fusion is not detected, a cancer treatment that is not HER2-targeted is administered to the subject. Methods of predicting response to a HER2-targeted cancer treatment and detecting BCAR4 or BCAR4 gene fusion activation are also provided.
摘要:
The present disclosure discloses a non-invasive wireless glucose level monitoring device. The device is fitted into a contact lens and can analyze glucose levels in tear fluid. The results of the analysis can be continuously transmitted to a nearby receiver and uploaded to a computer, mobile device or server.
摘要:
The present invention discloses an air energy boiler and belongs to the technical field of energy conversion. A crankshaft of the boiler is fixed at the output end of a rotating unit. The crankshaft is provided with at least one bulge. A driving piston of each conversion assembly is arranged in an air cavity in a reciprocating motion. The driving piston divides the air cavity into a first cavity and a second cavity. A wrist pin is arranged in the second cavity, and the wrist pin is fixed and connected with the driving piston. Both ends of a piston rod is rotatably connected with the wrist pin and the corresponding bulge respectively. The first cavity is provided with an air intake. Multiple heating pipes are in communication with the first cavity at one end and stretch into the boiler body at the other end. The boiler body is sealed and stores water, and the boiler body is provided with a steam outlet, wherein the steam outlet of the boiler body is connected to various terminals through the use of pipelines. Since air is used as the heat source, no conditional limitations exist for installation, and it is safe to use and saves energy and electricity.
摘要:
The present disclosure relates to a FMCW Light Detection and Ranging system, a wave train of carrier frequency is modulated in narrow-band sequence, an delay interferometer with in-phase and quadrature outputs extracts the phase of this frequency modulation, and a coherent receiver with in-phase and quadrature outputs detects the phase of reflected light from a remote object, the ratio between two phases determines the distance of the remote object.
摘要:
The therapeutic eye mask includes a multi-layer composite main body having a heater plate and a plurality of vibrators mounted therein. The heater plate is located over the wear's eyes when the mask is worn. The vibrators are located in upper locations relative to the heater plate. The heater plate and the vibrators are operated by a pulse control circuit and a timer which are operative by an electrical controller connected to an electrical supply with a USB connector. A space cloth plate and a plurality of magnet disks are provided in the main body. The electrical controller has a first switch operative to connect the eye mask to the electrical supply and a second switch is operative to facilitate the user in choosing selective massage motions to provide effective therapeutic operation.
摘要:
The present disclosure discloses a non-invasive wireless glucose level monitoring device. The device is fitted into a contact lens and can analyze glucose levels in tear fluid. The results of the analysis can be continuously transmitted to a nearby receiver and uploaded to a computer, mobile device or server.
摘要:
A charging count method and a charging count device are provided. The method includes: acquiring an industry user identifier corresponding to a user equipment according to a user equipment identifier or an access point name APN used by the user equipment; and performing charging count on an industry user corresponding to the industry user identifier. Through the charging count method and the charging count device, charging processing of a charging count network element is optimized, thereby greatly reducing a charging processing load of the charging count network element, and ensuring normal operation of the charging count network element.
摘要:
A pet food composition having at least two carotenoids. The carotenoids can include a keto-carotenoid and at least one non-keto-carotenoid. The keto-carotenoid can include astaxanthin. The keto-carotenoid can include astaxanthin ester. The non-keto-carotenoid can include beta-carotene and/or lutein.
摘要:
A chimeric phosphorylation indicator (CPI) as provided herein can contain a donor molecule, a phosphorylatable domain, a phosphoaminoacid binding domain (PAABD), and an acceptor molecule. Where the phosphorylatable domain is phosphorylatable by protein kinase C (PKC), the CPI is a c-kinase activity reporter (CKAR). Donor and acceptor molecules may be, independently, fluorescent proteins such as non-oligomerizing fluorescent proteins. A CPI can contain a phosphorylatable polypeptide and a fluorescent protein; the phosphorylatable polypeptide may be contained within the sequence of the fluorescent protein, or the fluorescent protein may be contained within the sequence of the phosphorylatable polypeptide. The spatiotemporal properties of the PKC signal pathway may be tested with CKAR, calcium-sensing fluorophores and FRET-based translocation assays. Polynucleotides encoding such CPIs, and kits containing the indicators and/or the polynucleotides, are provided. A method of using the chimeric phosphorylation indicators to detect a kinase or phosphatase in a sample is provided.